David A. Lewis

Also affiliated with UPMC Health System, University of Pittsburgh Medical Center

NeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

7.5Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Scientific Data(2020)10.1038/s41597-020-00642-8

Top 3%

6.5DataRank

Top 3%331 citations

Thanneer M. Perumal, Minerva M. Carrasquillo, Mariet Allen, Joseph S. Reddy, Gabriel E. Hoffman +95 more

Papers

Driven by 61 papers — median percentile 88. Top paper: “Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions”.

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Scientific Data(2020)10.1038/s41597-020-00642-8

Top 3%

6.5DataRank

Top 3%331 citations

Thanneer M. Perumal, Minerva M. Carrasquillo, Mariet Allen, Joseph S. Reddy, Gabriel E. Hoffman +95 more

Pan-cancer proteogenomics characterization of tumor immunity

Cell(2024)10.1016/j.cell.2024.01.027

N/A

1.7DataRank · unranked

91 citations

Weiping Ma, Tomer M. Yaron, Francesca Pia Caruso, Nicole Tignor, Joshua M. Wang +95 more

Functional annotation of rare structural variation in the human brain

Nature Communications(2020)10.1038/s41467-020-16736-1

N/A

1.7DataRank · unranked

54 citations

Xuefang Zhao, Mary Lauren Benton, Thanneer M. Perumal, Ryan L. Collins, Gabriel E. Hoffman +65 more

Population-level variation in enhancer expression identifies disease mechanisms in the human brain

Nature Genetics(2022)10.1038/s41588-022-01170-4

N/A

1.1DataRank · unranked

53 citations

Gabriel E. Hoffman, Pasha Apontes, Jaroslav Bendl, Samir Rahman, Michael B. Fernando +48 more

Single nuclei transcriptomics in human and non-human primate striatum in opioid use disorder

Nature Communications(2024)10.1038/s41467-024-45165-7

N/A

1.1DataRank · unranked

53 citations

Madelyn H. Ray, Xiangning Xue, Chen Fu, Robert J. Fenster, Stephen J. Kohut +17 more

Diurnal rhythms across the human dorsal and ventral striatum

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2016150118

Top 21%

0.967DataRank

Top 21%48 citations

Wei Zong, Mariah A. Hildebrand, Marianne L. Seney, Kelly Cahill, Madeline R. Scott +6 more

Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains

Nature Neuroscience(2022)10.1038/s41593-022-01032-6

N/A

0.644DataRank · unranked

72 citations

Gabriel E. Hoffman, Jaroslav Bendl, Samir Rahman, Pengfei Dong, Will Liao +30 more

Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition

Cell Reports(2024)10.1016/j.celrep.2024.114876

N/A

0.570DataRank · unranked

22 citations

Michael J. Leone, Michael Kleyman, Alexander Chamessian, Myung‐chul Noh, BaDoi N. Phan +20 more

Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder

Translational Psychiatry(2021)10.1038/s41398-021-01290-1

N/A

0.524DataRank · unranked

32 citations

Lora McClain, Lambertus Klei, Jiebiao Wang, Brittany L. Chamberlain, Sara A. Springer +4 more

Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits

Frontiers in Neuroanatomy(2020)10.3389/fnana.2020.578483

N/A

0.520DataRank · unranked

31 citations

John F. Enwright, Dominique Arion, Constantinos D. Paspalas, Yury M. Morozov, David A. Lewis +2 more

Omics Approaches to Investigate the Pathogenesis of Suicide

Biological Psychiatry(2024)10.1016/j.biopsych.2024.05.017

N/A

0.473DataRank · unranked

10 citations

Yang Xiao, Tarjinder Singh, Chenxu Zhu, Mbemba Jabbi, Harry Pantazopoulos +16 more

Laminar Differences in the Targeting of Dendritic Spines by Cortical Pyramidal Neurons and Interneurons in Human Dorsolateral Prefrontal Cortex

Neuroscience(2020)10.1016/j.neuroscience.2020.10.022

N/A

0.345DataRank · unranked

9 citations

Dibyadeep Datta, Kenneth N. Fish, Daniel W. Chung, Darlene S. Melchitzky, David A. Lewis +1 more

