Ake T. Lu

Also affiliated with Altos Labs

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 33 papers. Top paper: “Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging”.

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

Genome biology(2021)10.1186/s13059-021-02398-9

N/A

5.8DataRank · unranked

307 citations

Josine L. Min, Rebecca Richmond, Ake T. Lu, Maria Sobczyk, Gail Davies +95 more

Clonal hematopoiesis associated with epigenetic aging and clinical outcomes

Aging Cell(2021)10.1111/acel.13366

N/A

3.3DataRank · unranked

134 citations

Ake T. Lu, Alexander G. Bick, Pradeep Natarajan, Joshua Weinstock, Mindy D Szeto +29 more

DNA methylation GrimAge version 2

Aging(2022)10.18632/aging.204434

N/A

0.855DataRank · unranked

298 citations

Alexandra M. Binder, Joshua Zhang, Qi Yan, Alex P. Reiner, Simon R. Cox +16 more

A mammalian methylation array for profiling methylation levels at conserved sequences

Nature Communications(2022)10.1038/s41467-022-28355-z

N/A

0.809DataRank · unranked

219 citations

Amin Haghani, Michael J. Thompson, Matteo Pellegrini, Soo Bin Kwon, Ha Vu +13 more

DNA methylation networks underlying mammalian traits

Science(2023)10.1126/science.abq5693

N/A

0.739DataRank · unranked

137 citations

Caesar Z. Li, Todd R. Robeck, Joshua Zhang, Ake T. Lu, Julia Ablaeva +93 more

Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons

Science(2021)10.1126/science.abb9032

N/A

0.721DataRank · unranked

121 citations

Patrick Reed, Johannes C. M. Schlachetzki, I Niţulescu, Grace Chou, Enoch C. Tsui +17 more

DNAmFitAge: biological age indicator incorporating physical fitness

Aging(2023)10.18632/aging.204538

N/A

0.692DataRank · unranked

100 citations

Zsolt Radak, Ferenc Torma, Matyas Jokai, Ake T. Lu, Daniel W. Belsky +15 more

Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals

Aging(2020)10.18632/aging.103408

N/A

0.574DataRank · unranked

45 citations

Riccardo E. Marioni, Cavin Ward‐Caviness, Rahul Gondalia, Weihua Guan, Brian Chen +44 more

Incorporation of a nucleoside analog maps genome repair sites in post-mitotic human neurons

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.25.008490

N/A

0.396DataRank · unranked

13 citations

Patrick Reed, Johannes C. M. Schlachetzki, Grace Chou, Sahaana Chandran, Ake T. Lu +14 more

Association of 4 epigenetic clocks with measures of functional health, cognition, and all-cause mortality in The Irish Longitudinal Study on Ageing (TILDA)

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.27.063164

N/A

0.373DataRank · unranked

11 citations

Giovanni Fiorito, Belinda Hernández, Silvia Polidoro, Aisling O’Halloran, Ann Hever +6 more

Effects of highly active antiretroviral therapy initiation on epigenomic DNA methylation in persons living with HIV

Frontiers in Bioinformatics(2024)10.3389/fbinf.2024.1357889

N/A

0.292DataRank · unranked

6 citations

Mary E. Sehl, Roger Shih, Elizabeth C. Breen, Fengxue Li, Ake T. Lu +9 more

Early life adversity predicts an accelerated cellular aging phenotype through early timing of puberty

Psychological Medicine(2023)10.1017/s0033291723001629

N/A

0DataRank · unranked

27 citations

Torsten B. Neilands, Barbara Laraia, Joshua Zhang, Ake T. Lu, Jue Lin +3 more

Pan-primate studies of age and sex

GeroScience(2023)10.1007/s11357-023-00878-3

N/A

0DataRank · unranked

24 citations

Amin Haghani, Joseph A. Zoller, Ake T. Lu, Jason Ernst, Matteo Pellegrini +14 more

Bloom syndrome patients and mice display accelerated epigenetic aging

Aging Cell(2023)10.1111/acel.13964

N/A

0DataRank · unranked

14 citations

Joshua Zhang, Maeve Flanagan, Julián A. Martínez-Agosto, Christopher Cunniff, Nicole Kucine +6 more

Associations of Epigenetic Age Estimators With Cognitive Function Trajectories in the Women's Health Initiative Memory Study

Neurology(2024)10.1212/wnl.0000000000209534

N/A

0DataRank · unranked

16 citations

Linda K. McEvoy, Mark A. Espeland, Eric A. Whitsel, Ake T. Lu, Steve Horvath +4 more

Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations

Epigenetics(2024)10.1080/15592294.2024.2333668

N/A

0DataRank · unranked

9 citations

Ulrike Peters, Yao Hu, Farah Ammous, Christy L. Avery, Emelia J. Benjamin +35 more

Relationships of depression and antidepressant use with epigenetic age acceleration and all-cause mortality among postmenopausal women

