Stephen F. Traynelis

NeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.684Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Three-dimensional missense tolerance ratio analysis

Genome Research(2021)10.1101/gr.275528.121

Top 29%

0.684DataRank

Top 29%27 citations

Anders S. Kristensen, Polina Lyuboslavsky, Stephen F. Traynelis, Riley E. Perszyk

Papers

Driven by 35 papers — median percentile 71. Top paper: “Three-dimensional missense tolerance ratio analysis”.

Three-dimensional missense tolerance ratio analysis

Genome Research(2021)10.1101/gr.275528.121

Top 29%

0.684DataRank

Top 29%27 citations

Anders S. Kristensen, Polina Lyuboslavsky, Stephen F. Traynelis, Riley E. Perszyk

Phase 1 Clinical Results for NP10679, a pH‐sensitive GluN2B‐selective N‐methyl‐d‐aspartate Receptor Inhibitor

Clinical Pharmacology in Drug Development(2023)10.1002/cpdd.1217

N/A

0.418DataRank · unranked

9 citations

Stephen F. Traynelis, Raymond Dingledine, George W. Koszalka, Daniel T. Laskowitz, Robert Zaczek

Epilepsy Benchmarks Area III: Improved Treatment Options for Controlling Seizures and Epilepsy-Related Conditions Without Side Effects

Epiliepsy currents/Epilepsy currents(2020)10.1177/1535759719895279

N/A

0DataRank · unranked

19 citations

Dennis Dlugos, David C. Henshall, Heather C. Mefford, Michael A. Rogawski, Kevin J. Staley +4 more

Hodgkin–Huxley–Katz Prize Lecture: Genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif

The Journal of Physiology(2020)10.1113/jp278086

N/A

0DataRank · unranked

26 citations

Scott J. Myers, Hongjie Yuan, Alasdair J. Gibb, Hiro Furukawa, Alexander I. Sobolevsky +2 more

Recurrent seizure‐related GRIN1 variant: Molecular mechanism and targeted therapy

Annals of Clinical and Translational Neurology(2021)10.1002/acn3.51406

N/A

0DataRank · unranked

39 citations

Rui Song, Wenjuan Chen, Katie L. Strong, Daniel W. Shrey, Satyanarayana Gedela +4 more

Automated Intracellular Pharmacological Electrophysiology for Ligand-Gated Ionotropic Receptor and Pharmacology Screening

Molecular Pharmacology(2021)10.1124/molpharm.120.000195

N/A

0DataRank · unranked

13 citations

Mighten C. Yip, Ona McConnell, Eric T. Wang, Andrew Jenkins, Stephen F. Traynelis +2 more

A de novo GRIN1 Variant Associated With Myoclonus and Developmental Delay: From Molecular Mechanism to Rescue Pharmacology

Frontiers in Genetics(2021)10.3389/fgene.2021.694312

N/A

0DataRank · unranked

8 citations

Weiting Tang, Nidhi Kaur Bhatia, Yuchen Xu, Nabina Paudyal, Ding Liu +11 more

Loss of Grin2a Causes a Transient Delay in the Electrophysiological Maturation of Hippocampal Parvalbumin Interneurons: A Possible Mechanism for Transient Seizure Burden in Patients with Null GRIN2A Variants

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.29.474447

N/A

0DataRank · unranked

3 citations

Anna Vlachos, Chiara Klöckner, Ilona Krey, Tue G. Banke, Nima Shariatzadeh +14 more

Conserved patterns across ion channels correlate with variant pathogenicity and clinical phenotypes

Brain(2022)10.1093/brain/awac305

N/A

0DataRank · unranked

26 citations

Eduardo Pérez‐Palma, Ludovica Montanucci, Michael Nothnagel, Rikke S. Møller, Stéphanie Schorge +8 more

Overlapping cortical malformations in patients with pathogenic variants in GRIN1 and GRIN2B

Journal of Medical Genetics(2022)10.1136/jmedgenet-2021-107971

N/A

0DataRank · unranked

13 citations

Annie Laquerrière, Florent Marguet, Scott J. Myers, Yuan Hongjie, Diana Baralle +24 more

Compound‐heterozygous GRIN2A null variants associated with severe developmental and epileptic encephalopathy

