Bruce Beutler

Also affiliated with The University of Texas Southwestern Medical Center

Immunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 46 papers. Top paper: “Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene”.

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Science(1998)10.1126/science.282.5396.2085

N/A

1.3DataRank · unranked

7593 citations

Xiaolong He, Irina Smirnova, Mu-Ya Liu, Christophe Van Huffel, Xin Du +12 more

Sulfatides are endogenous ligands for the TLR4–MD-2 complex

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2105316118

N/A

0.633DataRank · unranked

67 citations

Muhammad Athamna, Ying Wang, Junmei Wang, Marina A. Freudenberg, Tao Yue +6 more

Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2000703117

N/A

0.626DataRank · unranked

15 citations

Lijing Su, Yi Yang, Evan Nair‐Gill, Miao Tang, Priscilla Anderton +9 more

Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis

Communications Biology(2023)10.1038/s42003-023-04870-7

N/A

0.524DataRank · unranked

10 citations

Bogale Aredo, Yeshumenesh Zegeye, Cynthia X. Zhao, Miao Tang, Xiaohong Li +8 more

Essential requirement for nicastrin in marginal zone and B-1 B cell development

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1916645117

N/A

0.457DataRank · unranked

20 citations

Jonghee Han, Panayotis C. Theodoropoulos, Xue Zhong, Jianhui Wang, Dawson Medler +8 more

OVOL2 sustains postnatal thymic epithelial cell identity

Nature Communications(2023)10.1038/s41467-023-43456-z

N/A

0.345DataRank · unranked

7 citations

Nagesh Peddada, Jianhui Wang, James J. Moresco, Xiaowei Zhan, John M. Shelton +7 more

Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice

Journal of Bone and Mineral Research(2020)10.1002/jbmr.4323

N/A

0DataRank · unranked

11 citations

Kristin Denton, Jamie L. Russell, Julia Kozlitina, Carlos R. Ferreira, Amy Feldman Lewanda +18 more

Tissue-specific disruption of Kbtbd2 uncovers adipocyte-intrinsic and -extrinsic features of the teeny lipodystrophy syndrome

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2000118117

N/A

0DataRank · unranked

8 citations

T. F. Gallagher, Philipp E. Scherer, Bruce Beutler, Zhao Zhang

Mechanism of negative regulation of NF-κB by N4BP1

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.21.349357

N/A

0DataRank · unranked

1 citations

Lei Sun, Ying Wang, Aijie Liu, Xiaoming Zhan, Xiaohong Li +8 more

Candidate Explorer: a tool for discovery, evaluation, and display of mutations causing significant immune phenotypes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.07.371914

N/A

0DataRank · unranked

0 citations

Stephen Lyon, Chun Hui Bu, Sara Hildebrand, Jin Huk Choi, Xue Zhong +42 more

SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell–mediated immunity

Science(2021)10.1126/science.aba4220

N/A

0DataRank · unranked

82 citations

Xiaoming Zhan, Duanwu Zhang, Ruchi Jain, Kuan-Wen Wang, Jin Huk Choi +11 more

N4BP1 negatively regulates NF-κB by binding and inhibiting NEMO oligomerization

Nature Communications(2021)10.1038/s41467-021-21711-5

N/A

0DataRank · unranked

47 citations

Lei Sun, Ying Wang, Aijie Liu, Xiaoming Zhan, Xiaohong Li +8 more

Calcium flux control by Pacs1‐Wdr37 promotes lymphocyte quiescence and lymphoproliferative diseases

The EMBO Journal(2021)10.15252/embj.2020104888

N/A

0DataRank · unranked

33 citations

Massimo Bonora, Xue Zhong, Aijie Liu, Amber Miranda, Nathan Stewart +6 more

Quantification of early learning and movement sub-structure predictive of motor performance

Scientific Reports(2021)10.1038/s41598-021-93944-9

N/A

0DataRank · unranked

24 citations

William Scudder, Gauri Kathote, Qian Ma, Gustavo Angulo, Aksharkumar Dobariya +4 more

Thousands of induced germline mutations affecting immune cells identified by automated meiotic mapping coupled with machine learning

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2106786118

N/A

0DataRank · unranked

17 citations

Stephen Lyon, Chun Hui Bu, Sara Hildebrand, Jin Huk Choi, Xue Zhong +50 more

Saturation mutagenesis defines novel mouse models of severe spine deformity

Disease Models & Mechanisms(2021)10.1242/dmm.048901

N/A

0DataRank · unranked

6 citations

Kristin Denton, Hao Yu, Kandamurugu Manickam, Shannon Garner, Jamie L. Russell +8 more

