Rudolf Jaenisch

Whitehead Institute for Biomedical Research

Also affiliated with Massachusetts Institute of Technology

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 55 papers. Top paper: “Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells”.

Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells

Cell(1986)10.1016/0092-8674(86)90596-9

N/A

13.6DataRank · unranked

230 citations

Richard C. Mulligan, Rudolf Jaenisch, Eric Barklis

Genome-scale DNA methylation maps of pluripotent and differentiated cells

Nature(2008)10.1038/nature07107

N/A

1.2DataRank · unranked

2535 citations

Tarjei S. Mikkelsen, Hongcang Gu, Marius Wernig, Sachet A. Shukla, Xiaolan Zhang +8 more

In situ genome sequencing resolves DNA sequence and structure in intact biological samples

Science(2021)10.1126/science.aay3446

N/A

0.805DataRank · unranked

213 citations

Zachary Chiang, Paul Reginato, Sarah Mangiameli, Evan Murray, Chun‐Chen Yao +9 more

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation

Genes & Development(2014)10.1101/gad.246819.114

N/A

0.716DataRank · unranked

117 citations

Samuel G. Regalado, Christine S. Lai, Gregory J. Cost, Colleen M. O’Neil, Fyodor D. Urnov +5 more

Reconstruction of developmental landscapes by optimal-transport analysis of single-cell gene expression sheds light on cellular reprogramming

bioRxiv (Cold Spring Harbor Laboratory)(2017)10.1101/191056

N/A

0.533DataRank · unranked

34 citations

Jian Shu, Marcin Tabaka, Brian Cleary, Vidya Subramanian, Aryeh Solomon +12 more

Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction

Cell Reports Medicine(2020)10.1016/j.xcrm.2020.100097

N/A

0.515DataRank · unranked

30 citations

Jacob Jeppesen, Rudolf Jaenisch, Haiting Ma

SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection

Nature Communications(2024)10.1038/s41467-024-54917-4

N/A

0.283DataRank · unranked

4 citations

Andrew Khalil, Max Friesen, Troy W. Whitfield, Xinlei Gao, Tenzin Lungjangwa +6 more

Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.25.605098

N/A

0.269DataRank · unranked

5 citations

Kathrin M Kajderowicz, Heather R. Keys, Julian Roessler, Evgeni M. Frenkel, Adina Kirkland +8 more

Multiplex Epigenome Editing of MECP2 to Rescue Rett Syndrome Neurons

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.30.518560

N/A

0.165DataRank · unranked

2 citations

Xiaonan Guan, Bing Xie, Chuanyun Xu, Jacqueline Niu, Xin Tang +5 more

OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human

Nature Communications(2021)10.1038/s41467-021-25107-3

N/A

0DataRank · unranked

38 citations

Kyoung‐mi Park, Paul Gontarz, Bo Zhang, Joshua Pan, Zachary M. McKenzie +19 more

16pdel lipid changes in iPSC-derived neurons and function of FAM57B in lipid metabolism and synaptogenesis

iScience(2021)10.1016/j.isci.2021.103551

N/A

0DataRank · unranked

27 citations

Jiyoon L. Kim, Yara Khodour, Jasmine M. McCammon, Maya Mitalipova, Rudolf Jaenisch +3 more

Cell lineage as a predictor of immune response in neuroblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.29.428154

N/A

0DataRank · unranked

8 citations

Sanjukta Das, Ângela C. Crespo, Brian C. Miller, Bandana Sharma, Shupei Zhang +12 more

FAM57B is a modulator of ceramide synthesis that regulates sphingolipid homeostasis and synaptic composition in the developing brain

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.02.433619

N/A

0DataRank · unranked

2 citations

Jiyoon L. Kim, Yara Khodour, Jasmine M. McCammon, Maya Mitalipova, Rudolf Jaenisch +3 more

Autophagy promotes cell survival by maintaining NAD(H) levels

Research Square(2021)10.21203/rs.3.rs-659023/v1

N/A

0DataRank · unranked

0 citations

Tetsushi Kataura, Elena Seranova, Congxin Sun, Elsje G. Otten, Malkiel A. Cohen +41 more

Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes

Nature Cancer(2022)10.1038/s43018-022-00427-5

N/A

0DataRank · unranked

90 citations

Sanjukta Das, Ângela C. Crespo, Annelisa M. Cornel, Anand G. Patel, Navin R. Mahadevan +24 more

Autophagy promotes cell survival by maintaining NAD levels

Developmental Cell(2022)10.1016/j.devcel.2022.10.008

N/A

0DataRank · unranked

75 citations

Lucia Sedlackova, Elsje G. Otten, Ruchika Kumari, David Shapira, Filippo Scialò +26 more

Tunable Conductive Hydrogel Scaffolds for Neural Cell Differentiation

Advanced Healthcare Materials(2022)10.1002/adhm.202202221

N/A

0DataRank · unranked

67 citations

Marjolaine Boulingre, Andrew Khalil, Tenzin Lungjangwa, Rudolf Jaenisch, Benjamin R. Freedman +1 more

Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell–derived alveolar epithelium

JCI Insight(2022)10.1172/jci.insight.155589

N/A

0DataRank · unranked

48 citations

Julio Sainz de Aja, Jonathan Lindstrom-Vautrin, Konstantinos–Dionysios Alysandratos, Alexsia Richards, Carolina García de Alba +12 more

The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance

Nature Communications(2022)10.1038/s41467-022-35176-7

N/A

0DataRank · unranked

47 citations

Jesse M. Platt, Ming Zheng, Max Friesen, Giuseppe Dall’Agnese, Alyssa M. Blaise +15 more

Development of a physiological insulin resistance model in human stem cell–derived adipocytes

Science Advances(2022)10.1126/sciadv.abn7298

N/A

0DataRank · unranked

21 citations

Andrew Khalil, M. Inmaculada Barrasa, Jacob Jeppesen, David Mooney, Rudolf Jaenisch +1 more

SARS-CoV-2 infection of human pluripotent stem cell-derived liver organoids reveals potential mechanisms of liver pathology

iScience(2022)10.1016/j.isci.2022.105146

N/A

0DataRank · unranked

17 citations

Max Friesen, Andrew Khalil, M. Inmaculada Barrasa, Lee Gehrke, Rudolf Jaenisch +1 more

Fragile X Syndrome Patient–Derived Neurons Developing in the Mouse Brain Show FMR1-Dependent Phenotypes

Biological Psychiatry(2022)10.1016/j.biopsych.2022.08.020

N/A

0DataRank · unranked

2 citations

Hao Wu, Bingbing Yuan, Troy W. Whitfield, X. Shawn Liu, Dongdong Fu +14 more

Rapid iPSC inclusionopathy models shed light on formation, consequence and molecular subtype of α-synuclein inclusions

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.08.515615

N/A

0DataRank · unranked

9 citations

Alain Ndayisaba, Amanda J. Lewis, YuHong Fu, Giselle T. Sagredo, Ludovica Zaccagnini +44 more

A nuclear receptor facilitates differentiation of human PSCs into more mature hepatocytes

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.24.485641

N/A

0DataRank · unranked

1 citations

Esmée de Zwaan, Yang Guo, Paloma Cejas, Prathapan Thiru, Martijn van de Bunt +12 more

Multiplex genome editing of human pluripotent stem cells using Cpf1

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.13.488123

N/A

0DataRank · unranked

1 citations

Rudolf Jaenisch, Haiting Ma

Multiplex epigenome editing of MECP2 to rescue Rett syndrome neurons

Science Translational Medicine(2023)10.1126/scitranslmed.add4666

N/A

0DataRank · unranked

95 citations

Xiaonan Guan, Bing Xie, Chuanyun Xu, Jacqueline Niu, Xin Tang +5 more

NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency

Cell Reports(2023)10.1016/j.celrep.2023.112372

N/A

0DataRank · unranked

43 citations

Elena Seranova, Malkiel A. Cohen, Miruna Chipara, Jennie Roberts, Dewi Astuti +35 more

