Greg M. Delgoffe

Also affiliated with UPMC Hillman Cancer Center

MedicineImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 37 papers. Top paper: “LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity”.

LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity

Cell(2024)10.1016/j.cell.2024.07.016

N/A

0.828DataRank · unranked

249 citations

Samuel C. Butler, Jian Cui, Anthony R. Cillo, Carly Cardello, Chang Liu +15 more

Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-22-2661

N/A

0.542DataRank · unranked

36 citations

Ashley V. Menk, Dayana B. Rivadeneira, Ryan C. Augustin, Mingchu Xu, Jun Li +47 more

Thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination in genomic DNA, cell death, and interferon-α/β expression

Cell Reports(2022)10.1016/j.celrep.2022.111371

N/A

0.489DataRank · unranked

25 citations

Frank P. Vendetti, Andrew J. Cipriano, Pinakin Pandya, Joshua J. Deppas, Tatiana N. Moiseeva +12 more

Thymidine rescues ATR kinase inhibition induced deoxyuridine contamination in genomic DNA, cell death, and Type 1 interferon expression

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.24.481821

N/A

0.104DataRank · unranked

1 citations

Frank P. Vendetti, Andrew J. Cipriano, Pinakin Pandya, Joshua J. Deppas, Tatiana N. Moiseeva +12 more

CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours

Nature(2021)10.1038/s41586-021-03326-4

N/A

0DataRank · unranked

395 citations

Inna Serganova, Ivan Cohen, Masatomo Maeda, Masahiro Shindo, Yasin Şenbabaoğlu +19 more

Expression of Tim-3 drives phenotypic and functional changes in Treg cells in secondary lymphoid organs and the tumor microenvironment

Cell Reports(2021)10.1016/j.celrep.2021.109699

N/A

0DataRank · unranked

96 citations

Hector Nieves-Rosado, Aditi Kulkarni, Benjamin Murter, Kyle McGrath, Uma Chandran +7 more

Metabolic regulation of T cells in the tumor microenvironment by nutrient availability and diet

Seminars in Immunology(2021)10.1016/j.smim.2021.101485

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0DataRank · unranked

51 citations

Ronal M. Peralta, Natalia Avina-Ochoa, Greg M. Delgoffe, Susan M. Kaech, Steven Zhao

Altered costimulatory signals and hypoxia support chromatin landscapes limiting the functional potential of exhausted T cells in cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.11.451947

N/A

0DataRank · unranked

7 citations

Natalie Rittenhouse, Nicole E. Scharping, Paolo Vignali, Andrew Frisch, Ronal M. Peralta +3 more

Evaluation of radiomics as a predictor of tumor hypoxia and response to anti-PD-1 mab treatment (IO) in recurrent/metastatic HNSCC patients (R/M).

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.6045

N/A

0DataRank · unranked

1 citations

Şerafettin Zenkin, Murat Ak, Priyadarshini Mamindla, Vishal Peddagangireddy, Ashley V. Menk +7 more

Excess dietary sugar impairs colonic epithelial regeneration in response to damage

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.18.456840

N/A

0DataRank · unranked

1 citations

Junyi Ji, Kadir Ozler, Onur Eskiocak, Brian Yueh, Ashley V. Menk +12 more

Tumor hypoxia drives suppressor function in exhausted T cells limiting antitumor immunity

Research Square(2021)10.21203/rs.3.rs-924657/v1

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0DataRank · unranked

1 citations

Paolo Vignali, Kristin DePeaux, McLane J. Watson, Konstantinos Lontos, Nicole McGaa +3 more

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

Nature Immunology(2022)10.1038/s41590-022-01379-9

N/A

0DataRank · unranked

256 citations

Kristin DePeaux, McLane J. Watson, Chenxian Ye, B. Rhodes Ford, Konstantinos Lontos +8 more

