J. Brent Richards

Also affiliated with King's College London, Jewish General Hospital, McGill University, University of Lausanne

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

9.0Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Nature Communications(2015)10.1038/ncomms9111

Top 3%

6.7DataRank

Top 3%386 citations

Bryan Howie, Shane McCarthy, Yasin Memari, Klaudia Walter, Josine L. Min +234 more

Papers

Driven by 67 papers — median percentile 90. Top paper: “Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration”.

Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration

BMJ(2021)10.1136/bmj.n2233

N/A

12.0DataRank · unranked

1710 citations

Rebecca Richmond, Benjamin Woolf, Neil M. Davies, Sonja A. Swanson, Tyler J. VanderWeele +10 more

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Nature Communications(2015)10.1038/ncomms9111

Top 3%

6.7DataRank

Top 3%386 citations

Bryan Howie, Shane McCarthy, Yasin Memari, Klaudia Walter, Josine L. Min +234 more

Performance of Genotype Imputation for Low Frequency and Rare Variants from the 1000 Genomes

PLOS ONE(2015)10.1371/journal.pone.0116487

N/A

2.9DataRank · unranked

70 citations

Jing-Jing Rong, Ming Liu, Fang Han, Xing-Wei Zhang, J. Brent Richards +2 more

Imputation of Variants from the 1000 Genomes Project Modestly Improves Known Associations and Can Identify Low-frequency Variant - Phenotype Associations Undetected by HapMap Based Imputation

PLoS ONE(2013)10.1371/journal.pone.0064343

N/A

2.9DataRank · unranked

75 citations

John R. B. Perry, Toshiko Tanaka, Dena G. Hernandez, Hou-Feng Zheng, David Melzer +10 more

Genetic Determinants of Antibody-Mediated Immune Responses to Infectious Diseases Agents: A Genome-Wide and HLA Association Study

Open Forum Infectious Diseases(2020)10.1093/ofid/ofaa450

Top 10%

2.1DataRank

Top 10%129 citations

Devin Kreuzer, Tomoko Nakanishi, Adil Harroud, Vincenzo Forgetta, J. Brent Richards +1 more

The relative contributions of obesity, vitamin D, leptin, and adiponectin to multiple sclerosis risk: A Mendelian randomization mediation analysis

Multiple Sclerosis Journal(2021)10.1177/1352458521995484

N/A

1.5DataRank · unranked

50 citations

Despoina Manousaki, Guillaume Butler‐Laporte, Ruth E. Mitchell, George Davey Smith, J. Brent Richards +2 more

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus

Journal of Medical Genetics(2013)10.1136/jmedgenet-2013-102064

N/A

1.4DataRank · unranked

38 citations

Yi-Hsiang Hsu, Unnur Styrkarsdottir, Bert H Eussen, Annelies de Klein, Marjolein J. Peters +81 more

Sex Differences in the Risk of Coronary Heart Disease Associated With Type 2 Diabetes: A Mendelian Randomization Analysis

Diabetes Care(2020)10.2337/dc20-1137

N/A

1.3DataRank · unranked

33 citations

Michael V. Holmes, J. Brent Richards, Tom Palmer, Vincenzo Forgetta, Cecilia M. Lindgren +10 more

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

Nature Genetics(2009)10.1038/ng.446

N/A

0.984DataRank · unranked

703 citations

Fernando Rivadeneira, Unnur Styrkársdóttir, Karol Estrada, Bjarni V. Halldórsson, J. Brent Richards +33 more

Dehydration is associated with production of organic osmolytes and predicts physical long-term symptoms after COVID-19: a multicenter cohort study

Critical Care(2022)10.1186/s13054-022-04203-w

N/A

0.581DataRank · unranked

18 citations

Miklós Lipcsey, David Morrison, Tomoko Nakanishi, Guillaume Butler‐Laporte, Yiheng Chen +12 more

Twenty loci associated with bone mineral density identified by large-scale meta-analysis of genome-wide association datasets

Bone(2009)10.1016/j.bone.2009.03.085

N/A

0.535DataRank · unranked

9 citations

Unnur Styrkarsdottir, Bjarni V. Halldorsson, Y. Hsu, Audrey Y. Chu, Y.A. Aulchenko +51 more

Strengthening the reporting of observational studies in epidemiology using Mendelian randomization (STROBE-MR): a Korean translation of explanation and elaboration

