Ronald C. Wek

ORCID: 0000-0002-2087-5504

Also affiliated with University of Indianapolis, Indiana Cancer Consortium, Indiana University School of Medicine, Indiana University – Purdue University Indianapolis, Indiana University

Biochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 31 papers. Top paper: “Multiple mechanisms activate GCN2 eIF2 kinase in response to diverse stress conditions”.

Multiple mechanisms activate GCN2 eIF2 kinase in response to diverse stress conditions

Nucleic Acids Research(2024)10.1093/nar/gkae006

N/A

1.1DataRank · unranked

57 citations

Kenneth R Carlson, Dan F. Spandau, Ronald C. Wek, Jagannath Misra

Toxoplasma gondii Co-opts the Unfolded Protein Response To Enhance Migration and Dissemination of Infected Host Cells

mBio(2020)10.1128/mbio.00915-20

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0DataRank · unranked

28 citations

Jennifer Martynowicz, Parth H. Amin, Nada S. Alakhras, Mark H. Kaplan, Ronald C. Wek +2 more

TgIF2K-B is an eIF2α kinase in Toxoplasma gondii that responds to oxidative stress and optimizes pathogenicity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.24.312744

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0DataRank · unranked

1 citations

Jennifer Martynowicz, Parth H. Amin, Kenneth R. Carlson, Ronald C. Wek, William J. Sullivan +1 more

Toxoplasma gondii co-opts the unfolded protein response to enhance migration and dissemination of infected host cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.14.042069

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0DataRank · unranked

0 citations

Jennifer Martynowicz, Parth H. Amin, Nada S. Alakhras, Mark H. Kaplan, Ronald C. Wek +2 more

Discordant regulation of eIF2 kinase GCN2 and mTORC1 during nutrient stress

Nucleic Acids Research(2021)10.1093/nar/gkab362

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0DataRank · unranked

46 citations

Michael J. Holmes, Emily T. Mirek, Michael J. Langevin, Hyeong-Geug Kim, Kenneth R Carlson +5 more

TgIF2K-B Is an eIF2α Kinase in Toxoplasma gondii That Responds to Oxidative Stress and Optimizes Pathogenicity

mBio(2021)10.1128/mbio.03160-20

N/A

0DataRank · unranked

38 citations

Jennifer Martynowicz, Parth H. Amin, Kenneth R. Carlson, Ronald C. Wek, William J. Sullivan +1 more

Disease-associated mutations in a bifunctional aminoacyl-tRNA synthetase gene elicit the integrated stress response

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101203

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0DataRank · unranked

26 citations

Sheree A. Wek, Nathan Kudlapur, William A. Cantara, Marina Bakhtina, Ronald C. Wek +2 more

The eIF2 kinase GCN2 directs keratinocyte collective cell migration during wound healing via coordination of reactive oxygen species and amino acids

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101257

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0DataRank · unranked

17 citations

Parth H. Amin, Miguel Barriera Diaz, Jagannath Misra, Erica Aukerman, Amitava Das +7 more

Nmp4, a Regulator of Induced Osteoanabolism, Also Influences Insulin Secretion and Sensitivity

Calcified Tissue International(2021)10.1007/s00223-021-00903-7

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0DataRank · unranked

5 citations

Sarah A. Tersey, Michele Adaway, Robert N. Bone, Amy Creecy, Angela J. Klunk +6 more

Inhibitor of Bruton's Tyrosine Kinase‐α (IBTKα) in the Unfolded Protein Response

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.05110

N/A

0DataRank · unranked

0 citations

Emily T. Mirek, Kirk A. Staschke, Tracy G. Anthony, Ronald C. Wek, Parth H. Amin

Asparagine bioavailability regulates the translation of MYC oncogene

Oncogene(2022)10.1038/s41388-022-02474-9

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0DataRank · unranked

18 citations

Jie Jiang, Jagannath Misra, Gretchen Seim, Kirk A. Staschke, Minghua Zhong +12 more

Activation and execution of the hepatic integrated stress response by dietary essential amino acid deprivation is amino acid specific

The FASEB Journal(2022)10.1096/fj.202200204rr

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0DataRank · unranked

17 citations

Emily T. Mirek, Ronald C. Wek, Tracy G. Anthony, William O. Jonsson

GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.17.496598

N/A

0DataRank · unranked

4 citations

Jagannath Misra, Parth H. Amin, Angela J. Klunk, Nur P. Damayanti, Kenneth R. Carlson +12 more

Targeting GCN2 Regulation of Amino Acid Homeostasis in Prostate Cancer

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.0r314

N/A

0DataRank · unranked

0 citations

Jagannath Misra, Parth H. Amin, Nur P. Damayanti, Kenneth R. Carlson, Angela J. Klunk +7 more

Surviving and Adapting to Stress: Translational Control and the Integrated Stress Response

