Stuart A. Lipton

Also affiliated with University of California San Diego

NeuroscienceMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 41 papers. Top paper: “S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson's Disease and Lewy Body Dementia”.

S-Nitrosylation of p62 Inhibits Autophagic Flux to Promote α-Synuclein Secretion and Spread in Parkinson's Disease and Lewy Body Dementia

Journal of Neuroscience(2022)10.1523/jneurosci.1508-21.2022

N/A

2.2DataRank · unranked

53 citations

Nima Dolatabadi, Piotr Cieplak, Maria T. Diaz-Meco, Jorge Moscat, John P. Nolan +3 more

Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation

Immunity(2021)10.1016/j.immuni.2021.05.004

N/A

0.902DataRank · unranked

408 citations

Yuan Liu, A. Nilsson, Raphaella Gatchalian, Timothy R. Crother, Warren G. Tourtellotte +15 more

Autophagy activators normalize aberrant Tau proteostasis and rescue synapses in human familial Alzheimer’s disease iPSC-derived cortical organoids

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.25.661453

N/A

0.241DataRank · unranked

4 citations

Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal +19 more

Control of mammalian brain ageing by the unfolded protein response transcription factor XBP1

Research Square(2020)10.21203/rs.3.rs-83658/v1

N/A

0DataRank · unranked

0 citations

Giovanni Tamburini, Gabriela Martínez, Danilo B. Medinas, Yannis Gerakis, Tim Miedema +19 more

Nr3a-containing NMDA receptors promote neurotransmitter release and spike timing-dependent plasticity

UNC Libraries(2020)10.17615/hwd8-3h24

N/A

0DataRank · unranked

0 citations

Rebekah Corlew, Maile A. Henson, Isabel Pérez‐Otaño, Benjamin D. Philpot, Richard J. Weinberg +6 more

Soluble α-synuclein–antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2025847118

N/A

0DataRank · unranked

135 citations

Kristopher L. Nazor, Yvonne S. Eisele, Titas Grabauskas, Nima Dolatabadi, James Parker +12 more

α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss

Journal of Neuroscience(2021)10.1523/jneurosci.1871-20.2020

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0DataRank · unranked

102 citations

Sara Sanz‐Blasco, Yvonne S. Eisele, Swagata Ghatak, Karthik Bodhinathan, Mohd Waseem Akhtar +6 more

Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration

Free Radical Biology and Medicine(2021)10.1016/j.freeradbiomed.2021.07.002

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0DataRank · unranked

77 citations

Chang-ki Oh, Xu Zhang, Stuart A. Lipton, Tomohiro Nakamura

Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases

International Journal of Molecular Sciences(2021)10.3390/ijms22158196

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0DataRank · unranked

24 citations

Swagata Ghatak, Stuart A. Lipton, Dorit Trudler

TCA cycle metabolic compromise due to an aberrant S-nitrosoproteome in HIV-associated neurocognitive disorder with methamphetamine use

Journal of NeuroVirology(2021)10.1007/s13365-021-00970-4

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0DataRank · unranked

12 citations

Tomohiro Nakamura, Henry Scott, Scott R. McKercher, Abdullah Sultan, Amanda K. Deal +4 more

Potential Therapeutic Use of the Rosemary Diterpene Carnosic Acid for Alzheimer’s Disease, Parkinson’s Disease, and Long-COVID through NRF2 Activation to Counteract the NLRP3 Inflammasome

Antioxidants(2022)10.3390/antiox11010124

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0DataRank · unranked

123 citations

Dorit Trudler, Chang-ki Oh, Stuart A. Lipton, Takumi Satoh

Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging

The EMBO Journal(2022)10.15252/embj.2022111952

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0DataRank · unranked

78 citations

Giovanni Tamburini, Gabriela Martínez, Álvaro O. Ardiles, Danilo B. Medinas, Yannis Gerakis +24 more

Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection

Nature Chemical Biology(2022)10.1038/s41589-022-01149-6

N/A

0DataRank · unranked

35 citations

Tomohiro Nakamura, Nathan Beutler, Xu Zhang, Juan Piña-Crespo, Maria Talantova +24 more

S-Nitrosylation of cathepsin B affects autophagic flux and accumulation of protein aggregates in neurodegenerative disorders

Cell Death and Differentiation(2022)10.1038/s41418-022-01004-0

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0DataRank · unranked

31 citations

Eun‐Jung Cho, Jae-Won Eom, Sang‐Seok Oh, Tomohiro Nakamura, Chang-ki Oh +3 more

Hidden networks of aberrant protein transnitrosylation contribute to synapse loss in Alzheimer's disease