Ewha Medical Journal(2025)10.12771/emj.2025.00934

Top 70%

0.165DataRank

Top 70%2 citations

Rebecca Richmond, Benjamin Woolf, Neil M. Davies, Sonja A. Swanson, Tyler J. VanderWeele +10 more

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

Nature Communications(2021)10.1038/s41467-021-22517-1

N/A

0DataRank · unranked

125 citations

John P. Kemp, John G. Logan, Elena J. Ghirardello, C. Marcelo Sergio, Michael R.G. Dack +32 more

Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality

Journal of Clinical Investigation(2021)10.1172/jci152386

N/A

0DataRank · unranked

124 citations

Sara Pigazzini, Frauke Degenhardt, Mattia Cordioli, Guillaume Butler‐Laporte, Douglas Maya-Miles +42 more

Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study

PLoS Medicine(2021)10.1371/journal.pmed.1003605

N/A

0DataRank · unranked

123 citations

Tomoko Nakanishi, Vincent Mooser, David Morrison, Tala Abdullah, Olumide Adeleye +11 more

Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality

Science Advances(2021)10.1126/sciadv.abj5629

N/A

0DataRank · unranked

54 citations

Sai Priya Anand, Pierre Gantner, Alina Dyachenko, Gaël Moquin‐Beaudry, Nathalie Brassard +38 more

RSPO3 is important for trabecular bone and fracture risk in mice and humans

Nature Communications(2021)10.1038/s41467-021-25124-2

N/A

0DataRank · unranked

40 citations

Petra Henning, Maha El Shahawy, Maria Nethander, Thomas Levin Andersen, Charlotte Ejersted +16 more

A Polygenic Risk Score to Predict Future Adult Short Stature Among Children

The Journal of Clinical Endocrinology & Metabolism(2021)10.1210/clinem/dgab215

N/A

0DataRank · unranked

30 citations

Vincenzo Forgetta, Haoyu Wu, John R. B. Perry, Ken K. Ong, Celia M.T. Greenwood +4 more

Health Effects of Calcium: Evidence From Mendelian Randomization Studies

JBMR Plus(2021)10.1002/jbm4.10542

N/A

0DataRank · unranked

20 citations

Vincenzo Forgetta, J. Brent Richards, Sirui Zhou, Yiheng Chen

Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality

medRxiv(2021)10.1101/2021.03.07.21252875

N/A

0DataRank · unranked

29 citations

Sara Pigazzini, Frauke Degenhardt, Mattia Cordioli, Guillaume Butler‐Laporte, Douglas Maya‐Miles +44 more

Alternative splicing of OAS1 alters the risk for severe COVID-19

medRxiv(2021)10.1101/2021.03.20.21254005

N/A

0DataRank · unranked

17 citations

Guillaume Butler‐Laporte, Atlas Khan, Theodore G. Drivas, Gina M. Peloso, Tomoko Nakanishi +5 more

Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality

medRxiv(2021)10.1101/2021.03.18.21253907

N/A

0DataRank · unranked

12 citations

Sai Priya Anand, Pierre Gantner, Gaël Moquin‐Beaudry, Alina Dyachenko, Nathalie Brassard +37 more

Circulating proteins to predict adverse COVID-19 outcomes

medRxiv(2021)10.1101/2021.10.04.21264015

N/A

0DataRank · unranked

4 citations

Sirui Zhou, Edgar Gonzalez‐Kozlova, Guillaume Butler‐Laporte, Elsa Brunet‐Ratnasingham, Tomoko Nakanishi +62 more

Multi-ancestry fine mapping implicates OAS1 splicing in risk of severe COVID-19

Nature Genetics(2022)10.1038/s41588-021-00996-8

N/A

0DataRank · unranked

129 citations

Guillaume Butler‐Laporte, Atlas Khan, Erola Pairo-Castineira, Theodore G. Drivas, Gina M. Peloso +9 more

Polygenic risk score as a possible tool for identifying familial monogenic causes of complex diseases

Genetics in Medicine(2022)10.1016/j.gim.2022.03.022

N/A

0DataRank · unranked

32 citations

Vincenzo Forgetta, J. Brent Richards, Celia M.T. Greenwood, Tianyuan Lu

Capturing additional genetic risk from family history for improved polygenic risk prediction

Communications Biology(2022)10.1038/s42003-022-03532-4

N/A

0DataRank · unranked

18 citations

Vincenzo Forgetta, J. Brent Richards, Celia M.T. Greenwood, Tianyuan Lu

Circulating Isovalerylcarnitine and Lung Cancer Risk: Evidence from Mendelian Randomization and Prediagnostic Blood Measurements

