Nicholas M. Riley

Also affiliated with MetroHealth Medical Center, Case Western Reserve University, Stanford University

Biochemistry, Genetics and Molecular BiologyChemistryMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge

(2023)10.1158/0008-5472.22431249

Top 100%

0DataRank

Top 100%0 citations

Fernando Jose Garcia-Marques, Loukia Georgiou Karacosta, Weiruo Zhang, Abel Bermudez, Nicholas M. Riley +9 more

Papers

Driven by 67 papers — median percentile 0. Top paper: “Deciphering O -glycoprotease substrate preferences with O-Pair Search”.

Deciphering O -glycoprotease substrate preferences with O-Pair Search

Molecular Omics(2022)10.1039/d2mo00244b

N/A

0.999DataRank · unranked

35 citations

Carolyn R. Bertozzi, Nicholas M. Riley

A Pragmatic Guide to Enrichment Strategies for Mass Spectrometry–Based Glycoproteomics

Molecular & Cellular Proteomics(2020)10.1074/mcp.r120.002277

N/A

0.823DataRank · unranked

241 citations

Carolyn R. Bertozzi, Sharon J. Pitteri, Nicholas M. Riley

Instrumentation at the Leading Edge of Proteomics

Analytical Chemistry(2024)10.1021/acs.analchem.3c04497

N/A

0.654DataRank · unranked

77 citations

Joshua J. Coon, Nicholas M. Riley, Trenton M. Peters-Clarke

Practical Effects of Intramolecular Hydrogen Rearrangement in Electron Transfer Dissociation-Based Proteomics

Journal of the American Society for Mass Spectrometry(2021)10.1021/jasms.1c00284

N/A

0.396DataRank · unranked

13 citations

Nicholas M. Riley, Michael S. Westphall, Joshua J. Coon, Trenton M. Peters-Clarke

Instrumentation at the leading edge of proteomics

ChemRxiv(2023)10.26434/chemrxiv-2023-8l72m

N/A

0.360DataRank · unranked

10 citations

Joshua J. Coon, Nicholas M. Riley, Trenton M. Peters-Clarke

Autonomous Dissociation-type Selection for Glycoproteomics Using a Real-Time Library Search

Journal of Proteome Research(2024)10.1021/acs.jproteome.4c00723

N/A

0.330DataRank · unranked

8 citations

Tim S. Veth, William D. Barshop, Jacob H. Russell, Kathryn Kothlow, Jesse D. Canterbury +8 more

Optimal Dissociation Methods Differ for N- and O-glycopeptides

ChemRxiv(2020)10.26434/chemrxiv.12062685.v1

N/A

0.292DataRank · unranked

6 citations

Stacy A. Malaker, Marc D. Drießen, Carolyn R. Bertozzi, Nicholas M. Riley

Optimal Dissociation Methods Differ for N- and O-glycopeptides

ChemRxiv(2020)10.26434/chemrxiv.12062685

N/A

0.186DataRank · unranked

2 citations

Stacy A. Malaker, Marc D. Drießen, Carolyn R. Bertozzi, Nicholas M. Riley

Optimal Dissociation Methods Differ for N- and O-glycopeptides

ChemRxiv(2020)10.26434/chemrxiv.12062685.v2

N/A

0DataRank · unranked

4 citations

Stacy A. Malaker, Marc D. Drießen, Carolyn R. Bertozzi, Nicholas M. Riley

Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19

ChemRxiv(2020)10.26434/chemrxiv.13378148.v1

N/A

0DataRank · unranked

4 citations

Aaron J. Wilk, Nicholas M. Riley, Jessica C. Stark, Samuel Yang, Angela J. Rogers +5 more

Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis

ChemRxiv(2020)10.26434/chemrxiv.12643220

N/A

0DataRank · unranked

3 citations

Stacy A. Malaker, Carolyn R. Bertozzi, Nicholas M. Riley

Lysosome Targeting Chimeras (LYTACs) That Engage a Liver-Specific Asialoglycoprotein Receptor for Targeted Protein Degradation

