Timothy R. Billiar

Immunology and MicrobiologyMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 52 papers. Top paper: “Prehospital plasma is associated with distinct biomarker expression following injury”.

Prehospital plasma is associated with distinct biomarker expression following injury

JCI Insight(2020)10.1172/jci.insight.135350

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1.9DataRank · unranked

102 citations

Joshua B. Brown, Francis X. Guyette, Yoram Vodovotz, Pär I. Johansson, Jakob Stensballe +13 more

Decoding the multiple functions of ZBP1 in the mechanism of sepsis-induced acute lung injury

Communications Biology(2024)10.1038/s42003-024-07072-x

N/A

0.681DataRank · unranked

26 citations

Yu Fu, Qingde Wang, Patricia Loughran, Yuehua Li, Timothy R. Billiar +4 more

Lipidomic Signatures Align with Inflammatory Patterns and Outcomes in Critical Illness

Research Square(2021)10.21203/rs.3.rs-106579/v1

N/A

0.416DataRank · unranked

15 citations

Anthony R. Cyr, Danielle S. Gruen, Tyler Lovelace, Panayiotis V. Benos, Tianmeng Chen +17 more

Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis

The FASEB Journal(2020)10.1096/fj.202002150r

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0DataRank · unranked

18 citations

Dijoia B. Darden, Zhongkai Wang, Dina C. Nacionales, Maria-Cecilia Lopez, Russell B. Hawkins +19 more

Unsupervised Clustering Analysis Based on MODS Severity Identifies Four Distinct Organ Dysfunction Patterns in Severely Injured Blunt Trauma Patients

Frontiers in Medicine(2020)10.3389/fmed.2020.00046

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0DataRank · unranked

20 citations

Rami A. Namas, Yoram Vodovotz, Andrew B. Peitzman, Richard L. Simmons, Hong Yuan +3 more

A road map from single-cell transcriptome to patient classification for the immune response to trauma

JCI Insight(2020)10.1172/jci.insight.145108

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0DataRank · unranked

47 citations

Matthew J. Delano, Kong Chen, Jason L. Sperry, Rami A. Namas, Ashley J. Lamparello +11 more

Hepatocyte high-mobility group box 1 protects against steatosis and cellular stress during high fat diet feeding

Research Square(2020)10.21203/rs.3.rs-30696/v3

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0DataRank · unranked

0 citations

Jungke Long, Wenbo Li, Chenxuan Yang, Patricia Loughran, Robert M. O’Doherty +4 more

Platelet TLR4-ERK5 Axis Facilitates NET-Mediated Capturing of Circulating Tumor Cells and Distant Metastasis after Surgical Stress

Cancer Research(2021)10.1158/0008-5472.can-20-3222

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0DataRank · unranked

160 citations

Jiayi He, Hongji Zhang, Yujia Xia, Zhiwei Hu, Patricia Loughran +4 more

Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses

Cell Reports Medicine(2021)10.1016/j.xcrm.2021.100478

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0DataRank · unranked

80 citations

Yoram Vodovotz, Sultan Abdelhamid, Francis X. Guyette, Michael B Yaffe, Danielle S. Gruen +23 more

Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain

Journal of Neuroinflammation(2021)10.1186/s12974-021-02217-9

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0DataRank · unranked

52 citations

Clayton A. Wiley, Richard A. Steinman, Sheng Yi, Beihong Ji, Junmei Wang +6 more

The HIV protease inhibitor Saquinavir attenuates sepsis-induced acute lung injury and promotes M2 macrophage polarization via targeting matrix metalloproteinase-9

Cell Death and Disease(2021)10.1038/s41419-020-03320-0

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0DataRank · unranked

44 citations

Zhuang Yu, Zhixia Chen, Renlingzi Zhang, Xibing Ding, Xiaohu Yang +7 more

Hepatocytes Are Resistant to Cell Death From Canonical and Non-Canonical Inflammasome-Activated Pyroptosis

Cellular and Molecular Gastroenterology and Hepatology(2021)10.1016/j.jcmgh.2021.11.009

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0DataRank · unranked

37 citations

Jie Zhong, Hong Liao, Patricia Loughran, Joud Mulla, Guang Fu +6 more

Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway

Molecular Medicine(2021)10.1186/s10020-021-00280-9

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0DataRank · unranked

31 citations

Guang Fu, Wenbo Li, Ping Sun, Patricia Loughran, Meihong Deng +3 more

Analysis of the Plasma Metabolome after Trauma, Novel Circulating Sphingolipid Signatures, and In-Hospital Outcomes