Cancer Epidemiology Biomarkers & Prevention(2022)10.1158/1055-9965.epi-21-1033

N/A

0DataRank · unranked

14 citations

Agustin Cerani, Florence Guida, Sirui Zhou, Antonio Agudo, Krasimira Aleksandrova +28 more

Causal associations between body fat accumulation and COVID-19 severity: A Mendelian randomization study

Frontiers in Endocrinology(2022)10.3389/fendo.2022.899625

N/A

0DataRank · unranked

12 citations

Daisuke Tanaka, Hiroto Minamino, Tianyuan Lu, Guillaume Butler‐Laporte, Takaaki Murakami +4 more

Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity

medRxiv(2022)10.1101/2022.06.06.22275997

N/A

0DataRank · unranked

6 citations

Guillaume Butler‐Laporte, Tianyuan Lu, Julian Willett, Chen‐Yang Su, Tomoko Nakanishi +26 more

Genetic determinants of polygenic prediction accuracy within a population

Research Square(2022)10.21203/rs.3.rs-1157621/v1

N/A

0DataRank · unranked

4 citations

Vincenzo Forgetta, J. Brent Richards, Celia M.T. Greenwood, Tianyuan Lu

Capturing additional genetic risk from family history for improved polygenic risk prediction

medRxiv(2022)10.1101/2022.01.06.22268853

N/A

0DataRank · unranked

3 citations

Vincenzo Forgetta, J. Brent Richards, Celia M.T. Greenwood, Tianyuan Lu

Causal associations between body fat accumulation and COVID-19 severity: A Mendelian randomization study

medRxiv(2022)10.1101/2022.01.20.22269593

N/A

0DataRank · unranked

1 citations

Daisuke Tanaka, Hiroto Minamino, Takaaki Murakami, Yoshihito Fujita, J. Brent Richards +2 more

Vitamin D and the preclinical Alzheimer cognitive composite cognition (PACC) score: a two-sample mendelian randomization study

medRxiv(2022)10.1101/2022.11.23.22282674

N/A

0DataRank · unranked

0 citations

Satoshi Yoshiji, Tianyuan Lu, Guillaume Butler‐Laporte, Sirui Zhou, J. Brent Richards +1 more

Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases

Nature Genetics(2023)10.1038/s41588-022-01270-1

N/A

0DataRank · unranked

989 citations

Tianyuan Lu, U. Pettersson, Isobel D. Stewart, Guillaume Butler‐Laporte, Tomoko Nakanishi +14 more

Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity

Nature Metabolism(2023)10.1038/s42255-023-00742-w

N/A

0DataRank · unranked

117 citations

Guillaume Butler‐Laporte, Tianyuan Lu, Julian Willett, Chen‐Yang Su, Tomoko Nakanishi +26 more

Integrating genetics and metabolomics from multi-ethnic and multi-fluid data reveals putative mechanisms for age-related macular degeneration

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.101085

N/A

0DataRank · unranked

41 citations

Inês Laíns, Jun Li, Jinglun Li, Yiheng Chen, Bing Yu +30 more

Alternative splicing in lung influences COVID-19 severity and respiratory diseases

Nature Communications(2023)10.1038/s41467-023-41912-4

N/A

0DataRank · unranked

34 citations

Julian Willett, Yossi Farjoun, Richard J. Allen, Beatriz Guillén‐Guío, Darin Adra +3 more

HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases

Communications Biology(2023)10.1038/s42003-023-05496-5

N/A

0DataRank · unranked

33 citations

Joseph Farjoun, Tomoko Nakanishi, Tianyuan Lu, Erik Abner, Yiheng Chen +17 more

Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis

Nature Genetics(2023)10.1038/s41588-023-01444-5

N/A

0DataRank · unranked

27 citations

Olukayode Sosina, Jonas Bovijn, Lætitia Laurent, Vasundhara Sharma, Parsa Akbari +24 more

Proteomic characterization of acute kidney injury in patients hospitalized with SARS-CoV2 infection

Communications Medicine(2023)10.1038/s43856-023-00307-8

N/A

0DataRank · unranked

20 citations

Pushkala Jayaraman, Chen‐Yang Su, Sirui Zhou, Steven Chen, Ryan C. Thompson +38 more

