Heather Francis

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 52 papers. Top paper: “Kupffer Cells”.

Kupffer Cells

American Journal Of Pathology(2020)10.1016/j.ajpath.2020.08.014

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154 citations

Leonardo Baiocchi, Nan Wu, Burcin Ekser, Keisaku Sato, Emily Lin +15 more

Indole Alleviates Diet‐Induced Hepatic Steatosis and Inflammation in a Manner Involving Myeloid Cell 6‐Phosphofructo‐2‐Kinase/Fructose‐2,6‐Biphosphatase 3

Hepatology(2020)10.1002/hep.31115

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140 citations

Honggui Li, Jinbo Hu, Juan Zheng, Jing Zhou, Rachel Botchlett +14 more

Melatonin and circadian rhythms in liver diseases: Functional roles and potential therapies

Journal of Pineal Research(2020)10.1111/jpi.12639

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104 citations

Fanyin Meng, Heather Francis, Nan Wu, Lixian Chen, Lindsey Kennedy +7 more

The interplay between mast cells, pineal gland, and circadian rhythm: Links between histamine, melatonin, and inflammatory mediators

Journal of Pineal Research(2020)10.1111/jpi.12699

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66 citations

Leonardo Baiocchi, Lindsey Kennedy, Keisaku Sato, Vik Meadows, Fanyin Meng +7 more

Mast Cells Induce Ductular Reaction Mimicking Liver Injury in Mice Through Mast Cell–Derived Transforming Growth Factor Beta 1 Signaling: [RETRACTED]

Hepatology(2020)10.1002/hep.31497

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57 citations

Lindsey Kennedy, Vik Meadows, Laura Hargrove, Jennifer Demieville, Linh Pham +7 more

The Dynamic Interplay Between Mast Cells, Aging/Cellular Senescence, and Liver Disease

Gene Expression(2020)10.3727/105221620x15960509906371

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26 citations

Lindsey Kennedy, Vik Meadows, Leonardo Baiocchi, Gianfranco Alpini, Heather Francis +1 more

Cholangiocarcinoma: bridging the translational gap from preclinical to clinical development and implications for future therapy

Expert Opinion on Investigational Drugs(2020)10.1080/13543784.2021.1854725

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17 citations

Keisaku Sato, Burcin Ekser, Lindsey Kennedy, Heather Francis, Ludovica Ceci +10 more

Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment

American Journal Of Pathology(2020)10.1016/j.ajpath.2020.01.013

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15 citations

Vik Meadows, Konstantina Kyritsi, Linh Pham, Debjyoti Kundu, Rewa Kulkarni +9 more

Neuroendocrine Changes in Cholangiocarcinoma Growth

Cells(2020)10.3390/cells9020436

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8 citations

Heather Francis, Tianhao Zhou, Fanyin Meng, Lindsey Kennedy, Burcin Ekser +8 more

Knockout of the Tachykinin Receptor 1 in the Mdr2−/− (Abcb4−/−) Mouse Model of Primary Sclerosing Cholangitis Reduces Biliary Damage and Liver Fibrosis

American Journal Of Pathology(2020)10.1016/j.ajpath.2020.07.007

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12 citations

Heather Francis, Tianhao Zhou, Thao Giang, Zhihong Yang, Fanyin Meng +15 more

Concise Review: Functional Roles and Therapeutic Potentials of Long Non-coding RNAs in Cholangiopathies

Frontiers in Medicine(2020)10.3389/fmed.2020.00048

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10 citations

Shannon Glaser, Heather Francis, Gianfranco Alpini, Keisaku Sato

Functional Role of the Secretin/Secretin Receptor Signaling During Cholestatic Liver Injury

Hepatology(2020)10.1002/hep.31484

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37 citations

Leonardo Baiocchi, Tianhao Zhou, Lindsey Kennedy, Ludovica Ceci, Fanyin Meng +16 more