ChemRxiv(2020)10.26434/chemrxiv.12736778

N/A

0DataRank · unranked

2 citations

Steven M. Banik, Caitlyn L. Miller, Nicholas M. Riley, Jennifer R. Cochran, Carolyn R. Bertozzi +1 more

Modulation of Immune Cell Reactivity with Cis-Binding Siglec Agonist

ChemRxiv(2020)10.26434/chemrxiv.12598655.v1

N/A

0DataRank · unranked

1 citations

S. Y. Chiu, Nicholas M. Riley, Carolyn R. Bertozzi, Corleone S. Delaveris

Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis

(2020)10.26434/chemrxiv.12643220.v1

N/A

0DataRank · unranked

0 citations

Stacy A. Malaker, Carolyn R. Bertozzi, Nicholas M. Riley

Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis

ChemRxiv(2020)10.26434/chemrxiv.12643220.v2

N/A

0DataRank · unranked

0 citations

Stacy A. Malaker, Carolyn R. Bertozzi, Nicholas M. Riley

Modulation of Immune Cell Reactivity with Cis-Binding Siglec Agonist

ChemRxiv(2020)10.26434/chemrxiv.12598655

N/A

0DataRank · unranked

0 citations

Shannon Chiu, Nicholas M. Riley, Carolyn R. Bertozzi, Corleone S. Delaveris

LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation

Nature Chemical Biology(2021)10.1038/s41589-021-00770-1

N/A

0DataRank · unranked

594 citations

Steven M. Banik, Caitlyn L. Miller, Nicholas M. Riley, Jennifer R. Cochran, Carolyn R. Bertozzi +1 more

Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2015024118

N/A

0DataRank · unranked

153 citations

Leonhard Möckl, Stacy A. Malaker, Kayvon Pedram, Gaelen T. Hess, Nicholas M. Riley +6 more

Modulation of immune cell reactivity with cis -binding Siglec agonists

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2012408118

N/A

0DataRank · unranked

69 citations

Shannon H. Chiu, Nicholas M. Riley, Carolyn R. Bertozzi, Corleone S. Delaveris

Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge

Cancer Research(2021)10.1158/0008-5472.can-21-1705

N/A

0DataRank · unranked

42 citations

Fernando Jose Garcia-Marques, Loukia Georgiou Karacosta, Weiruo Zhang, Abel Bermudez, Nicholas M. Riley +9 more

Protocol for cell type-specific labeling, enrichment, and proteomic profiling of plasma proteins in mice

STAR Protocols(2021)10.1016/j.xpro.2021.101014

N/A

0DataRank · unranked

9 citations

Nicholas M. Riley, Xuchao Lyu, Carolyn R. Bertozzi, Jonathan Z. Long, Wei Wei

Revealing the human mucinome

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.27.428510

N/A

0DataRank · unranked

12 citations

Nicholas M. Riley, D. Judy Shon, Kayvon Pedram, Venkatesh Krishnan, Oliver Dorigo +2 more

Multi-Omics Analysis of Fibroblasts from the Invasive Tumor Edge Reveals that Tumor-Stroma Crosstalk Induces O-glycosylation of the CDK4-pRB Axis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.28.446229

N/A

0DataRank · unranked

1 citations

Fernando Jose Garcia Marques, Loukia Georgiou Karacosta, Weiruo Zhang, Abel Bermudez, Nicholas M. Riley +8 more

Cell Type‐Selective Secretome Profiling In Vivo

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.00290

N/A

0DataRank · unranked

0 citations

Wei Wei, Andrew C. Yang, Joon Kim, S. P. Terrell, Vernoica Li +4 more

Revealing the human mucinome

Nature Communications(2022)10.1038/s41467-022-31062-4

N/A

0DataRank · unranked

105 citations

Nicholas M. Riley, D. Judy Shon, Kayvon Pedram, Venkatesh Krishnan, Oliver Dorigo +2 more

Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.101917

N/A

0DataRank · unranked

29 citations

Daniel Fernández, Nicholas M. Riley, Michael J. Ferracane, Carolyn R. Bertozzi, D. Judy Shon

Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2117105119

N/A

0DataRank · unranked

19 citations

Nouf N. Laqtom, D. Judy Shon, Alessandro Di Spiezio, Nicholas M. Riley, Paul Säftig +3 more

