Joseph H. Lee

Columbia University Irving Medical Center

ORCID: 0000-0002-2000-4821

Also affiliated with Columbia University

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.1Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium–Down Syndrome (ABC–DS) study

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12039

Top 30%

0.674DataRank

Top 30%23 citations

Fan Zhang, Nicole Schupf, Sharon J. Krinsky‐McHale, James Hall, Mark Mapstone +18 more

Papers

Driven by 48 papers — median percentile 63. Top paper: “Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium–Down Syndrome (ABC–DS) study”.

Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium–Down Syndrome (ABC–DS) study

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12039

Top 30%

0.674DataRank

Top 30%23 citations

Fan Zhang, Nicole Schupf, Sharon J. Krinsky‐McHale, James Hall, Mark Mapstone +18 more

Individualized estimated years from onset of Alzheimer's disease– related decline for adults with Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2023)10.1002/dad2.12444

Top 44%

0.426DataRank

Top 44%8 citations

Sharon J. Krinsky‐McHale, Cynthia Kovacs, Joseph H. Lee, Tracy Listwan, Deborah Pang +3 more

Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer’s Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome

Journal of Alzheimer s Disease(2020)10.3233/jad-201167

N/A

0DataRank · unranked

53 citations

Michael S. Rafii, Fan Zhang, James Hall, David Julovich, Beau M. Ances +20 more

Proteomic profiles of prevalent mild cognitive impairment and Alzheimer's disease among adults with Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12023

N/A

0DataRank · unranked

16 citations

Fan Zhang, Sharon J. Krinsky‐McHale, Wayne Silverman, Joseph H. Lee, Deborah Pang +4 more

Proteomic profiles of incident mild cognitive impairment and Alzheimer's disease among adults with Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12033

N/A

0DataRank · unranked

11 citations

Fan Zhang, Wayne Silverman, Joseph H. Lee, Sharon J. Krinsky‐McHale, Deborah Pang +3 more

Nighttime Blood Pressure Interacts with APOE Genotype to Increase the Risk of Incident Dementia of the Alzheimer’s Type in Hispanics

Journal of Alzheimer s Disease(2020)10.3233/jad-200430

N/A

0DataRank · unranked

4 citations

Daniel Camilo Aguirre-Acevedo, Ciro Gaona, Carlos Chávez, Gustavo Calmón, Eglé R. Silva +9 more

Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2021)10.1016/s1474-4422(21)00139-3

N/A

0DataRank · unranked

71 citations

Rachel L. Henson, Yan Li, Anna H. Boerwinkle, Chengjie Xiong, Randall J. Bateman +29 more

The Association between Sex and Risk of Alzheimer’s Disease in Adults with Down Syndrome

Journal of Clinical Medicine(2021)10.3390/jcm10132966

N/A

0DataRank · unranked

17 citations

Joseph H. Lee, Deborah Pang, Warren B. Zigman, Benjamin Tycko, Sharon J. Krinsky‐McHale +4 more

Total Plasma Homocysteine and Depressive Symptoms in Older Hispanics

Journal of Alzheimer s Disease(2021)10.3233/jad-201062

N/A

0DataRank · unranked

11 citations

Jesús D. Melgarejo, Carlos Chávez, Gabriel A. de Erausquin, Joseph D. Terwilliger, Joseph H. Lee +2 more

Normal-tension glaucomatous optic neuropathy is related to blood pressure variability in the Maracaibo Aging Study

Hypertension Research(2021)10.1038/s41440-021-00687-1

N/A

0DataRank · unranked

11 citations

Gladys E. Maestre, Luis J. Mena, Joseph H. Lee, Michele Petitto, Carlos Chávez +12 more

Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus

Neurobiology of Aging(2021)10.1016/j.neurobiolaging.2021.02.019

N/A

0DataRank · unranked

7 citations

Briseida E. Feliciano‐Astacio, Holly N. Cukier, Liyong Wang, Anthony J. Griswold, Kara L. Hamilton‐Nelson +26 more

Research on aging during the Venezuelan humanitarian crisis: the experience of the Maracaibo aging study