Journal of the American College of Surgeons(2021)10.1016/j.jamcollsurg.2020.12.022

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0DataRank · unranked

24 citations

Yanjun Zhong, Steven E. Reís, Rami A. Namas, Andrew A. Amoscato, Brian S. Zuckerbraun +5 more

Computational Derivation of Core, Dynamic Human Blunt Trauma Inflammatory Endotypes

Frontiers in Immunology(2021)10.3389/fimmu.2020.589304

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0DataRank · unranked

21 citations

Haley Lindberg, Maria Cohen, Rami A. Namas, Qi Mi, Jinling Yin +7 more

Spatiotemporally specific roles of TLR4, TNF, and IL-17A in murine endotoxin-induced inflammation inferred from analysis of dynamic networks

Molecular Medicine(2021)10.1186/s10020-021-00333-z

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0DataRank · unranked

21 citations

Sangeeta S. Chavan, Theodoros P. Zanos, Richard L. Simmons, Timothy R. Billiar, Yoram Vodovotz +1 more

ADAR1 RNA editing regulates endothelial cell functions via the MDA-5 RNA sensing signaling pathway

Life Science Alliance(2021)10.26508/lsa.202101191

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0DataRank · unranked

16 citations

Silvia Liu, Rose Yan, Vy Nguyen, Mazen Zenati, Timothy R. Billiar +2 more

Analysis of glutathione mediated S-(de)nitrosylation in complex biological matrices by immuno-spin trapping and identification of two novel substrates

Nitric Oxide(2021)10.1016/j.niox.2021.10.008

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0DataRank · unranked

13 citations

Detcho A. Stoyanovsky, Timothy R. Billiar, Arne Holmgren, Rajib Sengupta, Esha Sircar

A putative “chemokine switch” that regulates systemic acute inflammation in humans

Scientific Reports(2021)10.1038/s41598-021-88936-8

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0DataRank · unranked

20 citations

Rami A. Namas, Khalid Almahmoud, Akram Zaaqoq, Othman Abdul Malak, Derek Barclay +8 more

The Whole is Greater Than the Sum of its Parts: GCS Versus GCS-Motor for Triage in Geriatric Trauma

Journal of Surgical Research(2021)10.1016/j.jss.2020.12.051

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0DataRank · unranked

19 citations

Heather Phelos, Andrew B. Peitzman, Timothy R. Billiar, Jason L. Sperry, Joshua B. Brown +1 more

Protective/reparative cytokines are suppressed at high injury severity in human trauma

Trauma Surgery & Acute Care Open(2021)10.1136/tsaco-2020-000619

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0DataRank · unranked

19 citations

Todd O. McKinley, Isabel M. Billiar, Mazen S. Zenati, Greg E. Gaski, Yoram Vodovotz +4 more

Targeting Nitric Oxide: Say NO to Metastasis

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-22-2791

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0DataRank · unranked

64 citations

Sharon A. Glynn, Timothy R. Billiar, David A. Wink, Jenny C. Chang, T. P. Reddy

Lipidomic signatures align with inflammatory patterns and outcomes in critical illness

Nature Communications(2022)10.1038/s41467-022-34420-4

N/A

0DataRank · unranked

55 citations

Anthony R. Cyr, Danielle S. Gruen, Tyler Lovelace, Panayiotis V. Benos, Jishnu Das +55 more

Multi-Omic Admission-Based Prognostic Biomarkers Identified by Machine Learning Algorithms Predict Patient Recovery and 30-Day Survival in Trauma Patients

Metabolites(2022)10.3390/metabo12090774

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0DataRank · unranked

19 citations

Jacob Scioscia, Yoram Vodovotz, Junru Wu, Anna Rosengart, Eunseo Sung +11 more

Intraperitoneal injection of class A TLR9 agonist enhances anti–PD-1 immunotherapy in colorectal peritoneal metastases

JCI Insight(2022)10.1172/jci.insight.160063

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0DataRank · unranked

10 citations

Hongji Zhang, Yiming Li, Preethi Jayakumar, Hong Liao, Hai Huang +3 more

GRK2 regulates group 2 innate lymphoid cell mobilization in sepsis

Molecular Medicine(2022)10.1186/s10020-022-00459-8

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0DataRank · unranked

8 citations

Weiwei Chen, Kai Zhang, Melanie J. Scott, Yuehua Li, Timothy R. Billiar +2 more

Plasma proteomics reveals early, broad release of chemokine, cytokine, TNF, and interferon mediators following trauma with delayed increases in a subset of chemokines and cytokines in patients that remain critically ill