Measuring the multifaceted roles of mucin-domain glycoproteins in cancer

Advances in cancer research(2022)10.1016/bs.acr.2022.09.001

N/A

0DataRank · unranked

15 citations

Ru Wen, Carolyn R. Bertozzi, James D. Brooks, Sharon J. Pitteri, Nicholas M. Riley

Antibody-lectin chimeras for glyco-immune checkpoint blockade

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.26.513931

N/A

0DataRank · unranked

16 citations

Melissa A. Gray, Simon Wisnovsky, Itziar Ibarlucea-Benitez, Marta Lustig, Nicholas M. Riley +8 more

Design of a mucin-selective protease for targeted degradation of cancer-associated mucins

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.20.492748

N/A

0DataRank · unranked

10 citations

D. Judy Shon, Gabrielle S. Tender, Natália Rodrigues Mantuano, Jason J. Northey, Kevin J. Metcalf +13 more

Deciphering O-glycoprotease substrate preferences with O-Pair Search

ChemRxiv(2022)10.26434/chemrxiv-2022-pxnv9

N/A

0DataRank · unranked

0 citations

Carolyn R. Bertozzi, Nicholas M. Riley

Deciphering O-glycoprotease substrate preferences with O-Pair Search

ChemRxiv(2022)10.26434/chemrxiv-2022-pxnv9-v2

N/A

0DataRank · unranked

0 citations

Carolyn R. Bertozzi, Nicholas M. Riley

Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras

Science(2023)10.1126/science.adf6249

N/A

0DataRank · unranked

166 citations

Nicholas M. Riley, Roarke A. Kamber, Simon Wisnovsky, S. Hase, Michael C. Bassik +3 more

Organism-wide, cell-type-specific secretome mapping of exercise training in mice

Cell Metabolism(2023)10.1016/j.cmet.2023.04.011

N/A

0DataRank · unranked

90 citations

Nicholas M. Riley, Xuchao Lyu, Xiaotao Shen, Jing Guo, Steffen H. Raun +12 more

Design of a mucin-selective protease for targeted degradation of cancer-associated mucins

Nature Biotechnology(2023)10.1038/s41587-023-01840-6

N/A

0DataRank · unranked

88 citations

D. Judy Shon, Gabrielle S. Tender, Natália Rodrigues Mantuano, Jason J. Northey, Kevin J. Metcalf +14 more

The glycoimmune checkpoint receptor Siglec-7 interacts with T-cell ligands and regulates T-cell activation

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105579

N/A

0DataRank · unranked

38 citations

J.M. Daly, Olivia Drummond-Guy, Vignesh Krishnamoorthy, Jessica C. Stark, Nicholas M. Riley +4 more

Microglia Mediate Contact-Independent Neuronal Network Remodeling via Secreted Neuraminidase-3 Associated with Extracellular Vesicles

ACS Central Science(2023)10.1021/acscentsci.3c01066

N/A

0DataRank · unranked

21 citations

Catherine L. Wang, Nicholas M. Riley, Sherry Li, Rishikesh U. Kulkarni, Carolyn R. Bertozzi +1 more

Reducing Disparities in No Show Rates Using Predictive Model-Driven Live Appointment Reminders for At-Risk Patients: a Randomized Controlled Quality Improvement Initiative

Journal of General Internal Medicine(2023)10.1007/s11606-023-08209-0

N/A

0DataRank · unranked

18 citations

Jessica Higginbotham, Nicholas M. Riley, David C. Kaelber, Brook Watts, Yasir Tarabichi

The 2022 Nobel Prize in Chemistry—sweet!

