Wenjie Wang

Also affiliated with Anhui Agricultural University, Xi'an University of Architecture and Technology, North China Electric Power University, Guangxi Medical University, Capital Medical University, Yuhuangding Hospital, National Clinical Research Center for Digestive Diseases, Beijing Anzhen Hospital, Beijing Institute of Water, Shanghai East Hospital, Rural Development Institute, China Agricultural University, Nanjing Medical University

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 16 papers. Top paper: “Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC)”.

Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC)

DNA repair(2020)10.1016/j.dnarep.2020.102837

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0DataRank · unranked

105 citations

Sourav Saha, Wenjie Wang, Liton Kumar Saha, Shar-yin N. Huang, Yves Pommier +1 more

The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target

Cell Reports(2020)10.1016/j.celrep.2019.12.020

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0DataRank · unranked

53 citations

Woo-Jin Shin, Bojie Zhang, Younho Choi, Ji‐Seung Yoo, Maxwell I. Zimmerman +7 more

Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I

Journal of the American Chemical Society(2020)10.1021/jacs.0c10418

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20 citations

Brice A. P. Wilson, Christophe Marchand, Suthananda N. Sunassee, Alun Bermingham, Wenjie Wang +9 more

PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation

Nature Communications(2021)10.1038/s41467-021-25252-9

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75 citations

Jiji Chen, Shar-yin N. Huang, Yijun Su, Wenjie Wang, Keli Agama +5 more

Discovery of 4-alkoxy-2-aryl-6,7-dimethoxyquinolines as a new class of topoisomerase I inhibitors endowed with potent in vitro anticancer activity

European Journal of Medicinal Chemistry(2021)10.1016/j.ejmech.2021.113261

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0DataRank · unranked

57 citations

Wagdy M. Eldehna, Wenjie Wang, Keli Agama, Yves Pommier, Manabu Abe +1 more

Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites

Chemical Science(2021)10.1039/d0sc05411a

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33 citations

Evgeny Kiselev, G.T. Lountos, Wenjie Wang, Joseph E. Tropea, D. Needle +6 more

Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00318

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28 citations

Wen-Lin Tang, Yu Zhang, Hao Yang, Wenjie Wang, Keli Agama +3 more

The synthesis of furoquinolinedione and isoxazoloquinolinedione derivatives as selective Tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors

Bioorganic Chemistry(2021)10.1016/j.bioorg.2021.104881

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11 citations

Xiaoqing Zhu, Wenjie Wang, Yu Chen, Zhu Hu, Yu Zhang +6 more

Synthesis of 11-aminoalkoxy substituted benzophenanthridine derivatives as tyrosyl-DNA phosphodiesterase 1 inhibitors and their anticancer activity

Bioorganic Chemistry(2022)10.1016/j.bioorg.2022.105789

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11 citations

Fang‐Ting Wang, Min Wu, Wenjie Wang, Keli Agama, Yves Pommier +2 more

Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1

Frontiers in Chemistry(2022)10.3389/fchem.2022.910953

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8 citations

Wenjie Wang, G.T. Lountos, Joseph E. Tropea, D. Needle, Yves Pommier +2 more

Identification and characterization of topoisomerase III beta poisons

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2218483120

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15 citations

Sourav Saha, Xi Yang, Yves Pommier, Shar-yin N. Huang, Wenjie Wang

Synthesis and Biological Activities of 11‐ and 12‐Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl‐DNA Phosphodiesterase 1 Inhibitors

ChemMedChem(2023)10.1002/cmdc.202200593

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10 citations

Chao Qin, Min Wu, Fang‐Ting Wang, Wenjie Wang, Keli Agama +4 more

Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification

RSC Chemical Biology(2023)10.1039/d2cb00230b

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0DataRank · unranked

10 citations

Wenjie Wang, G.T. Lountos, Evgeny Kiselev, Joseph E. Tropea, D. Needle +3 more

Targeted sulfur(VI) fluoride exchange-mediated covalent modification of a tyrosine residue in the catalytic pocket of tyrosyl-DNA phosphodiesterase 1

Communications Chemistry(2024)10.1038/s42004-024-01298-w

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7 citations

I Barakat, G.T. Lountos, Wenjie Wang, Keli Agama, Md Rasel Al Mahmud +5 more

Application of a bivalent “click” approach to target tyrosyl-DNA phosphodiesterase 1 (TDP1)

RSC Medicinal Chemistry(2025)10.1039/d4md00824c

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4 citations

Wenjie Wang, Md Rasel Al Mahmud, Keli Agama, Yves Pommier, Terrence R. Burke +1 more

Potent β-lactam-based tyrosyl-DNA phosphodiesterase 1 inhibitors identified by a virtual screen

Scientific Reports(2025)10.1038/s41598-025-12503-8

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0DataRank · unranked

1 citations

Wenjie Wang, Kiall F. Suazo, Md Rasel Al Mahmud, Keli Agama, G.T. Lountos +4 more