Thomas R. Kleyman

Also affiliated with University of Pittsburgh, Renal Association, University School, Case Western Reserve University

Biochemistry, Genetics and Molecular BiologyNeuroscienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 46 papers. Top paper: “Validation of commercially available antibodies directed against subunits of the epithelial Na+ channel”.

Validation of commercially available antibodies directed against subunits of the epithelial Na+ channel

Physiological Reports(2023)10.14814/phy2.15554

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0.643DataRank · unranked

15 citations

Shujie Shi, Sarah Christine Whelan, Thomas R. Kleyman, Stephanie M. Mutchler

Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.011789

N/A

0.385DataRank · unranked

12 citations

Nicolás Montalbetti, Xueqi Wang, Brittney M. Rush, Allison L. Marciszyn, Catherine J. Baty +4 more

Role of paraoxonase 3 in regulating ENaC‐mediated Na+ transport in the distal nephron

The Journal of Physiology(2024)10.1113/jp285034

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0.241DataRank · unranked

4 citations

Sarah Christine Whelan, Allison L. Marciszyn, Jingxin Chen, Thomas R. Kleyman, Shujie Shi +1 more

An American Physiological Society cross-journal Call for Papers on “Inter-Organ Communication in Homeostasis and Disease”

American Journal of Physiology-Lung Cellular and Molecular Physiology(2021)10.1152/ajplung.00209.2021

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0DataRank · unranked

17 citations

Heddwen L. Brooks, Nigel W. Bunnett, Hilary A. Coller, Mark R. Frey, Bina Joe +8 more

L-WNK1 is required for BK channel activation in intercalated cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.26.428162

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0DataRank · unranked

4 citations

Rolando Carrisoza‐Gaytan, Mohammad M. Al‐bataineh, Allison L. Marciszyn, Lubika J. Nkashama, Jingxin Chen +9 more

Modeling oxidative injury response in human kidney organoids

Research Square(2021)10.21203/rs.3.rs-826877/v1

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0DataRank · unranked

0 citations

Thitinee Vanichapol, Eugenel B. Espiritu, Amanda E. Crunk, Emily Parasky, Michael D. McDaniels +11 more

Modeling oxidative injury response in human kidney organoids

Stem Cell Research & Therapy(2022)10.1186/s13287-022-02752-z

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0DataRank · unranked

32 citations

Thitinee Vanichapol, Eugenel B. Espiritu, Amanda E. Crunk, Emily Parasky, Michael D. McDaniels +11 more

The molecular chaperone GRP170 protects against ER stress and acute kidney injury in mice

JCI Insight(2022)10.1172/jci.insight.151869

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0DataRank · unranked

24 citations

Diep Nguyen, Dennis R. Clayton, Wily G. Ruiz, Stephanie M. Mutchler, Evan C. Ray +10 more

Functional characterization of ion channels expressed in kidney organoids derived from human induced pluripotent stem cells

American Journal of Physiology-Renal Physiology(2022)10.1152/ajprenal.00365.2021

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0DataRank · unranked

9 citations

Aneta Przepiorski, Shujie Shi, Shaohu Sheng, Catherine J. Baty, Joseph C. Maggiore +6 more

The Molecular Chaperone, GRP170, Protects Against Acute Kidney Injury and ER Stress in Mice

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r4334

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0DataRank · unranked

0 citations

Aidan W. Porter, Wily G. Ruiz, Dennis R. Clayton, Stephanie M. Mutchler, Evan C. Ray +9 more

The Role of MUC1 in Lactation‐Associated Bone Mineral Conservation

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3809

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0DataRank · unranked

0 citations

Mohammad M. Al‐bataineh, Tracey Lam, Carol C. Kinlough, Allison L. Marciszyn, Jenna Barbour +5 more

Specific Ablation of Jak2 from CD11c+ Cells Attenuates Salt‐Sensitive Hypertension through an ENaC‐Dependent Mechanism

