Tao Che

Also affiliated with Southern Medical University

Biochemistry, Genetics and Molecular BiologyNeuroscienceChemistryComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 27 papers. Top paper: “Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor”.

Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor

Cell(2020)10.1016/j.cell.2020.08.024

N/A

0.932DataRank · unranked

497 citations

Tao Che, Ouliana Panova, Jeffrey F. DiBerto, Jiankun Lyu, B. Krumm +8 more

Ligand efficacy modulates conformational dynamics of the µ-opioid receptor

Nature(2024)10.1038/s41586-024-07295-2

N/A

0.650DataRank · unranked

75 citations

Matthias Elgeti, Evan S. O’Brien, Cecı́lia P. Sár, Amal EI Daibani, Jie Heng +7 more

Docking for EP4R antagonists active against inflammatory pain

Nature Communications(2023)10.1038/s41467-023-43506-6

N/A

0.564DataRank · unranked

42 citations

Chelsea DeLeon, João Braz, Veronica Craik, Hye Jin Kang, Xiaobo Wan +14 more

A novel mitragynine analog with low efficacy mu-opioid receptor agonism displays antinociception with attenuated adverse effects

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.22.440994

N/A

0.292DataRank · unranked

6 citations

Jeffrey F. DiBerto, Abdelfattah Faouzi, Sarah M. Bernhard, Anna M. Gutridge, Steven Ramsey +19 more

A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c01273

N/A

0DataRank · unranked

75 citations

Jeffrey F. DiBerto, Abdelfattah Faouzi, Sarah M. Bernhard, Anna M. Gutridge, Steven Ramsey +19 more

Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site

eLife(2021)10.7554/elife.56519

N/A

0DataRank · unranked

66 citations

Tao Che, Saheem A. Zaidi, Steven G. Grinnell, Balázs R. Varga, Abdelfattah Faouzi +19 more

A promising chemical series of positive allosteric modulators of the μ-opioid receptor that enhance the antinociceptive efficacy of opioids but not their adverse effects

Neuropharmacology(2021)10.1016/j.neuropharm.2021.108673

N/A

0DataRank · unranked

34 citations

Hye Jin Kang, Farhana Sakloth, Yongfeng Liu, Susan Khan, Katalin Tóth +12 more

Structural insights into distinct signaling profiles of the μOR activated by diverse agonists

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.07.471645

N/A

0DataRank · unranked

6 citations

Weijiao Huang, Deniz Aydın, Joseph M. Paggi, Alpay B. Seven, Haoqing Wang +11 more

A Promising Chemical Series of Positive Allosteric Modulators of the μ-Opioid Receptor that Enhance the Antinociceptive Efficacy of Opioids but not their Adverse Effects

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.24.445057

N/A

0DataRank · unranked

0 citations

Hye Jin Kang, Farhana Sakloth, Yongfeng Liu, Susan Khan, Katalin Tóth +12 more

Structure-based design of bitopic ligands for the µ-opioid receptor

Nature(2022)10.1038/s41586-022-05588-y

N/A

0DataRank · unranked

128 citations

Haoqing Wang, Saheem A. Zaidi, Jeffrey F. DiBerto, Tao Che, Qianhui Qu +21 more

Molecular basis of opioid receptor signaling

Cell(2023)10.1016/j.cell.2023.10.029

N/A

0DataRank · unranked

117 citations

Bryan L. Roth, Tao Che

Molecular mechanism of biased signaling at the kappa opioid receptor

Nature Communications(2023)10.1038/s41467-023-37041-7

N/A

0DataRank · unranked

98 citations

Joseph M. Paggi, Kuglae Kim, Yianni Laloudakis, Petr Popov, Sarah M. Bernhard +9 more

Ligand and G-protein selectivity in the κ-opioid receptor

Nature(2023)10.1038/s41586-023-06030-7

N/A

0DataRank · unranked

79 citations

Jingying Zhang, Antonina L. Nazarova, Sarah M. Bernhard, B. Krumm, Lei Zhao +9 more

Direct Selection of DNA-Encoded Libraries for Biased Agonists of GPCRs on Live Cells