BMC Public Health(2021)10.1186/s12889-021-10526-0

N/A

0DataRank · unranked

0 citations

Rosa V. Pirela, Carmen Laura Paz Reverol, Jesús D. Melgarejo, Luis J. Mena, Carlos Chávez +8 more

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2022)10.1016/s1474-4422(22)00408-2

N/A

0DataRank · unranked

56 citations

Brian A. Gordon, Julie K. Wisch, Shaney Flores, Rachel L. Henson, Omar H. Butt +95 more

Obstructive sleep apnea, cerebrovascular disease, and amyloid in older adults with Down syndrome across the Alzheimer’s continuum

SLEEP Advances(2022)10.1093/sleepadvances/zpac013

N/A

0DataRank · unranked

20 citations

Molly E. Zimmerman, Sigan L. Hartley, José Gutierrez, David B. Keator, Kay C. Igwe +16 more

Weight Loss and Alzheimer’s Disease in Down Syndrome

Journal of Alzheimer s Disease(2022)10.3233/jad-220865

N/A

0DataRank · unranked

12 citations

Brian C. Helsel, Lauren T. Ptomey, H. Diana Rosas, Benjamin L. Handen, Charles M. Laymon +10 more

Probing the proteome to explore potential correlates of increased Alzheimer's‐related cerebrovascular disease in adults with Down syndrome

Alzheimer s & Dementia(2022)10.1002/alz.12627

N/A

0DataRank · unranked

12 citations

Melissa Petersen, Fan Zhang, Patrick J. Lao, Molly E. Zimmerman, Yian Gu +19 more

Triplication of Synaptojanin 1 in Alzheimer’s Disease Pathology in DownSyndrome

Current Alzheimer Research(2022)10.2174/1567205020666221202102832

N/A

0DataRank · unranked

4 citations

Lam‐Ha T. Dang, Jacinda Chen, Joseph H. Lee, Catherine Marquer, Robert Hwang

Open-Angle Glaucomatous Optic Neuropathy Is Related to Dips Rather Than Increases in the Mean Arterial Pressure Over 24-H

American Journal of Hypertension(2022)10.1093/ajh/hpac028

N/A

0DataRank · unranked

5 citations

Jan Van Eijgen, Gladys E. Maestre, Lama A. Al‐Aswad, Lutgarde Thijs, Luis J. Mena +18 more

Substantial Fat Loss in Physique Competitors Is Characterized by Increased Levels of Bile Acids, Very-Long Chain Fatty Acids, and Oxylipins

Metabolites(2022)10.3390/metabo12100928

N/A

0DataRank · unranked

5 citations

Juha J. Hulmi, Youwen Qin, Michael Inouye, Scott C. Ritchie, Susan Cheng +15 more

Subclinical Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease in Relation to Office and Ambulatory Blood Pressure Measurements

Frontiers in Neurology(2022)10.3389/fneur.2022.908260

N/A

0DataRank · unranked

3 citations

Gladys E. Maestre, José Gutierrez, Lutgarde Thijs, Luis J. Mena, Ciro Gaona +13 more

Obesity, diabetes and their metabolic correlates in middle‐aged adults with Down syndrome

Journal of Intellectual Disability Research(2023)10.1111/jir.13103

N/A

0DataRank · unranked

14 citations

Deborah Pang, Sharon J. Krinsky‐McHale, Nicole Schupf, Joseph H. Lee, Wayne Silverman +2 more

Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome

Alzheimer s & Dementia(2023)10.1002/alz.13506

N/A

0DataRank · unranked

13 citations

Muhammad Aslam, Lam‐Ha T. Dang, Laura Xicota, María Victoria Fernández, Yun Ju Sung +16 more

Juvenile CLN3 disease is a lysosomal cholesterol storage disorder: similarities with Niemann-Pick type C disease

EBioMedicine(2023)10.1016/j.ebiom.2023.104628

N/A

0DataRank · unranked

12 citations

Rajesh K. Soni, Yimeng Xu, Sabrina Simoes, Feng-Xia Liang, Laura DeFreitas +8 more

