John A. Porco

Materials ScienceChemistryBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 37 papers. Top paper: “Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer”.

Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer

Nature Communications(2020)10.1038/s41467-020-20054-x

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0DataRank · unranked

112 citations

Hagar Lavon, Rina Wassermann-Dozorets, Meirav Pevsner‐Fischer, Shimrit Mayer, Esther Wershof +15 more

Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F

Cell Reports(2020)10.1016/j.celrep.2020.02.002

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0DataRank · unranked

77 citations

Wenhan Zhang, Regina Cencic, Patrick B. F. O’Connor, Françis Robert, William G. Devine +8 more

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

Nature Communications(2020)10.1038/s41467-020-20183-3

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71 citations

Kaddy Camara, Martin Daniel-Ivad, Richard Trilles, Sheila Marie Pimentel‐Elardo, Jen Fossen +17 more

Exploiting the Potential of Meroterpenoid Cyclases to Expand the Chemical Space of Fungal Meroterpenoids

Angewandte Chemie International Edition(2020)10.1002/anie.202011171

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41 citations

Lena Barra, Zachary Powers, Volga Kojasoy, Andrea Cheng, Feng Yang +7 more

Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen Candida auris

mBio(2020)10.1128/mbio.03329-19

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39 citations

Luke Whitesell, John A. Porco, Thomas Henkel, Lauren E. Brown, Nicole Robbins +2 more

Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis

iScience(2021)10.1016/j.isci.2021.102845

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25 citations

Shivraj M. Yabaji, Oleksii S. Rukhlenko, Bidisha Bhattacharya, Emily Waligurski, Nandini Vallavoju +9 more

A forward genetic screen identifies modifiers of rocaglate responsiveness

Scientific Reports(2021)10.1038/s41598-021-97765-8

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5 citations

Lauren Pugsley, Regina Cencic, HanChen Wang, Françis Robert, Sai Kiran Naineni +9 more

BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling

Nature Communications(2022)10.1038/s41467-022-34081-3

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83 citations

Aviad Ben‐Shmuel, Meirav Pevsner‐Fischer, Gil Friedman, Oshrat Levi-Galibov, Subhiksha Nandakumar +24 more

Unified, Asymmetric Total Synthesis of the Asnovolins and Related Spiromeroterpenoids: A Fragment Coupling Approach

Journal of the American Chemical Society(2022)10.1021/jacs.2c05366

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30 citations

John A. Porco, Feng Yang

Identification of structurally re-engineered rocaglates as inhibitors against hepatitis E virus replication

Antiviral Research(2022)10.1016/j.antiviral.2022.105359

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15 citations

Mara Klöhn, Yannick Brüggemann, Lauren E. Brown, John A. Porco, Wenhan Zhang +6 more

Inhibition of the Translation Initiation Factor eIF4A Enhances Tumor Cell Radiosensitivity

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-22-0037

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7 citations

Theresa Wechsler, Kayla Schwartz, Lauren E. Brown, John A. Porco, William G. Devine +5 more

Exploring the targeting spectrum of rocaglates among eIF4A homologs

RNA(2023)10.1261/rna.079318.122

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12 citations

Regina Cencic, Françis Robert, Lauren E. Brown, Minza Haque, Jordan Scott-Talib +5 more

Synthesis of Neocannabinoids Using Controlled Friedel–Crafts Reactions

The Journal of Organic Chemistry(2023)10.1021/acs.joc.3c01362

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8 citations

Richard Trilles, James McNeely, Lauren E. Brown, Aaron B. Beeler, John A. Porco +1 more

Asymmetric Synthesis of Nidulalin A and Nidulaxanthone A: Selective Carbonyl Desaturation Using an Oxoammonium Salt

ChemRxiv(2023)10.26434/chemrxiv-2023-ggcch

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4 citations

Richard P. Johnson, James McNeely, Md Al Faruk, John A. Porco, Kaijie Ji

Synthesis of Neocannabinoids Using Controlled Friedel-Crafts Reactions

ChemRxiv(2023)10.26434/chemrxiv-2023-7wtzg

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2 citations

Richard Trilles, James McNeely, Lauren E. Brown, Aaron B. Beeler, John A. Porco +1 more

Asymmetric Synthesis of Nidulalin A and Nidulaxanthone A: Selective Carbonyl Desaturation Using an Oxoammonium Salt

Journal of the American Chemical Society(2024)10.1021/jacs.3c13864

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15 citations

Richard P. Johnson, James McNeely, Md Al Faruk, John A. Porco, Kaijie Ji

Evolution of a Strategy for the Unified, Asymmetric Total Syntheses of DMOA-Derived Spiromeroterpenoids

The Journal of Organic Chemistry(2024)10.1021/acs.joc.4c01116

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11 citations

Amira Oladokun, John A. Porco, Feng Yang

A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen Candida albicans

Microbiology Spectrum(2024)10.1128/spectrum.04095-23

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10 citations

Dustin Duncan, Kyle D. Reichl, Michael J. Smith, Wenyu Wang, John A. Porco +5 more

The MYCN 5′ UTR as a therapeutic target in neuroblastoma

Cell Reports(2024)10.1016/j.celrep.2024.114134

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5 citations

Lauren E. Brown, Ushashi Banerjee, Ruben Dries, Bandana Sharma, Alyssa L. Kennedy +3 more