Free Radical Biology and Medicine(2022)10.1016/j.freeradbiomed.2022.10.272

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0DataRank · unranked

11 citations

Stuart A. Lipton

Towards development of disease-modifying therapy for Alzheimer's disease using redox chemical biology pathways

Current Opinion in Pharmacology(2022)10.1016/j.coph.2022.102267

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0DataRank · unranked

6 citations

Stuart A. Lipton

Inhibition of autophagic flux by S-nitrosylation of SQSTM1/p62 promotes neuronal secretion and cell-to-cell transmission of SNCA/α-synuclein in Parkinson disease and Lewy body dementia

Autophagy Reports(2022)10.1080/27694127.2022.2076770

N/A

0DataRank · unranked

7 citations

Tomohiro Nakamura, Stuart A. Lipton, Chang-ki Oh

Detecting Boolean Asymmetric Relationships with a Loop Counting Technique and its Implications for Analyzing Heterogeneity within Gene Expression Datasets

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.04.502792

N/A

0DataRank · unranked

3 citations

Wei Lin, Sergio R. Labra, Stuart A. Lipton, Jeremy A. Elman, Nicholas J. Schork +2 more

Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis

Nature Communications(2023)10.1038/s41467-023-36232-6

N/A

0DataRank · unranked

29 citations

Kengo Nakahara, Akihiro Ito, Yuta Iijima, Ryosuke Nomura, Ashutosh Kumar +25 more

Aberrant protein S-nitrosylation contributes to hyperexcitability-induced synaptic damage in Alzheimer’s disease: Mechanistic insights and potential therapies

Frontiers in Neural Circuits(2023)10.3389/fncir.2023.1099467

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0DataRank · unranked

24 citations

Tomohiro Nakamura, Stuart A. Lipton, Swagata Ghatak

S-Nitrosylation-mediated dysfunction of TCA cycle enzymes in synucleinopathy studied in postmortem human brains and hiPSC-derived neurons

Cell chemical biology(2023)10.1016/j.chembiol.2023.06.018

N/A

0DataRank · unranked

24 citations

Hongmei Yang, Alexander Y. Andreyev, Nima Dolatabadi, Henry Scott, Charlene K Raspur +6 more

S-Nitrosylation of CRTC1 in Alzheimer’s disease impairs CREB-dependent gene expression induced by neuronal activity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.25.554320

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0DataRank · unranked

2 citations

Roman Vlkolinský, Chongyang Wu, Nima Dolatabadi, Henry Scott, Olga Prikhodko +7 more

Reply to: Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection

Nature Chemical Biology(2023)10.1038/s41589-023-01425-z

N/A

0DataRank · unranked

1 citations

Juan Piña-Crespo, Maria Talantova, Lauren N. Carnevale, Charlotte A. Stoneham, Mary K. Lewinski +3 more

Redox regulation, protein S-nitrosylation, and synapse loss in Alzheimer’s and related dementias

Neuron(2024)10.1016/j.neuron.2024.10.013

N/A

0DataRank · unranked

40 citations

Tomohiro Nakamura, Xu Zhang, Stuart A. Lipton, Chang-ki Oh

Metabolic Bypass Rescues Aberrant S‐nitrosylation‐Induced TCA Cycle Inhibition and Synapse Loss in Alzheimer's Disease Human Neurons

Advanced Science(2024)10.1002/advs.202306469

N/A

0DataRank · unranked

25 citations

Hongmei Yang, Paschalis‐Thomas Doulias, Nima Dolatabadi, Xu Zhang, Melissa Luevanos +8 more

Single‐Cell Patch‐Clamp/Proteomics of Human Alzheimer's Disease iPSC‐Derived Excitatory Neurons Versus Isogenic Wild‐Type Controls Suggests Novel Causation and Therapeutic Targets

Advanced Science(2024)10.1002/advs.202400545

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0DataRank · unranked

22 citations

Jolene K. Diedrich, Maria Talantova, Nivedita Bhadra, Henry Scott, Meetal Sharma +5 more

Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids

Molecular Psychiatry(2024)10.1038/s41380-024-02761-9

N/A

0DataRank · unranked

15 citations

Swagata Ghatak, Michael Bula, James Parker, Maria Talantova, Melissa Luevanos +25 more