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases

Frontiers in Medicine(2020)10.3389/fmed.2020.00015

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31 citations

Lindsey Kennedy, Debjyoti Kundu, Gianfranco Alpini, Heather Francis, Vik Meadows

Downregulation of p16 Decreases Biliary Damage and Liver Fibrosis in the Mdr2 / Mouse Model of Primary Sclerosing Cholangitis

Gene Expression(2020)10.3727/105221620x15889714507961

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28 citations

Heather Francis, Tianhao Zhou, Ludovica Ceci, Nan Wu, Zhihong Yang +10 more

Doublecortin‐Like Kinase Protein 1 in Cholangiocarcinoma: Is This the Biomarker and Target We Have Been Looking For?

Hepatology(2020)10.1002/hep.31630

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4 citations

Heather Francis, Vik Meadows

Correction to: Knockout of α-calcitonin gene-related peptide attenuates cholestatic liver injury by differentially regulating cellular senescence of hepatic stellate cells and cholangiocytes

Laboratory Investigation(2020)10.1038/s41374-020-0376-9

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0 citations

Ludovica Ceci, Nan Wu, Tianhao Zhou, Lixian Chen, Julie Venter +12 more

Mast Cells Regulate Ductular Reaction and Intestinal Inflammation in Cholestasis Through Farnesoid X Receptor Signaling

Hepatology(2021)10.1002/hep.32028

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82 citations

Lindsey Kennedy, Burcin Ekser, Konstantina Kyritsi, Debjyoti Kundu, Tianhao Zhou +9 more

Mast Cells Promote Nonalcoholic Fatty Liver Disease Phenotypes and Microvesicular Steatosis in Mice Fed a Western Diet

Hepatology(2021)10.1002/hep.31713

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54 citations

Vik Meadows, Amelia Sybenga, Jennifer Demieville, Lixian Chen, Laura Hargrove +12 more

Heterogeneity of Hepatic Stellate Cells in Fibrogenesis of the Liver: Insights from Single-Cell Transcriptomic Analysis in Liver Injury

Cells(2021)10.3390/cells10082129

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57 citations

Simon J. Conway, Ying Liu, Paige Snider, Hanying Chen, Hongyu Gao +10 more

Inhibition of Secretin/Secretin Receptor Axis Ameliorates NAFLD Phenotypes

Hepatology(2021)10.1002/hep.31871

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41 citations

Nan Wu, Lindsey Kennedy, Heather Francis, Ludovica Ceci, Tianhao Zhou +11 more

Melatonin receptor 1A, but not 1B, knockout decreases biliary damage and liver fibrosis during cholestatic liver injury

Hepatology(2021)10.1002/hep.32233

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39 citations

Guido Carpino, Ludovica Ceci, Leonardo Baiocchi, Heather Francis, Lindsey Kennedy +13 more

Biliary Epithelial Senescence in Liver Disease: There Will Be SASP

Frontiers in Molecular Biosciences(2021)10.3389/fmolb.2021.803098

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34 citations

Leonardo Baiocchi, Debjyoti Kundu, Keisaku Sato, Yessenia Fuentes, Chaodong Wu +6 more

Adipose tissue inflammation and systemic insulin resistance in mice with diet-induced obesity is possibly associated with disruption of PFKFB3 in hematopoietic cells

Laboratory Investigation(2021)10.1038/s41374-020-00523-z

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26 citations

Xin Guo, Hang Xu, Boxiong Jiang, Honggui Li, Yina Wang +9 more

Mast cells in liver disease progression: An update on current studies and implications

Hepatology(2021)10.1002/hep.32121

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22 citations

Lindsey Kennedy, Leonardo Baiocchi, Vik Meadows, Burcin Ekser, Debjyoti Kundu +7 more

Circadian Rhythm and Melatonin in Liver Carcinogenesis: Updates on Current Findings

Critical Reviews™ in Oncogenesis(2021)10.1615/critrevoncog.2021039881

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15 citations

Lixian Chen, Leonardo Baiocchi, Ludovica Ceci, Shannon Glaser, Heather Francis +3 more

Cyclic AMP Signaling in Biliary Proliferation: A Possible Target for Cholangiocarcinoma Treatment?

