Umesh R. Desai

ORCID: 0000-0002-1976-6597

Biochemistry, Genetics and Molecular BiologyMedicineChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 22 papers. Top paper: “Discovering small-molecule therapeutics against SARS-CoV-2”.

Discovering small-molecule therapeutics against SARS-CoV-2

Drug Discovery Today(2020)10.1016/j.drudis.2020.06.017

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104 citations

Jacob C. Beer, Nehru Viji Sankaranarayanan, Michelle Swanson‐Mungerson, Umesh R. Desai, Vaibhav Tiwari

Inhibition of Human Cytomegalovirus Entry into Host Cells through A Pleiotropic Small Molecule

International Journal of Molecular Sciences(2020)10.3390/ijms21051676

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11 citations

Dominik D. Kaltenbach, Vraj R. Patel, Max T. Nguyen, Harsh Sharthiya, Ritesh Tandon +6 more

Combinatorial virtual library screening analysis of antithrombin binding oligosaccharide motif generation by heparan sulfate 3- O -Sulfotransferase 1

Computational and Structural Biotechnology Journal(2020)10.1016/j.csbj.2020.03.008

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15 citations

Yiling Bi, Balagurunathan Kuberan, Umesh R. Desai, Nehru Viji Sankaranarayanan

Discovery of Sulfated Small Molecule Inhibitors of Matrix Metalloproteinase-8

Biomolecules(2020)10.3390/biom10081166

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8 citations

Umesh R. Desai, Shravan Morla

Structural Insights Into How Proteoglycans Determine Chemokine-CXCR1/CXCR2 Interactions: Progress and Challenges

Frontiers in Immunology(2020)10.3389/fimmu.2020.00660

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40 citations

Umesh R. Desai, Krishna Rajarathnam

Enzyme immobilization offers a robust tool to scale up the production of longer, diverse, natural glycosaminoglycan oligosaccharides

Glycobiology(2020)10.1093/glycob/cwaa027

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3 citations

Umesh R. Desai, Alhumaidi B. Alabbas

Preferential recognition and antagonism of SARS-CoV-2 spike glycoprotein binding to 3- O -sulfated heparan sulfate

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.08.331751

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22 citations

Ritesh Tandon, Nehru Viji Sankaranarayanan, Jacob C. Beer, Ellen K. Kohlmeir, Michelle Swanson‐Mungerson +2 more

Combinatorial Virtual Library Screening Study of Transforming Growth Factor-β2–Chondroitin Sulfate System

International Journal of Molecular Sciences(2021)10.3390/ijms22147542

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10 citations

Balaji Nagarajan, Umesh R. Desai, Nehru Viji Sankaranarayanan

Heparan Sulfate Microarray Lends Insight into Selective Binding of SARS‐CoV‐2 Spike Glycoprotein

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.01674

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0 citations

Nehru Viji Sankaranarayanan, Connor P. O’Hara, Umesh R. Desai, John E. Chittum

In-Depth Molecular Dynamics Study of All Possible Chondroitin Sulfate Disaccharides Reveals Key Insight into Structural Heterogeneity and Dynamism

Biomolecules(2022)10.3390/biom12010077

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9 citations

Nehru Viji Sankaranarayanan, Umesh R. Desai, Balaji Nagarajan

3- O -Sulfation induces sequence-specific compact topologies in heparan sulfate that encode a dynamic sulfation code

Computational and Structural Biotechnology Journal(2022)10.1016/j.csbj.2022.07.013

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13 citations

Balaji Nagarajan, Umesh R. Desai, Samuel G. Holmes

The alphaherpesvirus conserved pUS10 is important for natural infection and its expression is regulated by the conserved Herpesviridae protein kinase (CHPK)

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.31.514468

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0 citations

Haji Akbar, Justine Arrington, Stephen J. Spatz, Balaji Nagarajan, Umesh R. Desai +2 more

Homogeneous, Synthetic, Non-Saccharide Glycosaminoglycan Mimetics as Potent Inhibitors of Human Cathepsin G

Biomolecules(2023)10.3390/biom13050760

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4 citations

Rawan Fayyad, Valerie R. Puliafico, Spencer Merrell, Eltice K. Langmia, Sophie R. Diagne +3 more

Designing Synthetic, Sulfated Glycosaminoglycan Mimetics That Are Orally Bioavailable and Exhibiting In Vivo Anticancer Activity

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c01511

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11 citations

Ongolu Ravikumar, Connor O’Hara, Rio S. Boothello, Alberto Vera, Elsamani I. Abdelfadiel +8 more

The alphaherpesvirus conserved pUS10 is important for natural infection and its expression is regulated by the conserved Herpesviridae protein kinase (CHPK)

PLoS Pathogens(2023)10.1371/journal.ppat.1010959

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8 citations

Haji Akbar, Justine Arrington, Stephen J. Spatz, Balaji Nagarajan, Umesh R. Desai +2 more

Merging cultures and disciplines to create a drug discovery ecosystem at Virginia commonwealth university: Medicinal chemistry, structural biology, molecular and behavioral pharmacology and computational chemistry

SLAS DISCOVERY(2023)10.1016/j.slasd.2023.02.006

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4 citations

Yana Cen, Maƚgorzata Dukat, Keith C. Ellis, Youzhong Guo, Jiong Li +6 more

Assessing Genetic Algorithm-Based Docking Protocols for Prediction of Heparin Oligosaccharide Binding Geometries onto Proteins

Biomolecules(2023)10.3390/biom13111633

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3 citations

Umesh R. Desai, Samuel G. Holmes

Glycosaminoglycan microarrays for studying glycosaminoglycan–protein systems

Carbohydrate Polymers(2024)10.1016/j.carbpol.2024.122106

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12 citations

A.Ronald Thompson, Umesh R. Desai, John E. Chittum

Design and Synthesis of Small Molecule Probes of MDA-9/Syntenin

Biomolecules(2024)10.3390/biom14101287

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6 citations

Bharath Kumar Villuri, Balaji Nagarajan, Sarah A. Lewicki, Swadesh K. Das, Paul B. Fisher +2 more

Synthesis and Reactivity of Masked Organic Sulfates

Chemistry - A European Journal(2024)10.1002/chem.202402268

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4 citations

Umesh R. Desai, Bharath Kumar Villuri

Alteration of Neuropilin-1 and Heparan Sulfate Interaction Impairs Murine B16 Tumor Growth

ACS Chemical Biology(2024)10.1021/acschembio.4c00389

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2 citations

Nehru Viji Sankaranarayanan, B. Nagarajan, Thomas Mandel Clausen, Alan M.V. West, Nicollette J. Setiawan +14 more

A Robust Proteomics-Based Method for Identifying Preferred Protein Targets of Synthetic Glycosaminoglycan Mimetics

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.23.634492

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1 citations

Ongolu Ravikumar, Rawan Fayyad, Adam M. Hawkridge, Umesh R. Desai, Daniel K. Afosah