Jeffrey M. McKenna

Also affiliated with Berkeley College, Novartis (China), Novartis (Ireland)

Biochemistry, Genetics and Molecular BiologyChemistryMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 24 papers. Top paper: “Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC”.

Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC

Cell chemical biology(2020)10.1016/j.chembiol.2020.09.001

N/A

0DataRank · unranked

161 citations

Alexander G. Cioffi, Felix C. Majewski, Jennifer Co, Nathaniel J. Henning, Michael D. Jones +6 more

Bardoxolone conjugation enables targeted protein degradation of BRD4

Scientific Reports(2020)10.1038/s41598-020-72491-9

N/A

0DataRank · unranked

140 citations

Mai Luo, Yi Xie, Jessica N. Spradlin, John A. Tallarico, Jeffrey M. McKenna +4 more

Manumycin polyketides act as molecular glues between UBR7 and P53

Nature Chemical Biology(2020)10.1038/s41589-020-0557-2

N/A

0DataRank · unranked

134 citations

Mikiko Okumura, Lynn M. McGregor, Scott M. Brittain, Michael D. Jones, Xiaoyou Liang +8 more

A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.02.022541

N/A

0DataRank · unranked

12 citations

Jessica N. Spradlin, Luiz F. T. Novaes, Erika Zhang, Xirui Hu, Malte Moeller +8 more

Targeted Protein Degradation via a Covalent Reversible Degrader Based on Bardoxolone

ChemRxiv(2020)10.26434/chemrxiv.12055935.v1

N/A

0DataRank · unranked

11 citations

Mai Luo, Yi Xie, Jessica N. Spradlin, John A. Tallarico, Jeffrey M. McKenna +4 more

Targeted Protein Degradation via a Covalent Reversible Degrader Based on Bardoxolone

ChemRxiv(2020)10.26434/chemrxiv.12055935

N/A

0DataRank · unranked

2 citations

Mai Luo, Yi Xie, Jessica N. Spradlin, John A. Tallarico, Jeffrey M. McKenna +4 more

Deubiquitinase-Targeting Chimeras for Targeted Protein Stabilization

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.30.441959

N/A

0DataRank · unranked

32 citations

Lydia Boike, Jessica N. Spradlin, Carl C. Ward, Bridget P. Belcher, Scott M. Brittain +8 more

Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.15.439993

N/A

0DataRank · unranked

22 citations

Andrew G. Manford, Jessica N. Spradlin, Scott M. Brittain, Jeffrey M. McKenna, John A. Tallarico +4 more

Deubiquitinase-targeting chimeras for targeted protein stabilization

Nature Chemical Biology(2022)10.1038/s41589-022-00971-2

N/A

0DataRank · unranked

323 citations

Lydia Boike, Jessica N. Spradlin, Carl C. Ward, Gang Liu, Erika Zhang +19 more

Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications

Journal of the American Chemical Society(2022)10.1021/jacs.1c03980

N/A

0DataRank · unranked

214 citations

Andrew G. Manford, Jessica N. Spradlin, Scott M. Brittain, Erika Zhang, Jeffrey M. McKenna +5 more

An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4

Journal of the American Chemical Society(2022)10.1021/jacs.2c04039

N/A

0DataRank · unranked

39 citations

Audrey G. Reeves, Annika C. S. Page, Patrick J. Moon, E. F. Miller, Katia Coulonval +17 more

Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design

Chemical Science(2022)10.1039/d2sc00426g

N/A

0DataRank · unranked

31 citations

Spencer O. Scholz, Katherine E. Near, Jessica N. Spradlin, Bridget P. Belcher, Scott M. Brittain +6 more

Chemoproteomics-Enabled Discovery of a Covalent Molecular Glue Degrader Targeting NF-κB

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.18.492542

N/A

0DataRank · unranked

12 citations

Yoo Jin Cho, Dustin Dovala, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle +2 more

Rational Chemical Design of Molecular Glue Degraders

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.04.512693

N/A

0DataRank · unranked

9 citations

James W. Papatzimas, Kaila Nishikawa, Dustin Dovala, Lynn M. McGregor, Matthew J. Hesse +5 more

Targeted Protein Degradation through E2 Recruitment

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.19.520812

N/A

0DataRank · unranked

7 citations

Dustin Dovala, Matthew J. Hesse, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle +2 more

An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4

ChemRxiv(2022)10.26434/chemrxiv-2022-9p94z

N/A

0DataRank · unranked

2 citations

Angel Gonzalez-Valero, Patrick J. Moon, Edward Y. Miller, Katia Coulonval, Steven W. M. Crossley +16 more

Rational Chemical Design of Molecular Glue Degraders

ACS Central Science(2023)10.1021/acscentsci.2c01317

N/A

0DataRank · unranked

185 citations

James W. Papatzimas, Kaila Nishikawa, Dustin Dovala, Andreas O. Frank, Matthew J. Hesse +13 more

Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB

(2023)10.1016/j.chembiol.2023.02.008

N/A

0DataRank · unranked

100 citations

Yoo Jin Cho, Nathan S. Hsu, Dustin Dovala, Jeffrey M. McKenna, John A. Tallarico +3 more

Targeted Protein Degradation through E2 Recruitment

ACS Chemical Biology(2023)10.1021/acschembio.3c00040

N/A

0DataRank · unranked

56 citations

Dustin Dovala, Matthew J. Hesse, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle +2 more

Ophiobolin A Covalently Targets Complex IV Leading to Mitochondrial Metabolic Collapse in Cancer Cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.09.531918

N/A

0DataRank · unranked

4 citations

Danny Q. Thach, Yangzhi Wang, Belen E. Altamirano Poblano, Dustin Dovala, John A. Tallarico +5 more

Oxidative cyclization reagents reveal tryptophan cation–π interactions

Nature(2024)10.1038/s41586-024-07140-6

N/A

0DataRank · unranked

68 citations

Patrick J. Moon, Steven W. M. Crossley, Amanda J. Bischoff, Dan He, Gen Li +9 more

Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells

ACS Chemical Biology(2024)10.1021/acschembio.4c00064

N/A

0DataRank · unranked

9 citations

Danny Q. Thach, Zhouyang Zhu, Yangzhi Wang, Belen E. Altamirano Poblano, Dustin Dovala +6 more

Sulfinyl Aziridines as Stereoselective Covalent Destabilizing Degraders of the Oncogenic Transcription Factor MYC

Angewandte Chemie International Edition(2025)10.1002/anie.202508518

N/A

0DataRank · unranked

9 citations

Kelvin Li, Christian E. Stieger, Erin L. Li, Brynne Currier, Scott M. Brittain +10 more

Sulfinyl Aziridines as Stereoselective Covalent Destabilizing Degraders of the Oncogenic Transcription Factor MYC

Angewandte Chemie(2025)10.1002/ange.202508518

N/A

0DataRank · unranked

0 citations

Kelvin Li, Christian E. Stieger, Erin L. Li, Brynne Currier, Scott M. Brittain +10 more