Robert Hromas

The University of Texas at San Antonio Health Science Center

ORCID: 0000-0002-1916-6276

Also affiliated with The University of Texas at San Antonio

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 44 papers. Top paper: “Drugging the Cancers Addicted to DNA Repair”.

Drugging the Cancers Addicted to DNA Repair

JNCI: Journal of the National Cancer Institute(2017)10.1093/jnci/djx059

N/A

5.4DataRank · unranked

164 citations

Dennie Jones, Suk-Hee Lee, Elizabeth A. Williamson, Robert Hromas, Jac A. Nickoloff

DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation

Nature Communications(2023)10.1038/s41467-023-36211-x

N/A

0.646DataRank · unranked

73 citations

Heike I. Rösner, Weixing Zhao, Platon Selemenakis, Zhuoling He, Ajinkya S. Kawale +17 more

Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair

Molecular Cell(2023)10.1016/j.molcel.2023.09.015

N/A

0.578DataRank · unranked

46 citations

Wenjing Li, Nozomi Tomimatsu, Corey H. Yu, Jae‐Hoon Ji, Salvador Alejo +21 more

Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions

Nature Communications(2020)10.1038/s41467-020-16903-4

N/A

0.553DataRank · unranked

39 citations

Nozomi Tomimatsu, Grace M. Hooks, Weibin Wang, Adam S. Miller, Xiaoyu Xue +8 more

Targeting pheochromocytoma/paraganglioma with polyamine inhibitors

Metabolism(2020)10.1016/j.metabol.2020.154297

N/A

0.470DataRank · unranked

22 citations

Fernando Bril, Heather Hatch, Yiling Xu, Laura M. Shelton, Srilaxmi Kalavalapalli +34 more

First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies

Journal of Hematology & Oncology(2025)10.1186/s13045-025-01753-8

N/A

0.436DataRank · unranked

14 citations

Minal Barve, Devalingam Mahalingam, Jay Parekh, Michael R. Kurman, James Strauss +10 more

PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1

Cell stem cell(2025)10.1016/j.stem.2025.01.010

N/A

0.396DataRank · unranked

13 citations

Pinpin Sui, Ying Li, Kaiyu Xu, Ji‐Hoon Lee, Juan Wang +20 more

Distinct roles of the two BRCA2 DNA-binding domains in DNA damage repair and replication fork preservation

Cell Reports(2025)10.1016/j.celrep.2025.115654

N/A

0.269DataRank · unranked

5 citations

Wenjing Li, Mollie E. Uhrig, Jeffrey N. Katz, Shahrez Syed, Neelam Sharma +14 more

Mechanism of SETX-BRCA1-BARD1 complex in resolution of R-loops and transcription-replication conflicts

Research Square(2024)10.21203/rs.3.rs-3833044/v1

N/A

0.269DataRank · unranked

5 citations

Arijit Dutta, Jae‐Hoon Ji, Qingming Fang, Shuo Zhou, Fengshan Liang +22 more

Trimming of damaged 3′ overhangs of DNA double-strand breaks by the Metnase and Artemis endonucleases

UNC Libraries(2021)10.17615/2qt6-th06

N/A

0DataRank · unranked

0 citations

Robert Hromas, Dale A. Ramsden, Steven M. Yannone, Susovan Mohapatra, Lawrence F. Povirk +3 more

M6A RNA Methylation Regulates Histone Ubiquitination to Support Cancer Growth and Progression

Cancer Research(2022)10.1158/0008-5472.can-21-2106

N/A

0DataRank · unranked

105 citations

Panneerdoss Subbarayalu, Daisy Medina, Saif Nirzhor, Santosh Timilsina, Subapriya Rajamanickam +12 more

Tumor Intrinsic PD-L1 Promotes DNA Repair in Distinct Cancers and Suppresses PARP Inhibitor–Induced Synthetic Lethality

Cancer Research(2022)10.1158/0008-5472.can-21-2076

N/A

0DataRank · unranked

70 citations

Jacob T. Boyd, Clare Murray, Julia Saifetiarova, Bárbara de la Peña Avalos, Cody M. Rogers +15 more

BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1

iScience(2022)10.1016/j.isci.2022.105626

N/A

0DataRank · unranked

18 citations

Gayathri Srinivasan, Ming Yang, Aruna S. Jaiswal, Taylor A. Totterdale, Linda G. Phillips +6 more

Resistance to the BCL-XL degrader DT2216 in T-cell acute lymphoblastic leukemia is rare and correlates with decreased BCL-XL proteolysis