Fighting in a wasteland: deleterious metabolites and antitumor immunity

Journal of Clinical Investigation(2022)10.1172/jci148549

N/A

0DataRank · unranked

69 citations

Greg M. Delgoffe, McLane J. Watson

Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity

Cell Host & Microbe(2022)10.1016/j.chom.2022.02.017

N/A

0DataRank · unranked

67 citations

Chetan V. Jawale, Chunsheng Zhou, Lin Li, Giraldina J Trevejo-Nunez, Syed A. Rahman +8 more

Fully murine CD105-targeted CAR-T cells provide an immunocompetent model for CAR-T cell biology

OncoImmunology(2022)10.1080/2162402x.2022.2131229

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0DataRank · unranked

14 citations

Yiyang Wang, Mason Colbert, Alok Kumar, Supriya Joshi, Mary Philbin +6 more

Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors

Journal for ImmunoTherapy of Cancer(2023)10.1136/jitc-2022-006522

N/A

0DataRank · unranked

100 citations

Yiyang Wang, Supriya Joshi, Andrew Frisch, McLane J. Watson, Alok Kumar +8 more

An oncolytic virus–delivered TGFβ inhibitor overcomes the immunosuppressive tumor microenvironment

The Journal of Experimental Medicine(2023)10.1084/jem.20230053

N/A

0DataRank · unranked

45 citations

Dayana B. Rivadeneira, Konstantinos Lontos, Victoria Dean, William G. Gunn, McLane J. Watson +8 more

Integrating innate and adaptive immunity in oncolytic virus therapy

Trends in cancer(2023)10.1016/j.trecan.2023.09.012

N/A

0DataRank · unranked

38 citations

Greg M. Delgoffe, Kristin DePeaux

The schedule of ATR inhibitor AZD6738 can potentiate or abolish antitumor immune responses to radiotherapy

JCI Insight(2023)10.1172/jci.insight.165615

N/A

0DataRank · unranked

36 citations

Pinakin Pandya, David A. Clump, Sandra Schamus-Haynes, Meysam Tavakoli, Maria diMayorca +6 more

Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage

Cellular and Molecular Gastroenterology and Hepatology(2023)10.1016/j.jcmgh.2023.05.001

N/A

0DataRank · unranked

25 citations

Junyi Ji, Kadir Ozler, Heather Mentrup, Onur Eskiocak, Brian Yueh +15 more

Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection

PLoS Pathogens(2023)10.1371/journal.ppat.1011719

N/A

0DataRank · unranked

13 citations

Brian R. Kocak, Matthew R. Hendricks, Jeffrey A. Melvin, Katrina B. Mar, Jessica L. Kosanovich +7 more

Antiviral epithelial-macrophage crosstalk permits secondary bacterial infections

mBio(2023)10.1128/mbio.00863-23

N/A

0DataRank · unranked

10 citations

Tristan L. A. White, E. Walsh, Richard Cattley, Rachel Cumberland, William F. Hawse +4 more

Dysfunction of exhausted T cells is enforced by MCT11-mediated lactate metabolism

Nature Immunology(2024)10.1038/s41590-024-01999-3

N/A

0DataRank · unranked

145 citations

Bingxian Xie, Konstantinos Lontos, Hector Nieves-Rosado, Kellie Spahr, Supriya Joshi +12 more

Tim-3 Is Required for Regulatory T Cell–Mediated Promotion of T Cell Exhaustion and Viral Persistence during Chronic Lymphocytic Choriomeningitis Virus Infection

The Journal of Immunology(2024)10.4049/jimmunol.2400119

N/A

0DataRank · unranked

8 citations

Hridesh Banerjee, Angela Gocher-Demske, Priyanka Manandhar, Isha Mehta, Ogechukwu Ezenwa +7 more

Treatment with oncolytic vaccinia virus infects tumor-infiltrating regulatory and exhausted T cells

Journal for ImmunoTherapy of Cancer(2024)10.1136/jitc-2024-009062

N/A

0DataRank · unranked

6 citations

William Gunn, Dayana B. Rivadeneira, Greg M. Delgoffe, Kristin DePeaux

Evaluation of radiomics as a predictor of efficacy and the tumor immune microenvironment in anti‐PD‐1 mAb treated recurrent/metastatic squamous cell carcinoma of the head and neck patients

