Byron Caughey

Government of the United States of America

Also affiliated with National Institute of Allergy and Infectious Diseases

Biochemistry, Genetics and Molecular BiologyNeuroscienceNursingMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 42 papers. Top paper: “Ring trial of 2nd generation RT‐QuIC diagnostic tests for sporadic CJD”.

Ring trial of 2nd generation RT‐QuIC diagnostic tests for sporadic CJD

Annals of Clinical and Translational Neurology(2020)10.1002/acn3.51219

N/A

1.7DataRank · unranked

56 citations

Bradley R. Groveman, Aaron Foutz, Matilde Bongianni, Franco Cardone, Neil McKenzie +17 more

High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01282-8

N/A

0.836DataRank · unranked

262 citations

Christina D. Orrú, Luis Concha‐Marambio, Simone Giaisi, Bradley R. Groveman, Carly M. Farris +13 more

Real-Time Quaking- Induced Conversion Assays for Prion Diseases, Synucleinopathies, and Tauopathies

Frontiers in Aging Neuroscience(2022)10.3389/fnagi.2022.853050

N/A

0.568DataRank · unranked

43 citations

Christina D. Orrú, Byron Caughey, Sarah Vascellari

Structure of an infectious mammalian prion

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.14.431014

N/A

0.550DataRank · unranked

38 citations

Forrest Hoyt, Cindi L. Schwartz, Bryan Hansen, Andrew G. Hughson, Efrosini Artikis +3 more

Pathogenic prion structures at high resolution

PLoS Pathogens(2022)10.1371/journal.ppat.1010594

N/A

0.515DataRank · unranked

30 citations

Heidi G. Standke, Efrosini Artikis, Forrest Hoyt, Allison Kraus, Byron Caughey

Cryo-EM structure of a natural prion: chronic wasting disease fibrils from deer

Acta Neuropathologica(2024)10.1007/s00401-024-02813-y

N/A

0.510DataRank · unranked

29 citations

Forrest Hoyt, Efrosini Artikis, Jakub Soukup, Andrew G. Hughson, Cindi L. Schwartz +5 more

PERFORMANCE OF αSYNUCLEIN RT-QUIC IN RELATION TO NEUROPATHOLOGICAL STAGING OF LEWY BODY DISEASE

medRxiv(2022)10.1101/2022.05.05.22274567

N/A

0.341DataRank · unranked

4 citations

Christina D. Orrú, Geidy E. Serrano, Douglas Galasko, Andrew G. Hughson, Bradley R. Groveman +5 more

Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau

FEBS Letters(2025)10.1002/1873-3468.70141

N/A

0.241DataRank · unranked

4 citations

Sofia Lövestam, Michael A. Metrick, Thomas Löhr, Pu Xu, Nicholas C. T. Gallagher +5 more

Cryo-EM structure of a natural prion: chronic wasting disease fibrils from deer

Research Square(2024)10.21203/rs.3.rs-5099451/v1

N/A

0.104DataRank · unranked

1 citations

Forrest Hoyt, Efrosini Artikis, Jakub Soukup, Andrew G. Hughson, Cindi L. Schwartz +5 more

Brazilin Removes Toxic Alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium

Journal of Molecular Biology(2021)10.1016/j.jmb.2021.166878

N/A

0DataRank · unranked

19 citations

Yuanzi Sun, Yong Xu, Mark Batchelor, M. Reilly, Iryna Benilova +10 more

Structure of anchorless RML prion reveals motif variation between strains

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.22.473909

N/A

0DataRank · unranked

10 citations

Heidi G. Standke, Efrosini Artikis, Cindi L. Schwartz, Bryan Hansen, Kunpeng Li +8 more

Cryo-EM structure of anchorless RML prion reveals variations in shared motifs between distinct strains

Nature Communications(2022)10.1038/s41467-022-30458-6

N/A

0DataRank · unranked

109 citations

Heidi G. Standke, Efrosini Artikis, Cindi L. Schwartz, Bryan Hansen, Kunpeng Li +9 more

Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease

Acta Neuropathologica Communications(2022)10.1186/s40478-022-01388-7

N/A

0DataRank · unranked

123 citations

Christina D. Orrú, Geidy E. Serrano, Douglas Galasko, Andrew G. Hughson, Bradley R. Groveman +5 more

