Michaela U. Gack

Also affiliated with Cleveland Clinic Florida, Vaccine & Gene Therapy Institute of Florida

Immunology and MicrobiologyBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 42 papers. Top paper: “RIG-I-like receptors: their regulation and roles in RNA sensing”.

RIG-I-like receptors: their regulation and roles in RNA sensing

Nature reviews. Immunology(2020)10.1038/s41577-020-0288-3

N/A

8.4DataRank · unranked

1672 citations

Michaela U. Gack, Jan Rehwinkel

Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV

PLOS Biology(2021)10.1371/journal.pbio.3001097

N/A

0.776DataRank · unranked

16 citations

Adrian Reich, Sadanandan E. Velu, Michaela U. Gack, Michiel van Gent

Virology under the Microscope—a Call for Rational Discourse

mSphere(2023)10.1128/msphere.00034-23

N/A

0.360DataRank · unranked

10 citations

Anice C. Lowen, Seema S. Lakdawala, James C. Alwine, Arturo Casadevall, Michael J. Imperiale +95 more

Virology under the Microscope—a Call for Rational Discourse

mBio(2023)10.1128/mbio.00188-23

N/A

0.241DataRank · unranked

4 citations

Anice C. Lowen, Seema S. Lakdawala, James C. Alwine, Arturo Casadevall, Michael J. Imperiale +95 more

A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19

ChemRxiv(2020)10.26434/chemrxiv.12579137.v1

N/A

0DataRank · unranked

19 citations

Yuan Hou, Jiayu Shen, Asha Kalianpur, Joe Zein, Daniel A. Culver +13 more

Fixed single-cell RNA sequencing for understanding virus infection and host response

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.17.302232

N/A

0DataRank · unranked

6 citations

Michiel van Gent, Nir Drayman, Anindita Basu, Michaela U. Gack, Savaş Tay +1 more

Multimodal Single-Cell Omics Analysis of COVID-19 Sex Differences in Human Immune Systems

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.01.407007

N/A

0DataRank · unranked

1 citations

Yadi Zhou, Michaela U. Gack, Justin D. Lathia, Asha Kallianpur, Reena Mehra +6 more

ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity

Nature Microbiology(2021)10.1038/s41564-021-00884-1

N/A

0DataRank · unranked

327 citations

Jung‐Hyun Lee, Zachary M. Parker, Dhiraj Acharya, Jessica J. Chiang, Michiel van Gent +6 more

High-throughput RNA sequencing of paraformaldehyde-fixed single cells

Nature Communications(2021)10.1038/s41467-021-25871-2

N/A

0DataRank · unranked

75 citations

Michiel van Gent, Nir Drayman, Anindita Basu, Michaela U. Gack, Savaş Tay +1 more

Multimodal single-cell omics analysis identifies epithelium–immune cell interactions and immune vulnerability associated with sex differences in COVID-19

Signal Transduction and Targeted Therapy(2021)10.1038/s41392-021-00709-x

N/A

0DataRank · unranked

30 citations

Yadi Zhou, Michaela U. Gack, Justin D. Lathia, Asha Kallianpur, Reena Mehra +6 more

The herpesvirus accessory protein γ134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I

PLoS Pathogens(2021)10.1371/journal.ppat.1009446

N/A

0DataRank · unranked

28 citations

Yijie Ma, Kathleen Voss, Michiel van Gent, Ying Chan, Michaela U. Gack +3 more

The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability

mBio(2021)10.1128/mbio.00620-21

N/A

0DataRank · unranked

28 citations

Steve Dvorkin, Jessica J. Chiang, Rachel B. Potter, Michaela U. Gack, Cindy Chiang

The BRCA1 Pseudogene Negatively Regulates Antitumor Responses through Inhibition of Innate Immune Defense Mechanisms

Cancer Research(2021)10.1158/0008-5472.can-20-1959

N/A

0DataRank · unranked

16 citations

Jing Zhang, Jung‐Hyun Lee, Jennifer M. Mason, Olga Karginova, Toshio F. Yoshimatsu +8 more