Head & Neck(2024)10.1002/hed.27878

N/A

0DataRank · unranked

5 citations

Şerafettin Zenkin, Murat Ak, Priyadarshini Mamindla, Vishal Peddagangireddy, Ronan W. Hsieh +8 more

An IRF2-Expressing Oncolytic Virus Changes the Susceptibility of Tumor Cells to Antitumor T Cells and Promotes Tumor Clearance

Cancer Immunology Research(2024)10.1158/2326-6066.cir-23-0573

N/A

0DataRank · unranked

6 citations

Rashmi Srivastava, Greg M. Delgoffe, Stephen H. Thorne, Saumendra N. Sarkar, Lulu Shao

Engineered protein destabilization reverses intrinsic immune evasion for candidate vaccine pan-strain KSHV and SARS-CoV-2 antigens

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.22.619692

N/A

0DataRank · unranked

2 citations

Bingxian Xie, Masahiro Shuda, Greg M. Delgoffe, Yuan Chang, Patrick S. Moore +1 more

Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy

Cell Metabolism(2025)10.1016/j.cmet.2024.12.007

N/A

0DataRank · unranked

36 citations

Yiyang Wang, Bingxian Xie, Aaron Yang, B. Rhodes Ford, Supriya Joshi +14 more

Oxidative-stress-induced telomere instability drives T cell dysfunction in cancer

Immunity(2025)10.1016/j.immuni.2025.08.008

N/A

0DataRank · unranked

22 citations

Sanjana Thosar, Kevin Quann, William Gunn, Victoria Dean, Bingxian Xie +9 more

Sucralose Consumption Ablates Cancer Immunotherapy Response through Microbiome Disruption

Cancer Discovery(2025)10.1158/2159-8290.cd-25-0247

N/A

0DataRank · unranked

13 citations

Madison Nguyen, Drew N. Wilfahrt, Zakaria Larbi Dahmani, Ansen B.P. Burr, Bingxian Xie +15 more

Reprogramming CD8+ T-cell Branched N- Glycosylation Limits Exhaustion, Enhancing Cytotoxicity and Tumor Killing

Cancer Immunology Research(2025)10.1158/2326-6066.cir-25-0313

N/A

0DataRank · unranked

6 citations

Bingxian Xie, William G. Gunn, Ronal M. Peralta, Carolina S. Dantas, Henrique Fernandes-Mendes +13 more

Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis

Nature Immunology(2020)10.1038/s41590-020-0598-4

N/A

0DataRank · unranked

272 citations

Steven J. Mullett, Rebecca A. Elsner, Ashley V. Menk, Nikita Trivedi, Wei Luo +12 more

Zinc availability in the tumor microenvironment dictates anti-PD1 response in CDKN2A Low tumors via increased macrophage phagocytosis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.08.637227

N/A

0DataRank · unranked

3 citations

Aidan R. Cole, Jeff Danielson, Jimmy P. Xu, Drew E. Hurd, Akash Kishore +33 more

NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer

JCI Insight(2020)10.1172/jci.insight.131486

N/A

0DataRank · unranked

52 citations

M. R. S. Iyengar, Santiago Panesso-Gómez, Patrick O’Hayer, Daniel Chan, Greg M. Delgoffe +5 more

The impact of tumor hypoxia on the clinical efficacy of anti-PD-1 mAb treatment in recurrent/metastatic HNSCC patients (R/M).

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.6546

N/A

0DataRank · unranked

10 citations

Maria A. Velez, Ashley V. Menk, Angen Liu, Heath D. Skinner, Umamaheswar Duvvuri +7 more

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

Nature(2021)10.1038/s41586-020-03045-2

N/A

0DataRank · unranked

1257 citations

Paolo Vignali, Steven J. Mullett, Abigail E. Overacre-Delgoffe, Ronal M. Peralta, Stephanie Grebinoski +12 more