Natalie Saini

Also affiliated with MUSC Hollings Cancer Center

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

14.1Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

Papers

Driven by 24 papers — median percentile 93. Top paper: “The repertoire of mutational signatures in human cancer”.

The repertoire of mutational signatures in human cancer

Nature(2020)10.1038/s41586-020-1943-3

N/A

10.7DataRank · unranked

3715 citations

Jaegil Kim, Nicholas J. Haradhvala, Mi Ni Huang, Alvin Wei Tian Ng, Yang Wu +74 more

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

Genomic and evolutionary classification of lung cancer in never smokers

Nature Genetics(2021)10.1038/s41588-021-00920-0

N/A

5.4DataRank · unranked

248 citations

Philippe Joubert, Naser Ansari‐Pour, Zhao Wei, Phuc H. Hoang, Rachel Lokanga +56 more

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Nature(2020)10.1038/s41586-020-1965-x

Top 5%

4.6DataRank

Top 5%668 citations

Federico Abascal, Jeremiah A. Wala, Ofer Shapira, Grace Tiao, Henrik Hornshøj +1240 more

Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic

PLoS ONE(2020)10.1371/journal.pone.0237689

Top 9%

2.5DataRank

Top 9%66 citations

Thomas A. Randall, Natalie Saini, Jian‐Liang Li, Dmitry A. Gordenin, Leszek J. Klimczak

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

bioRxiv (Cold Spring Harbor Laboratory)(2017)10.1101/208330

Top 17%

1.2DataRank

Top 17%26 citations

Grace Tiao, Bin Zhu, Tobias Rausch, Francesc Muyas, Alan J. Robertson +108 more

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

PLOS Biology(2019)10.1371/journal.pbio.3000464

N/A

0.587DataRank · unranked

49 citations

Natalie Saini, Leszek J. Klimczak, Kin Chan, Ewa P. Malc, Piotr A. Mieczkowski +4 more

Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Communications Biology(2022)10.1038/s42003-022-03769-z

N/A

0.165DataRank · unranked

2 citations

Lars Feuerbach, Chen Hong, David Mas-Ponte, Randi Istrup Pedersen, PCAWG Drivers and Functional Interpretation Group +1255 more

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

UNC Libraries(2020)10.17615/zfcq-5j88

N/A

0DataRank · unranked

15 citations

Leszek J. Klimczak, Natalie Saini, David C. Fargo, Dmitry A. Gordenin, David J. Kwiatkowski +7 more

Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1922472117

N/A

0DataRank · unranked

32 citations

Lei S. Qi, Ke Zhang, Natalie Saini, Leszek J. Klimczak, Cynthia J. Sakofsky +4 more

Fragile DNA Motifs Trigger Mutagenesis at Distant Chromosomal Loci in Saccharomyces cerevisiae

UNC Libraries(2020)10.17615/qc0c-yw59

N/A

0DataRank · unranked

0 citations

Shilpa Choudhury, Ziwei Sheng, Natalie Saini, Yuri Nishida, Kirill S. Lobachev +2 more

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts

UNC Libraries(2020)10.17615/0byj-a360

N/A

0DataRank · unranked

0 citations

Ewa P. Malc, Leszek J. Klimczak, Yang‐Wuyue Liu, Dmitry A. Gordenin, Sara A. Grimm +12 more

Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower

Nature Communications(2022)10.1038/s41467-022-32343-8

N/A

0DataRank · unranked

0 citations

PCAWG Drivers and Functional Interpretation Working Group, Federico Abascal, Samirkumar B. Amin, Pratiti Bandopadhayay, Rameen Beroukhim +1242 more

UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin

PLoS Genetics(2021)10.1371/journal.pgen.1009302

N/A

0DataRank · unranked

56 citations

Camille K. Giacobone, Leszek J. Klimczak, Brian N. Papas, Adam Burkholder, Jian‐Liang Li +7 more

Acetaldehyde makes a distinct mutation signature in single-stranded DNA

Nucleic Acids Research(2022)10.1093/nar/gkac570

N/A

0DataRank · unranked

43 citations

Latarsha Porcher, Piotr A. Mieczkowski, Natalie Saini, Sriram Vijayraghavan

Hypermutation in single-stranded DNA

DNA repair(2020)10.1016/j.dnarep.2020.102868

N/A

0DataRank · unranked

54 citations

Dmitry A. Gordenin, Natalie Saini

Aldehyde-Associated Mutagenesis─Current State of Knowledge

Chemical Research in Toxicology(2023)10.1021/acs.chemrestox.3c00045

N/A

0DataRank · unranked

54 citations

Natalie Saini, Sriram Vijayraghavan

Glycidamide-induced hypermutation in yeast single-stranded DNA reveals a ubiquitous clock-like mutational motif in humans

Nucleic Acids Research(2023)10.1093/nar/gkad611

N/A

0DataRank · unranked

14 citations

Leszek J. Klimczak, Joan F. Sterling, Adam Burkholder, Marat D. Kazanov, Natalie Saini +3 more

Widespread mutagenesis and chromosomal instability shape somatic genomes in systemic sclerosis

Nature Communications(2024)10.1038/s41467-024-53332-z

N/A

0DataRank · unranked

12 citations

Thomas Blouin, James M. McCollum, Latarsha Porcher, François Virard, Jiří Zavadil +3 more

Multiple DNA repair pathways prevent acetaldehyde-induced mutagenesis in yeast

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.07.574575

N/A

0DataRank · unranked

6 citations

Sriram Vijayraghavan, James M. McCollum, Piotr A. Mieczkowski, Natalie Saini, Latarsha Porcher

Methylglyoxal mutagenizes single-stranded DNA via Rev1-associated slippage and mispairing

Nucleic Acids Research(2025)10.1093/nar/gkaf705

N/A

0DataRank · unranked

3 citations

Alessandra Ruggiero, Samuel Becker, Piotr A. Mieczkowski, George S. Hanna, Mark T. Hamann +2 more

Translesion polymerases and DNA–protein crosslink repair shapes the cellular response to formaldehyde-induced DNA damage in ssDNA

Nucleic Acids Research(2025)10.1093/nar/gkaf914

N/A

0DataRank · unranked

3 citations

Elizabeth A. Ampolini, Kristina Stayer, Parameshwar Suresh, Piotr A. Mieczkowski, Natalie Saini +1 more

Glycidamide-induced hypermutation in yeast single-stranded DNA reveals a ubiquitous clock-like mutational motif in humans

UNC Libraries(2025)10.17615/gzbt-8003

N/A

0DataRank · unranked

0 citations

Piotr A. Mieczkowski, Marat D. Kazanov, Natalie Saini, Leszek J. Klimczak, Joan F. Sterling +3 more

Acetaldehyde makes a distinct mutation signature in single-stranded DNA

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.22.485364

N/A

0DataRank · unranked

1 citations

Latarsha Porcher, Piotr A. Mieczkowski, Natalie Saini, Sriram Vijayraghavan

Natalie Saini

Indexed papers

Top data-sharing exemplar

Papers