J. Kent Leach

Also affiliated with University of California, Davis

MedicineEngineeringMaterials Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 41 papers. Top paper: “Growth factor delivery using extracellular matrix-mimicking substrates for musculoskeletal tissue engineering and repair”.

Growth factor delivery using extracellular matrix-mimicking substrates for musculoskeletal tissue engineering and repair

Bioactive Materials(2020)10.1016/j.bioactmat.2020.12.012

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111 citations

Chelsea S. Bahney, J. Kent Leach, Robert C.H. Gresham

Functionally Graded Biomaterials for Use as Model Systems and Replacement Tissues

Advanced Functional Materials(2020)10.1002/adfm.201909089

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103 citations

J. Kent Leach, Jeremy Lowen

Tunable fibrin-alginate interpenetrating network hydrogels to support cell spreading and network formation

Acta Biomaterialia(2020)10.1016/j.actbio.2020.03.014

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93 citations

Tomas Gonzalez‐Fernandez, Shreeya Joshee, Pawel Sikorski, J. Kent Leach, Charlotte E. Vorwald

Hydrogel mechanics are a key driver of bone formation by mesenchymal stromal cell spheroids

Biomaterials(2020)10.1016/j.biomaterials.2020.120607

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93 citations

Katherine H. Griffin, Marissa Gionet‐Gonzales, Charlotte E. Vorwald, Serena E. Cinque, J. Kent Leach +1 more

Multi-peptide presentation and hydrogel mechanics jointly enhance therapeutic duo-potential of entrapped stromal cells

Biomaterials(2020)10.1016/j.biomaterials.2020.119973

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47 citations

Tomas Gonzalez‐Fernandez, Jenny Lin, Takeyah Campbell, Yu Bin Lee, Alyssa Panitch +3 more

Tissue engineered platforms for studying primary and metastatic neoplasm behavior in bone

Journal of Biomechanics(2020)10.1016/j.jbiomech.2020.110189

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17 citations

Katherine H. Griffin, Steven W. Thorpe, R. Lor Randall, J. Kent Leach, Victoria L. Thai

Osteogenic preconditioning in perfusion bioreactors improves vascularization and bone formation by human bone marrow aspirates

Science Advances(2020)10.1126/sciadv.aay2387

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46 citations

Tomas Gonzalez‐Fernandez, Aimy Sebastian, Nicholas R. Hum, Damian C. Genetos, Gabriela G. Loots +2 more

Spatial localization of endothelial cells in heterotypic spheroids influences Notch signaling

Journal of Molecular Medicine(2020)10.1007/s00109-020-01883-1

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31 citations

Shreeya Joshee, J. Kent Leach, Charlotte E. Vorwald

Evaluation of Alginate-Based Bioinks for 3D Bioprinting, Mesenchymal Stromal Cell Osteogenesis, and Application for Patient-Specific Bone Grafts

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.09.242131

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9 citations

Alejandro J. Tenorio, Kevin T. Campbell, Eduardo A. Silva, J. Kent Leach, Tomas Gonzalez‐Fernandez

Hydrogel mechanical properties are more important than osteoinductive growth factors for bone formation with MSC spheroids

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.10.986315

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1 citations

Katherine H. Griffin, Charlotte E. Vorwald, Marissa Gionet‐Gonzales, Serena E. Cinque, J. Kent Leach +1 more

Engineered Cell‐Secreted Extracellular Matrix Modulates Cell Spheroid Mechanosensing and Amplifies Their Response to Inductive Cues for the Formation of Mineralized Tissues

Advanced Healthcare Materials(2021)10.1002/adhm.202102337

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69 citations

Alejandro J. Tenorio, Augustine M. Saiz, J. Kent Leach, Tomas Gonzalez‐Fernandez

Sulfated Alginate Hydrogels Prolong the Therapeutic Potential of MSC Spheroids by Sequestering the Secretome

Advanced Healthcare Materials(2021)10.1002/adhm.202101048

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50 citations

Alena Casella, Daphne A. Diloretto, Clara Ginnell, Katherine H. Griffin, Anne Bigot +2 more

Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling

npj Regenerative Medicine(2022)10.1038/s41536-022-00266-z

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110 citations

Shierly W. Fok, J. Kent Leach, Katherine H. Griffin

Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair

Theranostics(2022)10.7150/thno.70448

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48 citations

Lu Lu, Hengyue Song, Yixin Duan, Jianing Chen, Randy P. Carney +9 more

Mesenchymal stromal cell spheroids in sulfated alginate enhance muscle regeneration

Acta Biomaterialia(2022)10.1016/j.actbio.2022.10.054

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23 citations

Robert C.H. Gresham, Katherine H. Griffin, Alena Casella, Ross P. Wohlgemuth, David H. Ramos‐Rodriguez +4 more

Non-destructive, continuous monitoring of biochemical, mechanical, and structural maturation in engineered tissue

Scientific Reports(2022)10.1038/s41598-022-18702-x

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14 citations

Benjamin E. Sherlock, Xiangnan Zhou, Clay S. Sheaff, Jerry C. Hu, J. Kent Leach +3 more

Multisized Photoannealable Microgels Regulate Cell Spreading, Aggregation, and Macrophage Phenotype through Microporous Void Space

Advanced Healthcare Materials(2023)10.1002/adhm.202202239

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55 citations

Gabriella C. Bond, Katherine H. Griffin, Nathan Shimamoto, Victoria L. Thai, J. Kent Leach +1 more

Hydrogel degradation promotes angiogenic and regenerative potential of cell spheroids for wound healing

Materials Today Bio(2023)10.1016/j.mtbio.2023.100769

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45 citations

David H. Ramos‐Rodriguez, Meron Mesfin, J. Kent Leach, Victoria L. Thai

Skeletal Muscle Spheroids as Building Blocks for Engineered Muscle Tissue

ACS Biomaterials Science & Engineering(2023)10.1021/acsbiomaterials.3c01078

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22 citations

Andrea C. Filler, Akash Sethi, Lucas Smith, J. Kent Leach, N.F. Johnson

Prostate cancer and bone: clinical presentation and molecular mechanisms

Endocrine Related Cancer(2023)10.1530/erc-22-0360

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14 citations

Margaret Li Krackeler, Maitreyee K. Jathal, Mamta Parikh, P. Ghosh, J. Kent Leach +2 more

Conductive Microgel Annealed Scaffolds Enhance Myogenic Potential of Myoblastic Cells

Advanced Healthcare Materials(2023)10.1002/adhm.202302500

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11 citations

Jeremy Lowen, Katherine H. Griffin, Nathan Shimamoto, David H. Ramos‐Rodriguez, Alyssa Panitch +2 more

Macromolecular crowding and decellularization method increase the growth factor binding potential of cell-secreted extracellular matrices

Frontiers in Bioengineering and Biotechnology(2023)10.3389/fbioe.2023.1091157

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19 citations

Robert C.H. Gresham, Weston Ryan, Benjamin Osipov, Chelsea S. Bahney, J. Kent Leach +1 more

Engineered bone marrow as a clinically relevant ex vivo model for primary bone cancer research and drug screening

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2302101120

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14 citations

Steven W. Thorpe, Aimy Sebastian, Nicholas R. Hum, Thomas P. Coonan, Isabel S. Sagheb +4 more

Compliant substrates mitigate the senescence associated phenotype of stress induced mesenchymal stromal cells

Journal of Biomedical Materials Research Part A(2023)10.1002/jbm.a.37657

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13 citations

Andrea C. Filler, Shierly W. Fok, Molly Czachor, Natalie Schmier, Claire Pearson +3 more

Electroconductive agarose hydrogels modulate mesenchymal stromal cell adhesion and spreading through protein adsorption

Journal of Biomedical Materials Research Part A(2023)10.1002/jbm.a.37503

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13 citations

Alyssa Panitch, J. Kent Leach, Alena Casella

Biomaterials are the key to unlock spheroid function and therapeutic potential

Biomaterials and Biosystems(2023)10.1016/j.bbiosy.2023.100080

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4 citations

J. Kent Leach, David H. Ramos‐Rodriguez

Conductive microgel annealed scaffolds enhance myogenic potential of myoblastic cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.01.551533

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0 citations

Jeremy Lowen, Nathan Shimamoto, Katherine H. Griffin, Andrea C. Filler, Alyssa Panitch +2 more

Decellularized Cell‐Secreted Extracellular Matrices as Biomaterials for Tissue Engineering