Enzymatic and non-enzymatic transnitrosylation: “SCAN”ning the SNO-proteome

Molecular Cell(2024)10.1016/j.molcel.2023.12.018

N/A

0DataRank · unranked

8 citations

Stuart A. Lipton, Tomohiro Nakamura

Using in vivo intact structure for system-wide quantitative analysis of changes in proteins

Nature Communications(2024)10.1038/s41467-024-53582-x

N/A

0DataRank · unranked

7 citations

H. S. Kim, Jolene K. Diedrich, Casimir Bamberger, Daniel B. McClatchy, Stuart A. Lipton +2 more

Detecting Boolean Asymmetric Relationships With a Loop Counting Technique and its Implications for Analyzing Heterogeneity Within Gene Expression Datasets

IEEE Transactions on Computational Biology and Bioinformatics(2024)10.1109/tcbb.2024.3487434

N/A

0DataRank · unranked

2 citations

Wei Lin, Sergio R. Labra, Stuart A. Lipton, Jeremy A. Elman, Nicholas J. Schork +2 more

S-Nitrosylation of CRTC1 in Alzheimer’s disease impairs CREB-dependent gene expression induced by neuronal activity

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2418179122

N/A

0DataRank · unranked

12 citations

Roman Vlkolinský, Chongyang Wu, Nima Dolatabadi, Henry Scott, Olga Prikhodko +8 more

diAcCA, a Pro-Drug for Carnosic Acid That Activates the Nrf2 Transcriptional Pathway, Shows Efficacy in the 5xFAD Transgenic Mouse Model of Alzheimer’s Disease

Antioxidants(2025)10.3390/antiox14030293

N/A

0DataRank · unranked

9 citations

Yubo Wang, Lauren N. Carnevale, Parth Patel, Charlene K Raspur, Nancy Tran +6 more

Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice

Journal of Clinical Investigation(2025)10.1172/jci186432

N/A

0DataRank · unranked

6 citations

Julia A. Callender, Joshua E. Mayfield, Daniel B. McClatchy, Daniel Ojeda-Juárez, Mahsa Pourhamzeh +26 more

Novel Therapeutic Approach for Excitatory/Inhibitory Imbalance in Neurodevelopmental and Neurodegenerative Diseases

The Annual Review of Pharmacology and Toxicology(2020)10.1146/annurev-pharmtox-032320-015420

N/A

0DataRank · unranked

87 citations

Maria Talantova, Scott R. McKercher, Stuart A. Lipton, Swagata Ghatak

Redox modulation of the complement cascade contributes to synapse loss in Alzheimer's disease

Neurotherapeutics(2025)10.1016/j.neurot.2025.e00707

N/A

0DataRank · unranked

3 citations

Yubo Wang, Stuart A. Lipton, Chang-ki Oh

Proteome-wide profiling of S-nitrosylated proteins using the SNOTRAP probe and mass spectrometry-based detection

Nature Protocols(2025)10.1038/s41596-025-01282-1

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0DataRank · unranked

3 citations

Haitham Amal, Steven R. Tannenbaum, Stuart A. Lipton, Hongmei Yang

Aberrant S-nitrosylation in the TCA cycle contributes to mitochondrial dysfunction, energy compromise, and synapse loss in neurodegenerative diseases

Neurotherapeutics(2025)10.1016/j.neurot.2025.e00708

N/A

0DataRank · unranked

2 citations

Anamika Sharma, Stuart A. Lipton, Tomohiro Nakamura

Gasotransmitter signaling in the brain: New frontiers for therapeutics

Neurotherapeutics(2025)10.1016/j.neurot.2025.e00784

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0DataRank · unranked

2 citations

Louis J. Ignarro, Stuart A. Lipton, Bindu D. Paul

The transcriptional and cellular landscape of cognitive resilience to Alzheimer’s disease

Frontiers in Molecular Neuroscience(2025)10.3389/fnmol.2025.1665802

N/A

0DataRank · unranked

3 citations

Ravikiran M. Raju, Stuart A. Lipton, Nina Khera

NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models

Molecular Psychiatry(2020)10.1038/s41380-020-0776-7

N/A

0DataRank · unranked

79 citations

Nima Dolatabadi, Richard Gao, Yin Wu, Henry Scott, Dorit Trudler +8 more

Control of mammalian brain aging by the unfolded protein response (UPR)

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.13.039172

N/A

0DataRank · unranked

17 citations

Giovani Tamburini, Gabriela Martínez, Danilo B. Medinas, Yannis Gerakis, Tim Miedema +19 more