Werner J. Geldenhuys

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

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Indexed papers

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 37 papers. Top paper: “Bioenergetic restoration and neuroprotection after therapeutic targeting of mitoNEET: New mechanism of pioglitazone following traumatic brain injury”.

Bioenergetic restoration and neuroprotection after therapeutic targeting of mitoNEET: New mechanism of pioglitazone following traumatic brain injury

Experimental Neurology(2020)10.1016/j.expneurol.2020.113243

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59 citations

W. Brad Hubbard, Jignesh D. Pandya, Hemendra J. Vekaria, Werner J. Geldenhuys, Patrick G. Sullivan +1 more

Pyrvinium Pamoate Use in a B cell Acute Lymphoblastic Leukemia Model of the Bone Tumor Microenvironment

Pharmaceutical Research(2020)10.1007/s11095-020-2767-4

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13 citations

Debbie Piktel, Quincy A. Hathaway, Stephanie L. Rellick, Patrick Thomas, Pushkar Saralkar +5 more

Nanoparticle formulation and in vitro efficacy testing of the mitoNEET ligand NL-1 for drug delivery in a brain endothelial model of ischemic reperfusion-injury

International Journal of Pharmaceutics(2020)10.1016/j.ijpharm.2020.119090

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37 citations

Tasneem Arsiwala, Werner J. Geldenhuys, Pushkar Saralkar

Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG

American Journal of Physiology-Cell Physiology(2021)10.1152/ajpcell.00264.2020

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59 citations

David A. Stanton, Stephanie L. Rellick, Werner J. Geldenhuys, Emidio E. Pistilli, Hannah E. Wilson

Clinically relevant mitochondrial-targeted therapy improves chronic outcomes after traumatic brain injury

Brain(2021)10.1093/brain/awab341

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49 citations

Malinda L Spry, Jennifer L. Gooch, Amber Cloud, Hemendra J. Vekaria, S. B. Burden +6 more

Co-culture model of B-cell acute lymphoblastic leukemia recapitulates a transcription signature of chemotherapy-refractory minimal residual disease

Scientific Reports(2021)10.1038/s41598-021-95039-x

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40 citations

Gangqing Hu, Debra Piktel, Karen H. Martin, Werner J. Geldenhuys, Rajesh R. Nair +2 more

Loss of the redox mitochondrial protein mitoNEET leads to mitochondrial dysfunction in B-cell acute lymphoblastic leukemia

Free Radical Biology and Medicine(2021)10.1016/j.freeradbiomed.2021.09.003

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19 citations

Debbie Piktel, Javohn C. Moore, Stephanie L. Rellick, Ethan Meadows, Mark V. Pinti +5 more

The Mitochondrial mitoNEET Ligand NL-1 Is Protective in a Murine Model of Transient Cerebral Ischemic Stroke

Pharmaceutical Research(2021)10.1007/s11095-021-03046-4

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18 citations

Alexander Mdzinarishvili, Tasneem Arsiwala, Yoon‐Kwang Lee, Patrick G. Sullivan, Mark V. Pinti +10 more

Small-Molecule HSP27 Inhibitor Abolishes Androgen Receptors in Glioblastoma

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.0c01537

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16 citations

Cody M. Orahoske, Werner J. Geldenhuys, Asmita Bhattarai, Abboud Sabbagh, Viharika Bobba +7 more

Quinacrine-CASIN combination overcomes chemoresistance in human acute lymphoid leukemia

Nature Communications(2021)10.1038/s41467-021-27300-w

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12 citations

Srinivas Chatla, Qiqi Lin, Fabliha Ahmed Chowdhury, Werner J. Geldenhuys, Wei Du +1 more

Dual monoamine oxidase B and acetylcholine esterase inhibitors for treating movement and cognition deficits in a C. elegans model of Parkinson’s disease

Medicinal Chemistry Research(2021)10.1007/s00044-021-02720-x

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5 citations

Ahmed Shubbar, Werner J. Geldenhuys, Jacob R Boos

Pioglitazone administration restores a PPARG-dependent transcriptional network and ATP levels within skeletal muscles of mice implanted with patient-derived breast tumors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.04.463044

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0 citations

Hannah E. Wilson, Matthew Chapa, Jessica N. Link, Werner J. Geldenhuys, Emidio E. Pistilli +1 more

