Jay T. Groves

Also affiliated with University of California, Berkeley

Biochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicinePhysics and Astronomy

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 38 papers. Top paper: “Curvature-Modulated Phase Separation in Lipid Bilayer Membranes”.

Curvature-Modulated Phase Separation in Lipid Bilayer Membranes

Langmuir(2006)10.1021/la060390o

N/A

0.831DataRank · unranked

254 citations

Cheng-han Yu, Jay T. Groves, Raghuveer Parthasarathy

Stimulation of the catalytic activity of the tyrosine kinase Btk by the adaptor protein Grb2

eLife(2023)10.7554/elife.82676

N/A

0.572DataRank · unranked

16 citations

Timothy J. Eisen, Anthony T. Iavarone, Jay T. Groves, John Kuriyan, Laura M. Nocka

Membrane Association Transforms an Inert Anti-TCRβ Fab’ Ligand into a Potent T Cell Receptor Agonist

Biophysical Journal(2020)10.1016/j.bpj.2020.04.018

N/A

0.477DataRank · unranked

23 citations

Geoff P. O’Donoghue, Kiera B. Wilhelm, Michael P. Coyle, Shalini T. Low-Nam, Nicole C. Fay +3 more

Relating cellular signaling timescales to single-molecule kinetics: A first-passage time analysis of Ras activation by SOS

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2103598118

N/A

0.470DataRank · unranked

22 citations

Steven Alvarez, Yasushi Kondo, John Kuriyan, Jay T. Groves, William Y. C. Huang

Allosteric inhibition of the T cell receptor by a designed membrane ligand

eLife(2023)10.7554/elife.82861

N/A

0.312DataRank · unranked

7 citations

Shumpei Morita, Justin Chang, Patrick M Buckley, Kiera B. Wilhelm, Daniel DiMaio +3 more

Breakage of the Oligomeric CaMKII Hub by the Regulatory Segment of the Kinase

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.15.043067

N/A

0.241DataRank · unranked

4 citations

Moitrayee Bhattacharyya, Beryl Xia, Young Kwang Lee, Serena Muratcioğlu, Darren B. McAffee +6 more

Membrane-mediated dimerization potentiates PIP5K lipid kinase activity

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.21.461304

N/A

0.165DataRank · unranked

2 citations

Albert A. Lee, Jay T. Groves, Scott D. Hansen

Coupling between lipid miscibility and phosphotyrosine driven protein condensation at the membrane

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.22.215970

N/A

0DataRank · unranked

1 citations

William Y. C. Huang, Catherine B. Carbone, Laura M. Nocka, Atul N. Parikh, Ronald D. Vale +2 more

Height, but not binding epitope, affects the potency of synthetic TCR agonists

Biophysical Journal(2021)10.1016/j.bpj.2021.08.027

N/A

0DataRank · unranked

18 citations

Shumpei Morita, Darren B. McAffee, Sungi Kim, Mark K. O’Dair, Jay T. Groves +1 more

Discrete LAT condensates encode antigen information from single pMHC:TCR binding events

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.16.472676

N/A

0DataRank · unranked

12 citations

Mark K. O’Dair, Jenny J. Lin, Shalini T. Low-Nam, Kiera B. Wilhelm, Sungi Kim +3 more

Kinetic frustration by limited bond availability controls the LAT protein condensation phase transition on membranes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.05.471009

N/A

0DataRank · unranked

5 citations

Trevor GrandPre, David T. Limmer, Jay T. Groves, Simou Sun

Height, but not binding epitope, affects the potency of synthetic TCR agonists

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.13.443919

N/A

0DataRank · unranked

2 citations

Shumpei Morita, Darren B. McAffee, Sungi Kim, Mark K. O’Dair, Jay T. Groves +1 more

Probe the effect of clustering on EphA2 receptor signaling efficiency by subcellular control of ligand-receptor mobility

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.16.431455

N/A

0DataRank · unranked

0 citations

Dongmyung Oh, Kabir H. Biswas, Ronen Zaidel‐Bar, Jay T. Groves, Zhongwen Chen

A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2122531119

N/A

0DataRank · unranked

86 citations

Laura M. Nocka, Brittany Stinger, Joseph B. DeGrandchamp, L. J. Nugent Lew, Steven Alvarez +5 more

Discrete LAT condensates encode antigen information from single pMHC:TCR binding events

Nature Communications(2022)10.1038/s41467-022-35093-9

N/A

0DataRank · unranked

64 citations

Mark K. O’Dair, Jenny J. Lin, Shalini T. Low-Nam, Kiera B. Wilhelm, Sungi Kim +3 more

Patterned Substrate of Mobile and Immobile Ligands to Probe EphA2 Receptor Clustering

BIO-PROTOCOL(2022)10.21769/bioprotoc.4434

N/A

0DataRank · unranked

2 citations

Kabir H. Biswas, Jay T. Groves, Zhongwen Chen

A membrane-associated light harvesting model is enabled by functionalized assemblies of gene-doubled TMV proteins

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.08.507180

N/A

0DataRank · unranked

0 citations

Kiera B. Wilhelm, Amanda J. Bischoff, J.H. Pereira, Michel T. Dedeo, Derek García-Almedina +4 more

Coupled membrane lipid miscibility and phosphotyrosine-driven protein condensation phase transitions

Biophysical Journal(2020)10.1016/j.bpj.2020.09.017

N/A

0DataRank · unranked

76 citations

William Y. C. Huang, Catherine B. Carbone, Laura M. Nocka, Atul N. Parikh, Ronald D. Vale +2 more

A Membrane‐Associated Light‐Harvesting Model is Enabled by Functionalized Assemblies of Gene‐Doubled TMV Proteins