Comparative Pathway Integrator: A Framework of Meta-Analytic Integration of Multiple Transcriptomic Studies for Consensual and Differential Pathway Analysis

Genes(2020)10.3390/genes11060696

N/A

0.330DataRank · unranked

8 citations

Wei Zong, Chien-Wei Lin, Zhou Fang, Tianzhou Ma, David A. Lewis +3 more

Genetic regulation of cell-type specific chromatin accessibility shapes the etiology of brain diseases

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.02.530826

N/A

0.330DataRank · unranked

7 citations

Jaroslav Bendl, Chengyu Deng, Donghoon Lee, Ruth Misir, Sarah Reach +10 more

The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development

medRxiv(2023)10.1101/2023.10.02.23296067

N/A

0.292DataRank · unranked

6 citations

Jaroslav Bendl, Andrew Baumgartner, Karen Therrien, Sanan Venkatesh, Deepika Mathur +15 more

Altered excitatory and inhibitory ionotropic receptor subunit expression in the cortical visuospatial working memory network in schizophrenia

Neuropsychopharmacology(2024)10.1038/s41386-024-01854-x

N/A

0.269DataRank · unranked

5 citations

Samuel J. Dienel, H. Holly Bazmi, John F. Enwright, David A. Lewis, Kirsten E. Schoonover

The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development

Research Square(2023)10.21203/rs.3.rs-3393581/v1

N/A

0.241DataRank · unranked

4 citations

Jaroslav Bendl, Andrew Baumgartner, Karen Therrien, Sanan Venkatesh, Deepika Mathur +15 more

Aging disrupts the coordination between mRNA and protein expression in mouse and human midbrain

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.01.596950

N/A

0.208DataRank · unranked

3 citations

Samuel J. Mabry, Jill R. Glausier, Tabitha Banks‐Tibbs, Caroline Ward, Jenesis Gayden +6 more

Acetylated Chromatin Domains Link Chromosomal Organization to Cell- and Circuit-level Dysfunction in Schizophrenia and Bipolar Disorder

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.02.446728

N/A

0.165DataRank · unranked

2 citations

Gabriel E. Hoffman, Jaroslav Bendl, Samir Rahman, Pengfei Dong, Will Liao +28 more

VGLUT modulates sex differences in dopamine neuron vulnerability to age-related neurodegeneration

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.11.379008

N/A

0.165DataRank · unranked

2 citations

Thomas Steinkellner, Despoina Aslanoglou, Michael Villeneuve, Sai H. Bhatte, Victoria C. Childers +17 more

Mapping DNA Methylation Signatures to Identify Epigenetic Variation Across Subcortical Regions of the Human Posttraumatic Stress Disorder Brain

Biological Psychiatry(2025)10.1016/j.biopsych.2025.10.032

N/A

0.104DataRank · unranked

1 citations

Yujing Liu, Yiming Shi, Jiawei Wang, Tuan Nguyen, Yuhan Xie +30 more

Molecular rhythm alterations in prefrontal cortex and nucleus accumbens associated with opioid use disorder

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.07.463568

N/A

0DataRank · unranked

3 citations

Wei Zong, Jill R. Glausier, Sam-Moon Kim, Micah A. Shelton, BaDoi N. Phan +7 more

Fine-mapping reveals novel alternative splicing of the dopamine transporter

UNC Libraries(2020)10.17615/sbyt-hc58

N/A

0DataRank · unranked

0 citations

Pramod Thomas, Joel Wood, Michael Chen, A. Javier Lopez, Annie Watson +21 more

Kcns3 Deficiency Disrupts Parvalbumin Neuron Physiology in Mouse Prefrontal Cortex: Implications for the pathophysiology of schizophrenia

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.02.280107

N/A

0DataRank · unranked

0 citations

Takanori Hashimoto, Monica Abraham, Rika Kawabata, Sho Koshikizawa, Yufan Bian +5 more

Molecular rhythm alterations in prefrontal cortex and nucleus accumbens associated with opioid use disorder