Glycobiology(2023)10.1093/glycob/cwad016

N/A

0DataRank · unranked

7 citations

Stacy A. Malaker, Nicholas M. Riley, Jennifer J. Kohler, Michael Boyce

Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104755

N/A

0DataRank · unranked

6 citations

Stacy A. Malaker, Nicholas M. Riley, Idalia Perez, Nayla M. Abney, Melissa A. Gray +4 more

Galectin-3 does not interact with RNA directly

Glycobiology(2023)10.1093/glycob/cwad076

N/A

0DataRank · unranked

3 citations

Nicholas M. Riley, Ryan A. Flynn, David S. Roberts, Carolyn R. Bertozzi, Egan L. Peltan

Comprehensive Overview of Bottom-up Proteomics using Mass Spectrometry

PubMed(2023)10.48550/arxiv.2311.07791

N/A

0DataRank · unranked

8 citations

Rex, Devasahayam Arokia Balaya, Dina Schuster, Benjamin A. Neely, Germán L. Rosano, Norbert Volkmar +14 more

Microglia mediate contact-independent neuronal pruning via secreted Neuraminidase-3 associated with extracellular vesicles

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.21.554214

N/A

0DataRank · unranked

5 citations

Catherine L. Wang, Nicholas M. Riley, Sherry Li, Rishikesh U. Kulkarni, Carolyn R. Bertozzi +1 more

The microenvironment dictates glycocalyx construction and immune surveillance

Research Square(2023)10.21203/rs.3.rs-3164966/v1

N/A

0DataRank · unranked

2 citations

Sangwoo Park, Greg A. Timblin, Alicia Richards, Nicholas Twells, Nicholas M. Riley +19 more

517 Blocking Siglec-7/9-sialic acid interactions induces immune cell-mediated suppression of prostate cancer

Regular and Young Investigator Award Abstracts(2023)10.1136/jitc-2023-sitc2023.0517

N/A

0DataRank · unranked

1 citations

Jessica C. Stark, George E Marti, Nicholas M. Riley, Hongjuan Zhao, Carolyn R. Bertozzi +3 more

Supplementary Data from Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4–pRB Axis in Fibroblasts at the Invasive Tumor Edge

(2023)10.1158/0008-5472.22431249

Top 100%

0DataRank

Top 100%0 citations

Fernando Jose Garcia-Marques, Loukia Georgiou Karacosta, Weiruo Zhang, Abel Bermudez, Nicholas M. Riley +9 more

Comprehensive Overview of Bottom-Up Proteomics Using Mass Spectrometry

ACS Measurement Science Au(2024)10.1021/acsmeasuresciau.3c00068

N/A

0DataRank · unranked

170 citations

Devasahayam Arokia Balaya Rex, Dina Schuster, Benjamin A. Neely, Germán L. Rosano, Norbert Volkmar +15 more

Sialylated glycoproteins suppress immune cell killing by binding to Siglec-7 and Siglec-9 in prostate cancer

Journal of Clinical Investigation(2024)10.1172/jci180282

N/A

0DataRank · unranked

49 citations

Jessica C. Stark, G. Edward Marti, Zenghua Fan, Aram Lyu, Fernando Jose Garcia Marques +12 more

“Comparative Analysis of Glycoproteomic Software Using a Tailored Glycan Database”

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.24.604997

N/A

0DataRank · unranked

5 citations

Lauren E. Pepi, Nicholas M. Riley, Robert J. Chalkley, Reuben A. Hogan

Instrumentation at the leading edge of proteomics

ChemRxiv(2024)10.26434/chemrxiv-2023-8l72m-v2

N/A

0DataRank · unranked

2 citations

Joshua J. Coon, Nicholas M. Riley, Trenton M. Peters-Clarke

Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.06.627246

N/A

0DataRank · unranked

1 citations

Gianluca Interlandi, Tim S. Veth, Pavel Aprikian, Anna Manchenko, Veronika Tchesnokova +8 more

Revisiting the effect of trypsin digestion buffers on artificial deamidation

ChemRxiv(2024)10.26434/chemrxiv-2024-g66d2-v2

N/A

0DataRank · unranked

1 citations

Tim S. Veth, Nicholas M. Riley, Emmajay Sutherland

Autonomous Dissociation-type Selection for Glycoproteomics using a Real-Time Library Search

ChemRxiv(2024)10.26434/chemrxiv-2024-qdbrr

N/A

0DataRank · unranked

0 citations

Tim S. Veth, William D. Barshop, Jacob H. Russell, Kathryn Kothlow, Jesse D. Canterbury +8 more