Actin cytoskeleton remodeling primes RIG-I-like receptor activation

Cell(2022)10.1016/j.cell.2022.08.011

N/A

0DataRank · unranked

77 citations

Rebecca Reis, Meta Volčič, Guanqun Liu, May K. Wang, Bing Shao Chia +7 more

GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141

Science Immunology(2022)10.1126/sciimmunol.abq4531

N/A

0DataRank · unranked

37 citations

Santoshi Muppala, Dhiraj Acharya, Josephine Nemegeer, Delfien Bogaert, Jung‐Hyun Lee +16 more

Insights into pandemic respiratory viruses: manipulation of the antiviral interferon response by SARS-CoV-2 and influenza A virus

Current Opinion in Immunology(2022)10.1016/j.coi.2022.102252

N/A

0DataRank · unranked

13 citations

Michaela U. Gack, Guanqun Liu

An Optimized Circular Polymerase Extension Reaction-based Method for Functional Analysis of SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.26.518005

N/A

0DataRank · unranked

3 citations

Michaela U. Gack, Guanqun Liu

Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation

Nature(2023)10.1038/s41586-023-05697-2

N/A

0DataRank · unranked

131 citations

Chue Vin Chin, Devin Kenney, Alexander H. Tavares, Nazimuddin Khan, Hasahn L. Conway +19 more

ISG15: its roles in SARS-CoV-2 and other viral infections

Trends in Microbiology(2023)10.1016/j.tim.2023.07.006

N/A

0DataRank · unranked

50 citations

Guanqun Liu, Michaela U. Gack, Lucky Sarkar

Viral evasion of the interferon response at a glance

Journal of Cell Science(2023)10.1242/jcs.260682

N/A

0DataRank · unranked

39 citations

Cindy Chiang, Michaela U. Gack, Junji Zhu

Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer

Nature Communications(2023)10.1038/s41467-023-39780-z

N/A

0DataRank · unranked

30 citations

Guanqun Liu, Lijia Jia, Eliza A. Ruben, Digant Nayak, Zuberwasim Sayyad +10 more

The RNA polymerase III–RIG-I axis in antiviral immunity and inflammation

Trends in Immunology(2023)10.1016/j.it.2023.04.002

N/A

0DataRank · unranked

29 citations

Filomeen Haerynck, Michaela U. Gack, Leslie Naesens

Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication

Cell Host & Microbe(2023)10.1016/j.chom.2023.06.013

N/A

0DataRank · unranked

27 citations

Cindy Chiang, Guanqun Liu, Zuberwasim Sayyad, Shanti Pandey, Meta Volčič +8 more

An optimized circular polymerase extension reaction-based method for functional analysis of SARS-CoV-2

Virology Journal(2023)10.1186/s12985-023-02025-y

N/A

0DataRank · unranked

23 citations

Michaela U. Gack, Guanqun Liu

CSNK2 suppresses autophagy by activating FLN-NHL-containing TRIM proteins

Autophagy(2023)10.1080/15548627.2023.2281128

N/A

0DataRank · unranked

23 citations

Lennart Koepke, Dhiraj Acharya, Victoria Hunszinger, Dennis Freisem, Alexander Grenzner +5 more

A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon

Nature Communications(2023)10.1038/s41467-023-39091-3

N/A

0DataRank · unranked

16 citations

Fulvia Terenzi, Guanqun Liu, Prabar K. Ghosh, Fengchun Ye, Kien Nguyen +12 more

Virology under the Microscope—a Call for Rational Discourse

Journal of Virology(2023)10.1128/jvi.00089-23

N/A

0DataRank · unranked

20 citations

Anice C. Lowen, Seema S. Lakdawala, James C. Alwine, Arturo Casadevall, Michael J. Imperiale +95 more

Data from The BRCA1 Pseudogene Negatively Regulates Antitumor Responses through Inhibition of Innate Immune Defense Mechanisms