Epilepsia(2022)10.1111/epi.17394

N/A

0DataRank · unranked

8 citations

Claudine Rieubland, Sabina Gallati, Sukhan Kim, Scott J. Myers, Vincent Z. Peterson +5 more

Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry

Neuropsychopharmacology(2023)10.1038/s41386-023-01614-3

N/A

0DataRank · unranked

108 citations

Hongjie Yuan, Riley E. Perszyk, Tue G. Banke, Hao Xing, Ming‐Chi Tsai +3 more

Loss of Grin2a causes a transient delay in the electrophysiological maturation of hippocampal parvalbumin interneurons

Communications Biology(2023)10.1038/s42003-023-05298-9

N/A

0DataRank · unranked

38 citations

Anna Vlachos, Chiara Klöckner, Ilona Krey, Tue G. Banke, Nima Shariatzadeh +14 more

Classification of missense variants in the N-methyl-d-aspartate receptor GRIN gene family as gain- or loss-of-function

Human Molecular Genetics(2023)10.1093/hmg/ddad104

N/A

0DataRank · unranked

25 citations

Hongjie Yuan, Riley E. Perszyk, Jing Zhang, Sukhan Kim, Kelsey A. Nocilla +7 more

Clinical and functional consequences of GRIA variants in patients with neurological diseases

Cellular and Molecular Life Sciences(2023)10.1007/s00018-023-04991-6

N/A

0DataRank · unranked

19 citations

Riley E. Perszyk, Nana Liu, Yuchen Xu, Subhrajit Bhattacharya, Gil Shaulsky +25 more

Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model

ACS Chemical Neuroscience(2023)10.1021/acschemneuro.2c00779

N/A

0DataRank · unranked

16 citations

Michael C. Regan, Scott J. Myers, Kelsey A. Nocilla, Nicholas S. Akins, Yesim A. Tahirovic +6 more

GPR37L1 controls maturation and organization of cortical astrocytes during development

Glia(2023)10.1002/glia.24375

N/A

0DataRank · unranked

15 citations

Chad R. Camp, Juleva K. Doan, Stephen F. Traynelis, Steven A. Sloan, Randy A. Hall +1 more

Clinical features, functional consequences, and rescue pharmacology of missense GRID1 and GRID2 human variants

Human Molecular Genetics(2023)10.1093/hmg/ddad188

N/A

0DataRank · unranked

13 citations

Kathryn B. Garber, Riley E. Perszyk, Cara T Khayat, Steven A. Kell, Maki Kaneko +22 more

Functional effects of disease-associated variants reveal that the S1–M1 linker of the NMDA receptor critically controls channel opening

Cellular and Molecular Life Sciences(2023)10.1007/s00018-023-04705-y

N/A

0DataRank · unranked

11 citations

Miranda J. McDaniel, Riley E. Perszyk, Sukhan Kim, Gerarda Cappuccio, Kevin A. Shapiro +13 more

Development of a Dihydroquinoline–Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor

ACS Chemical Neuroscience(2023)10.1021/acschemneuro.3c00181

N/A

0DataRank · unranked

6 citations

Nicholas S. Akins, Peipei Ma, Yao Jing, Sharon A. Swanger, Savita K. Sharma +22 more

Additional Depth to the NMDA Receptor Hypofunction and Parvalbumin Cell Dysfunction Hypotheses of Schizophrenia

Biological Psychiatry(2023)10.1016/j.biopsych.2023.06.007

N/A

0DataRank · unranked

1 citations

Stephen F. Traynelis, Chad R. Camp

Epithelial N-methyl-D-aspartate (NMDA) receptors mediate renal vasodilation by affecting kidney autoregulation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.04.569973

N/A

0DataRank · unranked

2 citations

Jasmine Lim, Hong Wang, Brandi M. Wynne, Peipei Ma, Yao Jing +6 more

Molecular mechanism of ligand gating and opening of NMDA receptor

Nature(2024)10.1038/s41586-024-07742-0

N/A

0DataRank · unranked

54 citations

Max Epstein, Russell G. Fritzemeier, Nicholas S. Akins, Srinu Paladugu, Elijah Z. Ullman +4 more