Small Science(2024)10.1002/smsc.202400335

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24 citations

J. Kent Leach, David H. Ramos‐Rodriguez

Functionalized Annealed Microgels for Spatial Control of Osteogenic and Chondrogenic Differentiation

Advanced Functional Materials(2024)10.1002/adfm.202311017

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18 citations

Erika E. Wheeler, Nathan Shimamoto, David H. Ramos‐Rodriguez, Katherine H. Griffin, Gabriella C. Bond +2 more

Polytrauma impairs fracture healing accompanied by increased persistence of innate inflammatory stimuli and reduced adaptive response

Journal of Orthopaedic Research®(2024)10.1002/jor.26015

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12 citations

Maryam Rahmati, Robert C.H. Gresham, Tony Daniel Baldini, Jane Burgan, Mark Lee +11 more

Mechanoregulation of MSC spheroid immunomodulation

APL Bioengineering(2024)10.1063/5.0184431

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12 citations

Sabrina Mierswa, Katherine H. Griffin, Joel D. Boerckel, J. Kent Leach, Victoria L. Thai

Extracellular Vesicles from Highly Metastatic Osteosarcoma Cells Induce Pro‐Tumorigenic Macrophage Phenotypes

Advanced Biology(2024)10.1002/adbi.202300577

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11 citations

Rachel R. Mizenko, Vishalakshi Arun, Randy P. Carney, J. Kent Leach, Katherine H. Griffin

Biofabrication of engineered tissues by 3D bioprinting of tissue specific high cell-density bioinks

Materials Today(2025)10.1016/j.mattod.2025.03.021

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7 citations

Hyoeun Park, J. Kent Leach, Eben Alsberg, Oju Jeon

High-Resolution Atomic Force Microscopy Investigation of Alginate Hydrogel Materials in Aqueous Media

Langmuir(2024)10.1021/acs.langmuir.4c03554

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4 citations

Ümit Çelik, Charlotte E. Vorwald, J. Kent Leach, Gang-yu Liu, Yunbo Zheng

Neutrophil Granulopoiesis Optimized Through Ex Vivo Expansion of Hematopoietic Progenitors in Engineered 3D Gelatin Methacrylate Hydrogels

Advanced Healthcare Materials(2024)10.1002/adhm.202301966

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6 citations

Alex Vargas, Erika E. Wheeler, J. Kent Leach, Scott I. Simon, Tomas Gonzalez‐Fernandez +1 more

Human skeletal development and regeneration are shaped by functional diversity of stem cells across skeletal sites

Cell stem cell(2025)10.1016/j.stem.2025.02.013

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18 citations

Sahar Taheri, Kun Chen, Rahul Sinha, Yuting Wang, Ethan J. Hunt +30 more

Mesenchymal Stromal Cell Chondrogenic Differentiation Induced by Continuous Stiffness Gradient in Photocrosslinkable Hydrogels

Journal of Biomedical Materials Research Part A(2025)10.1002/jbm.a.37928

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7 citations

Erika E. Wheeler, Ayla N. Apsey, Oju Jeon, Eben Alsberg, J. Kent Leach +1 more

Basigin links altered skeletal stem cell lineage dynamics with glucocorticoid-induced bone loss and impaired angiogenesis

Nature Communications(2025)10.1038/s41467-025-62881-w

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2 citations

David L.S. Morales, Kun Chen, Eleanor A. Hunt, Kelly C. Weldon, Amber N Maifeld +13 more

Systemic versus local delivery of mesenchymal stem cells to improve the early stages of fracture healing in a polytrauma model

Journal of Biological Engineering(2025)10.1186/s13036-025-00554-4

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3 citations

Maryam Rahmati, Sadie Johnson, Aneesh Satish Bhat, Tony Daniel Baldini, Øystein Øvrebø +8 more

Zwitterionic Microgel Scaffolds Support Matrix Accumulation by Regulating Protein Adsorption

Advanced Healthcare Materials(2025)10.1002/adhm.202503483

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1 citations

Ayla N. Apsey, J. Kent Leach, Erika E. Wheeler

Controlled delivery of immunomodulatory factors for mineralized tissue formation in an inflammatory microenvironment

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.21.655332

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0 citations

Isabel S. Sagheb, Thomas P. Coonan, Lanyan Wu, Douglas J. Rowland, Boaz Arzi +3 more