De novo germline mutation in the Dual Specificity Phosphatase 10 gene accelerates autoimmune diabetes in Non-Obese Diabetic (NOD) mice

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2020.12.30.424747

N/A

0DataRank · unranked

0 citations

Sophie Candon, Sara Hildebrand, Cindy Marquet, Fabrice Valette, Coralie Pecquet +16 more

The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid–sensing TLRs and ligands to endolysosomes

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2200544119

N/A

0DataRank · unranked

41 citations

Rosana González‐Quintial, Roberto Baccalà, William B. Kiosses, John R. Teijaro, Christopher G. Parker +5 more

Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity

Nature Communications(2022)10.1038/s41467-022-31812-4

N/A

0DataRank · unranked

17 citations

Yu Xun, Shunxing Rong, Lijuan Yan, Jeffrey A. SoRelle, Xiaohong Li +6 more

Next-Generation Diprovocims with Potent Human and Murine TLR1/TLR2 Agonist Activity That Activate the Innate and Adaptive Immune Response

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00419

N/A

0DataRank · unranked

13 citations

Jamie L. Russell, Yuto Mifune, Ying Wang, Hexin Shi, Eva Marie Y. Moresco +4 more

Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis

Cell Metabolism(2022)10.1016/j.cmet.2022.09.018

N/A

0DataRank · unranked

16 citations

Yiao Jiang, Lijing Su, Sara Ludwig, Xuechun Zhang, Miao Tang +19 more

RNPS1 inhibits excessive tumor necrosis factor/tumor necrosis factor receptor signaling to support hematopoiesis in mice

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2200128119

N/A

0DataRank · unranked

12 citations

Jin Huk Choi, Sara Hildebrand, Sara Ludwig, Jianhui Wang, Evan Nair‐Gill +14 more

Modulation of autoimmune diabetes by N-ethyl-N-nitrosourea- induced mutations in non-obese diabetic mice

Disease Models & Mechanisms(2022)10.1242/dmm.049484

N/A

0DataRank · unranked

3 citations

Cindy Marquet, Fabrice Valette, Lindsay Scott, Jiexia Quan, Chun Hui Bu +5 more

Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation

Nature Communications(2023)10.1038/s41467-023-39398-1

N/A

0DataRank · unranked

13 citations

William McAlpine, Aaron M. Fond, Evan Nair‐Gill, Jin Huk Choi, Elisabeth Nyström +13 more

Essential role of MFSD1-GLMP-GIMAP5 in lymphocyte survival and liver homeostasis

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2314429120

N/A

0DataRank · unranked

11 citations

James J. Moresco, Jolene K. Diedrich, Antônio F. M. Pinto, Jeffrey A. SoRelle, Jianhui Wang +8 more

Essential requirement for IER3IP1 in B cell development

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2312810120

N/A

0DataRank · unranked

10 citations

James J. Moresco, Katie Keller, Danielle Renee Lazaro, Claire Ely, Eva Marie Y. Moresco +3 more

The dual lipid desaturase/hydroxylase DEGS2 controls phytoceramide levels necessary to counter intestinal inflammation

Disease Models & Mechanisms(2023)10.1242/dmm.050043

N/A

0DataRank · unranked

5 citations

Aaron Fond, Xiaohong Li, Miao Tang, Xiaoming Zhan, Ruth Gordillo +4 more

Dynamic molecular architecture and substrate recruitment of cullin3–RING E3 ligase CRL3KBTBD2

Nature Structural & Molecular Biology(2024)10.1038/s41594-023-01182-6

N/A

0DataRank · unranked

22 citations

Zhao Zhang, Qiyu Mao, Xiang Zhang, Aihua Hao, Yu Xun +11 more

Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.08.570738

N/A

0DataRank · unranked

0 citations

Luming Chen, Aijie Liu, Jianhui Wang, Subarna Ghosh, Xue Zhong +4 more

Viable mutations of mouse midnolin suppress B cell malignancies

The Journal of Experimental Medicine(2024)10.1084/jem.20232132

N/A

0DataRank · unranked

15 citations

Nagesh Peddada, James J. Moresco, Jianhui Wang, Yiao Jiang, Jonathan J. Rios +4 more

E3 ubiquitin ligase Herc3 deficiency leads to accumulation of subretinal microglia and retinal neurodegeneration

Scientific Reports(2024)10.1038/s41598-024-53731-8

N/A

0DataRank · unranked

9 citations

Bogale Aredo, Seher Yüksel, Dogan Can Kirman, Ashwani Kumar, Bo Chen +14 more

Suppression of melanoma by mice lacking MHC-II: Mechanisms and implications for cancer immunotherapy

