Nathan P. Coussens

Frederick National Laboratory for Cancer Research

Also affiliated with National Center for Advancing Translational Sciences

Biochemistry, Genetics and Molecular BiologyComputer ScienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.685Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems–based Resource

Molecular Cancer Therapeutics(2023)10.1158/1535-7163.mct-23-0267

Top 29%

0.685DataRank

Top 29%24 citations

Mark W. Kunkel, Stephen L. White, Donn G. Wishka, Omar D. Lopez, Lori Bowles +16 more

Papers

Driven by 22 papers — median percentile 71. Top paper: “Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems–based Resource”.

Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems–based Resource

Molecular Cancer Therapeutics(2023)10.1158/1535-7163.mct-23-0267

Top 29%

0.685DataRank

Top 29%24 citations

Mark W. Kunkel, Stephen L. White, Donn G. Wishka, Omar D. Lopez, Lori Bowles +16 more

Addressing Compound Reactivity and Aggregation Assay Interferences: Case Studies of Biochemical High-Throughput Screening Campaigns Benefiting from the National Institutes of Health Assay Guidance Manual Guidelines

SLAS DISCOVERY(2021)10.1177/24725552211026239

N/A

0DataRank · unranked

12 citations

Douglas S. Auld, Jonathan R. Thielman, Bridget K. Wagner, Jayme L. Dahlin, Nathan P. Coussens

Assay Guidance Manual for Drug Discovery: Technologies That Matter

SLAS TECHNOLOGY(2021)10.1177/24726303211056338

N/A

0DataRank · unranked

1 citations

Nathan P. Coussens, Jayme L. Dahlin, G. Sitta Sittampalam, Sarine Markossian

Discovery of Novel Small-Molecule Scaffolds for the Inhibition and Activation of WIP1 Phosphatase from a RapidFire Mass Spectrometry High-Throughput Screen

ACS Pharmacology & Translational Science(2022)10.1021/acsptsci.2c00147

N/A

0DataRank · unranked

11 citations

Yuhong Fang, Dingyin Tao, Harichandra D. Tagad, Hongmao Sun, Yuhong Wang +13 more

Discovery of Small-Molecule VapC1 Nuclease Inhibitors by Virtual Screening and Scaffold Hopping from an Atomic Structure Revealing Protein–Protein Interactions with a Native VapB1 Inhibitor

Journal of Chemical Information and Modeling(2022)10.1021/acs.jcim.1c01188

N/A

0DataRank · unranked

5 citations

Nathan P. Coussens, Carina Danchik, Leah M. Wachsmuth, Mark J. Henderson, Samarjit Patnaik +5 more

The NCATS Assay Guidance Manual programme: advancing the practice and rigour of preclinical translation

Nature Reviews Drug Discovery(2022)10.1038/d41573-022-00170-7

N/A

0DataRank · unranked

4 citations

Kyle R. Brimacombe, G. Sitta Sittampalam, A Grossman, Nathan P. Coussens, James Inglese +5 more

Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs

Cancer Research Communications(2023)10.1158/2767-9764.crc-23-0193

N/A

0DataRank · unranked

18 citations

Nathan P. Coussens, Thomas Silvers, John Wright, Joel Morris, James H. Doroshow +2 more

Comparative Analysis of Drug-like EP300/CREBBP Acetyltransferase Inhibitors

ACS Chemical Biology(2023)10.1021/acschembio.3c00293

N/A

0DataRank · unranked

12 citations

Deepika R. Tripu, Samuel A. Barritt, Yihang Jing, Diamond Gallimore, Stephen C. Kales +11 more

Comparative analysis of drug-like EP300/CREBBP acetyltransferase inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.15.540887

N/A

0DataRank · unranked

3 citations

Deepika R. Tripu, Samuel A. Barritt, Yihang Jing, Diamond Gallimore, Stephen C. Kales +11 more

Editorial: Biophysical target engagement assays in chemical biology and pharmacological research

Frontiers in Cell and Developmental Biology(2023)10.3389/fcell.2023.1163966

N/A

0DataRank · unranked

2 citations

Nathan P. Coussens, Anton Simeonov, Bolormaa Baljinnyam

HTS384 NCI60: The Next Phase of the NCI60 Screen

Cancer Research(2024)10.1158/0008-5472.can-23-3031

N/A

0DataRank · unranked

24 citations

Nathan P. Coussens, Joel Morris, Ronald C. Taylor, Thomas S. Dexheimer, Eric M. Jones +3 more