Small(2023)10.1002/smll.202207805

N/A

0DataRank · unranked

11 citations

Kiera B. Wilhelm, Amanda J. Bischoff, J.H. Pereira, Michel T. Dedeo, Derek García-Almedina +4 more

The impact of Grb2 on phase condensation in live cells

Biophysical Journal(2023)10.1016/j.bpj.2022.11.966

N/A

0DataRank · unranked

0 citations

Jerry Chun‐Wei Lin, Henry T. Phan, Kiera B. Wilhelm, Anand Vissa, Jay T. Groves +1 more

Bimodality in Ras signaling originates from processivity of the Ras activator SOS without classic kinetic bistability

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.17.549263

N/A

0DataRank · unranked

0 citations

Neil H. Kim, Steven Alvarez, He Ren, Joseph B. DeGrandchamp, L. J. Nugent Lew +2 more

Conditional Requirement for Dimerization of the Membrane-Binding Module of BTK

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.05.561114

N/A

0DataRank · unranked

0 citations

Sam Ghaffari-Kashani, Jay T. Groves, Arthur Weiss, John Kuriyan, Timothy J. Eisen

Differential roles of kinetic on- and off-rates in T-cell receptor signal integration revealed with a modified Fab’-DNA ligand

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2406680121

N/A

0DataRank · unranked

12 citations

Anand Vissa, Jay T. Groves, Kiera B. Wilhelm

Positive feedback in Ras activation by full-length SOS arises from autoinhibition release mechanism

Biophysical Journal(2024)10.1016/j.bpj.2024.07.014

N/A

0DataRank · unranked

6 citations

Albert A. Lee, L. J. Nugent Lew, Joseph B. DeGrandchamp, Jay T. Groves, He Ren

Proofreading and single-molecule sensitivity in T-cell receptor signaling by condensate nucleation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.13.584745

N/A

0DataRank · unranked

3 citations

David Baker, Jay T. Groves, Ariel J. Ben‐Sasson, Hao Yuan Kueh, William L. White

Differential Roles of Kinetic On- and Off-Rates in T-Cell Receptor Signal Integration Revealed with a Modified Fab’-DNA Ligand

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.01.587588

N/A

0DataRank · unranked

2 citations

Anand Vissa, Jay T. Groves, Kiera B. Wilhelm

Parallel reactions on a single T cell receptor offer a robust kinetic proofreading mechanism

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2514057122

N/A

0DataRank · unranked

8 citations

Jay T. Groves, Shumpei Morita

Proofreading and single-molecule sensitivity in T cell receptor signaling by condensate nucleation

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2422787122

N/A

0DataRank · unranked

7 citations

Hailemikael K. Yirdaw, Ariel J. Ben‐Sasson, Jay T. Groves, David Baker, Hao Yuan Kueh +1 more

Conditional requirement for dimerization of the membrane-binding module for BTK signaling in lymphocyte cell lines

Science Signaling(2025)10.1126/scisignal.ado1252

N/A

0DataRank · unranked

6 citations

Sam Ghaffari-Kashani, Chien‐Lun Hung, Jay T. Groves, Arthur Weiss, John Kuriyan +1 more

Single-molecule biophysics in signaling: Functionality from stochastic effects

Current Opinion in Cell Biology(2025)10.1016/j.ceb.2025.102597

N/A

0DataRank · unranked

2 citations

Jay T. Groves

Kinetic Proofreading through Parallel Reactions on a Single T Cell Receptor

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.01.657268

N/A

0DataRank · unranked

0 citations

Jay T. Groves, Shumpei Morita

BTK autoinhibition analyzed by high-throughput swaps of SH2 domains

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2502688122

N/A

0DataRank · unranked

0 citations

Sam Ghaffari-Kashani, Chien‐Lun Hung, Jay T. Groves, John Kuriyan, Timothy J. Eisen

A unifying model of LAT condensates in reconstitution experiments

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.31.685772

N/A

0DataRank · unranked

0 citations

Simou Sun, Mehran Kardar, Jay T. Groves, Arup K. Chakraborty, Yannick A. D. Omar

T cell costimulatory and inhibitory signals differentially modulate LAT condensate nucleation propensity after TCR ligation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.01.685673

N/A

0DataRank · unranked

0 citations

Sungi Kim, Jessica Tijham, Timothy J. Eisen, Shumpei Morita, Mark K. O’Dair +2 more

A Ran-Dependent Importin-Beta/Nup153 Barrier in the Nuclear Pore Complex

Biophysical Journal(2014)10.1016/j.bpj.2013.11.1809

N/A

0DataRank · unranked

0 citations

Alan R. Lowe, Jaime Yassif, Michael Graf, William Y.C. Huang, Jay T. Groves +3 more

EphrinB2 clustering by Nipah virus G is required to activate and trap F intermediates at supported lipid bilayer–cell interfaces

Science Advances(2021)10.1126/sciadv.abe1235

N/A

0DataRank · unranked

35 citations

Zhongwen Chen, Jean K. Chung, Jay T. Groves, Theodore S. Jardetzky, Joyce J. W. Wong

How the T cell signaling network processes information to discriminate between self and agonist ligands

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2008303117

N/A

0DataRank · unranked

64 citations

Wan‐Lin Lo, Darren B. McAffee, Jay T. Groves, Arthur Weiss, Arup K. Chakraborty +1 more

Stochasticity and positive feedback enable enzyme kinetics at the membrane to sense reaction size

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2103626118

N/A

0DataRank · unranked

24 citations

William Y. C. Huang, Scott D. Hansen, Neil H. Kim, Steven Alvarez, Jay T. Groves +1 more