Ornit Chiba‐Falek

Also affiliated with Duke Medical Center, Duke University Hospital

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.183Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The APOE-TOMM40 Humanized Mouse Model: Characterization of Age, Sex, and PolyT Variant Effects on Gene Expression

Journal of Alzheimer s Disease(2023)10.3233/jad-230451

Top 66%

0.183DataRank

Top 66%2 citations

Scott Mahon, Dellila Hodgson, Julio Barrera, Delaney Hill, Angela Wei +7 more

Papers

Driven by 29 papers — median percentile 34. Top paper: “Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference”.

Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference

Alzheimer s & Dementia(2024)10.1002/alz.13877

N/A

1.1DataRank · unranked

33 citations

Michaël E. Belloy, Elizabeth Blue, Gregory R. Bowman, María C. Carrillo, Xiaoying Chen +55 more

Shared genetic etiology underlying Alzheimer’s disease and major depressive disorder

Translational Psychiatry(2020)10.1038/s41398-020-0769-y

N/A

0.663DataRank · unranked

82 citations

Daniel Sprague, Julio Barrera, Ornit Chiba‐Falek, Michael W. Lutz

Gene-Editing Technologies Paired With Viral Vectors for Translational Research Into Neurodegenerative Diseases

Frontiers in Molecular Neuroscience(2020)10.3389/fnmol.2020.00148

N/A

0.593DataRank · unranked

51 citations

Malik Moncalvo, Ornit Chiba‐Falek, Boris Kantor, Joseph E. Rittiner

Polygenic Risk Score Effectively Predicts Depression Onset in Alzheimer’s Disease Based on Major Depressive Disorder Risk Variants

Frontiers in Neuroscience(2022)10.3389/fnins.2022.827447

N/A

0.564DataRank · unranked

16 citations

Hongliang Liu, Sheng Luo, Michael W. Lutz, Ornit Chiba‐Falek, Suraj Upadhya

Trends and challenges of AAV-delivered gene editing therapeutics for CNS disorders: Implications for neurodegenerative disease

Molecular Therapy — Nucleic Acids(2025)10.1016/j.omtn.2025.102635

N/A

0.559DataRank · unranked

20 citations

Bernadette O’Donovan, Ornit Chiba‐Falek, Boris Kantor

Infection and inflammation: New perspectives on Alzheimer's disease

Brain Behavior & Immunity - Health(2022)10.1016/j.bbih.2022.100462

N/A

0.538DataRank · unranked

35 citations

Carol A. Colton, Joseph El Khoury, David Gate, Alison Goate, Michael T. Heneka +19 more

The therapeutic implications of all-in-one AAV-delivered epigenome-editing platform in neurodegenerative disorders

Nature Communications(2024)10.1038/s41467-024-50515-6

N/A

0.524DataRank · unranked

32 citations

Bernadette O’Donovan, Joseph E. Rittiner, Dellila Hodgson, Nicholas Lindner, Sophia Guerrero +4 more

Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics

Neuropsychopharmacology(2021)10.1038/s41386-021-01023-4

N/A

0.489DataRank · unranked

25 citations

Chia‐Yen Chen, Tian Ge, Yan Xia, David W. Hill, Joey W. Trampush +66 more

Neuronal-type-specific epigenome editing to decrease SNCA expression: Implications for precision medicine in synucleinopathies

Molecular Therapy — Nucleic Acids(2023)10.1016/j.omtn.2023.102084

N/A

0.457DataRank · unranked

20 citations

Boris Kantor, Ornit Chiba‐Falek, Zhiguo Sun

Bioinformatics pipeline to guide late‐onset Alzheimer's disease (LOAD) post‐GWAS studies: Prioritizing transcription regulatory variants within LOAD‐associated regions

Alzheimer s & Dementia Translational Research & Clinical Interventions(2022)10.1002/trc2.12244

N/A

0.434DataRank · unranked

17 citations

Ornit Chiba‐Falek, Michael W. Lutz

Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer’s disease brains

Molecular Neurodegeneration(2021)10.1186/s13024-021-00481-0

N/A

0.406DataRank · unranked

14 citations

Lingyun Song, Julia Gamache, Melanie E. Garrett, Alexias Safi, Young Won Yun +11 more

APOE-Targeted Therapeutics for Alzheimer's Disease

Journal of Neuroscience(2025)10.1523/jneurosci.1388-25.2025

N/A

0.338DataRank · unranked

8 citations

Cristelle Hugo, Bernadette O’Donovan, Isaiah O. Stephens, Lance A. Johnson, Gregory M. Cole +5 more

Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.06.934752

N/A

0.312DataRank · unranked

7 citations

Chen Chia-Yen, Xia Yan, W. David Hill, Joey W. Trampush, Jin Yu +64 more

Differential Gene Expression and DNA Methylation in the Risk of Depression in LOAD Patients

Biomolecules(2022)10.3390/biom12111679

N/A

0.312DataRank · unranked

7 citations

Daniel Oliveros Gingerich, Michael W. Lutz, Ornit Chiba‐Falek, Suraj Upadhya

The APOE-TOMM40 Humanized Mouse Model: Characterization of Age, Sex, and PolyT Variant Effects on Gene Expression