Combination screen in multi-cell type tumor spheroids reveals interaction between aryl hydrocarbon receptor antagonists and E1 ubiquitin-activating enzyme inhibitor

SLAS DISCOVERY(2024)10.1016/j.slasd.2024.100186

N/A

0DataRank · unranked

7 citations

Nathan P. Coussens, Thomas Silvers, Eric M. Jones, Li Chen, Jianwen Fang +5 more

Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107561

N/A

0DataRank · unranked

5 citations

Dalibor Košek, Stewart R. Durell, Lisa M. Jenkins, Subrata Debnath, Nathan P. Coussens +6 more

Combinatorial screen of targeted agents with the PI3K inhibitors inavolisib, alpelisib, duvelisib, and copanlisib in multi-cell type tumor spheroids

SLAS DISCOVERY(2025)10.1016/j.slasd.2025.100222

N/A

0DataRank · unranked

9 citations

Zahra Davoudi, Nathan P. Coussens, Thomas Silvers, Joel Morris, Naoko Takebe +5 more

Combinatorial screen with apoptosis pathway targeted agents alrizomadlin, pelcitoclax, and dasminapant in multi-cell type tumor spheroids

SLAS DISCOVERY(2025)10.1016/j.slasd.2025.100230

N/A

0DataRank · unranked

5 citations

Thomas S. Dexheimer, Thomas Silvers, Phillip R. Sanchez, Li Chen, Melinda G. Hollingshead +4 more

RAS Pathway Inhibitors Combined with Targeted Agents Are Active in Patient-Derived Spheroids with Oncogenic KRAS Variants from Multiple Cancer Types

Cancer Research Communications(2025)10.1158/2767-9764.crc-24-0582

N/A

0DataRank · unranked

1 citations

Thomas S. Dexheimer, Nathan P. Coussens, Thomas Silvers, Raymond G. Fox, Samantha B. Kemp +7 more

High-throughput combination screening of Pidnarulex and other G-quadruplex ligands in multi-cell type tumor spheroids

SLAS DISCOVERY(2025)10.1016/j.slasd.2025.100284

N/A

0DataRank · unranked

1 citations

Nathan P. Coussens, Thomas Silvers, Poorva Juneja, Eric A. Jones, Steven D. Gore +4 more

Polymerase Ѳ inhibitors combinations with approved and investigational agents in patient-derived tumor multi-cell type (mct) spheroids

Experimental and Molecular Pathology(2025)10.1016/j.yexmp.2025.104978

N/A

0DataRank · unranked

2 citations

Thomas S. Dexheimer, Li Chen, Thomas Silvers, Eric M. Jones, Nathan P. Coussens +3 more

Ampyrone (4-Aminoantipyrine) is a Direct Agonist of Human Tyrosinase and Potential Therapeutic for Oculocutaneous Albinism and Disorders of Hypopigmentation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.13.682036

N/A

0DataRank · unranked

1 citations

Yuhong Wang, Nathan P. Coussens, Vijay K. Kalaskar, Zuhal Eraslan, Samuel Grondin +21 more

Targeted therapy combinations with ipatasertib in multi-cell type 3D tumor spheroid models

Academia oncology.(2025)10.20935/acadonco7726

N/A

0DataRank · unranked

0 citations

Naoko Takebe, Thomas S. Dexheimer, Thomas Silvers, Nathan P. Coussens, Melinda G. Hollingshead +2 more

Assay Guidance Manual for Drug Discovery: Robust or Go Bust

SLAS DISCOVERY(2021)10.1177/24725552211054044

N/A

0DataRank · unranked

11 citations

Nathan P. Coussens, Jayme L. Dahlin, G. Sitta Sittampalam, Sarine Markossian

RNA processing kinase inhibitors and epigenetic inhibitors in combination with oncology drugs or investigational agents in multi-cell type patient-derived tumor cell line spheroids

Cancer Chemotherapy and Pharmacology(2025)10.1007/s00280-025-04800-w

N/A

0DataRank · unranked

0 citations

Thomas S. Dexheimer, Thomas Silvers, Nathan P. Coussens, Eric M. Jones, Steven D. Gore +3 more

Nathan P. Coussens

Indexed papers

Top data-sharing exemplar

Papers