(2023)10.1158/0008-5472.c.6513133.v1

N/A

0DataRank · unranked

0 citations

Jing Zhang, Jung Hyun Lee, Jennifer M. Mason, Olga Karginova, Toshio F. Yoshimatsu +8 more

Atypical activation of the RNA sensor MDA5 by hepatitis C virus

FEBS Journal(2023)10.1111/febs.17026

N/A

0DataRank · unranked

0 citations

Junji Zhu, Michaela U. Gack, Surajit Chakraborty

Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans

Nature Communications(2024)10.1038/s41467-024-49066-7

N/A

0DataRank · unranked

26 citations

Shoichiro Ando, Joe A. Holley, Atsushi Sugie, Fang Zhao, Subhajit Poddar +35 more

ISGylation of the SARS-CoV-2 N protein by HERC5 impedes N oligomerization and thereby viral RNA synthesis

Journal of Virology(2024)10.1128/jvi.00869-24

N/A

0DataRank · unranked

20 citations

Guanqun Liu, Zuberwasim Sayyad, Christopher M. Goins, Shaun R. Stauffer, Michaela U. Gack +1 more

ADAM9 promotes type I interferon-mediated innate immunity during encephalomyocarditis virus infection

Nature Communications(2024)10.1038/s41467-024-48524-6

N/A

0DataRank · unranked

16 citations

Junji Zhu, Michael R. King, Guanqun Liu, Zhiru Guo, Christopher R. MacKay +13 more

TRIM Proteins: Key Regulators of Immunity to Herpesvirus Infection

Viruses(2024)10.3390/v16111738

N/A

0DataRank · unranked

7 citations

Dhiraj Acharya, Michaela U. Gack, Zuberwasim Sayyad

HOIL1 mediates MDA5 activation through ubiquitination of LGP2

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.02.587772

N/A

0DataRank · unranked

3 citations

Junji Zhu, Guanqun Liu, Michaela U. Gack, Donna A. MacDuff, Donghao Cheng

MDA5 ISGylation is crucial for immune signaling to control viral replication and pathogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.20.614144

N/A

0DataRank · unranked

2 citations

Guanqun Liu, Dhiraj Acharya, Junji Zhu, Zuberwasim Sayyad, Michaela U. Gack +1 more

The RIG-I-like receptor family of immune proteins

Molecular Cell(2025)10.1016/j.molcel.2025.09.008

N/A

0DataRank · unranked

19 citations

Michaela U. Gack, Mariska van Huizen

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense

Nature Communications(2025)10.1038/s41467-025-59338-5

N/A

0DataRank · unranked

12 citations

Zuberwasim Sayyad, Helene Hoenigsperger, Maximilian Hirschenberger, Matthew A. Zurenski, Kannan Balakrishnan +9 more

MDA5 ISGylation is crucial for immune signaling to control viral replication and pathogenesis

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2420190122

N/A

0DataRank · unranked

11 citations

Guanqun Liu, Dhiraj Acharya, Junji Zhu, Zuberwasim Sayyad, Michaela U. Gack +1 more

Inhibition of coronaviral exonuclease activity by TRIM-mediated SUMOylation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.28.667286

N/A

0DataRank · unranked

2 citations

Surajit Chakraborty, Cindy Chiang, Caleb M. Stratton, Anna A. Tumanova, Shaun K. Olsen +2 more

A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19

PLoS Biology(2020)10.1371/journal.pbio.3000970

N/A

0DataRank · unranked

186 citations

Yuan Hou, Jiayu Shen, Reena Mehra, Asha Kallianpur, Daniel A. Culver +13 more

ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.26.356048

N/A

0DataRank · unranked

35 citations

Jung‐Hyun Lee, Zachary M. Parker, Dhiraj Acharya, Jessica J. Chiang, Michiel van Gent +6 more

A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19

ChemRxiv(2020)10.26434/chemrxiv.12579137

N/A

0DataRank · unranked

30 citations

Yuan Hou, Jiayu Shen, Asha Kalianpur, Joe Zein, Daniel A. Culver +13 more