Translational Psychiatry(2022)10.1038/s41398-022-01894-1

N/A

0DataRank · unranked

35 citations

Wei Zong, Jill R. Glausier, Sam-Moon Kim, Micah A. Shelton, BaDoi N. Phan +7 more

Schizophrenia-associated differential DNA methylation in brain is distributed across the genome and annotated to MAD1L1, a locus at which DNA methylation and transcription phenotypes share genetic variation with schizophrenia risk

Translational Psychiatry(2022)10.1038/s41398-022-02071-0

N/A

0DataRank · unranked

29 citations

Lora McClain, Christopher Hensler, Yue Wei, Lambertus Klei, David A. Lewis +5 more

Diurnal Alterations in Gene Expression Across Striatal Subregions in Psychosis

Biological Psychiatry(2022)10.1016/j.biopsych.2022.08.013

N/A

0DataRank · unranked

23 citations

Wei Zong, Mariah A. Hildebrand, Madeline R. Scott, Marianne L. Seney, Kelly Cahill +6 more

Differential gene expression between callosal and ipsilateral projection neurons in the monkey dorsolateral prefrontal and posterior parietal cortices

Cerebral Cortex(2022)10.1093/cercor/bhac157

N/A

0DataRank · unranked

19 citations

John F. Enwright, Guillermo González‐Burgos, David A. Lewis, Dominique Arion

Laminar-Specific Alterations in Calbindin-Positive Boutons in the Prefrontal Cortex of Subjects With Schizophrenia

Biological Psychiatry(2022)10.1016/j.biopsych.2022.12.004

N/A

0DataRank · unranked

6 citations

Brad R. Rocco, James Wilson, David A. Lewis, Kenneth N. Fish

Spatial, transcriptomic and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.01.486135

N/A

0DataRank · unranked

5 citations

Michael J. Leone, Michael Kleyman, Alexander Chamessian, BaDoi N. Phan, Bettega Costa Lopes +19 more

Mechanisms regulating the frequency of inhibition-based gamma oscillations in primate prefrontal and parietal cortices

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.26.489470

N/A

0DataRank · unranked

0 citations

Takeaki Miyamae, Nita Reddy, Sidney Dawkins, Chloe Chen, Avyi Hill +4 more

The Nature of Prefrontal Cortical GABA Neuron Alterations in Schizophrenia: Markedly Lower Somatostatin and Parvalbumin Gene Expression Without Missing Neurons

American Journal of Psychiatry(2023)10.1176/appi.ajp.20220676

N/A

0DataRank · unranked

68 citations

Kenneth N. Fish, David A. Lewis, Samuel J. Dienel

Circadian rhythm disruptions associated with opioid use disorder in synaptic proteomes of human dorsolateral prefrontal cortex and nucleus accumbens

Molecular Psychiatry(2023)10.1038/s41380-023-02241-6

N/A

0DataRank · unranked

19 citations

Xiangning Xue, Ryan Salisbury, Micah A. Shelton, Sam-Moon Kim, Mariah A. Hildebrand +9 more

Localization and Diagnostic Specificity of Glutamic Acid Decarboxylase Transcript Alterations in the Dorsolateral Prefrontal Cortex in Schizophrenia

Biological Psychiatry(2023)10.1016/j.biopsych.2023.04.003

N/A

0DataRank · unranked

11 citations

Samuel J. Dienel, Zackery J. Barile, H. Holly Bazmi, David A. Lewis, Kevin Dowling

Altered Rbfox1-Vamp1 pathway and prefrontal cortical dysfunction in schizophrenia

Research Square(2023)10.21203/rs.3.rs-2944372/v1

N/A

0DataRank · unranked

8 citations

Samuel J. Dienel, Matthew Belch, Kenneth N. Fish, G. Bard Ermentrout, David A. Lewis +2 more

Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.23.216697

N/A

0DataRank · unranked

3 citations

Lora McClain, Lambertus Klei, Jiebiao Wang, Brittany L. Chamberlain, Sara A. Springer +4 more

Circadian rhythm disruptions associated with opioid use disorder in the synaptic proteomes of the human dorsolateral prefrontal cortex and nucleus accumbens