Cryo-EM of prion strains from the same genotype of host identifies conformational determinants

PLoS Pathogens(2022)10.1371/journal.ppat.1010947

N/A

0DataRank · unranked

60 citations

Parvez Alam, Efrosini Artikis, Cindi L. Schwartz, Andrew G. Hughson, Brent Race +6 more

RT-QuIC and Related Assays for Detecting and Quantifying Prion-like Pathological Seeds of α-Synuclein

Biomolecules(2022)10.3390/biom12040576

N/A

0DataRank · unranked

56 citations

Parvez Alam, Byron Caughey, Ankit Srivastava

Cryo-EM of prion strains from the same genotype of host identifies conformational determinants

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.19.508587

N/A

0DataRank · unranked

4 citations

Parvez Alam, Efrosini Artikis, Cindi L. Schwartz, Andrew G. Hughson, Brent Race +6 more

Trajectories of neurodegeneration and seed amplification biomarkers prior to disease onset in individuals at risk of prion disease

medRxiv(2022)10.1101/2022.10.30.22281644

N/A

0DataRank · unranked

0 citations

Akın Nihat, Nour K. Majbour, Danielle Sequeira, Leah Holm-Mercer, Thomas Coysh +28 more

Seed amplification and neurodegeneration marker trajectories in individuals at risk of prion disease

Brain(2023)10.1093/brain/awad101

N/A

0DataRank · unranked

46 citations

Akın Nihat, Nour K. Majbour, Danielle Sequeira, Leah Holm-Mercer, Thomas Coysh +28 more

α-Synuclein seeding activity in duodenum biopsies from Parkinson’s disease patients

PLoS Pathogens(2023)10.1371/journal.ppat.1011456

N/A

0DataRank · unranked

33 citations

Christina D. Orrú, Bradley R. Groveman, Sabiha Parveen, Giuseppe Fenu, Giada Pisano +12 more

A novel subtype of sporadic Creutzfeldt–Jakob disease with PRNP codon 129MM genotype and PrP plaques

Acta Neuropathologica(2023)10.1007/s00401-023-02581-1

N/A

0DataRank · unranked

28 citations

Christina D. Orrú, Rabail Aslam, Yvonne Cohen, Amelia Silva-Rohwer, Seongki Lee +9 more

Tau seeding without tauopathy

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105545

N/A

0DataRank · unranked

9 citations

Efrosini Artikis, Brian D. Hitt, Joshua D. Beaver, Sandi Jo Estill, Kelly Gleason +6 more

Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection

PLoS Pathogens(2023)10.1371/journal.ppat.1011487

N/A

0DataRank · unranked

3 citations

Adela Malik, Daniel R. Sandoval, Christopher V. Barback, Christina D. Orrú, Heidi G. Standke +15 more

Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.19.545528

N/A

0DataRank · unranked

0 citations

Adela Malik, Daniel R. Sandoval, Christopher V. Barback, Christina D. Orrú, Heidi G. Standke +15 more

Enhanced quantitation of pathological α-synuclein in patient biospecimens by RT-QuIC seed amplification assays

PLoS Pathogens(2024)10.1371/journal.ppat.1012554

N/A

0DataRank · unranked

27 citations

Qinlu Wang, Christina D. Orrú, Manel Fernández, Yaroslau Compta, Bernardino Ghetti +5 more

Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces

PLoS Pathogens(2024)10.1371/journal.ppat.1012175

N/A

0DataRank · unranked

15 citations

Bradley R. Groveman, Andrew G. Hughson, Tomás Barrio, Kachi Isiofia, Brent Race +9 more

Large-scale validation of skin prion seeding activity as a biomarker for diagnosis of prion diseases

Acta Neuropathologica(2024)10.1007/s00401-023-02661-2

N/A

0DataRank · unranked

18 citations

Christina D. Orrú, Aaron Foutz, Mingxuan Ding, Jue Yuan, Syed Zahid Ali Shah +21 more

Seeding activity of human superoxide dismutase 1 aggregates in familial and sporadic amyotrophic lateral sclerosis postmortem neural tissues by real-time quaking-induced conversion

Acta Neuropathologica(2024)10.1007/s00401-024-02752-8

N/A

0DataRank · unranked

13 citations

Mikael Klingeborn, Eric P. Schultz, Erin L. Markham, Emily D. Reese, Parvez Alam +6 more

