De‐Chen Lin

ORCID: 0000-0002-1951-367X

Also affiliated with University of Dayton, USC Norris Comprehensive Cancer Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 25 papers. Top paper: “TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines”.

TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines

Gastroenterology(2020)10.1053/j.gastro.2020.06.050

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0DataRank · unranked

188 citations

Yuan Jiang, Chunquan Li, Ying Zhang, Pushkar Dakle, Harvinder Kaur +21 more

Lineage-Specific Epigenomic and Genomic Activation of Oncogene HNF4A Promotes Gastrointestinal Adenocarcinomas

Cancer Research(2020)10.1158/0008-5472.can-20-0390

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0DataRank · unranked

65 citations

Tiago C. Silva, Nicole Gull, Qian Yang, Jasmine Plummer, Stephanie Chen +15 more

EWS-FLI1 regulates and cooperates with core regulatory circuitry in Ewing sarcoma

Nucleic Acids Research(2020)10.1093/nar/gkaa901

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0DataRank · unranked

49 citations

Yueyuan Zheng, Liling Jiang, Bo Zhou, Wei Yang, Liyan Li +6 more

EWS-FLI1 regulates and cooperates with core regulatory circuitry in Ewing sarcoma

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.15.908475

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2 citations

Yueyuan Zheng, Liling Jiang, Bo Zhou, Wei Yang, Liyan Li +6 more

A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb targets

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.04.134858

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0DataRank · unranked

0 citations

Guowei Huang, Tiago C. Silva, Qian Yang, H. Phillip Koeffler, Benjamin P. Berman +2 more

Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment

Nature Communications(2021)10.1038/s41467-021-27599-5

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0DataRank · unranked

215 citations

Feng Pan, Geng Wang, Qingfeng Huang, Claire Olingy, Zhi‐Yong Wu +16 more

Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer

Nature Communications(2021)10.1038/s41467-021-24656-x

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0DataRank · unranked

132 citations

Qian Yang, Yan-Yi Jiang, Wei Yang, Yuan Jiang, Xiang Li +18 more

A Transcriptional Regulatory Loop of Master Regulator Transcription Factors, PPARG, and Fatty Acid Synthesis Promotes Esophageal Adenocarcinoma

Cancer Research(2021)10.1158/0008-5472.can-20-0652

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0DataRank · unranked

87 citations

Bo Zhou, Qian Yang, Yunzhi Pan, Wei Yang, Stephen J. Freedland +8 more

A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes

Nature Communications(2021)10.1038/s41467-021-22720-0

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0DataRank · unranked

54 citations

Guowei Huang, Tiago C. Silva, Qian Yang, Yan‐Yi Jiang, H. Phillip Koeffler +3 more

Generation and multiomic profiling of aTP53/CDKN2Adouble-knockout gastroesophageal junction organoid model

Science Translational Medicine(2022)10.1126/scitranslmed.abq6146

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0DataRank · unranked

49 citations

Yulan Cheng, Andrew Kalra, Ke Ma, Yueyuan Zheng, Benjamin Ziman +14 more

Genomic and Epigenomic Characterization of Tumor Organoid Models

Cancers(2022)10.3390/cancers14174090

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23 citations

Benjamin Ziman, Megha Sheth, Hua Zhao, De‐Chen Lin, Chehyun Nam

Investigation of early neoplastic transformation and premalignant biology using genetically engineered organoid models

Computational and Structural Biotechnology Journal(2022)10.1016/j.csbj.2022.09.026

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10 citations

Casey Collet, Dongzi Peng, Uttam K. Sinha, De‐Chen Lin, Hua Zhao

Single-cell genomics identifies immune response to neoadjuvant chemoradiotherapy

EBioMedicine(2022)10.1016/j.ebiom.2022.104389

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1 citations

W. Martin Kast, De‐Chen Lin, Uttam K. Sinha

Novel tumorigenic FOXM1-PTAFR-PTAF axis revealed by multi-omic profiling in TP53/CDKN2A- double knockout human gastroesophageal junction organoid model

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.10.491356

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0DataRank · unranked

2 citations

Yulan Cheng, Andrew Kalra, Ke Ma, Yueyuan Zheng, Benjamin Ziman +14 more

Comprehensive analyses of partially methylated domains and differentially methylated regions in esophageal cancer reveal both cell-type- and cancer-specific epigenetic regulation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.18.504390

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0DataRank · unranked

2 citations

Benjamin Ziman, Allen S. Ho, Uttam K. Sinha, Li-Yan Xu, En‐Min Li +4 more

Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics

Nature Communications(2023)10.1038/s41467-023-42960-6

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12 citations

De‐Chen Lin, Young Min Park

Treatment for ovarian clear cell carcinoma with combined inhibition of WEE1 and ATR

Journal of Ovarian Research(2023)10.1186/s13048-023-01160-y

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8 citations

Jeffrey Tyner, Sigal Gery, Yueyuan Zheng, Liyan Li, Mohan Shankar Gopinatha Pillai +5 more

Large-scale genomic analyses reveal alterations and mechanisms underlying clonal evolution and immune evasion in esophageal cancer

Nature Communications(2023)10.1038/s41467-023-36557-2

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5 citations

De‐Chen Lin

A novel role of master regulator transcription factor in anti-tumor immunity and cancer immunotherapy

Theranostics(2023)10.7150/thno.83486

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4 citations

De‐Chen Lin, Uttam K. Sinha

Epigenomic Analyses Identify FOXM1 As a Key Regulator of Anti-Tumor Immune Response in Esophageal Adenocarcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.28.551066

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0DataRank · unranked

1 citations

Qian Yang, Yueyuan Zheng, Megha Sheth, Chehyun Nam, Hua Zhao +3 more

Epigenomic analyses identify FOXM1 as a key regulator of anti-tumor immune response in esophageal adenocarcinoma

Cell Death and Disease(2024)10.1038/s41419-024-06488-x

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0DataRank · unranked

14 citations

Qian Yang, Yueyuan Zheng, Megha Sheth, Chehyun Nam, Hua Zhao +6 more

Patient-derived tumor organoids to model drug response in gastric cancer

Cell Reports Medicine(2024)10.1016/j.xcrm.2024.101650

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9 citations

Hua Zhao, Parish P. Sedghizadeh, De‐Chen Lin, Anette Vistoso Monreal

The MLL3/GRHL2 complex regulates malignant transformation and anti-tumor immunity in squamous cancer

The Journal of Experimental Medicine(2025)10.1084/jem.20240758

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4 citations

Guowei Huang, Yueyuan Zheng, Hua Zhao, Yuhao Pan, Boyan Hu +11 more

Genetically Defined Organoid Models Reveal Mechanisms Driving Squamous Cell Neoplastic Evolution and Identify Potential Therapeutic Vulnerabilities

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.18.631624

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2 citations

Young Min Park, Yueyuan Zheng, Qiong Mao, Casey Collet, Boyan Hu +10 more

ETS1 Orchestrates a Hybrid EMT Program Driving in vivo Metastasis and Immune Evasion

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.17.665404

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0DataRank · unranked

0 citations

Talia A. Wenger, Chehyun Nam, Qian Yang, D Arnaudov, Megha Sheth +8 more