Niraj H. Tolia

Also affiliated with National Institute of Allergy and Infectious Diseases, National Institute of Malaria Research

MedicineImmunology and MicrobiologyComputer ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 48 papers. Top paper: “Extraordinary Titer and Broad Anti-SARS-CoV-2 Neutralization Induced by Stabilized RBD Nanoparticles from Strain BA.5”.

Extraordinary Titer and Broad Anti-SARS-CoV-2 Neutralization Induced by Stabilized RBD Nanoparticles from Strain BA.5

Vaccines(2023)10.3390/vaccines12010037

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0.345DataRank · unranked

9 citations

Baoshan Zhang, Li Ou, Qi Qiu, Lingshu Wang, Tatsiana Bylund +18 more

Immunological characterization of a VIR protein family member (VIR-14) in Plasmodium vivax-infected subjects from different epidemiological regions in Africa and South America

PLoS neglected tropical diseases(2023)10.1371/journal.pntd.0011229

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0.295DataRank · unranked

3 citations

Camila H. Coelho, Anne D. Berhe, Luísa Mourão Dias Magalhães, Dhélio B. Pereira, Nichole D. Salinas +11 more

Protein-based antigen presentation platforms for nanoparticle vaccines

npj Vaccines(2021)10.1038/s41541-021-00330-7

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262 citations

Niraj H. Tolia, Brian Nguyen

Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA

Nature Microbiology(2021)10.1038/s41564-020-00858-9

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73 citations

Tengfei Lian, Rick Huang, Jonathan P. Renn, Jennifer D. Petersen, Joshua Zimmerberg +3 more

A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes

Nature Communications(2021)10.1038/s41467-021-21955-1

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67 citations

Wai Kwan Tang, Martin Burkhardt, Jacob D. Galson, Olga Muratova, Nichole D. Salinas +25 more

Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity

Communications Biology(2021)10.1038/s42003-021-02787-7

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26 citations

Justin Doritchamou, Bergeline C. Nguemwo Tentokam, Robert Morrison, Matthew V. Cowles, Martin Burkhardt +10 more

Structural vaccinology of malaria transmission-blocking vaccines

Expert Review of Vaccines(2021)10.1080/14760584.2021.1873135

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18 citations

Niraj H. Tolia, Palak Patel

Crystal structure of P. falciparum Cpn60 bound to ATP reveals an open dynamic conformation before substrate binding

Scientific Reports(2021)10.1038/s41598-021-85197-3

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5 citations

Rui Ma, Wai Kwan Tang, Dashuang Shi, Niraj H. Tolia, Brian Nguyen

Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.09.443238

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5 citations

Wai Kwan Tang, Brandi Butler, Tarik Ouahes, Sachy Orr-Gonzalez, Nichole D. Salinas +3 more

Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response

Science Advances(2022)10.1126/sciadv.abq8276

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57 citations

Wai Kwan Tang, Brandi Butler, Tarik Ouahes, Sachy Orr-Gonzalez, Nichole D. Salinas +3 more

Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion

Nature Communications(2022)10.1038/s41467-022-33336-3

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37 citations

Thayne H. Dickey, Christine S. Hopp, Ababacar Diouf, Wai Kwan Tang, Carole A. Long +4 more

Inhibition of a malaria host–pathogen interaction by a computationally designed inhibitor

Protein Science(2022)10.1002/pro.4507

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14 citations

Rachel Crow, Darya V. Urusova, Jason C. Klima, Niraj H. Tolia, Eva‐Maria Strauch +1 more

Structural analysis of Plasmodium falciparum ookinete surface antigen Pfs28 relevant for malaria vaccine design

Scientific Reports(2022)10.1038/s41598-022-24054-3

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10 citations

Wai Kwan Tang, Niraj H. Tolia, N. Shukla

Implications of conformational flexibility, lipid binding, and regulatory domains in cell-traversal protein CelTOS for apicomplexan migration

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102241

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8 citations

John R. Jimah, Santosh A. Misal, Nichole D. Salinas, Michal Fried, Paul H. Schlesinger +2 more

Protein-protein conjugation enhances the immunogenicity of SARS-CoV-2 receptor-binding domain (RBD) vaccines

iScience(2022)10.1016/j.isci.2022.104739

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7 citations

Christopher G. Rowe, Beth B. Chen, Thayne H. Dickey, Jonathan P. Renn, Lynn Lambert +5 more

Inhibition of a critical malaria host-pathogen interaction by a computationally designed inhibitor targeting Plasmodium vivax DBP