Cells(2021)10.3390/cells10071692

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12 citations

Ilaria Lenci, Martina Milana, Lindsey Kennedy, Keisaku Sato, Wenjun Zhang +7 more

Current Advances in Basic and Translational Research of Cholangiocarcinoma

Cancers(2021)10.3390/cancers13133307

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11 citations

Leonardo Baiocchi, Lindsey Kennedy, Wenjun Zhang, Burcin Ekser, Shannon Glaser +3 more

Role of stem cell factor and granulocyte colony-stimulating factor in remodeling during liver regeneration

UNC Libraries(2021)10.17615/39cr-da92

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6 citations

Sharon DeMorrow, Yuyan Han, Shannon Glaser, Melanie White, Fanyin Meng +7 more

p16 Vivo‐Morpholino Treatment Attenuates Hepatic Senescence and Non‐Alcoholic Fatty Liver Disease Phenotypes in a Diet‐Induced Rodent Model

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.04186

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0 citations

Heather Francis, Debjyoti Kundu

Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC

Gut(2022)10.1136/gutjnl-2021-326500

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106 citations

Jeremy Wang, Billy Ngo, Vik Meadows, Jason W. Tam, Amba Viswanathan +17 more

Hepatocyte Adenosine Kinase Promotes Excessive Fat Deposition and Liver Inflammation

Gastroenterology(2022)10.1053/j.gastro.2022.09.027

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56 citations

Juan Zheng, Qian Xu, Yongjian Yang, Jing Zhou, Xinlei Guo +13 more

Secretin alleviates biliary and liver injury during late-stage primary biliary cholangitis via restoration of secretory processes

Journal of Hepatology(2022)10.1016/j.jhep.2022.07.034

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47 citations

Guido Carpino, Travis Owen, Ludovica Ceci, Debjyoti Kundu, Vik Meadows +13 more

The Functional Roles of Immune Cells in Primary Liver Cancer

American Journal Of Pathology(2022)10.1016/j.ajpath.2022.02.004

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42 citations

Konstantina Kyritsi, Tianhao Zhou, Ludovica Ceci, Leonardo Baiocchi, Lindsey Kennedy +6 more

Role of ductular reaction and ductular–canalicular junctions in identifying severe primary biliary cholangitis

JHEP Reports(2022)10.1016/j.jhepr.2022.100556

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27 citations

Guido Carpino, Laura Cristoferi, Paolo Onori, Lindsey Kennedy, Heather Francis +15 more

Pathophysiological Roles of Ductular Reaction in Liver Inflammation and Hepatic Fibrogenesis

Cellular and Molecular Gastroenterology and Hepatology(2022)10.1016/j.jcmgh.2022.11.006

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17 citations

Linh Pham, Shannon Glaser, Heather Francis, Gianfranco Alpini, Keisaku Sato

RETRACTED: The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling

Cells(2022)10.3390/cells11091591

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16 citations

Ludovica Ceci, Lindsey Kennedy, Heather Francis, Vik Meadows, Lixian Chen +13 more

Development and Characterization of Human Primary Cholangiocarcinoma Cell Lines

American Journal Of Pathology(2022)10.1016/j.ajpath.2022.05.007

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15 citations

Ali Yenigun, Daiki Soma, Eric Aksu, Kevin Lopez, Yujin Park +12 more

Prolonged Administration of Melatonin Ameliorates Liver Phenotypes in Cholestatic Murine Model

Cellular and Molecular Gastroenterology and Hepatology(2022)10.1016/j.jcmgh.2022.07.007

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13 citations

Lixian Chen, Leonardo Baiocchi, Nan Wu, Lindsey Kennedy, Guido Carpino +15 more

FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2−/− Mouse Model of Primary Sclerosing Cholangitis

Hepatology Communications(2022)10.1002/hep4.1909

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10 citations

Tianhao Zhou, Tori White, Abigail Medford, Lixian Chen, Konstantina Kyritsi +15 more

