Kai W. Wucherpfennig

Also affiliated with Harvard University, Dana-Farber Cancer Institute, Dana-Farber/Harvard Cancer Center, Dana-Farber Brigham Cancer Center

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 53 papers. Top paper: “Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion”.

Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion

Nature Genetics(2021)10.1038/s41588-021-00779-1

N/A

6.5DataRank · unranked

271 citations

Johannes C. Melms, Pratiksha I. Thakore, Kathryn Geiger-Schuller, Patricia Ho, Adrienne Luoma +17 more

Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma

Nature Medicine(2021)10.1038/s41591-020-01206-4

N/A

4.5DataRank · unranked

525 citations

Donna Leet, Rosa Lundbye Allesøe, Giacomo Oliveira, Shuqiang Li, Adrienne Luoma +36 more

Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma

Cancer Cell(2020)10.1016/j.ccell.2020.06.004

N/A

3.8DataRank · unranked

165 citations

Bernhard Englinger, Li Jiang, Jens M Hübner, Olivia A. Hack, Sibylle Madlener +38 more

Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma

Nature Medicine(2021)10.1038/s41591-020-01212-6

N/A

3.5DataRank · unranked

127 citations

Cyril Neftel, Marni E. Shore, Hannah R. Weisman, Nathan D. Mathewson, Matthew J. McBride +50 more

The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity

Cancer Cell(2023)10.1016/j.ccell.2023.05.014

N/A

1.8DataRank · unranked

96 citations

Johannes C. Melms, Meri Rogava, Chris J. Frangieh, Joanna Poźniak, Shivem B. Shah +28 more

Immunosuppressive Myeloid Cells Induce Nitric Oxide–Dependent DNA Damage and p53 Pathway Activation in CD8+ T Cells

Cancer Immunology Research(2021)10.1158/2326-6066.cir-20-0085

N/A

1.4DataRank · unranked

44 citations

Shengbao Suo, S Badrinath, Sushil Kumar, Johannes C. Melms, Adrienne Luoma +6 more

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

Nature(2018)10.1038/s41586-018-0792-9

N/A

1.1DataRank · unranked

1412 citations

Jing Sun, Itay Tirosh, Nathan D. Mathewson, Shuqiang Li, Giacomo Oliveira +51 more

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

Science(2018)10.1126/science.aao4750

N/A

0.989DataRank · unranked

728 citations

Itay Tirosh, Volker Hovestadt, Leah E. Escalante, Nathan D. Mathewson, Cyril Neftel +46 more

Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma

Cancer Cell(2021)10.1016/j.ccell.2021.05.002

N/A

0.953DataRank · unranked

575 citations

Rony Chanoch-Myers, Nathan D. Mathewson, Chad Myskiw, Lyla Atta, Lillian Bussema +17 more

Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy

Cell(2020)10.1016/j.cell.2020.06.001

N/A

0.927DataRank · unranked

481 citations

Shengbao Suo, Hannah L. Williams, Tatyana Sharova, Keri M. Sullivan, Michael P. Manos +11 more

Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis

Cell(2021)10.1016/j.cell.2021.01.022

N/A

0.897DataRank · unranked

394 citations

Orr Ashenberg, Itay Tirosh, Simon Gritsch, Elizabeth M. Perez, Sascha Marx +38 more

Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: potential for clinical application

Blood(2002)10.1182/blood.v99.9.3319

N/A

0.789DataRank · unranked

191 citations

Robert H. Vonderheide, Britta Maecker, Naoto Hirano, Karen S. Anderson, Marcus O. Butler +6 more

A vaccine targeting resistant tumours by dual T cell plus NK cell attack

Nature(2022)10.1038/s41586-022-04772-4

N/A

0.748DataRank · unranked

145 citations

Maxence O. Dellacherie, Aileen W. Li, Shiwei Zheng, Xixi Zhang, Miguel C. Sobral +12 more

Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity

Journal of Experimental Medicine(2018)10.1084/jem.20180300

N/A

0.489DataRank · unranked

25 citations

Orr Ashenberg, Jason Pyrdol, Adrienne M. Luoma, Matan Hofree, Elena Christian +10 more

First-in-human CAN-3110 (ICP-34.5 expressing HSV-1 oncolytic virus) in patients with recurrent high-grade glioma.