Cancer Chemotherapy and Pharmacology(2022)10.1007/s00280-022-04490-8

N/A

0DataRank · unranked

19 citations

Aruna S. Jaiswal, Elizabeth A. Williamson, Jonathon Gelfond, Guangrong Zheng, Daohong Zhou +2 more

Metnase and EEPD1: DNA Repair Functions and Potential Targets in Cancer Therapy

Frontiers in Oncology(2022)10.3389/fonc.2022.808757

N/A

0DataRank · unranked

18 citations

Neelam Sharma, Lynn Taylor, Sage J. Allen, Suk‐Hee Lee, Robert Hromas +1 more

Targeting aberrant replication and DNA repair events for treating breast cancers

Communications Biology(2022)10.1038/s42003-022-03413-w

N/A

0DataRank · unranked

8 citations

Jun Hyoung Park, Panneerdoss Subbarayalu, Santosh Timilsina, Kaitlyn Bates, Pooja Yadav +20 more

Nucleases and Co-Factors in DNA Replication Stress Responses

DNA(2022)10.3390/dna2010006

N/A

0DataRank · unranked

10 citations

Neelam Sharma, Lynn Taylor, Sage J. Allen, Robert Hromas, Jac A. Nickoloff

Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102841

N/A

0DataRank · unranked

5 citations

Lijian Shao, Kimberly Richardson, Wen Ling, Aaron Warren, Kimberly J. Krager +6 more

RNA binding to human METTL3-METTL14 restricts N 6 -deoxyadenosine methylation of DNA in vitro

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.08.475504

N/A

0DataRank · unranked

0 citations

Javier Mota, Siu‐Hong Chan, Johanna Villarreal, Nan Dai, Shailee Arya +5 more

Co-targeting BCL-X L and MCL-1 with DT2216 and AZD8055 synergistically inhibits small-cell lung cancer growth without causing on-target toxicities in mice

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.12.507616

N/A

0DataRank · unranked

0 citations

Patrick Kellish, Nick Connis, Dinesh Thummuri, J Wiegand, Peiyi Zhang +14 more

Structural insights into BCDX2 complex function in homologous recombination

Nature(2023)10.1038/s41586-023-06219-w

N/A

0DataRank · unranked

52 citations

Lijia Jia, Aviv Meir, Shuo Zhou, Hardeep Kaur, Eliza A. Ruben +14 more

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

Cell Death Discovery(2023)10.1038/s41420-022-01296-8

N/A

0DataRank · unranked

43 citations

Patrick Kellish, Nick Connis, Dinesh Thummuri, J Wiegand, Peiyi Zhang +14 more

Cellular Responses to Widespread DNA Replication Stress

International Journal of Molecular Sciences(2023)10.3390/ijms242316903

N/A

0DataRank · unranked

31 citations

Aruna S. Jaiswal, Neelam Sharma, Elizabeth A. Williamson, Manh Tien Tran, Dominic Arris +3 more

Structural basis of RNA cap modification by SARS-CoV-2

Nature Communications(2020)10.1038/s41467-020-17496-8

N/A

0DataRank · unranked

246 citations

Shailee Arya, Siu‐Hong Chan, Shan Qi, Nan Dai, Anurag Misra +7 more

TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells

Nucleic Acids Research(2023)10.1093/nar/gkad952

N/A

0DataRank · unranked

15 citations

Arijit Dutta, Gayathri Srinivasan, Yaxia Yuan, Daohong Zhou, Montaser Shaheen +14 more

Data from Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence

(2023)10.1158/0008-5472.c.6513888.v1

N/A

0DataRank · unranked

0 citations

Suman Kanji, Nozomi Tomimatsu, Luis Fernando Macedo Di Cristofaro, Rahul K. Kollipara, Debabrata Saha +9 more

Data from M6A RNA Methylation Regulates Histone Ubiquitination to Support Cancer Growth and Progression

(2023)10.1158/0008-5472.c.6513931.v1

N/A

0DataRank · unranked

0 citations

Panneerdoss Subbarayalu, Daisy Medina, Saif Nirzhor, Santosh Timilsina, Subapriya Rajamanickam +12 more

MiR-223-3p promotes genomic stability of hematopoietic progenitors after radiation

Experimental Hematology(2023)10.1016/j.exphem.2023.10.002

N/A

0DataRank · unranked

0 citations

Gayathri Srinivasan, Aruna S. Jaiswal, Elizabeth A. Williamson, Lingxiao Li, Dominic Arris +4 more

Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL

Nature Communications(2024)10.1038/s41467-024-46922-4

N/A

0DataRank · unranked

49 citations

Dongwen Lv, Yaxia Yuan, Peiyi Zhang, Wanyi Hu, Anindita Nayak +8 more

Promotion of DNA end resection by BRCA1–BARD1 in homologous recombination

Nature(2024)10.1038/s41586-024-07910-2

N/A

0DataRank · unranked

35 citations

James M. Daley, Hardeep Kaur, Nozomi Tomimatsu, Chaoyou Xue, Vivek B. Raina +24 more

Colibactin Exerts Androgen-dependent and -independent Effects on Prostate Cancer

European Urology Oncology(2024)10.1016/j.euo.2024.10.015

N/A

0DataRank · unranked

3 citations

Sarah M. Al-Hiyari, Rupert Hugh-White, Robert Hromas, Yash Patel, Elizabeth A. Williamson +17 more

CD36-mediated endocytosis of proteolysis-targeting chimeras

Cell(2025)10.1016/j.cell.2025.03.036

N/A

0DataRank · unranked

50 citations

Bo‐Syong Pan, Rajesh Manne, Jungang Chen, Dongwen Lv, Minmin Wang +13 more

A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice

Nature Aging(2025)10.1038/s43587-025-00811-7

N/A

0DataRank · unranked

48 citations

Natacha Jn-Simon, Yonghan He, Chunbao Sun, Peiyi Zhang, Wanyi Hu +11 more

Epigenetic silencing of DNA sensing pathway by FOXM1 blocks stress ligand-dependent antitumor immunity and immune memory

Nature Communications(2025)10.1038/s41467-025-59186-3

N/A

0DataRank · unranked

9 citations

Jian Yu Huang, Nourhan Abdelfattah, Daisy Medina, Deepika Singh, Shahad Abdulsahib +17 more

The DNA Repair Component EEPD1 Regulates Actin Polymerization

Biology of the Cell(2025)10.1111/boc.70022

N/A

0DataRank · unranked

2 citations

Austin Kirby, Andrew Carrillo, Aruna Jasiwal, Kimi Kong, Manh Tien Tran +3 more

EEPD1 promotes repair of oxidatively-stressed replication forks

NAR Cancer(2023)10.1093/narcan/zcac044

N/A

0DataRank · unranked

17 citations

Hyun-Suk Kim, Orlando D. Schärer, Neelam Sharma, Elizabeth A. Williamson, Gayathri Srinivasan +13 more

Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies

Journal of Hematology & Oncology(2020)10.1186/s13045-020-00924-z

N/A

0DataRank · unranked

123 citations

Sajid Khan, Zhiguang Huo, Dongwen Lv, Xuan Zhang, Xingui Liu +6 more

Distinct roles of structure-specific endonucleases EEPD1 and Metnase in replication stress responses

NAR Cancer(2020)10.1093/narcan/zcaa008

N/A

0DataRank · unranked

14 citations

Michael Clayton Speed, Chris Allen, David G. Maranon, Elizabeth A. Williamson, Sudha Singh +3 more

Structural Basis of RNA Cap Modification by SARS-CoV-2 Coronavirus

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.26.061705

N/A

0DataRank · unranked

19 citations

Shailee Arya, Siu‐Hong Chan, Shan Qi, Nan Dai, Robert Hromas +5 more

Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence

Cancer Research(2021)10.1158/0008-5472.can-21-0752

N/A

0DataRank · unranked

201 citations

Suman Kanji, Nozomi Tomimatsu, Luis Fernando Macedo Di Cristofaro, Rahul K. Kollipara, Debabrata Saha +9 more

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity,

Nature Communications(2021)10.1038/s41467-021-27210-x

N/A

0DataRank · unranked

149 citations

Pratik Pal, Xingui Liu, Yannan Jia, Dinesh Thummuri, Peiyi Zhang +19 more

Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL–Specific Degrader DT2216

Molecular Cancer Therapeutics(2021)10.1158/1535-7163.mct-21-0474

N/A

0DataRank · unranked

74 citations

Sajid Khan, Patrick W. Underwood, Peiyi Zhang, J Wiegand, Xuan Zhang +13 more

The Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination

Frontiers in Genetics(2021)10.3389/fgene.2021.748033

N/A

0DataRank · unranked

29 citations

Neelam Sharma, Lynn Taylor, Sage J. Allen, Robert Hromas, Jac A. Nickoloff

Hem1 promotes osteoclast fusion and bone resorption in mice

Research Square(2021)10.21203/rs.3.rs-763477/v1

N/A

0DataRank · unranked

0 citations

Lijian Shao, Aaron Warren, Kimberly J. Krager, Nükhet Aykin‐Burns, Robert Hromas +4 more