JACS Au(2023)10.1021/jacsau.2c00674

N/A

0DataRank · unranked

32 citations

Amal El Daibani, Yuntian Bai, Tao Che, Casey J. Krusemark, Bo Cai

GPCR‐G protein selectivity revealed by structural pharmacology

FEBS Journal(2023)10.1111/febs.17049

N/A

0DataRank · unranked

16 citations

Jianming Han, Tao Che, Sarah M. Bernhard

Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.28.538657

N/A

0DataRank · unranked

7 citations

Matthias Elgeti, Evan S. O’Brien, Cecı́lia P. Sár, Amal EI Daibani, Jie Heng +6 more

Liver ACOX1 regulates levels of circulating lipids that promote metabolic health through adipose remodeling

Nature Communications(2024)10.1038/s41467-024-48471-2

N/A

0DataRank · unranked

74 citations

Anyuan He, Min Tan, Marguerite Mrad, Amal El Daibani, Donghua Hu +8 more

Limitations and potential of κOR biased agonists for pain and itch management

Neuropharmacology(2024)10.1016/j.neuropharm.2024.110061

N/A

0DataRank · unranked

13 citations

Manish K. Madasu, Ream Al‐Hasani, Tao Che, Amal El Daibani

Searching for Synthetic Opioid Rescue Agents: Identification of a Potent Opioid Agonist with Reduced Respiratory Depression

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00333

N/A

0DataRank · unranked

7 citations

Dan Luo, Kai Johnson, Emily D. Denehy, Judy C. Songrady, Jocelyn Martin +15 more

Structure-Guided Design of Partial Agonists at an Opioid Receptor

Research Square(2024)10.21203/rs.3.rs-4664764/v1

N/A

0DataRank · unranked

0 citations

Balázs R. Varga, Sarah M. Bernhard, Amal El Daibani, Saheem A. Zaidi, Jordy Homing Lam +12 more

Structure-guided design of partial agonists at an opioid receptor

Nature Communications(2025)10.1038/s41467-025-57734-5

N/A

0DataRank · unranked

14 citations

Sarah M. Bernhard, Amal El Daibani, Saheem A. Zaidi, Jordy Homing Lam, Jhoan Aguilar +16 more

Searching for Synthetic Opioid Rescue Agents. 2: Identification of an Ultra-Potent Synthetic Opioid Rescue Agent

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01108

N/A

0DataRank · unranked

1 citations

Edem K. Onyameh, Dan Luo, Joshua W. Powell, Riya Trivedi, Eric J. Woloshin +12 more

Nanobody-enabled monitoring of kappa opioid receptor states

Nature Communications(2020)10.1038/s41467-020-14889-7

N/A

0DataRank · unranked

139 citations

Justin G. English, B. Krumm, Kuglae Kim, Els Pardon, Reid H. J. Olsen +9 more

Docking for EP4R antagonists active against inflammatory pain

UNC Libraries(2025)10.17615/545v-9x45

N/A

0DataRank · unranked

0 citations

Chelsea DeLeon, Bryan L. Roth, Brian K. Shoichet, Christian B. Billesbølle, Stefan Gahbauer +14 more

TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome

Nature Chemical Biology(2020)10.1038/s41589-020-0535-8

N/A

0DataRank · unranked

579 citations

Jeffrey F. DiBerto, Justin G. English, Alexis M. Glaudin, B. Krumm, Samuel T. Slocum +6 more

Predicted Mode of Binding to and Allosteric Modulation of the μ-Opioid Receptor by Kratom’s Alkaloids with Reported Antinociception In Vivo

Biochemistry(2020)10.1021/acs.biochem.0c00658

N/A

0DataRank · unranked

35 citations

Steven Ramsey, Davide Provasi, Amal El Daibani, Kevin Appourchaux, Soumen Chakraborty +5 more

Biased ligands at opioid receptors: Current status and future directions

Science Signaling(2021)10.1126/scisignal.aav0320

N/A

0DataRank · unranked

114 citations

Hemlata Dwivedi‐Agnihotri, Arun K. Shukla, Bryan L. Roth, Tao Che