Triple-Dearomative Photocycloaddition: A Strategy to Construct Caged Molecular Frameworks

Journal of the American Chemical Society(2024)10.1021/jacs.4c02674

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9 citations

Jayachandran Parthiban, Steffen Jockusch, Jayaraman Sivaguru, John A. Porco, Kaijie Ji

Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis

Antiviral Research(2024)10.1016/j.antiviral.2024.105976

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5 citations

Wenhan Zhang, Michael Ricca, Alan Wacquiez, Autumn O Grimins, Regina Cencic +11 more

Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells

ACS Central Science(2024)10.1021/acscentsci.4c01073

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5 citations

Ritesh Thakare, Shalaka Chitale, Alok Mishra, Stanley I. Goldstein, Alice C. Fan +10 more

Glabridin Hypnosis in Zebrafish Larvae Is Associated With Effects on Multiple Anesthetic Target Receptors

Anesthesia & Analgesia(2024)10.1213/ane.0000000000007318

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1 citations

Helen M. Hoyt, Kieran Bhave, Madyson Medeiros, Daniel Cho, Lauren E. Brown +4 more

Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.19.590252

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2 citations

Alice C. Fan, Zihao Wang, Sai Kiran Naineni, Regina Cencic, Steve B. Garcia-Gutierrez +6 more

Asymmetric Synthesis of Nidulalin A and Nidulaxanthone A: Selective Carbonyl Desaturation Using an Oxoammonium Salt

ChemRxiv(2024)10.26434/chemrxiv-2023-ggcch-v2

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0DataRank · unranked

1 citations

Richard P. Johnson, James McNeely, Md Al Faruk, John A. Porco, Kaijie Ji

Triple-Dearomative Photocycloaddition – A Strategy to Construct Novel Caged Molecular Frameworks

ChemRxiv(2024)10.26434/chemrxiv-2024-150z3-v2

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1 citations

Jayachandran Parthiban, Steffen Jockusch, Jayaraman Sivaguru, John A. Porco, Kaijie Ji

In vitro discovery of a therapeutic lead for HFMD from a library screen of rocaglates/aglains

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.30.615979

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0DataRank · unranked

0 citations

Angel Borge, Regina Ching Hua Lee, Cyrill Kafi Salim, Wenyu Wang, Michael Ricca +6 more

Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays

Journal of Proteome Research(2025)10.1021/acs.jproteome.4c01129

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2 citations

Alice C. Fan, Zihao Wang, Sai Kiran Naineni, Regina Cencic, Steve B. Garcia-Gutierrez +6 more

Identification of natural products and synthetic analogs which inhibit microsporidia spores and prevent infection

Journal of Invertebrate Pathology(2025)10.1016/j.jip.2025.108492

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2 citations

Lauren E. Brown, Guoqing Pan, Junhong Wei, John A. Porco, Jie Chen +2 more

A cationic amphiphilic drug synergizes with strobilurin fungicides to control fungal-borne plant diseases

Cell chemical biology(2025)10.1016/j.chembiol.2025.05.008

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4 citations

Christopher Blackman, Mackenzie Eli William Loranger, Richard Trilles, Kalina Doytchinova-Weil, Stephen S. Scully +12 more

Connecting chemical structure to single cell signaling profiles

Communications Biology(2025)10.1038/s42003-025-08545-3

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1 citations

Madeline Hayes, Laura C. Geben, Rebecca A. Ihrie, Lauren E. Brown, John A. Porco +2 more

In Vitro Discovery of a Therapeutic Lead for HFMD From a Library Screen of Rocaglates/Aglains

Journal of Medical Virology(2025)10.1002/jmv.70228

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1 citations

Angel Borge, Regina Ching Hua Lee, Cyrill Kafi Salim, Wenyu Wang, Michael Ricca +6 more

Substrate- and Reagent-Controlled Dimerization of Vinyl para-Quinone Methides

ChemRxiv(2025)10.26434/chemrxiv-2025-m6f1l

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0DataRank · unranked

1 citations

Ryan Baker, Kyle D. Reichl, Michael J. Smith, Michael Ricca, Margaret Ann Mickelberg +1 more

Identification of natural products and synthetic analogs which inhibit microsporidia spores and prevent infection

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.06.669004

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1 citations

Lauren E. Brown, Guoqing Pan, Junhong Wei, John A. Porco, Jie Chen +2 more

Structural Basis for the Improved RNA Clamping of Amidino-Rocaglates to eIF4A1

ACS Omega(2025)10.1021/acsomega.4c09421

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0DataRank · unranked

0 citations

Lauren E. Brown, James McNeely, Jerry Pelletier, John A. Porco, Karen N. Allen +1 more

Substrate- and Reagent-Controlled Dimerization of Vinyl para-Quinone Methides

The Journal of Organic Chemistry(2025)10.1021/acs.joc.5c00123

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0DataRank · unranked

0 citations

Kyle D. Reichl, Michael J. Smith, Michael Ricca, Margaret Ann Mickelberg, John A. Porco +1 more

Asymmetric Total Synthesis of (–)-Verrucarol

ChemRxiv(2025)10.26434/chemrxiv-2025-fmd1f

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0DataRank · unranked

0 citations

Madison H. Powers, Jeffrey W. Bacon, James McNeely, John A. Porco, John F. McCleerey