William P. Tansey

Also affiliated with Vanderbilt University Medical Center

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 27 papers. Top paper: “MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1”.

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

eLife(2021)10.7554/elife.60191

N/A

2.1DataRank · unranked

105 citations

Jing Wang, Clare M. Adams, Gregory C. Howard, Simona G. Codreanu, Stacy D. Sherrod +9 more

Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

eLife(2023)10.7554/elife.90683

N/A

0.652DataRank · unranked

18 citations

Jing Wang, Kristie L. Rose, Camden Jones, Purvi Patel, Tina Tsui +15 more

Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells

NAR Cancer(2022)10.1093/narcan/zcac007

N/A

0.442DataRank · unranked

18 citations

Chase M. Woodley, Jing Wang, Brian C. Grieb, Macey J. Slota, Kiana Guerrazzi +10 more

The SWI/SNF ATPase BRG1 facilitates multiple pro-tumorigenic gene expression programs in SMARCB1-deficient cancer cells

Oncogenesis(2022)10.1038/s41389-022-00406-6

N/A

0.425DataRank · unranked

16 citations

Jack N. Maxwell, Jing Wang, Cheyenne A. Jones, Grace T. Csaki, Andrea C. Florian +7 more

Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2408889121

N/A

0.385DataRank · unranked

12 citations

Brianna N. Smith, Jing Wang, Kevin B. Teuscher, Brian C. Grieb, Gregory C. Howard +12 more

Gene-specific quantification of nascent transcription following targeted degradation of endogenous proteins in cultured cells

STAR Protocols(2021)10.1016/j.xpro.2021.101000

N/A

0.385DataRank · unranked

12 citations

April M. Weissmiller, William P. Tansey, Alissa D. Guarnaccia

Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01529

N/A

0.360DataRank · unranked

10 citations

Jonathan J. Mills, Jianhua Tian, Changho Han, Kenneth M. Meyers, Jiqing Sai +12 more

Ribosome-directed cancer therapies: the tip of the iceberg?

Trends in Pharmacological Sciences(2025)10.1016/j.tips.2025.02.001

N/A

0.312DataRank · unranked

7 citations

William P. Tansey, Gregory C. Howard

Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.26.550648

N/A

0.165DataRank · unranked

2 citations

Jing Wang, Kristie L. Rose, Camden Jones, Purvi Patel, Tina Tsui +15 more

MYC Regulates a DNA Repair Gene Expression Program in Small Cell Carcinoma of the Ovary, Hypercalcemic Type

Cancers(2025)10.3390/cancers17132255

N/A

0.104DataRank · unranked

1 citations

Jing Wang, Cinthia N. Reed, Joy H. Creighton, Kaylee B. Garrison, Abigail N. Robertson +8 more

Reviewer #1 (Public Review): Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

(2023)10.7554/elife.90683.1.sa1

N/A

0DataRank · unranked

0 citations

Jing Wang, Kristie L. Rose, Purvi Patel, Tina Tsui, Andrea C. Florian +12 more

WD Repeat Domain 5 Inhibitors for Cancer Therapy: Not What You Think

Journal of Clinical Medicine(2024)10.3390/jcm13010274

N/A

0DataRank · unranked

18 citations

Stephen W. Fesik, William P. Tansey, April M. Weissmiller

Super-Enhancer Dysregulation in Rhabdoid Tumor Cells Is Regulated by the SWI/SNF ATPase BRG1

Cancers(2024)10.3390/cancers16050916

N/A

0DataRank · unranked

2 citations

Jing Wang, James R. Evans, Hannah R. Sisk, Carl B. Womack, Qi Liu +3 more

Mitotic gene regulation by the N-MYC-WDR5-PDPK1 nexus

BMC Genomics(2024)10.1186/s12864-024-10282-6

N/A

0DataRank · unranked

1 citations

Alexandria G. Williams, James R. Evans, Jing Wang, Alissa D. Guarnaccia, Andrea C. Florian +5 more

Author response: Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

(2024)10.7554/elife.90683.2.sa3

N/A

0DataRank · unranked

0 citations

Jing Wang, Kristie L. Rose, Camden Jones, Purvi Patel, Tina Tsui +15 more

Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

eLife(2024)10.7554/elife.90683.3

N/A

0DataRank · unranked

0 citations

Jing Wang, Kristie L. Rose, Camden Jones, Purvi Patel, Tina Tsui +15 more

WDR5 is a conserved regulator of protein synthesis gene expression

Nucleic Acids Research(2020)10.1093/nar/gkaa051

N/A

0DataRank · unranked

89 citations

Jing Wang, Gregory C. Howard, Alissa D. Guarnaccia, Chase M. Woodley, Erin R. Aho +10 more

eNRSA: a faster and more powerful approach for nascent transcriptome analysis

GigaScience(2025)10.1093/gigascience/giaf071

N/A

0DataRank · unranked

0 citations

Hua-Chang Chen, Scott W. Hiebert, Quanhu Sheng, William P. Tansey, Yu Shyr +2 more

Targeting MYC through WDR5

Molecular & Cellular Oncology(2020)10.1080/23723556.2019.1709388

N/A

0DataRank · unranked

32 citations

Clare M. Adams, Stephen W. Fesik, Christine M. Eischen, William P. Tansey, Lance R. Thomas

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through interaction with Host Cell Factor-1

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.22.164764

N/A

0DataRank · unranked

0 citations

Jing Wang, Clare M. Adams, Simona G. Codreanu, Stacy D. Sherrod, John McClean +8 more

Impact of WIN site inhibitor on the WDR5 interactome

Cell Reports(2021)10.1016/j.celrep.2020.108636

N/A

0DataRank · unranked

75 citations

Kristie L. Rose, Jing Wang, Bin Zhao, Tessa M. Popay, Christina Wang +13 more

Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2211297120

N/A

0DataRank · unranked

38 citations

Somenath Chowdhury, Kenneth M. Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren +15 more

WIN site inhibition disrupts a subset of WDR5 function

Scientific Reports(2022)10.1038/s41598-022-05947-9

N/A

0DataRank · unranked

38 citations

Jing Wang, Andrea C. Florian, Lance R. Thomas, Joy H. Creighton, Brittany K. Matlock +8 more

Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based Optimization

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00195

N/A

0DataRank · unranked

32 citations

Kenneth M. Meyers, Qiangqiang Wei, Jonathan J. Mills, Jianhua Tian, Joseph Alvarado +11 more

Elevating SOX2 Downregulates MYC through a SOX2:MYC Signaling Axis and Induces a Slowly Cycling Proliferative State in Human Tumor Cells

Cancers(2022)10.3390/cancers14081946

N/A

0DataRank · unranked

6 citations

Phillip J. Wilder, Tessa M. Popay, Jing Wang, Qi Liu, Achyuth Kalluchi +4 more

WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines

Oncogenesis(2023)10.1038/s41389-023-00477-z

N/A

0DataRank · unranked

22 citations

Kylie C. Moe, Jing Wang, L.A. Carver, Alexandria G. Williams, Alexander S. Romer +8 more

Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

(2023)10.7554/elife.90683.1

N/A

0DataRank · unranked

1 citations

Jing Wang, Kristie L. Rose, Purvi Patel, Tina Tsui, Andrea C. Florian +12 more