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.2009

N/A

0.419DataRank · unranked

7 citations

Isaac H. Solomon, Hiroshi Nakashima, Sean Lawler, Daniel Triggs, Abigail Zhang +15 more

Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.01.267211

N/A

0.375DataRank · unranked

5 citations

Johannes C. Melms, Pratiksha I. Thakore, Kathryn R. Geiger-Schuller, Patricia Ho, Adrienne Luoma +15 more

Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma

Cancer Cell(2025)10.1016/j.ccell.2025.05.007

N/A

0.110DataRank · unranked

1 citations

Rony Chanoch-Myers, Nathan D. Mathewson, Chad Myskiw, Lyla Atta, Lillian Bussema +17 more

Mechanical checkpoint regulates monocyte differentiation in fibrotic niches

Nature Materials(2022)10.1038/s41563-022-01293-3

N/A

0DataRank · unranked

87 citations

Anna E. Marneth, Kwasi Adu‐Berchie, Joshua M. Grolman, Christina M. Tringides, Yutong Liu +10 more

Cytokine conjugation to enhance T cell therapy

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2213222120

N/A

0DataRank · unranked

55 citations

Kwasi Adu‐Berchie, Joshua M. Brockman, Matthew J. Pezone, David Zhang, Jingyi Zhou +5 more

A Conceptual Framework for Inducing T Cell-Mediated Immunity Against Glioblastoma

Seminars in Immunopathology(2022)10.1007/s00281-022-00945-5

N/A

0DataRank · unranked

7 citations

Anže Godicelj, Kai W. Wucherpfennig, Sascha Marx

The CD58:CD2 axis is co-regulated with PD-L1 via CMTM6 and governs anti-tumor immunity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.21.485049

N/A

0DataRank · unranked

10 citations

Johannes C. Melms, Meri Rogava, Chris J. Frangieh, Shivem B. Shah, Zachary Walsh +21 more

Heterogeneity and transcriptional drivers of triple-negative breast cancer

Cell Reports(2023)10.1016/j.celrep.2023.113564

N/A

0DataRank · unranked

29 citations

Daniel Temko, Laura E. Stevens, Marco Seehawer, Anne Fassl, Katherine C. Murphy +33 more

A chimeric antigen receptor uniquely recognizing MICA/B stress proteins provides an effective approach to target solid tumors

Med(2023)10.1016/j.medj.2023.04.004

N/A

0DataRank · unranked

25 citations

Wen-I Yeh, Bryan Hancock, Robert Blum, Tianhao Xu, Bi-Huei Yang +22 more

Addressing Tumor Heterogeneity by Sensitizing Resistant Cancer Cells to T cell–Secreted Cytokines

Cancer Discovery(2023)10.1158/2159-8290.cd-22-1125

N/A

0DataRank · unranked

21 citations

Deng Pan, Wubing Zhang, Xixi Zhang, Tiffany Y. Juan, Jason W. Pyrdol +5 more

Targeting of the CD161 inhibitory receptor enhances T-cell–mediated immunity against hematological malignancies

Blood(2023)10.1182/blood.2023022882

N/A

0DataRank · unranked

21 citations

Byong H. Kang, Oleksandr Kyrysyuk, Shiwei Zheng, Hao Wang, Nathan D. Mathewson +9 more

Selective Mitochondrial Respiratory Complex I Subunit Deficiency Causes Tumor Immunogenicity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.02.560316

N/A

0DataRank · unranked

1 citations

Tevis Vitale, Xixi Zhang, Thomas D. Jackson, Deyang Yu, Mark P. Jedrychowski +5 more

Data from The Tumor Microenvironment Shapes Lineage, Transcriptional, and Functional Diversity of Infiltrating Myeloid Cells

(2023)10.1158/2326-6066.c.6548549.v1

N/A

0DataRank · unranked

0 citations

Viviana Cremasco, Hua Shen, Christopher J. Harvey, Kai W. Wucherpfennig, Daniel R. Goldstein +3 more

Data from FAP Delineates Heterogeneous and Functionally Divergent Stromal Cells in Immune-Excluded Breast Tumors

