R. Benjamin Free

Also affiliated with National Institute of Neurological Disorders and Stroke

Biochemistry, Genetics and Molecular BiologyNeuroscienceComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 16 papers. Top paper: “A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity”.

A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity

Science Signaling(2020)10.1126/scisignal.aaw5885

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0DataRank · unranked

47 citations

Ravi Kumar Verma, Blair K. A. Willette, Elizabeth C. Gonye, Annah M. Moore, Amy E. Moritz +6 more

Evidence for a Stereoselective Mechanism for Bitopic Activity by Extended-Length Antagonists of the D3 Dopamine Receptor

ACS Chemical Neuroscience(2020)10.1021/acschemneuro.0c00425

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0DataRank · unranked

15 citations

Alessandro Bonifazi, Adrian M. Guerrero, Vivek Kumar, R. Benjamin Free, J. Robert Lane +5 more

Ligand with Two Modes of Interaction with the Dopamine D2 Receptor–An Induced-Fit Mechanism of Insurmountable Antagonism

ACS Chemical Neuroscience(2020)10.1021/acschemneuro.0c00477

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0DataRank · unranked

13 citations

Hugo Zeberg, Tomasz Maciej Stępniewski, R. Benjamin Free, Sean W. Reilly, Robert R. Luedtke +8 more

Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D3 Dopamine Receptor Agonist

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00424

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0DataRank · unranked

25 citations

R. Benjamin Free, Warren S. Weiner, Emmanuel Akano, Disha M. Gandhi, Ara M. Abramyan +10 more

Development of pyrimidone D1 dopamine receptor positive allosteric modulators

Bioorganic & Medicinal Chemistry Letters(2020)10.1016/j.bmcl.2020.127696

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0DataRank · unranked

8 citations

Prashi Jain, R. Benjamin Free, Jennie Conroy, Jeffrey Aubé, David R. Sibley +2 more

Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors

Translational Psychiatry(2021)10.1038/s41398-020-01171-z

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94 citations

Suzanne Bertera, Marta Sánchez‐Soto, R. Benjamin Free, Jeongkyung Lee, Wei Zong +11 more

Pharmacological Characterization of the Imipridone Anticancer Drug ONC201 Reveals a Negative Allosteric Mechanism of Action at the D2 Dopamine Receptor

Molecular Pharmacology(2021)10.1124/molpharm.121.000336

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0DataRank · unranked

40 citations

Caroline A. Cuoco, Bing Xie, Yoon Namkung, Varun V. Prabhu, Blair K. A. Willette +8 more

Novel Cryo-EM structures of the D1 dopamine receptor unlock its therapeutic potential

Signal Transduction and Targeted Therapy(2021)10.1038/s41392-021-00630-3

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14 citations

Kathryn D. Luderman, R. Benjamin Free, Lei Shi, David R. Sibley

Dual pancreatic adrenergic and dopaminergic signaling as a therapeutic target of bromocriptine

iScience(2022)10.1016/j.isci.2022.104771

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0DataRank · unranked

20 citations

Suzanne Bertera, Laura Friggeri, Marta Sánchez‐Soto, Jeongkyung Lee, Xiangning Xue +10 more

Identification and Characterization of ML321: A Novel and Highly Selective D 2 Dopamine Receptor Antagonist with Efficacy in Animal Models That Predict Atypical Antipsychotic Activity

ACS Pharmacology & Translational Science(2022)10.1021/acsptsci.2c00202

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0DataRank · unranked

5 citations

Ashley N. Nilson, Noelia Boldizsar, Trevor Doyle, Ramona M. Rodriguiz, Vladimir M. Pogorelov +14 more

Novel Dopamine D4 Receptor‐Selective Antagonists For Neuropsychiatric Disorders

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5298

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0DataRank · unranked

0 citations

Shreya Kelshikar, Nisha K. Shah, Connor McBride, Moises Ximello Sanchez, Diandra Panasis +11 more

Identification and Characterization of ML321: a Novel and Highly Selective D 2 Dopamine Receptor Antagonist with Efficacy in Animal Models that Predict Atypical Antipsychotic Activity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.14.516475

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0DataRank · unranked

0 citations

Ashley N. Nilson, Noelia Boldizsar, Trevor Doyle, Ramona M. Rodriguiz, Vladimir M. Pogorelov +14 more

G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation

Biomolecules(2023)10.3390/biom13101552

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0DataRank · unranked

14 citations

Noelia Boldizsar, Kayla A. Schardien, Nora S. Madaras, Blair K. A. Willette, Laura R. Inbody +8 more

Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00734

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0DataRank · unranked

10 citations

Ashley N. Nilson, Rebekah Placide, Mimi L. Pham, Franziska M. Jakobs, Noelia Boldizsar +30 more

Bioisosteric Replacement of Amides Linkers with 1, 2, 3-Triazoles for Improved Pharmacokinetics Without Losing Dopamine D4 Receptor Potency or Selectivity

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.261980

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0DataRank · unranked

0 citations

Mohammad Alkhatib, Julianna Saez, J. B. Hanson, Ashley N. Nilson, Franziska M. Jacobs +10 more

Discovery, Characterization, and Optimization of a Novel Positive Allosteric Modulator-Antagonist of the D3 Dopamine Receptor

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01585

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0DataRank · unranked

1 citations

Feijun Wang, Nora S. Madaras, Amber M. Kelley, Kirsten K. Snyder, Disha M. Gandhi +8 more