Aging(2024)10.18632/aging.205868

N/A

0DataRank · unranked

6 citations

Hind A. Beydoun, Jason Ashe, Michael F. Georgescu, Steve Horvath, Ake T. Lu +8 more

Longitudinal changes in epigenetic clocks predict survival in the InCHIANTI cohort

medRxiv(2024)10.1101/2024.09.13.24313620

N/A

0DataRank · unranked

6 citations

Ann Zenobia Moore, Toshiko Tanaka, Daniel W. Belsky, Ake T. Lu, Steve Horvath +3 more

Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations

UNC Libraries(2024)10.17615/b6xd-h115

N/A

0DataRank · unranked

0 citations

Eimear E. Kenny, Chunyu Liu, Christy L. Avery, On Behalf of the PAGE Study, Nona Sotoodehnia +35 more

Epigenetic clocks of biological aging and risk of incident mild cognitive impairment and dementia: the Women’s Health Initiative Memory Study

medRxiv(2025)10.1101/2025.09.29.25336927

N/A

0DataRank · unranked

1 citations

Ake T. Lu, Steve Horvath, Mark A. Espeland, Stephen R. Rapp, Adam X. Maihofer +7 more

Relationships of depression and antidepressant use with epigenetic age acceleration and all-cause mortality among postmenopausal women

UNC Libraries(2025)10.17615/en40-wv64

N/A

0DataRank · unranked

0 citations

Ramon Casanova, May A. Beydoun, Jason Ashe, Ake T. Lu, Aladdin H. Shadyab +8 more

Epigenetic clocks and longitudinal plasma biomarkers of Alzheimer’s disease

medRxiv(2025)10.1101/2025.08.12.25333453

N/A

0DataRank · unranked

0 citations

Linda K. McEvoy, Steve Nguyen, Mark A. Espeland, Stephen R. Rapp, Steve Horvath +13 more

Significant variation in the performance of DNA methylation predictors across data preprocessing and normalization strategies

Genome biology(2022)10.1186/s13059-022-02793-w

N/A

0DataRank · unranked

47 citations

Ake T. Lu, Steve Horvath, Roel A. Ophoff, Anil P. S. Ori

Pan-primate DNA methylation clocks

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.29.402891

N/A

0DataRank · unranked

14 citations

Amin Haghani, Joseph A. Zoller, Ake T. Lu, Jason Ernst, Matteo Pellegrini +14 more

GWAS of epigenetic aging rates in blood reveals a critical role for TERT

UNC Libraries(2020)10.17615/p8eg-8t23

N/A

0DataRank · unranked

0 citations

Jordana T. Bell, İdil Yet, Morgan E. Levine, Nicholas J. Wareham, Themistocles L. Assimes +34 more

Epigenetic Age and the Risk of Incident Atrial Fibrillation

Circulation(2021)10.1161/circulationaha.121.056456

N/A

0DataRank · unranked

118 citations

Eric Vittinghoff, Ake T. Lu, Álvaro Alonso, Biqi Wang, Colleen M. Sitlani +23 more

DNA methylation age analysis of rapamycin in common marmosets

GeroScience(2021)10.1007/s11357-021-00438-7

N/A

0DataRank · unranked

43 citations

Joseph A. Zoller, Amin Haghani, Ake T. Lu, Ken Raj, Anna J. Jasinska +3 more

Epigenetic clock and methylation studies in dogs

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.30.437604

N/A

0DataRank · unranked

8 citations

Ake T. Lu, Amin Haghani, Joseph A. Zoller, Robert T. Brooke, Ken Raj +4 more

A systematic evaluation of 41 DNA methylation predictors across 101 data preprocessing and normalization strategies highlights considerable variation in algorithm performance

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.29.462387

N/A

0DataRank · unranked

4 citations

Ake T. Lu, Steve Horvath, Roel A. Ophoff, Anil P. S. Ori

Epigenetic aging of the demographically non-aging naked mole-rat

Nature Communications(2022)10.1038/s41467-022-27959-9

N/A

0DataRank · unranked

61 citations

Margarita Meer, Julia Ablaeva, Vince G. Amoroso, Sang‐Goo Lee, Bohan Zhang +11 more

GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality

The Journals of Gerontology Series A(2020)10.1093/gerona/glaa286

N/A

0DataRank · unranked

483 citations

Giovanni Fiorito, Belinda Hernández, Silvia Polidoro, Aisling O’Halloran, Ann Hever +6 more

Universal DNA methylation age across mammalian tissues

Nature Aging(2023)10.1038/s43587-023-00462-6

N/A

0DataRank · unranked

396 citations

Zhe Fei, Amin Haghani, Todd R. Robeck, Joseph A. Zoller, Caesar Z. Li +95 more

Multi-omic rejuvenation and lifespan extension on exposure to youthful circulation

Nature Aging(2023)10.1038/s43587-023-00451-9

N/A

0DataRank · unranked

130 citations

David E. Lee, Alexandre Trapp, Alexander Tyshkovskiy, Ake T. Lu, Akshay Bareja +9 more