Circulating proteins to predict COVID-19 severity

Scientific Reports(2023)10.1038/s41598-023-31850-y

N/A

0DataRank · unranked

19 citations

Sirui Zhou, Edgar Gonzalez‐Kozlova, Guillaume Butler‐Laporte, Elsa Brunet‐Ratnasingham, Tomoko Nakanishi +61 more

Colocalization of expression transcripts with COVID-19 outcomes is rare across cell states, cell types and organs

Human Genetics(2023)10.1007/s00439-023-02590-w

N/A

0DataRank · unranked

5 citations

Tianyuan Lu, Tomoko Nakanishi, Satoshi Yoshiji, Guillaume Butler‐Laporte, Sirui Zhou +3 more

COL6A3-derived endotrophin mediates the effect of obesity on coronary artery disease: an integrative proteogenomics analysis

medRxiv(2023)10.1101/2023.04.19.23288706

N/A

0DataRank · unranked

5 citations

Tianyuan Lu, Guillaume Butler‐Laporte, Julia Carrasco-Zanini, Yiheng Chen, Kevin Y. H. Liang +18 more

Targeting hepatitis B vaccine escape using immunogenetics in Bangladeshi infants

medRxiv(2023)10.1101/2023.06.26.23291885

N/A

0DataRank · unranked

5 citations

Kathryn Auckland, Zannatun Noor, Mamun Kabir, Masud Alam, Tommy Carstensen +23 more

HLA allele-calling using whole-exome sequencing identifies 129 novel associations in 11 autoimmune diseases: a multi-ancestry analysis in the UK Biobank

medRxiv(2023)10.1101/2023.01.15.23284570

N/A

0DataRank · unranked

1 citations

Yossi Farjoun, Tomoko Nakanishi, Tianyuan Lu, Erik Abner, Yiheng Chen +17 more

Colocalization of expression transcripts with COVID-19 outcomes is rare across cell states, cell types and organs

medRxiv(2023)10.1101/2023.05.29.23290694

N/A

0DataRank · unranked

0 citations

Tianyuan Lu, Tomoko Nakanishi, Satoshi Yoshiji, Guillaume Butler‐Laporte, Sirui Zhou +3 more

Aquaporin 3 modulates the risk of death conferred by dehydration in COVID-19

Research Square(2023)10.21203/rs.3.rs-3011474/v1

N/A

0DataRank · unranked

0 citations

Guillaume Butler‐Laporte, Satoshi Yoshiji, Tianyuan Lu, Dave Morrison, Tomoko Nakanishi +9 more

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

Nature Communications(2024)10.1038/s41467-024-44701-9

N/A

0DataRank · unranked

74 citations

Inga Steinbrenner, Yong Li, Melissa Bujnis, Tatsuhiko Naito, Eirini Marouli +95 more

Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity

Nature Communications(2024)10.1038/s41467-024-48556-y

N/A

0DataRank · unranked

19 citations

Sacha Morin, Haley E. Randolph, Marjorie Labrecque, Justin Bélair, Raphaël Lima-Barbosa +42 more

A plasma protein-based risk score to predict hip fractures

Nature Aging(2024)10.1038/s43587-024-00639-7

N/A

0DataRank · unranked

14 citations

Maria Nethander, Howard A Fink, Anna E. Törnqvist, Diana Jalal, Petra Bůžková +24 more

The performance of AlphaMissense to identify genes influencing disease

Human Genetics and Genomics Advances(2024)10.1016/j.xhgg.2024.100344

N/A

0DataRank · unranked

3 citations

Guillaume Butler‐Laporte, Kevin Y. H. Liang, Yann Ilboudo, Summaira Yasmeen, Takayoshi Sasako +4 more

The performance of AlphaMissense to identify genes causing disease

medRxiv(2024)10.1101/2024.03.05.24303647

N/A

0DataRank · unranked

1 citations

Guillaume Butler‐Laporte, Kevin Y. H. Liang, Yann Ilboudo, Summaira Yasmeen, Takayoshi Sasako +4 more

Integrative proteogenomic analysis identifies COL6A3-derived endotrophin as a mediator of the effect of obesity on coronary artery disease

Nature Genetics(2025)10.1038/s41588-024-02052-7

N/A

0DataRank · unranked

30 citations

Tianyuan Lu, Guillaume Butler‐Laporte, Julia Carrasco-Zanini, Chen‐Yang Su, Yiheng Chen +24 more