Frontiers in Immunology(2022)10.3389/fimmu.2022.1038086

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0DataRank · unranked

17 citations

Isabel M. Billiar, Hamed Moheimani, Junru Wu, Rami A. Namas, Shimena Li +6 more

Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis

Immunity(2023)10.1016/j.immuni.2023.11.001

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0DataRank · unranked

44 citations

Chunhua Yu, Herbert J. Zeh, Haichao Wang, Guido Kroemer, Daniel J. Klionsky +4 more

ADAR1 Zα domain P195A mutation activates the MDA5-dependent RNA-sensing signaling pathway in brain without decreasing overall RNA editing

Cell Reports(2023)10.1016/j.celrep.2023.112733

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0DataRank · unranked

32 citations

Silvia Liu, Sheng Yi, Mazen Zenati, Timothy R. Billiar, Alan Herbert +2 more

Interferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcome

Cell Death and Disease(2023)10.1038/s41419-023-05834-9

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0DataRank · unranked

17 citations

Lisa A. Ridnour, Adelaide L. Wink, Ana L. González, Elise L. Femino, Helene Rittscher +20 more

Nitric oxide and thioredoxin modulate the activity of caspase 9 in HepG2 cells

Biochimica et Biophysica Acta (BBA) - General Subjects(2023)10.1016/j.bbagen.2023.130452

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0DataRank · unranked

8 citations

Ankita Choudhuri, Akansha Mishra, Camelia Bhattacharyya, Timothy R. Billiar, Detcho A. Stoyanovsky +2 more

A common single nucleotide polymorphism is associated with inflammation and critical illness outcomes

iScience(2023)10.1016/j.isci.2023.108333

N/A

0DataRank · unranked

4 citations

Rubén Zamora, Josiah E. Radder, Jinling Yin, Ashti M. Shah, Rami A. Namas +11 more

Transcriptomic and Proteomic Characterization of the Immune Response to Elective Spinal Reconstructive Surgery: Impact of Aging and Comparison with Traumatic Injury Response

Journal of the American College of Surgeons(2023)10.1097/xcs.0000000000000922

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0DataRank · unranked

4 citations

Mehves Ozel, Tianmeng Chen, Jennifer L. Darby, Xuejing Sun, Hamed Moheimani +7 more

An adaptive, negative feedback circuit in a biohybrid device reprograms dynamic networks of systemic inflammation in vivo

Frontiers in Systems Biology(2023)10.3389/fsysb.2022.926618

N/A

0DataRank · unranked

3 citations

Maxim Mikheev, Jinling Yin, Derek Barclay, Bahiyyah Jefferson, Qi Mi +5 more

A Prospective Cohort Protocol for the Remnant Investigation in Sepsis Study

Critical Care Explorations(2023)10.1097/cce.0000000000000974

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0DataRank · unranked

2 citations

Kelly Urbanek, Anna Nakayama, Jason Kennedy, Rachel E. Powell, Renã A. S. Robinson +14 more

Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER- breast cancer patients

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.21.572867

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0DataRank · unranked

2 citations

Robert Y.S. Cheng, William F. Heinz, Milind Pore, Ana L. González, Elise L. Femino +22 more

NOS2 and COX2 Provide Key Spatial Targets that Determine Outcome in ER-Breast Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.21.572859

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0DataRank · unranked

1 citations

William F. Heinz, Robert Y.S. Cheng, Adelaide L. Wink, Noémi Kedei, Milind Pore +21 more

Interferon-gamma is Quintessential for NOS2 and COX2 Expression in ER - Breast Tumors that Lead to Poor Outcome

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.06.535916

N/A

0DataRank · unranked

0 citations

Lisa A. Ridnour, Adelaide L. Wink, Ana L. González, Elise L. Femino, Helene Rittscher +20 more

IRG1/ACOD1 promotes neutrophil reverse migration and alleviates local inflammation

Journal of Leukocyte Biology(2024)10.1093/jleuko/qiae110

N/A

0DataRank · unranked

13 citations

Hanhui Zhong, Yuehua Li, Timothy R. Billiar, Mark A. Wilson, Melanie J. Scott +2 more

Mechanism matters: mortality and endothelial cell damage marker differences between blunt and penetrating traumatic injuries across three prehospital clinical trials