(2023)10.1158/2326-6066.c.6548938.v1

N/A

0DataRank · unranked

0 citations

Jillian L. Astarita, Angelo L. Grauel, Shilpa Keerthivasan, Kenzie D. Macisaac, Matthew C. Woodruff +15 more

Data from CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells

(2023)10.1158/2159-8290.c.6549178.v1

N/A

0DataRank · unranked

0 citations

Zexian Zeng, Archis Bagati, Rong En Tay, Lionel A. Sanz, Stella R. Hartono +17 more

Data from Immunosuppressive Myeloid Cells Induce Nitric Oxide–Dependent DNA Damage and p53 Pathway Activation in CD8+ T Cells

(2023)10.1158/2326-6066.c.6550204.v1

N/A

0DataRank · unranked

0 citations

Shengbao Suo, S Badrinath, Sushil Kumar, Johannes C. Melms, Adrienne Luoma +6 more

OTME-7. Cancer - immune cell interactions drive transitions to mesenchymal-like state in glioblastoma

Neuro-Oncology Advances(2021)10.1093/noajnl/vdab070.058

N/A

0DataRank · unranked

0 citations

Rony Chanoch-Myers, Chad Myskiw, Lyla Atta, Lillian Bussema, Gabriela S. Kinker +17 more

MICA-specific nanobodies for diagnosis and immunotherapy of MICA+ tumors

Frontiers in Immunology(2024)10.3389/fimmu.2024.1368586

N/A

0DataRank · unranked

13 citations

Anouk Knoflook, Novalia Pishesha, Xin Liu, Willemijn J. C. van Keizerswaard, Kai W. Wucherpfennig +2 more

Neoadjuvant immune checkpoint blockade enhances local and systemic tumor immunity in head and neck cancer

Current Opinion in Oncology(2024)10.1097/cco.0000000000001023

N/A

0DataRank · unranked

6 citations

Kai W. Wucherpfennig, Ye Zhao

CRATER tumor niches facilitate CD8+ T cell engagement and correspond with immunotherapy success

Cell(2025)10.1016/j.cell.2025.09.021

N/A

0DataRank · unranked

11 citations

Georgia L. Stirtz, Asaf Tal, Ajit J. Nirmal, Kathleen L. Pfaff, Michael P. Manos +39 more

Defective removal of invariant chain peptides from MHC class II suppresses tumor antigen presentation and promotes tumor growth

Cell Reports(2025)10.1016/j.celrep.2024.115150

N/A

0DataRank · unranked

9 citations

Yoshinaga Ito, Kai W. Wucherpfennig, Paul A. Roche, Joanna Bandola-Simon

Unlocking LAG3: Ubiquitin’s unexpected role

Cell(2025)10.1016/j.cell.2025.03.030

N/A

0DataRank · unranked

0 citations

Kai W. Wucherpfennig, Ye Zhao

Tissue-Resident T Cells in Clinical Response and Immune-Related Adverse Events of Immune Checkpoint Blockade

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-23-3296

N/A

0DataRank · unranked

17 citations

Kai W. Wucherpfennig, Ye Zhao

ATIM-32. PERSONALIZED NEOANTIGEN-TARGETING VACCINE GENERATES ROBUST SYSTEMIC AND INTRATUMORAL T CELL RESPONSES IN GLIOBLASTOMA (GBM) PATIENTS

Neuro-Oncology(2018)10.1093/neuonc/noy148.027

N/A

0DataRank · unranked

0 citations

Itay Tirosh, Annabelle Anandappa, Jing Sun, Chang‐Jiun Wu, Evisa Gjini +21 more

EPCO-35. SINGLE-CELL RNA-SEQ OF PEDIATRIC EPENDYMOMA REVEALS PROGNOSTIC IMPACT OF IMPAIRED NEURONAL-GLIAL FATE SPECIFICATION

Neuro-Oncology(2020)10.1093/neuonc/noaa215.314

N/A

0DataRank · unranked

0 citations

Johannes Gojo, Li Jiang, Jens M Hübner, McKenzie Shaw, Ilon Liu +38 more

OTME-8. Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis

Neuro-Oncology Advances(2021)10.1093/noajnl/vdab070.059

N/A

0DataRank · unranked

0 citations

Orr Ashenberg, Elizabeth Perez, Sascha Marx, Prisca Liberali, Nathan D. Mathewson +5 more