Comparative analysis of glycoproteomic software using a tailored glycan database

Analytical and Bioanalytical Chemistry(2025)10.1007/s00216-025-05780-9

N/A

0DataRank · unranked

15 citations

Lauren E. Pepi, Nicholas M. Riley, Robert J. Chalkley, Reuben A. Hogan

Extracting Informative Glycan-Specific Ions From Glycopeptide MS/MS Spectra With GlyCounter

Molecular & Cellular Proteomics(2025)10.1016/j.mcpro.2025.101085

N/A

0DataRank · unranked

6 citations

Haley M. Schramm, Kayla A. Markuson, Jacob H. Russell, Emmajay Sutherland, Tim S. Veth +7 more

Accelerating the stride toward functional glycoproteomics

Trends in Biochemical Sciences(2025)10.1016/j.tibs.2025.04.002

N/A

0DataRank · unranked

3 citations

Nicholas M. Riley, Tim S. Veth

Sharing a Hybrid Electronic Health Record + Fast Healthcare Interoperability Resources Clinical Decision Support across Health Systems: Automating Smoking Cessation for Pediatric Caregivers

Applied Clinical Informatics(2025)10.1055/a-2535-5823

N/A

0DataRank · unranked

1 citations

Eric H. Kim, Jeritt G. Thayer, Emara Nabi-Burza, Dean Karavite, Jonathan P. Winickoff +5 more

Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference

Nature Communications(2025)10.1038/s41467-025-65666-3

N/A

0DataRank · unranked

0 citations

Gianluca Interlandi, Tim S. Veth, Pavel Aprikian, Anna A. Manchenko, Veronika Tchesnokova +8 more

Lysosome-targeting chimaeras for degradation of extracellular proteins

Nature(2020)10.1038/s41586-020-2545-9

N/A

0DataRank · unranked

1119 citations

Kayvon Pedram, Simon Wisnovsky, Green Ahn, Nicholas M. Riley, Carolyn R. Bertozzi +1 more

Sialoglycans on human T cells attenuate death programs executed through the Fas pathway

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.111047

N/A

0DataRank · unranked

0 citations

Qianmeng Lei, Tim S. Veth, Emmajay Sutherland, Hani Choksi, Fauzia Nurul Izzati +5 more

Cell type-selective secretome profiling in vivo

Nature Chemical Biology(2020)10.1038/s41589-020-00698-y

N/A

0DataRank · unranked

148 citations

Nicholas M. Riley, Andrew C. Yang, Joon T. Kim, Stephanie M. Terrell, Veronica L. Li +4 more

Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1917947117

N/A

0DataRank · unranked

85 citations

Gary M. Wilson, Lisa L. Kirkemo, Nicholas M. Riley, Joshua J. Coon, James A. Wells +1 more

Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis

Analytical Chemistry(2020)10.1021/acs.analchem.0c02950

N/A

0DataRank · unranked

58 citations

Stacy A. Malaker, Carolyn R. Bertozzi, Nicholas M. Riley

Lysosome Targeting Chimeras (LYTACs) That Engage a Liver-Specific Asialoglycoprotein Receptor for Targeted Protein Degradation

ChemRxiv(2020)10.26434/chemrxiv.12736778.v1

N/A

0DataRank · unranked

13 citations

Steven M. Banik, Caitlyn L. Miller, Nicholas M. Riley, Jennifer R. Cochran, Carolyn R. Bertozzi +1 more

O-Pair Search with MetaMorpheus for O-glycopeptide Characterization

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.18.102327

N/A

0DataRank · unranked

7 citations

Nicholas M. Riley, Michael R. Shortreed, Carolyn R. Bertozzi, Lloyd M. Smith, Lei Lü

Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19

ChemRxiv(2020)10.26434/chemrxiv.13378148

N/A

0DataRank · unranked

6 citations

Aaron J. Wilk, Nicholas M. Riley, Jessica C. Stark, Samuel Yang, Angela J. Rogers +5 more

Cell type-selective secretome profiling in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.18.303909

N/A

0DataRank · unranked

4 citations

Nicholas M. Riley, Andrew C. Yang, Joon T. Kim, Stephanie M. Terrell, Veronica L. Li +4 more

Nicholas M. Riley

Indexed papers

Top data-sharing exemplar

Papers