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3654

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0DataRank · unranked

0 citations

Luul A. Aden, Ashley Pitzer, Fernando Elijovich, Cheryl L. Laffer, Suman Pakala +4 more

Localization and Functional Characterization of the Cannabinoid Receptor Type 1 (CB1R) in the Kidney

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.l7733

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0DataRank · unranked

0 citations

Ken Mackie, Thomas R. Kleyman, Lisa M. Satlin, Joshua L. Rein

Influence of MUC1 on trafficking of TRPV5 and TRPV6 and in vivo Ca 2+ homeostasis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.22.513333

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0DataRank · unranked

0 citations

Carol L. Kinlough, Allison L. Marciszyn, Tracey Lam, Lorena Ye, Kendrah Kidd +8 more

Eicosanoid-Regulated Myeloid ENaC and Isolevuglandin Formation in Human Salt-Sensitive Hypertension

Hypertension(2023)10.1161/hypertensionaha.123.21285

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0DataRank · unranked

22 citations

Ashley Pitzer Mutchler, Sydney Jamison, Cheryl L. Laffer, Fernando Elijovich, Mohammad Saleem +14 more

The epithelial sodium channel in inflammation and blood pressure modulation

Frontiers in Cardiovascular Medicine(2023)10.3389/fcvm.2023.1130148

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0DataRank · unranked

14 citations

Lale A. Ertuğlu, Sepiso K. Masenga, Thomas R. Kleyman, Annet Kirabo, Taseer Ahmad

Mice lacking γENaC palmitoylation sites maintain benzamil-sensitive Na+ transport despite reduced channel activity

JCI Insight(2023)10.1172/jci.insight.172051

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0DataRank · unranked

9 citations

Stephanie M. Mutchler, Shaohu Sheng, Natalie A. Cox, Evan C. Ray, Ossama B. Kashlan +8 more

Influence of glycoprotein MUC1 on trafficking of the Ca2+-selective ion channels, TRPV5 and TRPV6, and on in vivo calcium homeostasis

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.102925

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0DataRank · unranked

7 citations

Carol L. Kinlough, Allison L. Marciszyn, Tracey Lam, Lorena Ye, Kendrah Kidd +10 more

Extracellular intersubunit interactions modulate epithelial Na+ channel gating

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.102914

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0DataRank · unranked

6 citations

Xueqi Wang, Jingxin Chen, Shaohu Sheng, Thomas R. Kleyman, Lei Zhang

Lhs1 dependent ERAD is determined by transmembrane domain context

Biochemical Journal(2023)10.1042/bcj20230075

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0DataRank · unranked

5 citations

Abigail M. Keith, Emma M. Perrault, Hannah E. Vorndran, Alexa S. Jordahl, Megan E. Yates +12 more

Genome mining yields putative disease-associated ROMK variants with distinct defects

PLoS Genetics(2023)10.1371/journal.pgen.1011051

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0DataRank · unranked

5 citations

Srikant Sarangi, Erin M. McChesney, Shaohu Sheng, Jacob D. Durrant, Aidan W. Porter +4 more

Profound hyponatremia and dehydration: A case of cisplatin induced renal salt wasting syndrome

Physiological Reports(2023)10.14814/phy2.15617

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0DataRank · unranked

5 citations

Kiran Kuriakose, Anjana Chandrasekhara Pillai, T. D. Powell, Thomas R. Kleyman, Tissa Bijoy George

Genome mining yields new disease-associated ROMK variants with distinct defects

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.05.539609

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0DataRank · unranked

2 citations

Srikant Sarangi, Erin M. McChesney, Shaohu Sheng, Aidan W. Porter, Thomas R. Kleyman +3 more

PIEZO1 is a distal nephron mechanosensor and is required for flow-induced K+ secretion

