Christopher C.W. Hughes

Biochemistry, Genetics and Molecular BiologyEngineeringMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 26 papers. Top paper: “Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis”.

Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis

Nature Communications(2020)10.1038/s41467-020-18633-z

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0DataRank · unranked

101 citations

Jennifer S. Fang, Mary E. Ziegler, Ricardo N. Ramírez, Duc T. T. Phan, Michaela M.S. Hatch +8 more

Human in vitro vascularized micro-organ and micro-tumor models are reproducible organ-on-a-chip platforms for studies of anticancer drugs

Toxicology(2020)10.1016/j.tox.2020.152601

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0DataRank · unranked

47 citations

Courtney Sakolish, Zunwei Chen, Duc T. T. Phan, R. Hugh F. Bender, Christopher C.W. Hughes +2 more

An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy

Lab on a Chip(2021)10.1039/d0lc01216e

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0DataRank · unranked

126 citations

Silva Movsesyan, Quy Nguyen, Giselle Burton-Sojo, Ani Tankazyan, Jie Wu +17 more

Tumor-on-chip modeling of organ-specific cancer and metastasis

Advanced Drug Delivery Reviews(2021)10.1016/j.addr.2021.05.008

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0DataRank · unranked

125 citations

Venktesh S. Shirure, Ye Bi, S. Peter Goedegebuure, Sepideh Gholami, Christopher C.W. Hughes +3 more

Regulation of Partial and Reversible Endothelial-to-Mesenchymal Transition in Angiogenesis

Frontiers in Cell and Developmental Biology(2021)10.3389/fcell.2021.702021

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0DataRank · unranked

63 citations

Nan W. Hultgren, Christopher C.W. Hughes, Jennifer S. Fang

A modular microfluidic system based on a multilayered configuration to generate large-scale perfusable microvascular networks

Microsystems & Nanoengineering(2021)10.1038/s41378-020-00229-8

N/A

0DataRank · unranked

53 citations

Zhao Da, Duc T. T. Phan, Xiaolin Wang, Joshua Jonghyun Park, Zayn Biviji +3 more

The vascular niche in next generation microphysiological systems

Lab on a Chip(2021)10.1039/d1lc00530h

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0DataRank · unranked

42 citations

Yu-Hsi Chen, Abraham P. Lee, Christopher C.W. Hughes, Makena L. Ewald

A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.21.473744

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0DataRank · unranked

8 citations

Benjamen O’Donnell, Bhupinder Shergill, Brittany Q Pham, Damie J. Juat, M. S. Hatch +11 more

Structure-based Design of CDC42 Effector Interaction Inhibitors For the Treatment of Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.14.464305

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0DataRank · unranked

1 citations

José Antonio Ortega, Linh M. Vuong, Isabella Maria Acquistapace, Stephanie J. Hachey, Jessica L. Flesher +17 more

A human vascularized microtumor model of patient-derived colorectal cancer recapitulates clinical disease

Translational research(2022)10.1016/j.trsl.2022.11.011

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0DataRank · unranked

31 citations

Agua Sobrino, John G. Lee, Mehraneh D. Jafari, Samuel J. Klempner, Eric J. Puttock +6 more

Adoptive T-Cell Therapy in Advanced Colorectal Cancer: A Systematic Review

The Oncologist(2022)10.1093/oncolo/oyab038

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0DataRank · unranked

25 citations

Stephanie J. Hachey, John Billimek, Michael P. Del Rosario, Edward L. Nelson, Christopher C.W. Hughes +2 more

Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer

Cell Reports(2022)10.1016/j.celrep.2022.110641

N/A

0DataRank · unranked

19 citations

José Antonio Ortega, Linh M. Vuong, Isabella Maria Acquistapace, Stephanie J. Hachey, Jessica L. Flesher +17 more

Organotypic stromal cells impact endothelial cell transcriptome in 3D microvessel networks

