Alfonso Eirin

Also affiliated with WinnMed

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 40 papers. Top paper: “Obesity-driven mitochondrial dysfunction in human adipose tissue-derived mesenchymal stem/stromal cells involves epigenetic changes”.

Obesity-driven mitochondrial dysfunction in human adipose tissue-derived mesenchymal stem/stromal cells involves epigenetic changes

Cell Death and Disease(2024)10.1038/s41419-024-06774-8

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0.780DataRank · unranked

32 citations

Roman Thaler, Logan M. Glasstetter, Xing Li, Xiangyang Zhu, Andrew C. Osborne +6 more

Metabolic syndrome increases senescence-associated micro-RNAs in extracellular vesicles derived from swine and human mesenchymal stem/stromal cells

Cell Communication and Signaling(2020)10.1186/s12964-020-00624-8

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0DataRank · unranked

57 citations

Yu Meng, Xiangyang Zhu, Ishran M. Saadiq, Kyra L. Jordan, Alfonso Eirin +2 more

Extracellular vesicles released by adipose tissue-derived mesenchymal stromal/stem cells from obese pigs fail to repair the injured kidney

Stem Cell Research(2020)10.1016/j.scr.2020.101877

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0DataRank · unranked

54 citations

Christopher M. Ferguson, Xiang-Yang Zhu, Ishran M. Saadiq, Hui Tang, Amir Lerman +2 more

Upregulated tumor necrosis factor-α transcriptome and proteome in adipose tissue-derived mesenchymal stem cells from pigs with metabolic syndrome

Cytokine(2020)10.1016/j.cyto.2020.155080

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0DataRank · unranked

45 citations

Alfonso Eirin, Hui Tang, Xiang-Yang Zhu, Amir Lerman, Lilach O. Lerman +1 more

Renal fibrosis detected by diffusion-weighted magnetic resonance imaging remains unchanged despite treatment in subjects with renovascular disease

Scientific Reports(2020)10.1038/s41598-020-73202-0

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0DataRank · unranked

19 citations

Alfonso Eirin, Abdelrhman Abumoawad, Ahmed Saad, Kai Jiang, Ahmad F. Hedayat +5 more

General Public’s Information-Seeking Patterns of Topics Related to Obesity: Google Trends Analysis

JMIR Public Health and Surveillance(2020)10.2196/20923

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0DataRank · unranked

17 citations

Sajan Jiv Singh Nagpal, Neha Pawar, Lilach O. Lerman, Alfonso Eirin, Aditya S. Pawar

Metabolic Syndrome Alters the Cargo of Mitochondria-Related microRNAs in Swine Mesenchymal Stem Cell-Derived Extracellular Vesicles, Impairing Their Capacity to Repair the Stenotic Kidney

Stem Cells International(2020)10.1155/2020/8845635

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0DataRank · unranked

16 citations

Xiang-Yang Zhu, Hui Tang, Kyra L. Jordan, Amir Lerman, Lilach O. Lerman +2 more

Renovascular Hypertension Induces Myocardial Mitochondrial Damage, Contributing to Cardiac Injury and Dysfunction in Pigs With Metabolic Syndrome

American Journal of Hypertension(2020)10.1093/ajh/hpaa202

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0DataRank · unranked

15 citations

Mohamed C Farah, Xiang-Yang Zhu, Lei Zhang, Hui Tang, Kyra L. Jordan +5 more

Experimental Renovascular Disease Induces Endothelial Cell Mitochondrial Damage and Impairs Endothelium-Dependent Relaxation of Renal Artery Segments

American Journal of Hypertension(2020)10.1093/ajh/hpaa047

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7 citations

Xiang-Yang Zhu, Ishran M. Saadiq, Kyra L. Jordan, Amir Lerman, Lilach O. Lerman +2 more

Hypoxic preconditioning induces epigenetic changes and modifies swine mesenchymal stem cell angiogenesis and senescence in experimental atherosclerotic renal artery stenosis

Stem Cell Research & Therapy(2021)10.1186/s13287-021-02310-z

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0DataRank · unranked

90 citations

Roman Thaler, Busra B. Goksu, Sabena M. Conley, Hayder Al-Khafaji, Arjunmohan Mohan +13 more

The Micro-RNA Cargo of Extracellular Vesicles Released by Human Adipose Tissue-Derived Mesenchymal Stem Cells Is Modified by Obesity

Frontiers in Cell and Developmental Biology(2021)10.3389/fcell.2021.660851

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0DataRank · unranked

63 citations

Yu Meng, Xiang-Yang Zhu, Yongxin Li, Ishran M. Saadiq, Kyra L. Jordan +5 more

Metabolic Syndrome Is Associated With Altered mRNA and miRNA Content in Human Circulating Extracellular Vesicles