Journal of Clinical Investigation(2024)10.1172/jci174806

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0DataRank · unranked

25 citations

Stephanie M. Mutchler, Francisco Carattino, Joanne Soong, Marianela G. Dalghi, Peng Wu +5 more

Myeloid-Specific JAK2 Contributes to Inflammation and Salt Sensitivity of Blood Pressure

Circulation Research(2024)10.1161/circresaha.124.323595

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0DataRank · unranked

16 citations

Luul A. Aden, Ashley Pitzer Mutchler, C. Basu, Lale A. Ertuğlu, Quanhu Sheng +23 more

Dietary sodium alters aldosterone's effect on renal sodium transporter expression and distal convoluted tubule remodelling

The Journal of Physiology(2024)10.1113/jp284041

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0DataRank · unranked

8 citations

Mahpara Hasan, Carolyn P. Murphy, Catherine J. Baty, Cary R. Boyd‐Shiwarski, Annet Kirabo +2 more

Excess dietary sodium restores electrolyte and water homeostasis caused by loss of the endoplasmic reticulum molecular chaperone, GRP170, in the mouse nephron

American Journal of Physiology-Renal Physiology(2024)10.1152/ajprenal.00192.2024

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0DataRank · unranked

6 citations

Hannah E. Vorndran, Allison L. Marciszyn, Stephanie M. Mutchler, Arohan R. Subramanya, Thomas R. Kleyman +4 more

Loss of the alpha subunit distal furin cleavage site blunts ENaC activation following Na+ restriction

The Journal of Physiology(2024)10.1113/jp286559

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0DataRank · unranked

5 citations

Shaohu Sheng, Natalie A. Cox, Kennedy Szekely, Allison L. Marciszyn, Tracey Lam +8 more

Epithelial Na+ Channels, Immune Cells, and Salt

Annual Review of Physiology(2024)10.1146/annurev-physiol-022724-105050

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0DataRank · unranked

6 citations

Sepiso K. Masenga, Thomas R. Kleyman, Annet Kirabo

Going with the flow: New insights regarding flow induced K + secretion in the distal nephron

Physiological Reports(2024)10.14814/phy2.70087

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0DataRank · unranked

5 citations

Andrew J. Nickerson, Gilles Crambert, Lisa M. Satlin, Thomas R. Kleyman, Samia Lasaad

Cystic fibrosis–related metabolic defects: crosstalk between ion channels and organs

Journal of Clinical Investigation(2024)10.1172/jci182329

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0DataRank · unranked

4 citations

Eric S. Goetzman, Thomas R. Kleyman, Sunder Sims‐Lucas

Expression and localization of the mechanosensitive/osmosensitive ion channel TMEM63B in the mouse urinary tract

Physiological Reports(2024)10.14814/phy2.16043

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0DataRank · unranked

4 citations

Ella DuRie, Wily G. Ruiz, Dennis R. Clayton, Nicolás Montalbetti, Stephanie B. Mutchler +6 more

Characterization of hyperactive mutations in the renal potassium channel ROMK uncovers unique effects on channel biogenesis and ion conductance

Molecular Biology of the Cell(2024)10.1091/mbc.e23-12-0494

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0DataRank · unranked

3 citations

Shaohu Sheng, Anupam Banerjee, Christopher J. Guerriero, Jingxin Chen, Xueqi Wang +7 more

Epithelial Na+Channels Function as Extracellular Sensors

Comprehensive physiology(2024)10.1002/cphy.c230015

N/A

0DataRank · unranked

12 citations

Xue‐Ping Wang, Shaohu Sheng, Thomas R. Kleyman, Ossama B. Kashlan

Excess dietary sodium partially restores salt and water homeostasis caused by loss of the endoplasmic reticulum molecular chaperone, GRP170, in the mouse nephron

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.13.575426

N/A

0DataRank · unranked

1 citations

Hannah E. Vorndran, Allison L. Marciszyn, Stephanie M. Mutchler, Arohan R. Subramanya, Thomas R. Kleyman +4 more