LINE1-Mediated Reverse Transcription and Genomic Integration of SARS-CoV-2 mRNA Detected in Virus-Infected but Not in Viral mRNA-Transfected Cells

Viruses(2023)10.3390/v15030629

N/A

0DataRank · unranked

16 citations

Punam Bisht, Anthony Flamier, M. Inmaculada Barrasa, Max Friesen, Alexsia Richards +3 more

LINE1-mediated reverse transcription and genomic integration of SARS-CoV-2 mRNA detected in virus-infected but not in viral mRNA-transfected cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.10.527906

N/A

0DataRank · unranked

6 citations

Punam Bisht, Anthony Flamier, M. Inmaculada Barrasa, Alexsia Richards, Stephen H. Hughes +2 more

Human iPS cell-derived sensory neurons can be infected by SARS-CoV-2 strain WA1/2020 as well as variants delta and omicron

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.10.523422

N/A

0DataRank · unranked

3 citations

Punam Bisht, Alexsia Richards, Danielle L. Tomasello, Rudolf Jaenisch, Anthony Flamier

SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.06.552160

N/A

0DataRank · unranked

3 citations

Andrew Khalil, Max Friesen, Troy W. Whitfield, Xinlei Gao, Tenzin Lungjangwa +6 more

The A53T mutation in α-synuclein enhances pro-inflammatory activation in human microglia

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.29.555300

N/A

0DataRank · unranked

2 citations

Bingbing Yuan, Wenyu Chen, Tatsuya Osaki, Dongdong Fu, Carrie M. Garrett-Engele +5 more

Data from DNMT3B Expression Might Contribute to CpG Island Methylator Phenotype in Colorectal Cancer

(2023)10.1158/1078-0432.c.6517612

N/A

0DataRank · unranked

0 citations

Kaori Shima, Natsumi Irahara, Shoko Kure, Yoshifumi Baba, Gregory J. Kirkner +9 more

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons

Neuron(2024)10.1016/j.neuron.2024.04.007

N/A

0DataRank · unranked

57 citations

Anthony Flamier, George W. Bell, Annette J. Diao, Troy W. Whitfield, Hao‐Che Wang +10 more

Tuning porosity of macroporous hydrogels enables rapid rates of stress relaxation and promotes cell expansion and migration

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2410806121

N/A

0DataRank · unranked

55 citations

Kirti Kashyap, Brendan T. Deveney, Junzhe Lou, Blake F. Hanan, Qi Liu +9 more

Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions

Neuron(2024)10.1016/j.neuron.2024.06.002

N/A

0DataRank · unranked

31 citations

Alain Ndayisaba, Amanda J. Lewis, YuHong Fu, Giselle T. Sagredo, Anastasia Kuzkina +49 more

Mitochondrial dysfunction and increased reactive oxygen species production in MECP2 mutant astrocytes and their impact on neurons

Scientific Reports(2024)10.1038/s41598-024-71040-y

N/A

0DataRank · unranked

23 citations

M. Inmaculada Barrasa, David Mankus, Katia I Alarcon, Abigail K. R. Lytton‐Jean, X. Shawn Liu +2 more

The A53T Mutation in α-Synuclein Enhances Proinflammatory Activation in Human Microglia Upon Inflammatory Stimulus

Biological Psychiatry(2024)10.1016/j.biopsych.2024.07.011

N/A

0DataRank · unranked

18 citations

Bingbing Yuan, Wenyu Chen, Tatsuya Osaki, Dongdong Fu, Carrie M. Garrett-Engele +6 more

Abortive infection of bat fibroblasts with SARS-CoV-2

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2406773121

N/A

0DataRank · unranked

9 citations

Michael D. Gallagher, M. Inmaculada Barrasa, Julie Boucau, Alfred T. Harding, Marion Déjosez +8 more

Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes

Immunity(2024)10.1016/j.immuni.2024.07.019

N/A

0DataRank · unranked

8 citations

Felix Sümpelmann, Wentao Dong, Eshaan S. Rawat, Inés Fernández-Maestre, Dongdong Fu +17 more

Human-specific paralogs of SRGAP2 induce neotenic features of microglia structural and functional maturation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.28.601266