TAMI-12. CANCER-IMMUNE CELL INTERACTIONS DRIVE TRANSITIONS TO MESENCHYMAL-LIKE STATES IN GLIOBLASTOMA

Neuro-Oncology(2021)10.1093/neuonc/noab196.796

N/A

0DataRank · unranked

0 citations

Rony Chanoch-Myers, Chad Myskiw, Lyla Atta, Lillian Bussema, Alissa Greenwald +17 more

EPEN-21. IMPAIRED NEURONAL-GLIAL FATE SPECIFICATION IN PEDIATRIC EPENDYMOMA REVEALED BY SINGLE-CELL RNA-SEQ

Neuro-Oncology(2020)10.1093/neuonc/noaa222.158

N/A

0DataRank · unranked

0 citations

Johannes Gojo, Li Jiang, Jens M Hübner, Olivia A. Hack, Sibylle Madlener +35 more

Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

Cancer Cell(2020)10.1016/j.ccell.2020.12.001

N/A

0DataRank · unranked

211 citations

Sushil Kumar, Peng Jiang, Jason W. Pyrdol, Angela E. Zou, Anže Godicelj +11 more

Metabolic labeling and targeted modulation of dendritic cells

Nature Materials(2020)10.1038/s41563-020-0680-1

N/A

0DataRank · unranked

183 citations

Miguel C. Sobral, David Zhang, Adam N.R. Cartwright, Aileen W. Li, Maxence O. Dellacherie +5 more

Inhibition of MICA and MICB Shedding Elicits NK-Cell–Mediated Immunity against Tumors Resistant to Cytotoxic T Cells

Cancer Immunology Research(2020)10.1158/2326-6066.cir-19-0483

N/A

0DataRank · unranked

120 citations

Sushil Kumar, Adrienne Luoma, Yoshinaga Ito, Pedro Henrique Alves da Silva, Deng Pan +4 more

Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells

The Journal of Experimental Medicine(2020)10.1084/jem.20191453

N/A

0DataRank · unranked

69 citations

Olamide Olawoyin, Paloma Cejas, Yingtian Xie, Clifford A. Meyer, Yoshinaga Ito +7 more

Inhibition of MAN2A1 Enhances the Immune Response to Anti–PD-L1 in Human Tumors

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-20-0778

N/A

0DataRank · unranked

56 citations

Shengqing Gu, Tong Han, Wubing Zhang, Lei Huang, Ziyi Li +9 more

Understanding and treating the inflammatory adverse events of cancer immunotherapy

Cell(2021)10.1016/j.cell.2021.02.011

N/A

0DataRank · unranked

304 citations

Adrienne Luoma, Stephanie K. Dougan, Kai W. Wucherpfennig, Michael Dougan

Systematic investigation of cytokine signaling activity at the tissue and single-cell levels

Nature Methods(2021)10.1038/s41592-021-01274-5

N/A

0DataRank · unranked

261 citations

Yu Zhang, Beibei Ru, Yu-an Yang, Trang Vu, Rohit Paul +7 more

Inhibition of CDK4/6 Promotes CD8 T-cell Memory Formation

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1540

N/A

0DataRank · unranked

125 citations

Lestat R. Ali, Eleanor Clancy-Thompson, Li Qiang, Katherine S. Ventre, Patrick Lenehan +19 more

CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1144

N/A

0DataRank · unranked

98 citations

Zexian Zeng, Archis Bagati, Rong En Tay, Lionel A. Sanz, Stella R. Hartono +17 more

Designing Cancer Immunotherapies That Engage T Cells and NK Cells

Annual Review of Immunology(2022)10.1146/annurev-immunol-101921-044122

N/A

0DataRank · unranked

207 citations

Kai W. Wucherpfennig, Oleksandr Kyrysyuk

MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets

Nature Communications(2022)10.1038/s41467-022-30257-z

N/A

0DataRank · unranked

160 citations

Nadia Boufaied, Tarek Hallal, Avery Feit, Anna de Polo, Adrienne Luoma +30 more