Jared E. Toettcher

Agricultural and Biological SciencesBiochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 38 papers. Top paper: “Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag”.

Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag

Nature Communications(2024)10.1038/s41467-024-50858-0

N/A

0.852DataRank · unranked

30 citations

Yang Gao, Kazuhiro Aoki, Jared E. Toettcher, Ellen H. Brumbaugh-Reed

Roadmap on biology in time varying environments

Physical Biology(2021)10.1088/1478-3975/abde8d

N/A

0.561DataRank · unranked

41 citations

Kabir Husain, Michael J. Rust, Chelsea Hepler, Joseph Bass, Julian MJ Pietsch +16 more

Development of light-responsive protein binding in the monobody non-immunoglobulin scaffold

Nature Communications(2020)10.1038/s41467-020-17837-7

N/A

0DataRank · unranked

59 citations

Evan M. Zhao, Agnieszka A. Gil, Nathan Alam, Jared E. Toettcher, José L. Avalos‬ +1 more

Design and Characterization of Rapid Optogenetic Circuits for Dynamic Control in Yeast Metabolic Engineering

ACS Synthetic Biology(2020)10.1021/acssynbio.0c00305

N/A

0DataRank · unranked

53 citations

Makoto A. Lalwani, Robert J. Lovelett, Sergio A. García-Echauri, Shannon M. Hoffman, Christopher L. Gonzalez +4 more

Engineering combinatorial and dynamic decoders using synthetic immediate-early genes

Communications Biology(2020)10.1038/s42003-020-01171-1

N/A

0DataRank · unranked

14 citations

Maxwell Z. Wilson, Siddhartha G. Jena, Jared E. Toettcher, Pavithran T. Ravindran

Optogenetic Rescue of a Patterning Mutant

Current Biology(2020)10.1016/j.cub.2020.06.059

N/A

0DataRank · unranked

44 citations

Nareg J.-V. Djabrayan, Stanislav Y. Shvartsman, Jared E. Toettcher, Heath E. Johnson

Light-responsive monobodies for dynamic control of customizable protein binding

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.08.831909

N/A

0DataRank · unranked

3 citations

Evan M. Zhao, Agnieszka A. Gil, Nathan Alam, Jared E. Toettcher, José L. Avalos‬ +1 more

Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the Jα Helix

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.29.925040

N/A

0DataRank · unranked

2 citations

Jinnette Tolentino Collado, Agnieszka A. Gil, Pavithran T. Ravindran, András Lukács, SeungYoun Shin +16 more

Optogenetic Amplification Circuits for Light-Induced Metabolic Control

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.23.424152

N/A

0DataRank · unranked

2 citations

Makoto A. Lalwani, Jhong‐Min Chen, Paulina Orillac, Jared E. Toettcher, José L. Avalos‬ +1 more

Clustering-based positive feedback between a kinase and its substrate enables effective T-cell receptor signaling

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.06.328708

N/A

0DataRank · unranked

0 citations

Ellen H. Reed, Jared E. Toettcher, Elliot Dine

Substratum stiffness regulates Erk signaling dynamics through receptor-level control

Cell Reports(2021)10.1016/j.celrep.2021.110181

N/A

0DataRank · unranked

55 citations

Sandra B. Lemke, Elliot Dine, Giselle A. Uribe, Jared E. Toettcher, Celeste M. Nelson +1 more

Signaling, Deconstructed: Using Optogenetics to Dissect and Direct Information Flow in Biological Systems

Annual Review of Biomedical Engineering(2021)10.1146/annurev-bioeng-083120-111648

N/A

0DataRank · unranked

48 citations

Ellen H. Reed, Evan J. Underhill, Kazuhiro Aoki, Jared E. Toettcher, Payam E. Farahani

A synthetic gene circuit for imaging-free detection of signaling pulses

Cell Systems(2021)10.1016/j.cels.2021.10.002

N/A

0DataRank · unranked

28 citations

Sarah McFann, Richard H. Thornton, Jared E. Toettcher, Pavithran T. Ravindran

Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch

Cell Reports(2021)10.1016/j.celrep.2021.109280

N/A

0DataRank · unranked

22 citations

Ellen H. Reed, Jared E. Toettcher, Elliot Dine

Dynamical Modeling of Optogenetic Circuits in Yeast for Metabolic Engineering Applications

ACS Synthetic Biology(2021)10.1021/acssynbio.0c00372

N/A

0DataRank · unranked

14 citations

Evan M. Zhao, Makoto A. Lalwani, Jared E. Toettcher, Ioannis G. Kevrekidis, José L. Avalos‬ +1 more

A self-exciting point process to study multicellular spatial signaling patterns

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2026123118

N/A

0DataRank · unranked

9 citations

Siddhartha G. Jena, Danielle R. Isakov, Kazuhiro Aoki, Jared E. Toettcher, Barbara E. Engelhardt +1 more

Dynamics and heterogeneity of Erk-induced immediate-early gene expression

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.30.442166

N/A

0DataRank · unranked

6 citations

Catherine Yu, Jared E. Toettcher, Siddhartha G. Jena

Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.13.464280

N/A

0DataRank · unranked

2 citations

Ping Wu, Sergey Ryabichko, João Raimundo, M.K. Swan, Eric Wieschaus +3 more

Synthetic developmental biology: New tools to deconstruct and rebuild developmental systems