Antioxidants and Redox Signaling(2023)10.1089/ars.2022.0123

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0DataRank · unranked

85 citations

Tracy G. Anthony, Kirk A. Staschke, Ronald C. Wek

Activation of Gcn2 by small molecules designed to be inhibitors

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104595

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0DataRank · unranked

66 citations

Millie M. Georgiadis, Feven Tameire, Kirk A. Staschke, Ronald C. Wek, Kenneth Carlson

NMP4, an Arbiter of Bone Cell Secretory Capacity and Regulator of Skeletal Response to PTH Therapy

Calcified Tissue International(2023)10.1007/s00223-023-01088-x

N/A

0DataRank · unranked

4 citations

Emily G. Atkinson, Michele Adaway, Angela J. Klunk, Ronald C. Wek, Deepak Vashishth +6 more

Insulin secretion deficits in a Prader-Willi syndrome β-cell model are associated with a concerted downregulation of multiple endoplasmic reticulum chaperones

PLoS Genetics(2023)10.1371/journal.pgen.1010710

N/A

0DataRank · unranked

3 citations

Marie A. Johnson, James J. Moresco, Patrizia Luppi, Dale W. Lewis, Donna B. Stolz +9 more

mRNA cap-binding protein eIF4E1 is a novel regulator of Toxoplasma gondii latency

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.09.561274

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0DataRank · unranked

14 citations

Matheus Silva e Bastos, Vishakha Dey, Vanessa Rossini Severo, Ronald C. Wek, William J. Sullivan +1 more

Phosphorylation of GCN2 by mTOR confers adaptation to conditions of hyper-mTOR activation under stress

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107575

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0DataRank · unranked

18 citations

Olaya Yassin, Miri Shmuel, Ronald C. Wek, Sayyed Jalil Mahdizadeh, Leif A. Eriksson +3 more

mRNA cap-binding protein eIF4E1 is a novel regulator of Toxoplasma gondii latency

mBio(2024)10.1128/mbio.02954-23

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0DataRank · unranked

19 citations

Matheus Silva e Bastos, Vishakha Dey, Vanessa Rossini Severo, Ronald C. Wek, William J. Sullivan +1 more

Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer

Science Signaling(2024)10.1126/scisignal.adp1375

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0DataRank · unranked

10 citations

Noah R. Sommers, Andrew Law, Angela J. Klunk, Kyla Brady, David W. Goodrich +6 more

Cap-independent translation directs stress-induced differentiation of the protozoan parasite Toxoplasma gondii

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107979

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0DataRank · unranked

4 citations

Michael J. Holmes, Matheus Silva e Bastos, Ronald C. Wek, William J. Sullivan, Vishakha Dey

Cap-independent translation directs stress-induced differentiation of the protozoan parasite Toxoplasma gondii

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.17.613578

N/A

0DataRank · unranked

0 citations

Michael J. Holmes, Matheus Silva e Bastos, Ronald C. Wek, William J. Sullivan, Vishakha Dey

Autophagy-related 7 (ATG7) regulates food intake and liver health during asparaginase exposure

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108171

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0DataRank · unranked

6 citations

Maria Ibrahim, Flavio C. Rodriguez-Polanco, Chintan T. Bhavsar, Esther Rodríguez, Eduardo Cararo Lopes +6 more

The oligosaccharyltransferase complex is an essential component of multiple myeloma plasma cells

Molecular Therapy Oncology(2025)10.1016/j.omton.2025.200964

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0DataRank · unranked

2 citations

Enze Liu, Anh Q. Le, Mahesh Lamsal, Jagannath Misra, Sankalp Srivastava +9 more

Caloric Restriction Enhances the Efficacy of Antiandrogen Therapy in Prostate Cancer by Inhibiting Androgen Receptor Translation

Cancer Research(2025)10.1158/0008-5472.can-24-1986

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0DataRank · unranked

2 citations

May Elbanna, Christopher Rupert, Sabrina Orsi, Noah R. Sommers, Angela J. Klunk +11 more

Application of Whole Proteome Thermal Shift Assays to Define PERK-dependent Changes in Protein Homeostasis during the Unfolded Protein Response

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.08.647882

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0DataRank · unranked

2 citations

Sarah A. Peck Justice, Whitney R. Smith-Kinnaman, HR Sagara Wijeratne, Avery M. Runnebohm, Stéphane Pelletier +4 more

A three-stage assembly program governing pancreatic, plasma, pituitary, and bone secretory cell differentiation: A strategy to augment protein delivery

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110562

N/A

0DataRank · unranked

0 citations

Alexander G. Robling, Ronald C. Wek, Joseph P. Bidwell

Host sensing and signal transduction during Toxoplasma stage conversion

Molecular Microbiology(2020)10.1111/mmi.14634

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0DataRank · unranked

41 citations

Ronald C. Wek, William J. Sullivan, Leonardo Augusto

Cryo-EM reveals how ASX-173 inhibits human asparagine synthetase to activate the integrated stress response

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.16.682859

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0DataRank · unranked

0 citations

Nicholas T. Walda, Lucciano A. Pearce, Ronald C. Wek, Wen Zhu, Yuichiro Takagi +1 more