Targeting Oxidative Stress Involved in Endometriosis and Its Pain

Biomolecules(2022)10.3390/biom12081055

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141 citations

Taylor Fleshman, Werner J. Geldenhuys, Nalini Santanam, Lauren Clower

Crosstalk between adenosine receptors and CYP450-derived oxylipins in the modulation of cardiovascular, including coronary reactive hyperemic response

Pharmacology & Therapeutics(2022)10.1016/j.pharmthera.2022.108213

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31 citations

Ahmad Hanif, Werner J. Geldenhuys, Stephanie O. Agba, Mohammed A. Nayeem

Interphotoreceptor matrix proteoglycans IMPG1 and IMPG2 proteolyze in the SEA domain and reveal localization mutual dependency

Scientific Reports(2022)10.1038/s41598-022-19910-1

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17 citations

Chloe Coulter, Werner J. Geldenhuys, Scott Rhodes, Ezequiel M. Salido, Benjamin Mitchell

Structure and biological evaluation of Caenorhabditis elegans CISD-1/mitoNEET, a KLP-17 tail domain homologue, supports attenuation of paraquat-induced oxidative stress through a p38 MAPK-mediated antioxidant defense response

Advances in Redox Research(2022)10.1016/j.arres.2022.100048

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7 citations

Hanna N. Jandrain, Emi Hagiuda, Alexander T. Taguchi, Kazuya Hasegawa, Bailey L. Fedun +7 more

Rescue of a peroxisome proliferator activated receptor gamma gene network in muscle after growth of human breast tumour xenografts

JCSM Rapid Communications(2022)10.1002/rco2.69

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6 citations

Hannah E. Wilson, Matthew Chapa, Jessica N. Link, Kristin Lupinacci, Werner J. Geldenhuys +2 more

The Mitochondrial Protein MitoNEET as a Probe for the Allostery of Glutamate Dehydrogenase

Molecules(2022)10.3390/molecules27238314

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3 citations

Erica M. Johnson, Sarah Gisondi, Felicia M. Roland, Werner J. Geldenhuys, Michael A. Menze +2 more

Novel mitoNEET ligand NL-1 improves therapeutic outcomes in an aged rat model of cerebral ischemia/reperfusion injury

Experimental Neurology(2022)10.1016/j.expneurol.2022.114128

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10 citations

Pushkar Saralkar, Scott D. Saylor, Patrick G. Sullivan, Jason D. Huber, Werner J. Geldenhuys +1 more

Pitavastatin Is Anti-Leukemic in a Bone Marrow Microenvironment Model of B-Lineage Acute Lymphoblastic Leukemia

Cancers(2022)10.3390/cancers14112681

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2 citations

Rajesh R. Nair, Stephanie L. Rellick, Werner J. Geldenhuys, Karen H. Martin, Michael Craig +2 more

Novel mitoNEET ligand NL‐1 improves therapeutic outcomes in an aged rat model of cerebral ischemia/reperfusion injury

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r4620

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0 citations

Pushkar Saralkar, Werner J. Geldenhuys, Jason D. Huber, Aruvi Vijikumar

Chloroquine reduces neutrophil extracellular trap (NET) formation through inhibition of peptidyl arginine deiminase 4 (PAD4)

Clinical & Experimental Immunology(2023)10.1093/cei/uxad005

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40 citations

B Matthew Fagan, Pranav Murthy, Michael T. Lotze, Herbert J. Zeh, Lori A Hazlehurst +3 more

Cancer-associated somatic mutations in human phosphofructokinase-1 reveal a critical electrostatic interaction for allosteric regulation of enzyme activity

Biochemical Journal(2023)10.1042/bcj20230207

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14 citations

Heather L. Hansen, Madison P. Cooper, Jacob I. Miller, N. Sukumar, Werner J. Geldenhuys +3 more

Release of hepatic xanthine oxidase (XO) to the circulation is protective in intravascular hemolytic crisis

Redox Biology(2023)10.1016/j.redox.2023.102636

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14 citations

Evan DeVallance, Sara E. Lewis, Katherine C. Wood, Gowtham K. Annarapu, Mara Carreño +12 more

Development of a fluorescence screening assay for binding partners of the iron-sulfur mitochondrial protein mitoNEET