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.05.479252

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0 citations

Rachel Crow, Darya V. Urusova, Jason C. Klima, Niraj H. Tolia, Eva‐Maria Strauch +1 more

Conformational flexibility, lipid binding, and regulatory domains in CelTOS

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.31.486524

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0 citations

John R. Jimah, Francis B. Ntumngia, Santosh A. Misal, Samantha J. Barnes, Michal Fried +4 more

A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine

Immunity(2023)10.1016/j.immuni.2023.01.012

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37 citations

Camila H. Coelho, Kazutoyo Miura, Bergeline C. Nguemwo Tentokam, Nichole D. Salinas, David L. Narum +6 more

Structure-based design of a strain transcending AMA1-RON2L malaria vaccine

Nature Communications(2023)10.1038/s41467-023-40878-7

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26 citations

Thayne H. Dickey, Ababacar Diouf, Nichole D. Salinas, Holly McAleese, Tarik Ouahes +5 more

Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine

npj Vaccines(2023)10.1038/s41541-023-00619-9

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21 citations

Richi Gupta, Holly McAleese, Tarik Ouahes, Sachy Orr-Gonzalez, Rui Ma +7 more

Duffy antigen is expressed during erythropoiesis in Duffy-negative individuals

Cell Host & Microbe(2023)10.1016/j.chom.2023.10.019

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20 citations

Sébastien Dechavanne, Jürgen Bosch, Sylvain Métral, Karli R. Redinger, Quentin D. Watson +17 more

Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c01629

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14 citations

Caitlin M. DeAngelo, Kevin S. Blake, Hirdesh Kumar, Kendrick K. Lam, Katherine V. Jones +4 more

Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases

Communications Biology(2023)10.1038/s42003-023-04792-4

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14 citations

Emily E. Williford, Kevin S. Blake, Brett Virgin-Downey, Gautam Dantas, Timothy A. Wencewicz +2 more

A potent and durable malaria transmission-blocking vaccine designed from a single-component 60-copy Pfs230D1 nanoparticle

npj Vaccines(2023)10.1038/s41541-023-00709-8

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14 citations

Rui Ma, Thayne H. Dickey, Holly McAleese, Tarik Ouahes, Carole A. Long +4 more

Plasmodium falciparum exploits CD44 as a coreceptor for erythrocyte invasion

Blood(2023)10.1182/blood.2023020831

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13 citations

Chi Yong Kim, Carrie Lin, Angel K. Kongsomboonvech, Marilou Tétard, Nana Ansuah Peterson +4 more

Designing an effective malaria vaccine targeting Plasmodium vivax Duffy-binding protein

Trends in Parasitology(2023)10.1016/j.pt.2023.06.011

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12 citations

Niraj H. Tolia, Thayne H. Dickey

Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines

Cell Reports(2023)10.1016/j.celrep.2023.112266

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17 citations

Rui Ma, Sachy Orr-Gonzalez, Tarik Ouahes, Palak Patel, Holly McAleese +10 more

A human antibody epitope map of the malaria vaccine antigen Pfs25

npj Vaccines(2023)10.1038/s41541-023-00712-z

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7 citations

Wai Kwan Tang, Camila H. Coelho, Carole A. Long, Sara A. Healy, Issaka Sagara +4 more

Naturally acquired antibodies to gametocyte antigens are associated with reduced transmission of Plasmodium vivax gametocytes to Anopheles arabiensis mosquitoes

Frontiers in Cellular and Infection Microbiology(2023)10.3389/fcimb.2022.1106369

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6 citations

Wakweya Chali, Elifaged Hailemeskel, Jordache Ramjith, Abrham Gashaw, Temesgen Ashine +20 more

Plasmodium falciparum exploits CD44 as a co-receptor for erythrocyte invasion

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.12.536503

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0 citations

Chi Yong Kim, Carrie Lin, Angel K. Kongsomboonvech, Marilou Tétard, Nichole D. Salinas +3 more

Host receptor binding induces conformational changes in a PfEMP1 protein

Structure(2023)10.1016/j.str.2023.08.021

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0 citations

Niraj H. Tolia, Rui Ma

A Self-Assembling Pfs230D1-Ferritin Nanoparticle Vaccine Has Potent and Durable Malaria Transmission-Reducing Activity

Vaccines(2024)10.3390/vaccines12050546

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9 citations

Rui Ma, Holly McAleese, Tarik Ouahes, Carole A. Long, Kazutoyo Miura +3 more

Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria

Nature Communications(2024)10.1038/s41467-024-51701-2

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8 citations

Nichole D. Salinas, Surendra Kumar Kolli, Shulin Xu, Darya V. Urusova, Hirdesh Kumar +7 more