Seminars in Cell and Developmental Biology(2022)10.1016/j.semcdb.2022.04.013

N/A

0DataRank · unranked

34 citations

Beatrice Ramm, Jared E. Toettcher, Harold M. McNamara

pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.13.503850

N/A

0DataRank · unranked

0 citations

Xiaoyu Yang, Emily V. Mesev, Kaylan A Fomby, Caleb J. Bashor, Celeste M. Nelson +2 more

Light-switchable transcription factors obtained by direct screening in mammalian cells

Nature Communications(2023)10.1038/s41467-023-38993-6

N/A

0DataRank · unranked

33 citations

Harold M. McNamara, Jared E. Toettcher, Liyuan Zhu

pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells

eLife(2023)10.7554/elife.82863

N/A

0DataRank · unranked

19 citations

Xiaoyu Yang, Emily V. Mesev, Kaylan A Fomby, Ellen H. Brumbaugh-Reed, Caleb J. Bashor +3 more

Membrane-proximal motifs encode differences in signaling strength between type I and III interferon receptors

Science Signaling(2023)10.1126/scisignal.adf5494

N/A

0DataRank · unranked

13 citations

Aaron E. Lin, Emma G. Guare, Brigitte Heller, Florian Douam, Britt Adamson +3 more

Dynamics of an incoherent feedforward loop drive ERK-dependent pattern formation in the early Drosophila embryo

Development(2023)10.1242/dev.201818

N/A

0DataRank · unranked

10 citations

Harrison R. Oatman, Sarah McFann, Liu Yang, Heath E. Johnson, Stanislav Y. Shvartsman +2 more

Dynamics of an incoherent feedforward loop drive ERK-dependent pattern formation in the early Drosophila embryo

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.09.531972

N/A

0DataRank · unranked

0 citations

Harrison R. Oatman, Sarah McFann, Liu Yang, Heath E. Johnson, Stanislav Y. Shvartsman +2 more

Recording morphogen signals reveals mechanisms underlying gastruloid symmetry breaking

Nature Cell Biology(2024)10.1038/s41556-024-01521-9

N/A

0DataRank · unranked

59 citations

Sabrina C. Solley, Britt Adamson, Michelle M. Chan, Jared E. Toettcher, Harold M. McNamara

Efficient prime editing in two-cell mouse embryos using PEmbryo

Nature Biotechnology(2024)10.1038/s41587-023-02106-x

N/A

0DataRank · unranked

25 citations

Ryan McNulty, Bradley Joyce, Antonio Mollica, Peter J. Chen, Purnima Ravisankar +7 more

Engineered chimeric receptors for dissecting interferon signaling

Journal of Virology(2024)10.1128/jvi.01680-23

N/A

0DataRank · unranked

3 citations

Emily V. Mesev, Jared E. Toettcher, Alexander Ploß, Aaron E. Lin

Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.16.575860

N/A

0DataRank · unranked

5 citations

Kazuhiro Aoki, Jared E. Toettcher, Ellen H. Brumbaugh-Reed

Large-scale control over collective cell migration using light-controlled epidermal growth factor receptors

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.30.596676

N/A

0DataRank · unranked

3 citations

Richard H. Thornton, Payam E. Farahani, Daniel J. Cohen, Jared E. Toettcher, Kevin Suh

Live imaging endogenous transcription factor dynamics reveals mechanisms of epiblast and primitive endoderm fate segregation

Current Biology(2025)10.1016/j.cub.2025.07.031

N/A

0DataRank · unranked

7 citations

David Denberg, Denis F. Faerberg, Hayden Nunley, Isabella Leite, Madeleine Chalifoux +5 more

A live-cell biosensor of in vivo receptor tyrosine kinase activity reveals feedback regulation of a developmental gradient

Cell Reports(2025)10.1016/j.celrep.2025.115930

N/A

0DataRank · unranked

3 citations

Rebecca Kim, Alison G. Simpkins, Payam E. Farahani, Harrison R. Oatman, Eszter Pósfai +3 more

CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb-based migration

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2024.12.31.630838

N/A

0DataRank · unranked

4 citations

Ankit Chandra, Payam E. Farahani, Jared E. Toettcher, Jason M. Haugh, Clare M. Waterman +1 more

PyCLM: programming-free, closed-loop microscopy for real-time measurement, segmentation, and optogenetic stimulation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.29.673155

N/A

0DataRank · unranked

3 citations

Beena C Lad, Jared E. Toettcher, Harrison R. Oatman

Design and optimization of a kinase-controlled allosteric switch

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.15.648940

N/A

0DataRank · unranked

2 citations

Jared E. Toettcher, Qi Cao

Optogenetic control of protein binding using light-switchable nanobodies

Nature Communications(2020)10.1038/s41467-020-17836-8

N/A

0DataRank · unranked

157 citations

César Carrasco‐López, Liyuan Zhu, Evan M. Zhao, Pavithran T. Ravindran, Maxwell Z. Wilson +4 more

Multimodal control of Cas13 activity through domain insertion at an allosteric hotspot

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.21.649818

N/A

0DataRank · unranked

0 citations

Long Thành Nguyễn, Alexandra G. Bell, Kara M Gillmann, Harrison R. Oatman, Jack Hariri +3 more

A Live-Cell Screen for Altered Erk Dynamics Reveals Principles of Proliferative Control

Cell Systems(2020)10.1016/j.cels.2020.02.005

N/A

0DataRank · unranked

94 citations

Maxwell Z. Wilson, Siddhartha G. Jena, Jillian Silbert, Lena P. Basta, Danelle Devenport +2 more