Bioorganic & Medicinal Chemistry Letters(2023)10.1016/j.bmcl.2023.129310

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3 citations

Sarah A. Starcovic, Michael A. Menze, Mary E. Konkle, Timothy E. Long, Lori Hazlehurst +4 more

Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response

Advances in pharmacology(2023)10.1016/bs.apha.2022.12.003

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6 citations

Werner J. Geldenhuys, Ahmad Hanif, Mohammed A. Nayeem

SOX71, A Biocompatible Succinyl Derivative of the Triarylmethyl Radical OX071 for In Vivo Quantitative Oxygen Mapping Using Electron Paramagnetic Resonance

Molecular Imaging and Biology(2023)10.1007/s11307-023-01869-8

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6 citations

Martin Poncelet, Navin Viswakarma, Gian Paolo Vallerini, Safa Hameed, Teresa D. Gluth +7 more

Chemotherapeutic Activity of Pitavastatin in Vincristine Resistant B-Cell Acute Lymphoblastic Leukemia

Cancers(2023)10.3390/cancers15030707

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4 citations

Javohn C. Moore, Sloan Nesbit, Samuel A. Sprowls, Michael Craig, Stephanie L. Rellick +7 more

Flash nanoprecipitation assisted self-assembly of ionizable lipid nanoparticles for nucleic acid delivery

Nanoscale(2024)10.1039/d4nr00278d

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23 citations

Krystal A. Hughes, William H. Pentz, Parinya Samart, Werner J. Geldenhuys, Sharan Bobbala +1 more

Targeting myeloperoxidase limits myeloid cell immunosuppression enhancing immune checkpoint therapy for pancreatic cancer

Cancer Immunology Immunotherapy(2024)10.1007/s00262-024-03647-z

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18 citations

Kaitlyn M. Landreth, Remi Nohoesu, Stell P. Santiago, Werner J. Geldenhuys, Brian A. Boone +2 more

Flash nanoprecipitation allows easy fabrication of pH-responsive acetalated dextran nanoparticles for intracellular release of payloads

Discover Nano(2024)10.1186/s11671-023-03947-w

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13 citations

Bishal Misra, Maryam Maghareh, Parinya Samart, Ethan Nguyen, Salik Hussain +3 more

Synthesis and evaluation of enzyme inhibition by novel TT01001 derivatives as monoamine oxidase B inhibitors

Bioorganic & Medicinal Chemistry Letters(2024)10.1016/j.bmcl.2024.130045

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2 citations

R. Kane, Jason D. Huber, Werner J. Geldenhuys, Matheus Barbosa Belchior

TLR7-Adjuvanted Ionizable Lipid Nanoparticles for mRNA Vaccine Delivery

The AAPS Journal(2025)10.1208/s12248-025-01073-2

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8 citations

Krystal A. Hughes, William H. Pentz, Morgan Surface, Werner J. Geldenhuys, Sharan Bobbala +1 more

The Astrocytic Zinc Transporter ZIP12 Is a Synaptic Protein That Contributes to Synaptic Zinc Levels in the Mouse Auditory Cortex

Journal of Neuroscience(2025)10.1523/jneurosci.2067-24.2025

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4 citations

Benjamin Mendelson, Philip T R Bender, Kaitlin Bainer, Rayli Ruby, Victoria Shifflett +5 more

Hydroxychloroquine reduces metastatic tumor burden in pancreatic adenocarcinoma through myeloperoxidase inhibition

Journal of Inflammation(2025)10.1186/s12950-025-00456-8

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4 citations

Pavan Rao, Quinn Hopen, Kaitlyn M. Landreth, Angisha Basnet, Werner J. Geldenhuys +3 more

Targeting TRPC channels for control of arthritis-induced bone erosion

Science Advances(2025)10.1126/sciadv.abm9843

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3 citations

Jamie L. McCall, Jinbin Tian, Jaepyo Jeon, Aidan Douglas, Kendall Tyler +12 more

Oleic Acid Integrated Acetalated Dextran Nanoparticles for Enhanced Chemotherapeutic Delivery to the Bone Marrow

ACS Applied Materials & Interfaces(2025)10.1021/acsami.5c16936

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1 citations

William H. Pentz, Bishal Misra, Morgan Surface, Werner J. Geldenhuys, Salik Hussain +2 more