Lorena Saelices

ORCID: 0000-0002-1904-2150

Also affiliated with The University of Texas Southwestern Medical Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 22 papers. Top paper: “Detection of ATTR aggregates in the plasma of polyneuropathic patients with ATTR-V30M amyloidosis”.

Detection of ATTR aggregates in the plasma of polyneuropathic patients with ATTR-V30M amyloidosis

Amyloid(2024)10.1080/13506129.2024.2404073

N/A

0.269DataRank · unranked

5 citations

Lanie Wang, Justin L. Grodin, Ahmad Masri, Jeffery W. Kelly, Lorena Saelices +1 more

Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.08.582936

N/A

0.269DataRank · unranked

5 citations

Virender Singh, Shumaila Afrin, Preeti Singh, Maja Pękała, Yasmin Ahmed +8 more

Structural and molecular homogeneity of ATTRv-T60A amyloid fibrils across patients and organs

Structure(2025)10.1016/j.str.2025.09.008

N/A

0.165DataRank · unranked

2 citations

Binh A. Nguyen, Shumaila Afrin, Virender Singh, Bret M. Evers, John M. Shelton +15 more

Disease-associated patterns of acetylation stabilize tau fibril formation

Structure(2023)10.1016/j.str.2023.05.020

N/A

0DataRank · unranked

24 citations

Binh A. Nguyen, Vishruth Mullapudi, Yang Li, Lorena Saelices, Łukasz A. Joachimiak +1 more

Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils

Nature Communications(2023)10.1038/s41467-023-37865-3

N/A

0DataRank · unranked

27 citations

Jeannette T. Bowler, Christen E. Tai, M.R. Sawaya, Yi Xiao Jiang, Gustavo Garcia +23 more

Conformational inhibitors of protein aggregation

Current Opinion in Structural Biology(2023)10.1016/j.sbi.2023.102700

N/A

0DataRank · unranked

4 citations

Shumaila Afrin, Lorena Saelices, María del Carmen Fernández‐Ramírez

O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.07.531573

N/A

0DataRank · unranked

9 citations

Anne‐Laure Mahul‐Mellier, Binh A. Nguyen, Mian Horvath, Afraah Javed, Eldon R. Hard +11 more

Disease-associated patterns of acetylation stabilize tau fibril formation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.10.523459

N/A

0DataRank · unranked

3 citations

Binh A. Nguyen, Vishruth Mullapudi, Lorena Saelices, Łukasz A. Joachimiak, Li Li

O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology

Nature Chemical Biology(2024)10.1038/s41589-024-01551-2

N/A

0DataRank · unranked

83 citations

Anne‐Laure Mahul‐Mellier, Binh A. Nguyen, Mian Horvath, Afraah Javed, Eldon R. Hard +11 more

Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy

Nature Communications(2024)10.1038/s41467-024-44820-3

N/A

0DataRank · unranked

62 citations

Virender Singh, Shumaila Afrin, Anna Yakubovska, Lanie Wang, Yasmin Ahmed +13 more

Detection of Circulating Transthyretin Amyloid Aggregates in Plasma: A Novel Biomarker for Transthyretin Amyloidosis

Circulation(2024)10.1161/circulationaha.123.067225

N/A

0DataRank · unranked

22 citations

Lanie Wang, Mazen Hanna, Merrill D. Benson, Justin L. Grodin, W. H. Wilson Tang +3 more

Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis

Communications Biology(2024)10.1038/s42003-024-06588-6

N/A

0DataRank · unranked

20 citations

Virender Singh, Shumaila Afrin, Preeti Singh, Maja Pękała, Yasmin Ahmed +8 more

ATTRv-V30M amyloid fibrils from heart and nerves exhibit structural homogeneity

Structure(2024)10.1016/j.str.2024.09.021

N/A

0DataRank · unranked

13 citations

Shumaila Afrin, Anna Yakubovska, Virender Singh, Rose Pedretti, Parker Bassett +8 more

Structure-Based Probe Reveals the Presence of Large Transthyretin Aggregates in Plasma of ATTR Amyloidosis Patients

JACC Basic to Translational Science(2024)10.1016/j.jacbts.2024.05.013

N/A

0DataRank · unranked

16 citations

Lanie Wang, Anna Yakubovska, Qiongfang S. Zhang, Binh A. Nguyen, Justin L. Grodin +3 more

Structure-based probe reveals the presence of large transthyretin aggregates in plasma of ATTR amyloidosis patients

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.09.584228

N/A

0DataRank · unranked

5 citations

Lanie Wang, Anna Yakubovska, Qiongfang S. Zhang, Binh A. Nguyen, Justin L. Grodin +3 more

ATTRv-V30M Type A amyloid fibrils from heart and nerves exhibit structural homogeneity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.14.594028

N/A

0DataRank · unranked

3 citations

Shumaila Afrin, Anna Yakubovska, Virender Singh, Jaime Vaquer Alicea, Peter Kunach +13 more

Mechanism of inhibition of acid-mediated transthyretin aggregation by designed peptides

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110594

N/A

0DataRank · unranked

1 citations

Rose Pedretti, H. Jane Dyson, Lorena Saelices, Peter E. Wright, Xun Sun

A Shared Amyloid Architecture in Cardiac Fibrils from Three Neuropathy-Associated ATTR Variants

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.05.667944

N/A

0DataRank · unranked

2 citations

Shumaila Afrin, Binh A. Nguyen, Virender Singh, Maja Pękała, Preeti Singh +8 more

Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores

Nature Structural & Molecular Biology(2021)10.1038/s41594-021-00646-x

N/A

0DataRank · unranked

90 citations

David R. Boyer, M.R. Sawaya, Romany Abskharon, Lorena Saelices, Binh A. Nguyen +5 more

Structural polymorphism of ex-vivo ALECT2 amyloid fibrils revealed by cryo-EM

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.15.664973

N/A

0DataRank · unranked

0 citations

Binh A. Nguyen, Virender Singh, Preeti Singh, Parker Bassett, Maja Pękała +10 more

Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.05.434000

N/A

0DataRank · unranked

24 citations

Xinyi Cheng, Christen E. Tai, Jeannette T. Bowler, Sarah L. Griner, M.R. Sawaya +19 more

Structural polymorphism of amyloid fibrils in cardiac transthyretin amyloidosis revealed by cryo-electron microscopy

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.21.496949

N/A

0DataRank · unranked

8 citations

Shumaila Afrin, Virender Singh, Yasmin Ahmed, Rose Pedretti, María del Carmen Fernández‐Ramírez +12 more