Proteolytic Cleavage of the ENaC γ Subunit – Impact Upon Na + and K + Handling

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.12.579964

N/A

0DataRank · unranked

0 citations

Andrew J. Nickerson, Shaohu Sheng, Rolando Carrisoza‐Gaytan, Tracey Lam, Allison L. Marciszyn +10 more

Myeloid Cell Glucocorticoid, Not Mineralocorticoid Receptor Signaling, Contributes to Salt-Sensitive Hypertension in Humans via Cortisol

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.10.598374

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0DataRank · unranked

0 citations

Mert Demirci, Kit Neikirk, Lale A. Ertuğlu, Jeanne Ishimwe, Ashley Mutchler +15 more

Expression and distribution of MUC1 in the developing and adult kidney

American Journal of Physiology-Renal Physiology(2024)10.1152/ajprenal.00206.2024

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0DataRank · unranked

0 citations

Jonathan Barasch, Syed I. A. Zaidi, Carlton M. Bates, Evan C. Ray, Thomas R. Kleyman +2 more

Population Health Management for Improving Kidney Health Outcomes

American Journal of Kidney Diseases(2025)10.1053/j.ajkd.2025.01.020

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0DataRank · unranked

2 citations

Jane O. Schell, Melanie R. Weltman, Linda-Marie Ustaris Lavenburg, Chethan Puttarajappa, Gary S. Fischer +2 more

Paraoxonase 3 regulates the pore-forming α subunit of the large-conductance K+ channel

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research(2025)10.1016/j.bbamcr.2025.119990

N/A

0DataRank · unranked

0 citations

Andrew J. Nickerson, Nicolás Montalbetti, Stephanie M. Mutchler, Marcelo D. Carattino, Thomas R. Kleyman +2 more

Canagliflozin Inhibits Electrogenic Na+ Transport in Mouse Cortical Collecting Duct Cells

Function(2025)10.1093/function/zqaf039

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0DataRank · unranked

0 citations

Wafaa N. Albalawy, Elynna B. Youm, Nicole A Joseph, Kennedy Szekely, Thomas R. Kleyman +3 more

The scaffold protein IQGAP1 regulates the epithelial Na+ channel

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110919

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0DataRank · unranked

0 citations

Shujie Shi, Samar Sayedyahossein, Zhigang Li, Francis J. Roushar, Thomas R. Kleyman +2 more

Intercalated cell BKα subunit is required for flow-induced K+ secretion

JCI Insight(2020)10.1172/jci.insight.130553

N/A

0DataRank · unranked

47 citations

Evan C. Ray, Daniel Flores, Allison L. Marciszyn, Peng Wu, Leah Liu +12 more

Resistance to doxorubicin‐induced proteinuria and proteolytic activation of ENaC in 129S2 / SvPas mice

Physiological Reports(2025)10.14814/phy2.70667

N/A

0DataRank · unranked

0 citations

Ivy Liu, Niloofar Momenzadeh, Kennedy Szekely, Allison L. Marciszyn, Tracey Lam +3 more

An American Physiological Society cross-journal Call for Papers on “Deconstructing Organs: Single-Cell Analyses, Decellularized Organs, Organoids, and Organ-on-a-Chip Models”

American Journal of Physiology-Lung Cellular and Molecular Physiology(2020)10.1152/ajplung.00311.2020

N/A

0DataRank · unranked

11 citations

P. Darwin Bell, Sue C. Bodine, Heddwen L. Brooks, Nigel W. Bunnett, Bina Joe +9 more

Cleavage state of γENaC in mouse and rat kidneys

American Journal of Physiology-Renal Physiology(2021)10.1152/ajprenal.00536.2020

N/A

0DataRank · unranked

26 citations

Shujie Shi, Thomas R. Kleyman, Lawrence G. Palmer, Gustavo Frindt