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.07.536056

N/A

0DataRank · unranked

5 citations

Xiangning Xue, Ryan Salisbury, Micah A. Shelton, Sam-Moon Kim, Mariah A. Hildebrand +9 more

Unpacking Unstructured Data: A Pilot Study on Extracting Insights from Neuropathological Reports of Parkinson’s Disease Patients using Large Language Models

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.12.557252

N/A

0DataRank · unranked

5 citations

Amber Schedlbauer, Emily Lorenzen, Alex Kadhim, A. Lobanova, David A. Lewis +2 more

Cryo-FIB workflow for imaging brain tissue via in situ cryo-electron microscopy

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.11.528064

N/A

0DataRank · unranked

2 citations

Jill R. Glausier, Chyongere Hsieh, Thomas Schmelzer, Silas A. Buck, Jonathan Franks +5 more

Postnatal Development of Glutamate and GABA Transcript Expression in Monkey Visual, Parietal, and Prefrontal Cortices

Cerebral Cortex(2020)10.1093/cercor/bhaa342

N/A

0DataRank · unranked

8 citations

H. Holly Bazmi, Andrew J Ciesielski, Liban A Dinka, Kehui Chen, David A. Lewis +1 more

Older molecular brain age in severe mental illness

Molecular Psychiatry(2020)10.1038/s41380-020-0834-1

N/A

0DataRank · unranked

54 citations

Lun‐Ching Chang, Tianzhou Ma, Hyunjung Oh, Beverly J. French, Rachel Puralewski +16 more

Unpacking unstructured data: A pilot study on extracting insights from neuropathological reports of Parkinson’s Disease patients using large language models

Biology Methods and Protocols(2024)10.1093/biomethods/bpae072

N/A

0DataRank · unranked

15 citations

Amber Schedlbauer, Emily Lorenzen, Alex Kadhim, A. Lobanova, David A. Lewis +2 more

Altered Rbfox1-Vamp1 pathway and prefrontal cortical dysfunction in schizophrenia

Molecular Psychiatry(2024)10.1038/s41380-024-02417-8

N/A

0DataRank · unranked

11 citations

Samuel J. Dienel, Matthew Belch, Kenneth N. Fish, G. Bard Ermentrout, David A. Lewis +2 more

Cell Type–Specific Profiles and Developmental Trajectories of Transcriptomes in Primate Prefrontal Layer 3 Pyramidal Neurons: Implications for Schizophrenia

American Journal of Psychiatry(2024)10.1176/appi.ajp.20230541

N/A

0DataRank · unranked

5 citations

John F. Enwright, Guillermo González‐Burgos, David A. Lewis, Dominique Arion

Alterations in inhibitory neuron subtype-selective transcripts in the prefrontal cortex: comparisons across schizophrenia and mood disorders

Psychological Medicine(2024)10.1017/s0033291724002344

N/A

0DataRank · unranked

3 citations

Sohei Kimoto, Rika Kawabata, Yufan Bian, Makoto Tsubomoto, Kazuya Okamura +5 more

Disentangling transcriptomic heterogeneity within the human subgenual anterior cingulate cortex

Cerebral Cortex(2024)10.1093/cercor/bhae291

N/A

0DataRank · unranked

2 citations

Micah A. Shelton, RuoFei Yin, Michael T. Gorczyca, Wei Zong, Jill R. Glausier +5 more

Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.26.582174

N/A

0DataRank · unranked

2 citations

Cédric Bouchet‐Marquis, Matthew Maier, Tabitha Banks‐Tibbs, Ken Wu, Jiying Ning +4 more

Synaptic alterations in pyramidal cells following genetic manipulation of neuronal excitability in monkey prefrontal cortex

Journal of Neurophysiology(2024)10.1152/jn.00326.2024

N/A

0DataRank · unranked

0 citations

Takeaki Miyamae, Yosuke Nishihata, Olga L Krimer, Kirsten Wade, Kenneth N. Fish +6 more

Alterations in Prefrontal Cortical Somatostatin Neurons in Schizophrenia: Evidence for Weaker Inhibition of Pyramidal Neuron Dendrites