Cerebrovascular disease drives Alzheimer plasma biomarker concentrations in adults with Down syndrome

medRxiv(2023)10.1101/2023.11.28.23298693

N/A

0DataRank · unranked

10 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +20 more

The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact

Alzheimer s & Dementia(2024)10.1002/alz.13836

N/A

0DataRank · unranked

87 citations

Gladys E. Maestre, Simin Mahinrad, Daisy M Acosta, Rufus Akinyemi, Suvarna Alladi +77 more

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2024)10.1016/s1474-4422(24)00084-x

N/A

0DataRank · unranked

36 citations

Nicole S. McKay, Anna H. Boerwinkle, James L. Kennedy, Shaney Flores, Benjamin L. Handen +86 more

Cerebrovascular disease is associated with Alzheimer’s plasma biomarker concentrations in adults with Down syndrome

Brain Communications(2024)10.1093/braincomms/fcae331

N/A

0DataRank · unranked

29 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +70 more

Whole genome‐wide sequence analysis of long‐lived families (Long‐Life Family Study) identifies MTUS2 gene associated with late‐onset Alzheimer's disease

Alzheimer s & Dementia(2024)10.1002/alz.13718

N/A

0DataRank · unranked

17 citations

Stephanie Cosentino, Badri N. Vardarajan, Richard Mayeux, Thomas T. Perls, Stacy L. Andersen +14 more

Cognitive and functional performance and plasma biomarkers of early Alzheimer's disease in Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2024)10.1002/dad2.12582

N/A

0DataRank · unranked

16 citations

Benjamin L. Handen, Melissa Petersen, Sid E. O’Bryant, Jamie C. Peven, Dana Tudorascu +17 more

Association of longitudinal changes in 24-h blood pressure level and variability with cognitive decline

Journal of Hypertension(2024)10.1097/hjh.0000000000003824

N/A

0DataRank · unranked

6 citations

Kristina Vatcheva, Silvia Mejía-Arango, Sokratis Charisis, Dhrumil Patil, Luis J. Mena +13 more

The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome

EBioMedicine(2024)10.1016/j.ebiom.2024.105433

N/A

0DataRank · unranked

6 citations

Lam‐Ha T. Dang, Alice Lee, Sharon J. Krinsky‐McHale, Deborah Pang, Lisa Melilli +72 more

Association of Variability and Hypertensive Loads in 24-h Blood Pressure With Mortality and Cardiovascular Risk

American Journal of Hypertension(2024)10.1093/ajh/hpae011

N/A

0DataRank · unranked

5 citations

Dhrumil Patil, Luis J. Mena, Kristina Vatcheva, José García, Claudia L. Satizábal +9 more

Prodromal Alzheimer's disease can affect activities of daily living for adults with Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2024)10.1002/dad2.12562

N/A

0DataRank · unranked

4 citations

Sharon J. Krinsky‐McHale, Cynthia Kovacs, Joseph H. Lee, Deborah Pang, Nicole Schupf +4 more

The Alzheimer's Biomarker Consortium–Down Syndrome (ABC‐DS): A 10‐year report

Alzheimer s & Dementia(2025)10.1002/alz.70294

N/A

0DataRank · unranked

21 citations

Mark Mapstone, Sigan L. Hartley, Howard Andrews, Brad T. Christian, Joseph H. Lee +20 more

Correlating hippocampal and amygdala volumes with neuropathological burden in Down syndrome and Alzheimer’s disease and related neurodegenerative pathologies using 7T postmortem MRI

Journal of Neuropathology & Experimental Neurology(2025)10.1093/jnen/nlaf010

N/A

0DataRank · unranked

6 citations

Jinghang Li, Jacob Berardinelli, Hecheng Jin, Tales Santini, Jaehoon Noh +69 more

Alzheimer's disease diagnostic progression is associated with cerebrovascular disease and neuroinflammation in adults with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70726