Caution when using network partners for target identification in drug discovery

Human Genetics and Genomics Advances(2025)10.1016/j.xhgg.2025.100409

N/A

0DataRank · unranked

4 citations

Yiheng Chen, Yann Ilboudo, Kevin Y. H. Liang, Guillaume Butler‐Laporte, J. Brent Richards +1 more

A flexible pipeline for reproducible exome-wide rare variant gene-trait associations

medRxiv(2025)10.1101/2025.06.26.25330270

N/A

0DataRank · unranked

0 citations

Ethan Kreuzer, Yann Ilboudo, Yiheng Chen, J. Brent Richards, Guillaume Butler‐Laporte +1 more

Differential Circulating Proteomic Responses Associated with Ancestry during Severe COVID-19 Infection

Journal of Proteome Research(2025)10.1021/acs.jproteome.4c00956

N/A

0DataRank · unranked

0 citations

Yann Ilboudo, Tianyuan Lu, Guillaume Butler‐Laporte, Tomoko Nakanishi, David Morrison +4 more

A systematic evaluation of 151 candidate genes for their association with osteoporosis and osteoporotic fracture in a meta-analysis of genome-wide association data

Bone(2009)10.1016/j.bone.2009.03.068

N/A

0DataRank · unranked

0 citations

Thomas Quertermous, Unnur Styrkarsdottir, Bjarni V. Halldorsson, Y. Hsu, B. Mullins +47 more

Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study

PLoS Medicine(2020)10.1371/journal.pmed.1003152

N/A

0DataRank · unranked

74 citations

Julyan Keller‐Baruch, Marie Forest, Audrey Durand, Sahir Bhatnagar, John P. Kemp +21 more

Whole-exome sequencing identifies rare variants in STAB2 associated with venous thromboembolic disease

Blood(2020)10.1182/blood.2019004161

N/A

0DataRank · unranked

59 citations

Ayse Bilge Ozel, Matthew Halvorsen, Paula M. Jacobi, Krista Golden, Mary Underwood +11 more

A catalog of associations between rare coding variants and COVID-19 outcomes

medRxiv(2020)10.1101/2020.10.28.20221804

N/A

0DataRank · unranked

31 citations

Julie Horowitz, Nilanjana Banerjee, Rouel Lanche, Anthony Marcketta, Evan K. Maxwell +75 more

Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study

medRxiv(2020)10.1101/2020.09.08.20190975

N/A

0DataRank · unranked

30 citations

Tomoko Nakanishi, Vincent Mooser, David Morrison, Tala Abdullah, Olumide Adeleye +11 more

Osteocyte Transcriptome Mapping Identifies a Molecular Landscape Controlling Skeletal Homeostasis and Susceptibility to Skeletal Disease

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.20.051409

N/A

0DataRank · unranked

11 citations

John P. Kemp, John G. Logan, Elena J. Ghirardello, C. Marcelo Sergio, Michael R.G. Dack +32 more

An Effector Index to Predict Causal Genes at GWAS Loci

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.28.171561

N/A

0DataRank · unranked

11 citations

Lai Jiang, Nicholas A. Vulpescu, Megan S. Hogan, Siyuan Chen, John Morris +12 more

Failure to replicate the association of rare loss-of-function variants in type I IFN immunity genes with severe COVID-19

medRxiv(2020)10.1101/2020.12.18.20248226

N/A

0DataRank · unranked

10 citations

Guillaume Butler‐Laporte, Ning Shang, Chen Weng, Atlas Khan, Manal Alaamery +44 more

Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps

Nature Medicine(2021)10.1038/s41591-021-01549-6

N/A

0DataRank · unranked

445 citations

Adebowale Adeyemo, Mary K. Balaconis, Deanna R. Darnes, Segun Fatumo, Palmira Granados Moreno +22 more

A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity

Nature Medicine(2021)10.1038/s41591-021-01281-1

N/A

0DataRank · unranked

304 citations

Guillaume Butler‐Laporte, Tomoko Nakanishi, David Morrison, Jonathan Afilalo, Marc Afilalo +36 more

Dnmt3a -mutated clonal hematopoiesis promotes osteoporosis

The Journal of Experimental Medicine(2021)10.1084/jem.20211872

N/A

0DataRank · unranked

158 citations

Abhishek Niroula, Veronica Shkolnik, Marie McConkey, Amy Lin, Mikołaj Słabicki +23 more

J. Brent Richards

Indexed papers

Top data-sharing exemplar

Papers