Astrocytic PAR1 and mGluR2/3 control synaptic glutamate time course at hippocampal CA1 synapses

Glia(2024)10.1002/glia.24579

N/A

0DataRank · unranked

5 citations

Jae Hong Yoo, Shashank M. Dravid, Guido Mannaioni, Elizabeth N. Krizman, Myunghoon Lee +6 more

Selective Cell-Surface Expression of Triheteromeric NMDA Receptors

Methods in molecular biology(2024)10.1007/978-1-0716-3830-9_5

N/A

0DataRank · unranked

3 citations

Stephen F. Traynelis, Kasper B. Hansen, Feng Yi

Structural basis for channel gating and blockade in tri-heteromeric GluN1-2B-2D NMDA receptor

Neuron(2025)10.1016/j.neuron.2025.01.013

N/A

0DataRank · unranked

17 citations

Max Epstein, Tue G. Banke, Riley E. Perszyk, Noriko Simorowski, Srinu Paladugu +4 more

GRIN2A null variants confer a high risk for early-onset schizophrenia and other mental disorders and potentially enable precision therapy

Molecular Psychiatry(2025)10.1038/s41380-025-03279-4

N/A

0DataRank · unranked

7 citations

Andrea Eoli, Ilona Krey, Bernt Popp, Vincent Strehlow, Dirk Alexander Wittekind +27 more

Mechanism of conductance control and neurosteroid binding in NMDA receptors

Nature(2025)10.1038/s41586-025-09695-4

N/A

0DataRank · unranked

7 citations

Ruben Steigerwald, Elijah Z. Ullman, Max Epstein, Srinu Paladugu, Dennis C. Liotta +3 more

The thrombin receptor PAR1 orchestrates changes in lymphatic endothelial cell junction morphology to augment lymphatic drainage during lung injury

Nature Cardiovascular Research(2025)10.1038/s44161-025-00681-7

N/A

0DataRank · unranked

6 citations

Camila Ceballos Paredes, Barbara D. Summers, Jade Palmer-Johnson, Anjali Trivedi, A.R. Bhagwani +7 more

Synaptic dysregulation in a mouse model of GRIN2D developmental and epileptic encephalopathy

Brain(2025)10.1093/brain/awaf125

N/A

0DataRank · unranked

5 citations

Jane Simko, Chad R. Camp, Christine J. Liu, Wanqi Wang, Damian J. Williams +23 more

Inhibition of GluN2B-containing N -methyl- D- aspartate receptors by radiprodil

Brain(2025)10.1093/brain/awaf355

N/A

0DataRank · unranked

2 citations

Michael C. Regan, Riley E. Perszyk, Lu Zhang, Hao Xing, Jiahui Chen +22 more

Striatal GluN2A gene suppression reduces L-DOPA-induced abnormal involuntary movements in parkinsonian rats

Neuropharmacology(2025)10.1016/j.neuropharm.2025.110616

N/A

0DataRank · unranked

2 citations

Brik Kochoian, Stefano Coletta, Oskar Laur, Xinping Huang, Cassandra Bure +5 more

Modelling and treating GRIN2A developmental and epileptic encephalopathy in mice

Brain(2020)10.1093/brain/awaa147

N/A

0DataRank · unranked

83 citations

Christopher D. Bostick, Heather E. Olson, Jurrian Peters, Chad R. Camp, Daniel Krizay +21 more

Discrete interneuron subsets participate in GluN1/GluN3A excitatory glycine receptor (eGlyR)-mediated regulation of hippocampal network activity throughout development and evolution

Research Square(2025)10.21203/rs.3.rs-7822078/v1

N/A

0DataRank · unranked

0 citations

June Hoan Kim, Anna Vlachos, Vivek Mahadevan, Adam Caccavano, Tue G. Banke +32 more

Negative allosteric modulation of GluN1/GluN3 NMDA receptors

Neuropharmacology(2020)10.1016/j.neuropharm.2020.108117

N/A

0DataRank · unranked

37 citations

Feng Yi, Matthew P. Epplin, Ding Liu, Samantha L. Summer, Ruth Mizu +11 more

Stephen F. Traynelis

Indexed papers

Top data-sharing exemplar

Papers