Scientific Reports(2024)10.1038/s41598-024-53398-1

N/A

0DataRank · unranked

17 citations

Danielle S. Gruen, Nidhi Iyanna, John M. Lorence, Joshua B. Brown, Francis X. Guyette +14 more

A unified model-based framework for doublet or multiplet detection in single-cell multiomics data

Nature Communications(2024)10.1038/s41467-024-49448-x

N/A

0DataRank · unranked

14 citations

Xinjun Wang, S. H. Feng, Zhongli Xu, Jing Liu, Elisa Heidrich-O’Hare +11 more

Activation of TLR9 signaling suppresses the immunomodulating functions of CD55lo fibroblastic reticular cells during bacterial peritonitis

Frontiers in Immunology(2024)10.3389/fimmu.2024.1337384

N/A

0DataRank · unranked

4 citations

Yiming Li, Xingping Huang, Preethi Jayakumar, Timothy R. Billiar, Meihong Deng +1 more

Value of animal sepsis research in navigating the translational labyrinth

Frontiers in Immunology(2025)10.3389/fimmu.2025.1593342

N/A

0DataRank · unranked

10 citations

Alfred Ayala, Monowar Aziz, Timothy R. Billiar, Clifford S. Deutschman, Samithamby Jeyaseelan +3 more

High-grade liver injury: outcomes with a trauma surgery–liver surgery collaborative approach

Trauma Surgery & Acute Care Open(2025)10.1136/tsaco-2024-001611

N/A

0DataRank · unranked

9 citations

Andrew–Paul Deeb, Evelyn I. Truong, David Newhouse, Sowmya Narayanan, Louis H. Alarcon +19 more

High-dimensional analysis of injured patients reveals distinct circulating proteomic profiles in plasma vs. whole blood resuscitation

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.102022

N/A

0DataRank · unranked

5 citations

Xuejing Sun, Mehves Ozel, Jennifer L. Darby, Erika P. Ong, Tunde Oyebamiji +16 more

Elevated tumor NOS2/COX2 promotes immunosuppressive phenotypes associated with poor survival in ER– breast cancer

JCI Insight(2025)10.1172/jci.insight.193091

N/A

0DataRank · unranked

5 citations

Robert Y.S. Cheng, William F. Heinz, Milind Pore, Ana L. González, Elise L. Femino +22 more

Single-cell transcriptomic analysis identified resistant MDSCs and a stress-tolerant gene co-expression network as common MDSC features across multiple disease settings

Frontiers in Immunology(2025)10.3389/fimmu.2025.1565211

N/A

0DataRank · unranked

1 citations

Julia Hughes, Alyssa D. Gregory, Julia L Conroy, Patricia Loughran, Jinming Song +3 more

Caspase-11 regulates systemic inflammation and cell death in a cell-specific manner after trauma with shock

Journal of Leukocyte Biology(2025)10.1093/jleuko/qiaf121

N/A

0DataRank · unranked

1 citations

Alyssa D. Gregory, Hong Liao, Bashar Al Matour, Yuzhen Li, Abiha Abdullah +3 more

TMEM173 Drives Lethal Coagulation in Sepsis

Cell Host & Microbe(2020)10.1016/j.chom.2020.02.004

N/A

0DataRank · unranked

198 citations

Ling Zeng, Min Xie, Jiao Liu, Bo Zhou, Runliu Wu +10 more

Aicardi-Goutières Syndrome Associated ADAR G1007R mutation dominantly induces neuroinflammation in mouse brain

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.21.649787

N/A

0DataRank · unranked

0 citations

Jiajun Liu, Chaowei Shang, Christopher J. Guerriero, Clayton A. Wiley, Richard A. Steinman +6 more

LPS Induces Active HMGB1 Release From Hepatocytes Into Exosomes Through the Coordinated Activities of TLR4 and Caspase-11/GSDMD Signaling

Frontiers in Immunology(2020)10.3389/fimmu.2020.00229

N/A

0DataRank · unranked

143 citations

Meihong Deng, Patricia Loughran, Muqing Yang, Minjie Lin, Chenxuan Yang +8 more

Hepatocyte high-mobility group box 1 protects against steatosis and cellular stress during high fat diet feeding

Molecular Medicine(2020)10.1186/s10020-020-00227-6

N/A

0DataRank · unranked

21 citations

Jungke Long, Wenbo Li, Chenxuan Yang, Patricia Loughran, Robert M. O’Doherty +4 more