N/A

0DataRank · unranked

5 citations

Marine Krzisch, Juyoun Yoo, Patricia R. Nano, Aparna Bhaduri, Rudolf Jaenisch +2 more

Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death

eLife(2024)10.7554/elife.102310

N/A

0DataRank · unranked

0 citations

Kathrin M Kajderowicz, Heather R. Keys, Julian Roessler, Evgeni M. Frenkel, Adina Kirkland +8 more

Human iPSC‐Derived Microglia Integrate Into Cerebral Organoids and Assume an In Vivo‐Like Phenotype

European Journal of Neuroscience(2025)10.1111/ejn.70281

N/A

0DataRank · unranked

7 citations

Felix Sümpelmann, Andrew Khalil, Anthony Flamier, Dongdong Fu, George W. Bell +2 more

A human blood-brain barrier model reveals pericytes as critical regulators of viral neuroinvasion

iScience(2025)10.1016/j.isci.2025.114443

N/A

0DataRank · unranked

1 citations

Andrew Khalil, Punam Bisht, Troy W. Whitfield, Xinlei Gao, David Mooney +3 more

Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing

eLife(2025)10.7554/elife.107298

N/A

0DataRank · unranked

3 citations

Grayson O. Sipe, Xin Tang, Prachi Ojha, Giselle Fernandes, Yi Ning Leow +7 more

A novel human blood-brain barrier model reveals pericytes as critical regulators of viral neuroinvasion

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2024.12.18.629173

N/A

0DataRank · unranked

0 citations

Andrew Khalil, Punam Bisht, Troy W. Whitfield, Xinlei Gao, Roger D. Kamm +4 more

Human iPS cell-derived sensory neurons can be infected by SARS-CoV-2

iScience(2023)10.1016/j.isci.2023.107690

N/A

0DataRank · unranked

14 citations

Punam Bisht, Alexsia Richards, Danielle L. Tomasello, Rudolf Jaenisch, Anthony Flamier

MeCP2 links heterochromatin condensates and neurodevelopmental disease

Nature(2020)10.1038/s41586-020-2574-4

N/A

0DataRank · unranked

206 citations

Eliot L. Coffey, Alessandra Dall’Agnese, Nancy M. Hannett, Xin Tang, Jonathan E. Henninger +15 more

Engineered tissues and strategies to overcome challenges in drug development

Advanced Drug Delivery Reviews(2020)10.1016/j.addr.2020.09.012

N/A

0DataRank · unranked

72 citations

Rudolf Jaenisch, David Mooney, Andrew Khalil

Functional analysis of CX3CR1 in human induced pluripotent stem (iPS) cell‐derived microglia‐like cells

European Journal of Neuroscience(2020)10.1111/ejn.14879

N/A

0DataRank · unranked

40 citations

Maisam Mitalipova, Rudolf Jaenisch, Nobuhito Murai

Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

Cell stem cell(2020)10.1016/j.stem.2020.02.001

N/A

0DataRank · unranked

48 citations

Shupei Zhang, Satyaki Sengupta, Haiting Ma, George W. Bell, Brendan Horton +5 more

SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.12.422516

N/A

0DataRank · unranked

69 citations

Alexsia Richards, Andrew Khalil, Emile Wogram, Haiting Ma, Richard A. Young +2 more

Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2105968118

N/A

0DataRank · unranked

301 citations

Alexsia Richards, M. Inmaculada Barrasa, Stephen H. Hughes, Richard A. Young, Rudolf Jaenisch +1 more

Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing

Nature Communications(2021)10.1038/s41467-021-26097-y

N/A

0DataRank · unranked

145 citations

Styliani Markoulaki, Logan J. Blaine, Mitchell L. Leibowitz, Cheng‐Zhong Zhang, Rudolf Jaenisch +2 more

Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening

Cell Reports(2021)10.1016/j.celrep.2021.109233

N/A

0DataRank · unranked

67 citations

Kyoung‐mi Park, Laura A. Fischer, Chen Dong, Tenzin Lungjangwa, Marta Jiménez +7 more