🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Edward L. Huttlin

Harvard University

ORCID: 0000-0002-1822-1173
ChemistryBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile
10.8Author DataRank

Indexed papers

6in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 6 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.19.905109
Top 6%
3.7DataRank
Top 6%121 citations

Raphael J. Bruckner, José Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab +21 more

Papers

Driven by 16 papers — median percentile 81. Top paper: “Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome”.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.19.905109
Top 6%
3.7DataRank
Top 6%121 citations

Raphael J. Bruckner, José Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab +21 more

A proteome-wide atlas of drug mechanism of action

Nature Biotechnology(2023)10.1038/s41587-022-01539-0
Top 7%
3.4DataRank
Top 7%148 citations

Miljan Kuljanin, Jiaming Li, Jonathan G. Van Vranken, Nathan J. Bulloch, Devin K. Schweppe +3 more

A multi-scale map of cell structure fusing protein images and interactions

Nature(2021)10.1038/s41586-021-04115-9
Top 9%
2.3DataRank
Top 9%80 citations

Edward L. Huttlin, Casper Winsnes, Maya L. Gosztyla, Ludivine Wacheul, Marcus R. Kelly +23 more

Multimodal cell maps as a foundation for structural and functional genomics

Nature(2025)10.1038/s41586-025-08878-3
Top 29%
0.697DataRank
Top 29%36 citations

Mengzhou Hu, Gege Qian, Kyung‐Mee Moon, Abantika Pal, Neelesh Soni +29 more

BioPlexR and BioPlexPy: integrated data products for the analysis of human protein interactions

Bioinformatics(2023)10.1093/bioinformatics/btad091
Top 45%
0.405DataRank
Top 45%8 citations

Roger Vargas, Tyrone Lee, Joshua Pan, Edward L. Huttlin, Robert Gentleman +1 more

Mapping cell structure across scales by fusing protein images and interactions

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.21.163709
Top 49%
0.365DataRank
Top 49%7 citations

Casper Winsnes, Edward L. Huttlin, Fan Zheng, Wei Ouyang, Jisoo Park +8 more

Architecture of the outbred brown fat proteome defines regulators of metabolic physiology

Cell(2022)10.1016/j.cell.2022.10.003
N/A
0DataRank · unranked
39 citations

Luiz H. M. Bozi, Yizhi Sun, Christopher L. Riley, Vivek M. Philip, Mandy Chen +41 more

Selection of Heating Temperatures Improves the Sensitivity of the Proteome Integral Solubility Alteration Assay

Journal of Proteome Research(2020)10.1021/acs.jproteome.0c00063
N/A
0DataRank · unranked
62 citations

Jonathan G. Van Vranken, Joao A. Paulo, Edward L. Huttlin, Steven P. Gygi, Jiaming Li

An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation

Molecular Cell(2023)10.1016/j.molcel.2023.05.018
N/A
0DataRank · unranked
64 citations

Cassie Zerbe, David Vanderwall, Edward L. Huttlin, Michael P. Weekes, Benjamin E. Gewurz +1 more

Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression

Nature Communications(2023)10.1038/s41467-023-36269-7
N/A
0DataRank · unranked
35 citations

Xinyue Liu, Mark P. Keller, José Navarrete-Perea, Tian Zhang, Sipei Fu +14 more

Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection

Nature Communications(2023)10.1038/s41467-023-43299-8
N/A
0DataRank · unranked
10 citations

Joanne Kite, Marisa Oliveira, Hanqi Li, Ying Di, Maria H. Christensen +8 more

Human Polo-like Kinase Inhibitors as Antiplasmodials

ACS Infectious Diseases(2023)10.1021/acsinfecdis.3c00025
N/A
0DataRank · unranked
8 citations

Jinhua Wang, Eva S. Istvan, Madeline R. Luth, Jennifer E. Collins, Edward L. Huttlin +12 more

Profiling Proteins and Phosphorylation Sites During T Cell Activation Using an Integrated Thermal Shift Assay

Molecular & Cellular Proteomics(2024)10.1016/j.mcpro.2024.100801
N/A
0DataRank · unranked
5 citations

Edward L. Huttlin, Emily M. Huntsman, Tomer M. Yaron-Barir, Jared L. Johnson, Kiran Kurmi +6 more

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome

Cell(2021)10.1016/j.cell.2021.04.011
N/A
0DataRank · unranked
1006 citations

Raphael J. Bruckner, José Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab +23 more

A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging

Cell(2020)10.1016/j.cell.2020.02.012
N/A
0DataRank · unranked
420 citations

Mark P. Jedrychowski, Devin K. Schweppe, Edward L. Huttlin, Qing Yu, David E. Heppner +15 more

Proteome-wide mapping of short-lived proteins in human cells

Molecular Cell(2021)10.1016/j.molcel.2021.09.015
N/A
0DataRank · unranked
179 citations

Zhenying Cai, Laura Pontano Vaites, Ning Shen, Dylan C. Mitchell, Edward L. Huttlin +4 more