🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Jon C. Aster

Brigham and Women's Hospital

ORCID: 0000-0002-1957-9070

Also affiliated with Harvard University

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile
5.6Author DataRank

Indexed papers

1in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

Cell(2020)10.1016/j.cell.2020.03.053
Top 4%
5.6DataRank
Top 4%609 citations

Aviv Regev, Philipp Oberdoerffer, Tal Nawy, Anna Hupalowska, Jennifer E. Rood +92 more

Papers

Driven by 28 papers — median percentile 96. Top paper: “Notch signalling in T‐cell lymphoblastic leukaemia/lymphoma and other haematological malignancies”.

Notch signalling in T‐cell lymphoblastic leukaemia/lymphoma and other haematological malignancies

The Journal of Pathology(2010)10.1002/path.2789
N/A
8.7DataRank · unranked
161 citations

Stephen C. Blacklow, Warren S. Pear, Jon C. Aster

Recruited macrophages elicit atrial fibrillation

Science(2023)10.1126/science.abq3061
N/A
5.9DataRank · unranked
216 citations

Maximilian J. Schloss, I‐Hsiu Lee, Aneesh Bapat, Yoshiko Iwamoto, Claudio Vinegoni +33 more

The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

Cell(2020)10.1016/j.cell.2020.03.053
Top 4%
5.6DataRank
Top 4%609 citations

Aviv Regev, Philipp Oberdoerffer, Tal Nawy, Anna Hupalowska, Jennifer E. Rood +92 more

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

Proceedings of the National Academy of Sciences(2011)10.1073/pnas.1114669108
N/A
0.923DataRank · unranked
468 citations

Zachary Sanborn, Kelly L. Arnett, Laura J. Bayston, Wilson Liao, Charlotte M. Proby +33 more

IER5, a DNA damage response gene, is required for Notch-mediated induction of squamous cell differentiation

eLife(2020)10.7554/elife.58081
N/A
0.793DataRank · unranked
22 citations

Madeleine E. Lemieux, Tom Thomas, Julia M. Rogers, Colin H. Lipper, Winston Lee +8 more

Shortwave-infrared meso-patterned imaging enables label-free mapping of tissue water and lipid content

Nature Communications(2020)10.1038/s41467-020-19128-7
N/A
0.666DataRank · unranked
84 citations

Anahita Pilvar, Anup Tank, Hannah Peterson, John Jiang, Jon C. Aster +4 more

Loss of glucocorticoid receptor expression mediates in vivo dexamethasone resistance in T-cell acute lymphoblastic leukemia

Leukemia(2020)10.1038/s41375-020-0748-6
N/A
0.557DataRank · unranked
40 citations

Benjamin J. Huang, Jeffrey W. Craig, Kathryn Hayes, Hannah H. Yan, Lauren K. Meyer +18 more

A multi-adjuvant personal neoantigen vaccine generates potent immunity in melanoma

Cell(2025)10.1016/j.cell.2025.06.019
N/A
0.520DataRank · unranked
31 citations

Derin B. Keskin, Chloe Ran Tu, Cleo Forman, Allison P. Vanasse, Haley E. Sax +39 more

Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma

Cell Reports(2022)10.1016/j.celrep.2022.111743
N/A
0.489DataRank · unranked
25 citations

Avishai Wizel, Daniel Davis, Armida Lefranc-Torres, Alejandro I. Rodarte-Rascon, Lauren E. Miller +10 more

A spatiotemporal Notch interaction map from plasma membrane to nucleus

Science Signaling(2023)10.1126/scisignal.adg6474
N/A
0.470DataRank · unranked
22 citations

Gary A. Bradshaw, Robyn J. Eisert, Emily D. Egan, Lena Tveriakhina, Julia M. Rogers +7 more

Molecular Mechanism of PP2A/B55α Phosphatase Inhibition by IER5

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.29.555174
N/A
0.208DataRank · unranked
3 citations

Daniel T.D. Jones, Pan Li, Annie Yang, Shumei Wang, Sathish K.R. Padi +4 more

Temporal Dynamics and Stoichiometry in Notch Signaling - from Notch Synaptic Complex Formation to NICD Nuclear Entry

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.27.559780
N/A
0DataRank · unranked
0 citations

Gustavo Scanavachi, Emily D. Egan, Ricardo Bango Da Cunha Correia, Alexandre Martin, Julia M. Rogers +5 more

Temporal dynamics and stoichiometry in human Notch signaling from Notch synaptic complex formation to nuclear entry of the Notch intracellular domain

Developmental Cell(2024)10.1016/j.devcel.2024.03.021
N/A
0DataRank · unranked
13 citations

Gustavo Scanavachi, Emily D. Egan, Ricardo Bango Da Cunha Correia, Alexandre Martin, Julia M. Rogers +5 more