N/A

0DataRank · unranked

4 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +20 more

Examination of metabolic syndrome in Down syndrome and association with dementia

Alzheimer s & Dementia(2025)10.1002/alz.70799

N/A

0DataRank · unranked

3 citations

Lam‐Ha T. Dang, Laura Xicota, Sharon J. Krinsky‐McHale, Balaji Kannappan, Adam M. Brickman +8 more

A comparison of multiple amyloid PET radiotracers for Down syndrome clinical trials

Brain Communications(2025)10.1093/braincomms/fcaf406

N/A

0DataRank · unranked

2 citations

Julie C. Price, Bradley T. Christian, Michael S. Rafii, Beau M. Ances, Howard Andrews +51 more

Imaging and plasma biomarkers for pathological accumulation in Down syndrome

Brain(2025)10.1093/brain/awaf418

N/A

0DataRank · unranked

2 citations

Ziqiao Jiao, James T. Kennedy, Ann D. Cohen, Zinayida Schlachetzki, Melissa Petersen +21 more

The tau biomarker cascade is condensed in Down syndrome compared with sporadic Alzheimer’s disease

Brain(2025)10.1093/brain/awaf428

N/A

0DataRank · unranked

2 citations

Hailey Bruzzone, Karly Alex Cody, Jacob Morse, Rachael E. Wilson, Brecca Bettcher +65 more

Validity of one‐time assessments for identifying prodromal Alzheimer's disease in adults with Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2025)10.1002/dad2.70076

N/A

0DataRank · unranked

2 citations

Cynthia Kovacs, Joseph H. Lee, Tracy A. Listwan, Deborah Pang, Nicole Schupf +4 more

Perception of Quality of Life, Brain Regions, and Cognitive Performance in Hispanic Adults: A Canonical Correlation Approach

Clinical and Translational Neuroscience(2025)10.3390/ctn9030033

N/A

0DataRank · unranked

1 citations

Jesús D. Melgarejo, Jesús Rivera-Sánchez, Lorena Velázquez‐Álvarez, Isabel Omaña‐Guzmán, Carlos Curtis-Lopez +9 more

Baseline associations of office and ambulatory blood pressure monitoring with cognitive function and dementia prevalence

Journal of Alzheimer s Disease(2025)10.1177/13872877251322400

N/A

0DataRank · unranked

1 citations

D. A. Patil, Sokratis Charisis, Kristina Vatcheva, Silvia Mejía-Arango, Luis J. Mena +10 more

Utility of Polygenic Risk Scores in Families with Exceptional Longevity

medRxiv(2025)10.1101/2025.07.21.25331660

N/A

0DataRank · unranked

1 citations

Rong Cheng, Sandra Barral, Lawrence S. Honig, Nicole Schupf, Yian Gu +7 more

Genome‐wide association analyses identify candidate loci for amyloid imaging and plasma biomarkers in adults with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70358

N/A

0DataRank · unranked

0 citations

Lam‐Ha T. Dang, Ruyu Shi, Kang-Hsien Fan, Asma Naseer Cheema, Laura Xicota +16 more

The Alzheimer's Biomarker Consortium‐Down Syndrome: Rationale and methodology

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12065

N/A

0DataRank · unranked

122 citations

Ira T. Lott, Bradley T. Christian, Nicole Schupf, Sid E. O’Bryant, Mark Mapstone +17 more

Associations of Blood Pressure Level and Variability With Cortical Thickness: A Cross-Sectional Analysis From the Maracaibo Aging Study

American Journal of Hypertension(2025)10.1093/ajh/hpaf159

N/A

0DataRank · unranked

0 citations

Shana Garza, Silvia Mejía-Arango, Kristina Vatcheva, Sokratis Charisis, Claudia L. Satizábal +10 more

Promising outcome measures of early Alzheimer's dementia in adults with Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12044

N/A

0DataRank · unranked

59 citations

Warren B. Zigman, Joseph H. Lee, Nicole Schupf, Deborah Pang, Tracy Listwan +3 more

Joseph H. Lee

Indexed papers

Top data-sharing exemplar

Papers