A same day α-synuclein RT-QuIC seed amplification assay for synucleinopathy biospecimens

npj Biosensing(2025)10.1038/s44328-024-00023-w

N/A

0DataRank · unranked

25 citations

Parvez Alam, Christina D. Orrú, Sarah Vascellari, Andrew G. Hughson, Wen‐Quan Zou +9 more

Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice

Journal of Clinical Investigation(2025)10.1172/jci186432

N/A

0DataRank · unranked

6 citations

Julia A. Callender, Joshua E. Mayfield, Daniel B. McClatchy, Daniel Ojeda-Juárez, Mahsa Pourhamzeh +26 more

How short is too short for amyloid fibrils?: Molecular dynamics of oligomers of infectious prion core structures

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110390

N/A

0DataRank · unranked

5 citations

Amitava Roy, Byron Caughey, Efrosini Artikis

Prions and protein aggregates as pathogens, self-propagating structures, biomarkers, and therapeutic targets

Microbiology and Molecular Biology Reviews(2025)10.1128/mmbr.00007-25

N/A

0DataRank · unranked

2 citations

Efrosini Artikis, Daniel Shoup, Christina D. Orrú, Parvez Alam, Sabiha Parveen +5 more

Classification of Tauopathies from Human Brain Homogenates through Salt-Modulated Tau Amplification

medRxiv(2025)10.1101/2025.08.05.25331458

N/A

0DataRank · unranked

1 citations

Michael A. Metrick, Pu Xu, Shunsuke Koga, Bernardino Ghetti, Dennis W. Dickson +3 more

Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies

Acta Neuropathologica(2020)10.1007/s00401-020-02160-8

N/A

0DataRank · unranked

479 citations

Niccolò Candelise, Simone Baiardi, Sabina Capellari, Giulia Giannini, Christina D. Orrú +10 more

Rational Generation of Monoclonal Antibodies and Intrabodies Selective for Pathogenic TDP-43

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.10.658846

N/A

0DataRank · unranked

0 citations

Sarah Louadi, Juliane Coutts, Ebrima Gibbs, Megan Y. Huang, Ryan J. Marina +10 more

A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases

Acta Neuropathologica Communications(2020)10.1186/s40478-020-0887-z

N/A

0DataRank · unranked

124 citations

Natalia Ferreira, Eri Saijo, Allison Kraus, Kathy L. Newell, Gianluigi Zanusso +4 more

Proteopathic Seed Amplification Assays for Neurodegenerative Disorders

Clinics in Laboratory Medicine(2020)10.1016/j.cll.2020.04.002

N/A

0DataRank · unranked

37 citations

Byron Caughey, Natalia Ferreira

Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns

Journal of Neuropathology & Experimental Neurology(2020)10.1093/jnen/nlaa109

N/A

0DataRank · unranked

34 citations

Ermias D. Belay, Eileen H. Bigio, Sebastian Brandner, Scott A. Brubaker, Byron Caughey +20 more

Cross-validation of the RT-QuIC assay for the antemortem detection of chronic wasting disease in elk

Prion(2020)10.1080/19336896.2020.1716657

N/A

0DataRank · unranked

32 citations

R. Donner, Davin M. Henderson, J Tennant, Edward A. Hoover, Matteo Manca +12 more

Brazilin Removes Toxic alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.29.318220

N/A

0DataRank · unranked

1 citations

Yuanzi Sun, Yong Xu, Mark Batchelor, M. Reilly, Iryna Benilova +10 more

A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases.

Apollo (University of Cambridge)(2020)10.17863/cam.50889

N/A

0DataRank · unranked

0 citations

Natalia Ferreira, Eri Saijo, Allison Kraus, Kathy L. Newell, Gianluigi Zanusso +4 more

Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease

The Lancet Neurology(2021)10.1016/s1474-4422(20)30477-4

N/A

0DataRank · unranked

346 citations

Brian S. Appleby, Jean‐Philippe Brandel, Byron Caughey, Steven Collins, Michael D. Geschwind +14 more

Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear

Scientific Reports(2021)10.1038/s41598-021-87295-8

N/A

0DataRank · unranked

44 citations

Jorge M. Charco, Jakob Plagenz, Christina D. Orrú, Nathanial D. Denkers, Michael A. Metrick +9 more