Structure-guided design of VAR2CSA-based immunogens and a cocktail strategy for a placental malaria vaccine

PLoS Pathogens(2024)10.1371/journal.ppat.1011879

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7 citations

Nichole D. Salinas, Sachy Orr-Gonzalez, Brandi Richardson, Tarik Ouahes, Holly Torano +12 more

Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes

Communications Biology(2024)10.1038/s42003-024-06023-w

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7 citations

Hirdesh Kumar, A. Loganathan, Emily E. Williford, Luke Diorio‐Toth, Yao-Peng Xue +8 more

Naturally acquired antibodies against Plasmodium vivax pre-erythrocytic stage vaccine antigens inhibit sporozoite invasion of human hepatocytes in vitro

Scientific Reports(2024)10.1038/s41598-024-51820-2

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6 citations

Surendra Kumar Kolli, Pradeep Annamalai Subramani, Samantha J. Barnes, Justin Nicholas, Madison M. Ogbondah +7 more

Structure‐based design of a Plasmodium vivax Duffy‐binding protein immunogen focuses the antibody response to functional epitopes

Protein Science(2024)10.1002/pro.5095

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1 citations

Holly McAleese, Nichole D. Salinas, Lynn Lambert, Niraj H. Tolia, Thayne H. Dickey

RH5 antigenic landscape shapes vaccine and antibody development

Trends in Pharmacological Sciences(2024)10.1016/j.tips.2024.10.008

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1 citations

Niraj H. Tolia, Palak Patel

A targetable receptor-binding site on PfCyRPA to aid in the fight against malaria

Trends in Parasitology(2024)10.1016/j.pt.2024.04.001

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0 citations

Niraj H. Tolia, Thayne H. Dickey

RBD design increases the functional antibody titers elicited by SARS-CoV-2 spike vaccination

Antiviral Research(2024)10.1016/j.antiviral.2024.105937

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0 citations

Nichole D. Salinas, Palak Patel, Sachy Orr-Gonzalez, Tarik Ouahes, Holly McAleese +9 more

The tetracycline resistome is shaped by selection for specific resistance mechanisms by each antibiotic generation

Nature Communications(2025)10.1038/s41467-025-56425-5

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56 citations

Yao-Peng Xue, Vincent J. Gillespie, Skye R. S. Fishbein, Niraj H. Tolia, Timothy A. Wencewicz +2 more

A combined designed CSP and Pfs48/45 infection and transmission blocking vaccine for malaria

npj Vaccines(2025)10.1038/s41541-025-01262-2

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1 citations

Thayne H. Dickey, Nichole D. Salinas, Palak Patel, Rui Ma, Dashuang Shi +8 more

C10-Benzoate Esters of Anhydrotetracycline Inhibit Tetracycline Destructases and Recover Tetracycline Antibacterial Activity

ACS Infectious Diseases(2025)10.1021/acsinfecdis.4c00912

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3 citations

Yao-Peng Xue, Wai Kwan Tang, Ruihao Li, Katherine V. Jones, Kevin S. Blake +7 more

A strain-transcending anti-AMA1 human monoclonal antibody neutralizes malaria parasites independent of direct RON2L receptor blockade

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.101985

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3 citations

Ababacar Diouf, Thayne H. Dickey, Wai Kwan Tang, Christine S. Hopp, Boubacar Traoré +5 more

CD44 cross-linking promotes Plasmodium falciparum invasion

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.30.667750

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0 citations

S.W. Scally, Yann Le Guen, Praveesh Valissery, Nichole D. Salinas, Alan F. Cowman +3 more

Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance

Communications Biology(2020)10.1038/s42003-020-0966-5

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199 citations

Jana L. Markley, Hirdesh Kumar, Bin Wang, Luting Fang, Sidra Irum +8 more

Plasmodium falciparum exploits NUAK1 to establish infection in human erythrocytes

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.30.685469

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0 citations

Chi Yong Kim, Kyle McLelland, Mario Gonzalez Ramirez, Bàrbara Baró, Nichole D. Salinas +6 more

A high affinity human monoclonal antibody against Pfs230 binds multiple parasite stages and blocks oocyst formation in mosquitoes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.25.313478

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3 citations

Wai Kwan Tang, Martin Burkhardt, Jacob D. Galson, Olga Muratova, Nichole D. Salinas +24 more