The Journal of Experimental Medicine(2024)10.1084/jem.20240797

N/A

0DataRank · unranked

8 citations

Dawson Medler, Jianhui Wang, Rachel Browning, Aijie Liu, Sara Schneider +10 more

Disruption of the ZFP574–THAP12 complex suppresses B cell malignancies in mice

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2409232121

N/A

0DataRank · unranked

5 citations

James J. Moresco, Jeffrey A. SoRelle, Ran Song, Yiao Jiang, Mylinh T. Nguyen +6 more

Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity

EMBO Reports(2024)10.1038/s44319-024-00191-w

N/A

0DataRank · unranked

4 citations

Luming Chen, Aijie Liu, Jianhui Wang, Subarna Ghosh, Xue Zhong +4 more

Nonredundant Role of Leishmanolysin-Like (Lmln) Zinc-Metallopeptidase in Retinal Homeostasis

American Journal of Ophthalmology(2024)10.1016/j.ajo.2024.08.016

N/A

0DataRank · unranked

1 citations

Dogan Can Kirman, Gizem Ulker-Yilmazer, Bogale Aredo, Sangita Shrestha, Emily Turpin +7 more

Deep Learning-Based Automated Measurement of Murine Bone Length in Radiographs

Bioengineering(2024)10.3390/bioengineering11070670

N/A

0DataRank · unranked

1 citations

Kristin Denton, Kevin W. Jin, Peiran Quan, Zhuoyu Wen, Julia Kozlitina +9 more

Structural insights into the ubiquitin-independent midnolin-proteasome pathway

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2505345122

N/A

0DataRank · unranked

13 citations

Xue Zhong, Yan Yin, Danielle Renee Lazaro, Jianhui Wang, Stephen Lyon +5 more

Structural insights into GM4951 as a lipid droplet GTPase regulating hepatic lipid metabolism

Nature Communications(2025)10.1038/s41467-025-66253-2

N/A

0DataRank · unranked

1 citations

Yiao Jiang, Rahul Kumar Jha, Eva Marie Y. Moresco, Himanshu Joshi, Zhao Zhang +2 more

The Rab32-LRMDA-Retriever Complex is a Key Regulator of Intestinal Immune Homeostasis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.16.665158

N/A

0DataRank · unranked

1 citations

Chigozie Ngoka, Amika Singla, Daniel A. Kramer, Alka Diwaker, Daniel J. Boesch +8 more

A hypomorphic Mpi mutation unlocks an in vivo tool for studying global N-glycosylation deficiency

JCI Insight(2025)10.1172/jci.insight.180752

N/A

0DataRank · unranked

0 citations

Steve Meregini, Zhao Zhang, Avishek Roy, Tandav Argula, James Mitchell +9 more

The Structural Basis for Pacs1-Wdr37 Complex Assembly and Stability

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.05.686565

N/A

0DataRank · unranked

0 citations

Magdalena Grzemska, Xiong Pi, Luming Chen, Michael G. Turner, Nagesh Peddada +6 more

Tumour predisposition and cancer syndromes as models to study gene–environment interactions

Nature reviews. Cancer(2020)10.1038/s41568-020-0265-y

N/A

0DataRank · unranked

194 citations

Sarah T. Arron, Bruce Beutler, Angela Bononi, Webster K. Cavenee, James E. Cleaver +18 more

Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development

The Journal of Experimental Medicine(2020)10.1084/jem.20190006

N/A

0DataRank · unranked

21 citations

Xue Zhong, Zhao Zhang, Lijing Su, William McAlpine, Takuma Misawa +10 more

Forward genetic analysis using OCT screening identifies Sfxn3 mutations leading to progressive outer retinal degeneration in mice

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1921224117

N/A

0DataRank · unranked

21 citations

Bogale Aredo, Yi Ding, Xin Zhong, Yuanfei Zhu, Cynthia X. Zhao +13 more

Dominant atopy risk mutations identified by mouse forward genetic analysis

Allergy(2020)10.1111/all.14564

N/A

0DataRank · unranked

14 citations

Zhe Chen, Jianhui Wang, Tao Yue, Jin Huk Choi, Kuan-Wen Wang +16 more

Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation

Science Immunology(2020)10.1126/sciimmunol.aaz0085

N/A

0DataRank · unranked

22 citations

Jeffrey A. SoRelle, Jin Huk Choi, Tao Yue, Kuan-Wen Wang, William McAlpine +20 more