Bruce J. Melancon

ORCID: 0000-0002-1958-0071

Also affiliated with Center for Discovery

NeuroscienceEngineeringMaterials ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 5 papers. Top paper: “Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials”.

Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.4c00769

N/A

0.457DataRank · unranked

11 citations

Michael R. Wood, Changho Han, Shaun R. Stauffer, Joseph D. Panarese, Bruce J. Melancon +21 more

Structural basis of allosteric modulation of metabotropic glutamate receptor activation and desensitization

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.13.552748

N/A

0DataRank · unranked

3 citations

Alberto J. Gonzalez-Hernandez, Joon Lee, Nohely Abreu, Purushotham Selvakumar, Leslie Salas-Estrada +8 more

Structural basis of positive allosteric modulation of metabotropic glutamate receptor activation and internalization

Nature Communications(2024)10.1038/s41467-024-50548-x

N/A

0DataRank · unranked

17 citations

Alberto J. Gonzalez-Hernandez, Joon Lee, Nohely Abreu, Purushotham Selvakumar, Leslie Salas-Estrada +10 more

Discovery of VU6024578/BI02982816: An mGlu1 Positive Allosteric Modulator with Efficacy in Preclinical Antipsychotic and Cognition Models

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c02554

N/A

0DataRank · unranked

3 citations

Jacob F. Kalbfleisch, Jeremy A. Turkett, Trevor A. Trombley, Anthony F. Nastase, Paul K. Spearing +17 more

Further Optimization of the mGlu1 PAM VU6024578/BI02982816: Discovery and Characterization of VU6033685

ACS Chemical Neuroscience(2025)10.1021/acschemneuro.5c00014

N/A

0DataRank · unranked

0 citations

Jacob F. Kalbfleisch, Jeremy A. Turkett, Trevor A. Trombley, Paul K. Spearing, Daniel H. Haymer +16 more