Scientific Reports(2022)10.1038/s41598-022-24013-y

N/A

0DataRank · unranked

16 citations

Natalie H. Kelly, Christopher C.W. Hughes, Steven C. George, Matthew B. Curtis

Deconstructing Allograft Adipose and Fascia Matrix: Fascia Matrix Improves Angiogenesis, Volume Retention, and Adipogenesis in a Rodent Model

Plastic & Reconstructive Surgery(2022)10.1097/prs.0000000000009794

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0DataRank · unranked

13 citations

Alexandria M. Sorensen, Derek A. Banyard, Lohrasb Sayadi, Evangelia Chnari, Michaela M.S. Hatch +7 more

Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.28.513298

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0DataRank · unranked

9 citations

Yesl Jun, Somesh Sai, R. Hugh F. Bender, Vira Kravets, Han Zhu +10 more

A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction

Biofabrication(2023)10.1088/1758-5090/ad17d0

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0DataRank · unranked

33 citations

Benjamen O’Donnell, Bhupinder Shergill, Brittany Q Pham, Sima Tahmouresie, Celeste N Sanchez +13 more

A novel platform to enrich for tumor-specific T cells in non–small-cell lung cancer.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.2556

N/A

0DataRank · unranked

0 citations

Alexander G. Forsythe, Ali Mahtabifard, Hari B. Keshava, Christopher C.W. Hughes, Stephanie J. Hachey

Targeting tumor-stromal interactions in triple-negative breast cancer using a human vascularized micro-tumor model

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.06.556584

N/A

0DataRank · unranked

0 citations

Christopher J. Hatch, Daniela Gaebler, Aneela Mocherla, Kevin Nee, Kai Kessenbrock +2 more

Targeting tumor–stromal interactions in triple-negative breast cancer using a human vascularized micro-tumor model

Breast Cancer Research(2024)10.1186/s13058-023-01760-y

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0DataRank · unranked

21 citations

Christopher J. Hatch, Daniela Gaebler, Aneela Mocherla, Kevin Nee, Kai Kessenbrock +2 more

Microphysiological systems as models for immunologically ‘cold’ tumors

Frontiers in Cell and Developmental Biology(2024)10.3389/fcell.2024.1389012

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0DataRank · unranked

11 citations

Stephanie J. Hachey, Christopher C.W. Hughes, Daniela Gaebler

Fundamental considerations for designing endothelialized in vitro models of thrombosis

Thrombosis Research(2024)10.1016/j.thromres.2024.03.004

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0DataRank · unranked

8 citations

Vanessa Bröker, Minke Rijpkema, Christopher C.W. Hughes, Leon J. Schurgers, Judith M.E.M. Cosemans +1 more

SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system

Frontiers in Cardiovascular Medicine(2024)10.3389/fcvm.2024.1360364

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0DataRank · unranked

7 citations

Sebastian D. Piombo, Jennifer S. Fang, Johannes S. Gach, Makena L. Ewald, William K. Van Trigt +5 more

A Microphysiological HHT-on-a-Chip Platform Recapitulates Patient Vascular Lesions

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.11.584490

N/A

0DataRank · unranked

3 citations

Christopher J. Hatch, Jillian W. Andrejecsk, William Van Trigt, Damie J. Juat, Yu‐Hsi Chen +4 more

Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids

Developmental Cell(2025)10.1016/j.devcel.2025.04.024

N/A

0DataRank · unranked

23 citations

Kim-Vy Nguyen-Ngoc, Somesh Sai, R. Hugh F. Bender, Winnie Gong, Vira Kravets +11 more

ImmuniT Platform for Improved Neoantigen Prediction in Lung Cancer

Vaccines(2025)10.3390/vaccines13090921

N/A

0DataRank · unranked

1 citations

Alexander G. Forsythe, Hari B. Keshava, Christopher C.W. Hughes, Stephanie J. Hachey

A vascular-associated fibroblastic cell controls pancreatic islet immunity

Cell Reports(2025)10.1016/j.celrep.2025.116189

N/A

0DataRank · unranked

0 citations

Anne Costanzo, Siddhartha Sharma, Lisa Kain, Kelley W. Moremen, Jeremy Pettus +9 more