Structural requirements for activity of Mind bomb1 in Notch signaling

Structure(2024)10.1016/j.str.2024.07.011
N/A
0DataRank · unranked
9 citations

Oren Gozlan, Alina Airich, Lena Tveriakhina, Haixia Zhou, Hanjie Jiang +6 more

Notch induces transcription by stimulating release of paused RNA polymerase II

Genes & Development(2024)10.1101/gad.352108.124
N/A
0DataRank · unranked
10 citations

Claudia A. Mimoso, Benjamín Martín, Alexandre Martin, Jon C. Aster, Karen Adelman +2 more

Notch induces transcription by stimulating release of paused RNA Pol II without increasing chromatin accessibility

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.13.598853
N/A
0DataRank · unranked
0 citations

Claudia A. Mimoso, Benjamín Martín, Alexandre Martin, Jon C. Aster, Karen Adelman +2 more

Molecular mechanism of PP2A/B55α phosphatase inhibition by IER5

Cell chemical biology(2025)10.1016/j.chembiol.2025.03.004
N/A
0DataRank · unranked
4 citations

Daniel T.D. Jones, Pan Li, Annie Yang, Shumei Wang, Sathish K.R. Padi +4 more

Single-cell and clonal analysis of AL amyloidosis plasma cells and their bone marrow microenvironment

Blood(2025)10.1182/blood.2024024719
N/A
0DataRank · unranked
2 citations

Maria Moscvin, Matteo Da Vià, Francesca Lazzaroni, Alice Nevone, Sam Sadigh +20 more

MAML1-Dependent Notch-Responsive Genes Exhibit Differing Cofactor Requirements for Transcriptional Activation

Molecular and Cellular Biology(2020)10.1128/mcb.00014-20
N/A
0DataRank · unranked
19 citations

Bingqian Guo, Emily D. Egan, Jon C. Aster, Karen Adelman, Stephen C. Blacklow +1 more

Contribution of clonal hematopoiesis to adult-onset hemophagocytic lymphohistiocytosis

Blood(2020)10.1182/blood.2020008206
N/A
0DataRank · unranked
33 citations

Adam S. Sperling, Christopher J. Gibson, Kaushik Viswanathan, Cecilia A. Castellano, Marie McConkey +16 more

Varying co-factor requirements for MAML1-dependent transcription at different Notch-responsive target genes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.13.905612
N/A
0DataRank · unranked
0 citations

Bingqian Guo, Emily D. Egan, Jon C. Aster, Karen Adelman, Stephen C. Blacklow +1 more

IER5 , a DNA-damage response gene, is required for Notch-mediated induction of squamous cell differentiation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.21.051730
N/A
0DataRank · unranked
0 citations

Madeleine E. Lemieux, Tom Thomas, Julia M. Rogers, Winston Lee, C. Anderson Johnson +7 more

FcγR engagement reprograms neutrophils into antigen cross-presenting cells that elicit acquired anti-tumor immunity

Nature Communications(2021)10.1038/s41467-021-24591-x
N/A
0DataRank · unranked
127 citations

Xavier Culleré, Joseph Mears, Florencia Rosetti, Koshu Okubo, Pei Xiong Liew +10 more

Primary cytotoxic T-cell lymphomas harbor recurrent targetable alterations in the JAK-STAT pathway

Blood(2021)10.1182/blood.2021012536
N/A
0DataRank · unranked
30 citations

Mark G. Evans, Lei Yang, Spencer Ng, Caroline Snowden, Michael S. Khodadoust +18 more

AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling

Cell Death and Disease(2022)10.1038/s41419-022-05133-9
N/A
0DataRank · unranked
39 citations

Vasudha Mishra, Elad Herz, Adar Yaacov, Oz Solomon, Rami Rauch +15 more

A Spatiotemporal Notch Interaction Map from Membrane to Nucleus

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.21.521435
N/A
0DataRank · unranked
0 citations

Gary A. Bradshaw, Robyn J. Eisert, Emily D. Egan, Lena Tveriakhina, Julia M. Rogers +7 more

A novel cryopreservation and biobanking strategy to study lymphoid tissue stromal cells in human disease

European Journal of Immunology(2023)10.1002/eji.202250362
N/A
0DataRank · unranked
6 citations

Angelina De Martin, Mechthild Lütge, Antonio Ferreira, Brian T. Gaudette, Yves Stanossek +13 more

A novel cryopreservation and biobanking strategy to study lymphoid tissue stromal cells in human disease

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.06.525604
N/A
0DataRank · unranked
0 citations

Angelina De Martin, Mechthild Lütge, Antonio Ferreira, Brian T. Gaudette, Yves Stanossek +12 more