🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

William R. Sellers

Broad Institute

ORCID: 0000-0002-3539-9803

Also affiliated with Dana-Farber Cancer Institute

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile
12.7Author DataRank

Indexed papers

5in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Next-generation characterization of the Cancer Cell Line Encyclopedia

Nature(2019)10.1038/s41586-019-1186-3
Top 3%
6.8DataRank
Top 3%3735 citations

Franklin W. Huang, Gregory V. Kryukov, E. Robert McDonald, Jordi Barretina, Ellen T. Gelfand +68 more

Papers

Driven by 17 papers — median percentile 48. Top paper: “M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth”.

M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth

Proceedings of the National Academy of Sciences(2013)10.1073/pnas.1212780110
N/A
7.5DataRank · unranked
161 citations

Christelle Hemmerlin, Stephane Ferretti, Juan Zhang, John S. Gounarides, Hong Yin +6 more

Next-generation characterization of the Cancer Cell Line Encyclopedia

Nature(2019)10.1038/s41586-019-1186-3
Top 3%
6.8DataRank
Top 3%3735 citations

Franklin W. Huang, Gregory V. Kryukov, E. Robert McDonald, Jordi Barretina, Ellen T. Gelfand +68 more

Quantitative Proteomics of the Cancer Cell Line Encyclopedia

Cell(2020)10.1016/j.cell.2019.12.023
Top 3%
5.9DataRank
Top 3%1051 citations

John Szpyt, Mahmoud Ghandi, Christopher M. Rose, E. Robert McDonald, Marian Kalocsay +15 more

EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

Science(2004)10.1126/science.1099314
N/A
1.4DataRank · unranked
9384 citations

Pasi A. Jänne, Jeffrey C. Lee, Sean Tracy, Heidi Greulich, Anthony Philippakis +13 more

The landscape of somatic copy-number alteration across human cancers

Nature(2010)10.1038/nature08822
N/A
1.2DataRank · unranked
4101 citations

Craig H. Mermel, Dale A. Porter, Guo Wei, Soumya Raychaudhuri, Jerry Donovan +61 more

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

Proceedings of the National Academy of Sciences(2007)10.1073/pnas.0710052104
N/A
1.0DataRank · unranked
1085 citations

Gad Getz, Leia Nghiemphu, Jordi Barretina, Teli Hsueh, David Linhart +31 more

Integrated Genome-Wide DNA Copy Number and Expression Analysis Identifies Distinct Mechanisms of Primary Chemoresistance in Ovarian Carcinomas

Clinical Cancer Research(2009)10.1158/1078-0432.ccr-08-1564
N/A
0.858DataRank · unranked
303 citations

Anna deFazio, Rameen Beroukhim, Joshy George, Gad Getz, Richard Tothill +26 more

Discovery of a First-in-Class Inhibitor of the PRMT5–Substrate Adaptor Interaction

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00507
N/A
0.598DataRank · unranked
53 citations

Brian J. McMillan, Matthew J. Ranaghan, Jamie A. Moroco, Merissa Brousseau, Zachary Mullin-Bernstein +18 more

Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer

Cancer Discovery(2025)10.1158/2159-8290.cd-24-1378
N/A
0.292DataRank · unranked
6 citations

Devishi Kesar, Yenarae Lee, Amy Goodale, Sudeepa Syamala, Shweta Kukreja +11 more

Substrate adaptors are flexible tethering modules that enhance substrate methylation by the arginine methyltransferase PRMT5

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108165
N/A
0.208DataRank · unranked
3 citations

Moritz Hunkeler, Kathleen M. Mulvaney, William R. Sellers, Eric S. Fischer, Cyrus Y. Jin

Highly multiplexed quantitative phosphosite assay for biology and preclinical studies

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.08.415281
N/A
0.122DataRank · unranked
1 citations

E. Robert McDonald, Randy Melanson, Dale Porter, Filip Mundt, Karsten Krug +21 more

Distinct CDK6 complexes determine tumor cell response to CDK4/6 inhibitors and degraders

Nature Cancer(2021)10.1038/s43018-021-00174-z
N/A
0DataRank · unranked
73 citations

Xiaobao Yang, Yan Xiong, Ruitong Li, Takahiro Ito, Tamer A. Ahmed +14 more

A Kinetic Scout Approach Accelerates Targeted Protein Degrader Development

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.17.612508
N/A
0DataRank · unranked
1 citations

Gillian E. Gadbois, Hai‐Tsang Huang, Jiewei Jiang, Logan H. Sigua, Emily R. Smith +9 more

Data from Homozygous Deletions and Chromosome Amplifications in Human Lung Carcinomas Revealed by Single Nucleotide Polymorphism Array Analysis

(2023)10.1158/0008-5472.c.6493908.v1
Top 100%
0DataRank
Top 100%0 citations

Barbara A. Weir, Thomas LaFramboise, Ming Lin, Rameen Beroukhim, Levi A. Garraway +15 more

Data from TMPRSS2:ERG Fusion-Associated Deletions Provide Insight into the Heterogeneity of Prostate Cancer

(2023)10.1158/0008-5472.c.6494447
N/A
0DataRank · unranked
0 citations

Francesca Demichelis, Rameen Beroukhim, Folke Schmidt, Juan‐Miguel Mosquera, Sunita R. Setlur +13 more

Data from TMPRSS2:ERG Fusion-Associated Deletions Provide Insight into the Heterogeneity of Prostate Cancer

(2023)10.1158/0008-5472.c.6494447.v1
N/A
0DataRank · unranked
0 citations

Francesca Demichelis, Rameen Beroukhim, Folke Schmidt, Juan‐Miguel Mosquera, Sunita R. Setlur +13 more

Data from Homozygous Deletions and Chromosome Amplifications in Human Lung Carcinomas Revealed by Single Nucleotide Polymorphism Array Analysis

(2023)10.1158/0008-5472.c.6493908
Top 100%
0DataRank
Top 100%0 citations

Barbara A. Weir, Thomas LaFramboise, Ming Lin, Rameen Beroukhim, Levi A. Garraway +15 more