Indole supplementation ameliorates MCD-induced NASH in mice

The Journal of Nutritional Biochemistry(2022)10.1016/j.jnutbio.2022.109041

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16 citations

Honggui Li, Bangchao Lu, Xinlei Guo, Chia‐Shan Wu, Fen Wang +7 more

Molecular Mechanisms Linking Risk Factors to Cholangiocarcinoma Development

Cancers(2022)10.3390/cancers14061442

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15 citations

Tianhao Zhou, Ilaria Lenci, Vik Meadows, Lindsey Kennedy, Ping Li +11 more

Three-Dimensional Organoids as a Model to Study Nonalcoholic Fatty Liver Disease

Seminars in Liver Disease(2022)10.1055/a-1934-5588

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12 citations

Deepthi Thadasina, Ifeoluwa Bolujo, Abdulkadir Isidan, Arthur A. Cross-Najafi, Kevin Lopez +9 more

Mast cells selectively target large cholangiocytes during biliary injury via H2HR‐mediated cAMP/pERK1/2 signaling

Hepatology Communications(2022)10.1002/hep4.2026

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11 citations

Vik Meadows, Debjyoti Kundu, Konstantina Kyritsi, Travis Owen, Ludovica Ceci +10 more

Healthy peribiliary glands are necessary for successful liver transplantation

Hepatology(2022)10.1002/hep.32382

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3 citations

Debjyoti Kundu, Leonardo Baiocchi, Heather Francis

Macrophage-Specific SCAP Promotes Liver and Adipose Tissue Damage in a Lean NAFLD Model: Lean, Mean, Proinflammatory Machine

Cellular and Molecular Gastroenterology and Hepatology(2022)10.1016/j.jcmgh.2022.04.004

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2 citations

Heather Francis, Gianfranco Alpini, Lindsey Kennedy

What the duct: Imaging ductular reaction spanning the fibrotic areas in primary sclerosing cholangitis (PSC)

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease(2022)10.1016/j.bbadis.2022.166392

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0 citations

Heather Francis, Gianfranco Alpini, Lindsey Kennedy, Travis Owen

Lipocalin‐2 Stimulates Proliferation and a Profibrotic Cholangiocyte Phenotype during Cholestasis

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5479

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0DataRank · unranked

0 citations

Danaleigh Stiles, Tori White, Matthew R. Lopez, Ashleigh Little, J. R. Childs +9 more

Endothelin Receptor-A Inhibition Decreases Ductular Reaction, Liver Fibrosis, and Angiogenesis in a Model of Cholangitis

Cellular and Molecular Gastroenterology and Hepatology(2023)10.1016/j.jcmgh.2023.06.005

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24 citations

Guido Carpino, Lixian Chen, Debjyoti Kundu, Payton G. Wills, Burcin Ekser +6 more

p16 INK4A drives nonalcoholic fatty liver disease phenotypes in high fat diet fed mice through biliary E2F1/FOXO1/IGF-1 signaling

Hepatology(2023)10.1097/hep.0000000000000307

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21 citations

Lindsey Kennedy, Tianhao Zhou, Burcin Ekser, Vik Meadows, Amelia Sybenga +12 more

Growth Hormone Signaling in Liver Diseases: Therapeutic Potentials and Controversies

Seminars in Liver Disease(2023)10.1055/a-2015-1359

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9 citations

Heather Francis, Keisaku Sato, Madisyn Oxley

Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity

Cell & Bioscience(2023)10.1186/s13578-022-00945-w

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7 citations

Nan Wu, Tianhao Zhou, Guido Carpino, Leonardo Baiocchi, Lindsey Kennedy +15 more

Gallstone and Gallbladder Disease: Biliary Tract and Cholangiopathies

Comprehensive physiology(2023)10.1002/cphy.c220028

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9 citations

Yuyan Han, Kelsey Krutsinger, Leonardo Baiocchi, Nan Wu, Debjyoti Kundu +7 more