Biological Psychiatry(2025)10.1016/j.biopsych.2025.01.010

N/A

0DataRank · unranked

5 citations

Kirsten Wade, Kenneth N. Fish, David A. Lewis, Samuel J. Dienel

A multi-omic approach implicates novel protein dysregulation in post-traumatic stress disorder

Genome Medicine(2025)10.1186/s13073-025-01473-1

N/A

0DataRank · unranked

5 citations

Yujing Liu, Hongyu Li, Tuan P. Nguyen, John Lee Soto-Vargas, Rashaun S. Wilson +41 more

Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex

iScience(2025)10.1016/j.isci.2025.112747

N/A

0DataRank · unranked

3 citations

Matthew Maier, Cédric Bouchet‐Marquis, Ken Wu, Tabitha Banks‐Tibbs, Darlene S. Melchitzky +4 more

Sex and regional differences in gene expression across the striatum in psychosis

Translational Psychiatry(2025)10.1038/s41398-025-03395-3

N/A

0DataRank · unranked

2 citations

RuoFei Yin, Madeline R. Scott, Wei Zong, Marianne L. Seney, Xiangning Xue +8 more

Aging disrupts the coordination between mRNA and protein expression in mouse and human midbrain

Molecular Psychiatry(2025)10.1038/s41380-025-02909-1

N/A

0DataRank · unranked

4 citations

Samuel J. Mabry, Jill R. Glausier, Tabitha Banks‐Tibbs, Caroline Ward, Jenesis Gayden +6 more

CircRNA hypomethylation in the human amygdala implicates FKBP5 in alcohol use disorder

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.04.652083

N/A

0DataRank · unranked

1 citations

Jill R. Glausier, Arun Asok, Michelle R. Doyle, P. Campo, Luca Colnaghi +7 more

Altered Markers of Tonic Inhibition in the Dorsolateral Prefrontal Cortex of Subjects With Schizophrenia

UNC Libraries(2020)10.17615/bbqb-yh84

N/A

0DataRank · unranked

0 citations

Jaime G. Maldonado‐Avilés, David W. Volk, A. Leslie Morrow, Allison A. Curley, David A. Lewis +3 more

Transcriptomes of higher order thalamic nuclei in obsessive compulsive disorder

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.22.650032

N/A

0DataRank · unranked

0 citations

Rishi Deshmukh, Lambertus Klei, Bernie Devlin, Jill R. Glausier, David A. Lewis +2 more

Mechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia

Neuropsychopharmacology(2021)10.1038/s41386-021-01089-0

N/A

0DataRank · unranked

234 citations

Samuel J. Dienel, David A. Lewis, Cameron S. Carter, Jason Smucny

Gene expression elucidates functional impact of polygenic risk for schizophrenia

UNC Libraries(2020)10.17615/k6wj-s665

N/A

0DataRank · unranked

0 citations

Edwin C. Oh, Eli A. Stahl, David A. Bennett, Nicholas Katsanis, Tymor Hamamsy +53 more

Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus

Journal of Neuroscience(2021)10.1523/jneurosci.2197-20.2021

N/A

0DataRank · unranked

32 citations

Chelsea E. Lee, Stephanie A. Zlatic, A. Freeman, Nicole Shearing, Cortnie Hartwig +15 more

Involvement of the nuclear factor-κB transcriptional complex in prefrontal cortex immune activation in bipolar disorder

Translational Psychiatry(2021)10.1038/s41398-020-01092-x

N/A

0DataRank · unranked

20 citations

Aaron Jenkins, David A. Lewis, David W. Volk, Kaitlyn M. Roman

Kcns3 deficiency disrupts Parvalbumin neuron physiology in mouse prefrontal cortex: Implications for the pathophysiology of schizophrenia

Neurobiology of Disease(2021)10.1016/j.nbd.2021.105382

N/A

0DataRank · unranked

19 citations

Takanori Hashimoto, Monica Abraham, Rika Kawabata, Sho Koshikizawa, Yufan Bian +6 more

David A. Lewis

Indexed papers

Top data-sharing exemplar

Papers