Frontiers in Endocrinology(2021)10.3389/fendo.2021.687586

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14 citations

Yu Meng, Xiangyang Zhu, André J. van Wijnen, Alfonso Eirin, Lilach O. Lerman +1 more

Intrarenal modulation of NF-κB activity attenuates cardiac injury in a swine model of CKD: a renal-cardio axis

American Journal of Physiology-Renal Physiology(2021)10.1152/ajprenal.00158.2021

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0DataRank · unranked

17 citations

Jason Engel, Michael E. Hall, Alfonso Eirin, Gene L. Bidwell, Alejandro Chade

Duodenal mucosal mitochondrial gene expression is associated with delayed gastric emptying in diabetic gastroenteropathy

JCI Insight(2021)10.1172/jci.insight.143596

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15 citations

Daniel R. O’Brien, Mayank Sharma, Karl N. Miller, Peter D. Adams, João F. Passos +4 more

Renal Revascularization Attenuates Myocardial Mitochondrial Damage and Improves Diastolic Function in Pigs with Metabolic Syndrome and Renovascular Hypertension

Journal of Cardiovascular Translational Research(2021)10.1007/s12265-021-10155-3

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10 citations

Shasha Yu, Christopher M. Ferguson, Xiangyang Zhu, Hui Tang, Kyra L. Jordan +7 more

Differentially Expressed Functional LncRNAs in Human Subjects With Metabolic Syndrome Reflect a Competing Endogenous RNA Network in Circulating Extracellular Vesicles

Frontiers in Molecular Biosciences(2021)10.3389/fmolb.2021.667056

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9 citations

Yu Meng, Yuanhang Liu, André J. van Wijnen, Alfonso Eirin, Lilach O. Lerman +1 more

Cellular senescence: the good, the bad and the unknown

Nature Reviews Nephrology(2022)10.1038/s41581-022-00601-z

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0DataRank · unranked

1109 citations

LaTonya J. Hickson, Alfonso Eirin, James L. Kirkland, Lilach O. Lerman, Weijun Huang

IL-10 partly mediates the ability of MSC-derived extracellular vesicles to attenuate myocardial damage in experimental metabolic renovascular hypertension

Frontiers in Immunology(2022)10.3389/fimmu.2022.940093

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0DataRank · unranked

22 citations

Siting Hong, Xiangyang Zhu, Lei Zhang, Hui Tang, Kyra L. Jordan +6 more

Renal mitochondrial injury in the pathogenesis of CKD: mtDNA and mitomiRs

Clinical Science(2022)10.1042/cs20210512

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0DataRank · unranked

20 citations

Alejandro Chade, Alfonso Eirin, María V. Irazabal

Microvascular remodeling and altered angiogenic signaling in human kidneys distal to occlusive atherosclerotic renal artery stenosis

Nephrology Dialysis Transplantation(2022)10.1093/ndt/gfac156

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0DataRank · unranked

14 citations

Xiangyang Zhu, Alfonso Eirin, Aditya S. Pawar, Sabena M. Conley, Amrutesh S. Puranik +10 more

Effect of Hypoxia Preconditioning on the Regenerative Capacity of Adipose Tissue Derived Mesenchymal Stem Cells in a Model of Renal Artery Stenosis

Stem Cells(2022)10.1093/stmcls/sxac073

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0DataRank · unranked

9 citations

Arjunmohan Mohan, Busra Isik, Busra B. Goksu, Roman Thaler, Xiang Zhu +12 more

Effects of Elamipretide on Autophagy in Renal Cells of Pigs with Metabolic Syndrome

Cells(2022)10.3390/cells11182891

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6 citations

Ramyar Ghandriz, Sarosh Siddiqi, Xiangyang Zhu, Ishran M. Saadiq, Kyra L. Jordan +6 more

Autologous Extracellular Vesicles Attenuate Cardiac Injury in Experimental Atherosclerotic Renovascular Disease More Effectively Than Their Parent Mesenchymal Stem/Stromal Cells

Stem Cell Reviews and Reports(2022)10.1007/s12015-022-10473-2

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4 citations

Xiangyang Zhu, Yamei Jiang, Lei Zhang, Hui Tang, Kyra L. Jordan +6 more

HFpEF in CKD is Associated with Elevated TNF‐α/IL‐6 Inflammatory Signaling from the Kidney

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3478

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1 citations

Alfonso Eirin, Alejandro Chade

Renal inflammatory signaling alters cardiomyocyte kinetics and lead to HFpEF in CKD: A mechanistic proof of concept study

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r4578

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0DataRank · unranked

0 citations

Tamer Mohamed, Alfonso Eirin, Alejandro Chade

Kidney Intrinsic Mechanisms as Novel Targets in Renovascular Hypertension

Hypertension(2023)10.1161/hypertensionaha.123.21362

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0DataRank · unranked

14 citations

Alejandro Chade, Lilach O. Lerman, Alfonso Eirin

Diabetic kidney disease induces transcriptome alterations associated with angiogenesis activity in human mesenchymal stromal cells