Journal of Alzheimer s Disease(2023)10.3233/jad-230451

Top 66%

0.183DataRank

Top 66%2 citations

Scott Mahon, Dellila Hodgson, Julio Barrera, Delaney Hill, Angela Wei +7 more

Single cell transcriptomics reveals enrichment of aggregation-prone alpha-synuclein isoforms across synucleinopathies

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.13.682119

N/A

0DataRank · unranked

0 citations

Webb Pierson, Daniel Oliveros Gingerich, Zhaohui Man, Sapir Margalit, Dean Yona +8 more

The mechanistic role of alpha-synuclein in the nucleus: impaired nuclear function caused by familial Parkinson’s disease SNCA mutations

Human Molecular Genetics(2020)10.1093/hmg/ddaa183

N/A

0DataRank · unranked

76 citations

Malik Moncalvo, Dominic Tringali, Lidia Tagliafierro, Ahila Shriskanda, Ekaterina Ilich +4 more

Phenotypic regional fMRI activation patterns during memory encoding in MCI and AD

UNC Libraries(2020)10.17615/h6cx-5d82

N/A

0DataRank · unranked

0 citations

Karen A. Tucker, Jeffrey N. Browndyke, James R. Burke, Kathleen A. Welsh‐Bohmer, Ornit Chiba‐Falek +3 more

APOE: The New Frontier in the Development of a Therapeutic Target towards Precision Medicine in Late-Onset Alzheimer’s

International Journal of Molecular Sciences(2021)10.3390/ijms22031244

N/A

0DataRank · unranked

48 citations

Boris Kantor, Ornit Chiba‐Falek, Anna Yang

Cell-Type Specific Changes in DNA Methylation of SNCA Intron 1 in Synucleinopathy Brains

Frontiers in Neuroscience(2021)10.3389/fnins.2021.652226

N/A

0DataRank · unranked

30 citations

Julio Barrera, Young Won Yun, Susan K. Murphy, Thomas G. Beach, Randy Woltjer +4 more

The Path to Progress Preclinical Studies of Age-Related Neurodegenerative Diseases: A Perspective on Rodent and hiPSC-Derived Models

Molecular Therapy(2021)10.1016/j.ymthe.2021.01.001

N/A

0DataRank · unranked

26 citations

Logan Y. Brown, Boris Kantor, Ornit Chiba‐Falek, Gabriella MacDougall

Polygenic Risk Score Effectively Predicts Risk of Depression Onset in Alzheimer’s Disease

Research Square(2021)10.21203/rs.3.rs-845772/v1

N/A

0DataRank · unranked

0 citations

Hongliang Liu, Sheng Luo, Michael W. Lutz, Ornit Chiba‐Falek, Suraj Upadhya

Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer’s disease brains

Cell & Bioscience(2023)10.1186/s13578-023-01120-5

N/A

0DataRank · unranked

23 citations

Daniel Gingerich, E. Keats Shwab, Julio Barrera, Melanie E. Garrett, Cordelia Hume +4 more

Bioinformatics pipeline to guide post‐GWAS studies in Alzheimer's: A new catalogue of disease candidate short structural variants

Alzheimer s & Dementia(2023)10.1002/alz.13168

N/A

0DataRank · unranked

4 citations

Ornit Chiba‐Falek, Michael W. Lutz

Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer’s disease brains

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.12.540037

N/A

0DataRank · unranked

0 citations

Daniel Gingerich, E. Keats Shwab, Julio Barrera, Melanie E. Garrett, Cordelia Hume +4 more

Comparative mapping of single-cell transcriptomic landscapes in neurodegenerative diseases

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.13.628436

N/A

0DataRank · unranked

4 citations

Zhaohui Man, Daniel Oliveros Gingerich, Julia Gamache, Melanie E. Garrett, Geidy E. Serrano +5 more

Microglia States are Susceptible to Senescence and Cholesterol Dysregulation in Alzheimer’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.11.18.624141

N/A

0DataRank · unranked

3 citations

Shaowei Wang, Bilal E. Kerman, Cristelle Hugo, E. Keats Shwab, Chang Shu +4 more

Leveraging multiomic approaches to elucidate mechanisms of heterogeneity in Alzheimer's disease: Neuropsychiatric symptoms, co‐pathologies, and sex differences

Alzheimer s & Dementia(2025)10.1002/alz.70549

N/A

0DataRank · unranked

8 citations

Gita A. Pathak, Joshua Harvey, Michaël E. Belloy, Corinne E. Fischer, Michael W. Lutz +11 more

Sex-dependent effect of APOE on Alzheimer's disease and other age-related neurodegenerative disorders

Disease Models & Mechanisms(2020)10.1242/dmm.045211

N/A

0DataRank · unranked

86 citations

Young Won Yun, Ornit Chiba‐Falek, Julia Gamache

Ornit Chiba‐Falek

Indexed papers

Top data-sharing exemplar

Papers