Stem Cell Research & Therapy(2023)10.1186/s13287-023-03269-9

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0DataRank · unranked

13 citations

Sabena M. Conley, Alfonso Eirin, Eric A. Zimmerman Zuckerman, Anastasia Smith, Cody C. Gowan +12 more

Metabolic Syndrome Induces Epigenetic Alterations in Mitochondria-Related Genes in Swine Mesenchymal Stem Cells

Cells(2023)10.3390/cells12091274

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0DataRank · unranked

8 citations

Sara Kazeminia, Logan M. Glasstetter, Rahele A. Farahani, Xiangyang Zhu, Hui Tang +6 more

Obesity Blunts the Effect of Mesenchymal Stem Cell-Derived Extracellular Vesicles

Kidney International Reports(2023)10.1016/j.ekir.2023.06.009

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0DataRank · unranked

7 citations

Siting Hong, Xiangyang Zhu, Mina H. Alsaeedi, Hui Tang, James D. Krier +7 more

Altered immune cell phenotypes within chronically ischemic human kidneys distal to occlusive renal artery disease

American Journal of Physiology-Renal Physiology(2023)10.1152/ajprenal.00234.2023

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0DataRank · unranked

7 citations

Nattawat Klomjit, Aditya S. Pawar, Amrutesh S. Puranik, Zhi-Zhang Yang, Esther Lutgens +5 more

Renal ischemia alters the transcriptomic and epigenetic profile of inflammatory genes in swine scattered tubular-like cells

Clinical Science(2023)10.1042/cs20230555

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4 citations

Xiang Zhu, Hui Tang, Kyra L. Jordan, Ishran M. Saadiq, Sandra M. Herrmann +5 more

Dyslipidemia-induced renal fibrosis related to ferroptosis and endoplasmic reticulum stress

Journal of Lipid Research(2024)10.1016/j.jlr.2024.100610

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0DataRank · unranked

14 citations

Xiangyang Zhu, Kyra L. Jordan, Yong‐Xin Li, Sabena M. Conley, Hui Tang +5 more

Chronic kidney disease and left ventricular diastolic dysfunction (CKD-LVDD) alter cardiac expression of mitochondria-related genes in swine

Translational research(2024)10.1016/j.trsl.2023.12.004

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0DataRank · unranked

11 citations

Rhys Sitz, Taylor J. Kelty, Elizabeth A. McCarthy, Darla L. Tharp, R. Scott Rector +2 more

The impact of hypoxia preconditioning on mesenchymal stem cells performance in hypertensive kidney disease

Stem Cell Research & Therapy(2024)10.1186/s13287-024-03778-1

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0DataRank · unranked

10 citations

Naba Farooqui, Arjunmohan Mohan, Kamalnath Sankaran Rajagopalan, Xing Li, Xiang Zhu +9 more

Role of mitochondria in endogenous renal repair

Clinical Science(2024)10.1042/cs20231331

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10 citations

Alfonso Eirin, Sara Kazeminia

Tumor necrosis factor-stimulated gene-6 inhibits endoplasmic reticulum stress in the ischemic mouse kidney

iScience(2024)10.1016/j.isci.2024.111454

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2 citations

Xing Li, Xiang-Yang Zhu, Hui Tang, Brandon Lu, Fei Yuan +9 more

A New Model of Chronic Kidney Disease, Metabolic Derangements, and Heart Failure with Preserved Ejection Fraction in Aging Swine

American Journal of Nephrology(2025)10.1159/000543327

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0DataRank · unranked

4 citations

Darla L. Tharp, Rhys Sitz, Elizabeth A. McCarthy, Kumar Shivam, Sara Kazeminia +2 more

When in doubt, pig it out: a versatile translational platform to study CKD, HFpEF, and CKM syndrome

American Journal of Physiology-Heart and Circulatory Physiology(2025)10.1152/ajpheart.00548.2025

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0DataRank · unranked

1 citations

Alejandro Chade, Alfonso Eirin

Oxidative Stress and Mitochondrial Abnormalities Contribute to Decreased Endothelial Nitric Oxide Synthase Expression and Renal Disease Progression in Early Experimental Polycystic Kidney Disease

International Journal of Molecular Sciences(2020)10.3390/ijms21061994

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0DataRank · unranked

62 citations

Tania T. Barnatan, Ali Kahveci, Alexis Adrián, Jennifer Arroyo, Alfonso Eirin +6 more

Systemic MOTS-c levels are increased in adults with obesity in association with metabolic dysregulation and remain unchanged after weight loss

Journal of Clinical & Translational Endocrinology(2025)10.1016/j.jcte.2025.100429

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0DataRank · unranked

0 citations

Fei Yuan, Xiangyang Zhu, Hui Tang, Dilbar Abdurakhimoova, James Krier +5 more