Tsuneya Ikezu

Also affiliated with Jacksonville College, WinnMed, Mayo Clinic in Florida

MedicineNeuroscienceBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

3.7Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues

Alzheimer s & Dementia(2020)10.1002/alz.12089

Top 6%

3.7DataRank

Top 6%196 citations

Annina M. DeLeo, Manveen K. Sethi, Kayo Takamatsu-Yukawa, Zijian Yang, Jina Ko +14 more

Papers

Driven by 38 papers — median percentile 94. Top paper: “Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues”.

Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues

Alzheimer s & Dementia(2020)10.1002/alz.12089

Top 6%

3.7DataRank

Top 6%196 citations

Annina M. DeLeo, Manveen K. Sethi, Kayo Takamatsu-Yukawa, Zijian Yang, Jina Ko +14 more

APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints

Nature Immunology(2023)10.1038/s41590-023-01627-6

N/A

0.794DataRank · unranked

198 citations

Neta Rosenzweig, Kilian L. Kleemann, Xiaoming Zhang, Wesley Nogueira Brandão, Milica A. Margeta +38 more

ATP1A3 as a target for isolating neuron-specific extracellular vesicles from human brain and biofluids

Science Advances(2023)10.1126/sciadv.adi3647

N/A

0.673DataRank · unranked

88 citations

Zhengrong Zhang, Nadia Sultana, Maria Ericsson, Yuka A. Martens, Min Sun +5 more

Selenoprotein P is a target for regulating extracellular vesicle biogenesis and secretion from activated microglia in vivo

Cell Reports(2024)10.1016/j.celrep.2024.115025

N/A

0.405DataRank · unranked

11 citations

Zhi Ruan, Bridgette Melvin, Ikshu Pandey, Seiko Ikezu, Tsuneya Ikezu +1 more

Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities

Molecular Psychiatry(2020)10.1038/s41380-020-0671-2

N/A

0DataRank · unranked

90 citations

Hana Yeh, Jean-Christophe Delpech, Maya E. Woodbury, Alicia A. Van Enoo, Zhi Ruan +17 more

Assessment of separation methods for extracellular vesicles from human and mouse brain tissues and human cerebrospinal fluids

Methods(2020)10.1016/j.ymeth.2020.02.002

N/A

0DataRank · unranked

81 citations

Weiwei Lin, Mei Chen, Samuel Hersh, Andrew Emili, Weiming Xia +2 more

Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses

Molecular & Cellular Proteomics(2020)10.1074/mcp.ra120.002079

N/A

0DataRank · unranked

44 citations

Alexander C. Jones, Qing Liu, Brent Aulston, Linnea Ransom, Janneca Ames +10 more

Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models

Acta Neuropathologica Communications(2020)10.1186/s40478-020-0890-4

N/A

0DataRank · unranked

32 citations

Kaitlin L. Ingraham Dixie, Lacin Koro, Takashi Watanabe, Kozo Kaibuchi, Tsuneya Ikezu +1 more

Crohn’s and Parkinson’s Disease-Associated LRRK2 Mutations Alter Type II Interferon Responses in Human CD14+ Blood Monocytes Ex Vivo

Journal of Neuroimmune Pharmacology(2020)10.1007/s11481-020-09909-8

N/A

0DataRank · unranked

24 citations

Lacin Koro, Benjamin Wolozin, Francis A. Farraye, Audrey Strongosky, Zbigniew K. Wszołek +1 more

Integrative Brain Transcriptome Analysis Links Complement Component 4 and HSPA2 to the APOE ε2 Protective Effect in Alzheimer Disease

medRxiv(2020)10.1101/2020.11.23.20235762

N/A

0DataRank · unranked

6 citations

Junming Hu, Jaeyoon Chung, Congcong Zhu, Gaoyuan Meng, Weiming Xia +8 more

Amyloid plaque deposition accelerates tau propagation via activation of microglia in a humanized APP mouse model

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.22.308015

N/A

0DataRank · unranked

4 citations

Jean-Christophe Delpech, Shawn Herron, Naotoshi Iwahara, Takashi Saito, Takaomi C. Saido +3 more

Enrichment of neurodegenerative microglia signature in brain-derived extracellular vesicles isolated from Alzheimer’s disease mouse model

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.05.369728

N/A

0DataRank · unranked

2 citations

Mark P. Jedrychowski, Naotoshi Iwahara, Mohammad Abdullah, Kristen D. Onos, Kelly J. Keezer +6 more

Alzheimer’s disease brain-derived tau-containing extracellular vesicles: Pathobiology and GABAergic neuronal transmission

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.15.992719

N/A

0DataRank · unranked

1 citations

Dhruba Pathak, Srinidhi Venkatesan Kalavai, Asuka Yoshii-Kitahara, Satoshi Muraoka, Kayo Takamatsu-Yukawa +11 more

Protein phosphatase 2A, complement component 4, and APOE genotype linked to Alzheimer’s disease using a systems biology approach

medRxiv(2020)10.1101/2020.11.20.20235051

N/A

0DataRank · unranked

0 citations

Yang You, Congcong Zhu, Gaoyuan Meng, Jaeyoon Chung, Rebecca Panitch +15 more

Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model

Molecular Neurodegeneration(2021)10.1186/s13024-021-00440-9

N/A

0DataRank · unranked

239 citations

Jean-Christophe Delpech, Shawn Herron, Naotoshi Iwahara, Maria Ericsson, Takashi Saito +4 more

Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease

Molecular Psychiatry(2021)10.1038/s41380-021-01266-z

N/A

0DataRank · unranked

64 citations

Junming Hu, Jaeyoon Chung, Congcong Zhu, Gaoyuan Meng, Weiming Xia +8 more

Proteomic Profiling of Extracellular Vesicles Separated from Plasma of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy

Aging and Disease(2021)10.14336/ad.2020.0908

N/A

0DataRank · unranked

30 citations

Annina M. DeLeo, Zijian Yang, Harutsugu Tatebe, Kayo Yukawa-Takamatsu, Seiko Ikezu +5 more

Enrichment of Phosphorylated Tau (Thr181) and Functionally Interacting Molecules in Chronic Traumatic Encephalopathy Brain-derived Extracellular Vesicles

Aging and Disease(2021)10.14336/ad.2020.1007

N/A

0DataRank · unranked

13 citations

Weiwei Lin, Kayo Takamatsu-Yukawa, Jianqiao Hu, Seiko Ikezu, Michael DeTure +4 more

Extracellular Hsp90α Detoxifies β-Amyloid Fibrils Through an NRF2 and Autophagy Dependent Pathway

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.16.440151

N/A

0DataRank · unranked

2 citations

Benjamin Lang, Thiago J. Borges, Yuka Okusha, Sachin Doshi, Suraya Yasmine +7 more

Extracellular vesicles as personalized medicine

Molecular Aspects of Medicine(2022)10.1016/j.mam.2022.101155

N/A

0DataRank · unranked

95 citations

Damian N. Di Florio, Katelyn A. Bruno, Tsuneya Ikezu, Keith L. March, Leslie T. Cooper +3 more

Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease

Alzheimer s & Dementia(2022)10.1002/alz.12607

N/A

0DataRank · unranked

38 citations

Yang You, Congcong Zhu, Gaoyuan Meng, Jaeyoon Chung, Rebecca Panitch +15 more

Using mechanical homogenization to isolate microglia from mouse brain tissue to preserve transcriptomic integrity

STAR Protocols(2022)10.1016/j.xpro.2022.101670

N/A

0DataRank · unranked

23 citations

Jean-Christophe Delpech, Charlotte Madore, Tsuneya Ikezu, Shawn Herron

Microglial WNT5A supports dendritic spines maturation and neuronal firing

Brain Behavior and Immunity(2022)10.1016/j.bbi.2022.11.003

N/A

0DataRank · unranked

22 citations

Maya E. Woodbury, Kaitlin L. Ingraham Dixie, Tsuneya Ikezu, Seiko Ikezu, Hana Yeh

Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia

Cell Reports(2022)10.1016/j.celrep.2022.110791

N/A

0DataRank · unranked

17 citations

Kayo Takamatsu-Yukawa, Yuzhi Wang, Margaret Ushman, Adam Labadorf, Maria Ericsson +3 more

Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease

Nature Neuroscience(2023)10.1038/s41593-023-01355-y

N/A

0DataRank · unranked

112 citations

Shawn Herron, Sebastian Silveira, Kilian L. Kleemann, Christian Gauthier, Dania Mallah +18 more

Recommendations for reproducibility of cerebrospinal fluid extracellular vesicle studies

Journal of Extracellular Vesicles(2023)10.1002/jev2.12397

N/A

0DataRank · unranked

53 citations

Setty M. Magaña, Júlia Costa, John P. Nolan, Tsuneya Ikezu, Laura J. Vella +18 more

Single‐extracellular vesicle (EV) analyses validate the use of L1 Cell Adhesion Molecule (L1CAM) as a reliable biomarker of neuron‐derived EVs

Journal of Extracellular Vesicles(2024)10.1002/jev2.12459

N/A

0DataRank · unranked

84 citations

Erden Eren, Pamela J. Yao, Elizabeth Calzada, Christopher J. Dunn, Olga V. Volpert +13 more

Extracellular Vesicle-Mediated Neuron–Glia Communications in the Central Nervous System

Journal of Neuroscience(2024)10.1523/jneurosci.1170-24.2024

N/A

0DataRank · unranked

26 citations

Yongjie Yang, Claudia Verderio, Eva‐Maria Krämer‐Albers, Tsuneya Ikezu

Mitochondrial extracellular vesicles, autoimmunity and myocarditis

Frontiers in Immunology(2024)10.3389/fimmu.2024.1374796

N/A

0DataRank · unranked

19 citations

Danielle J. Beetler, Elizabeth J McCabe, Jon Sin, Tsuneya Ikezu, DeLisa Fairweather +1 more

Amyloid precursor protein and presenilin‐1 knock‐in immunodeficient mice exhibit intraneuronal Aβ pathology, microgliosis, and extensive neuronal loss

Alzheimer s & Dementia(2025)10.1002/alz.70084

N/A

0DataRank · unranked

12 citations

Jatin Machhi, Emma G. Foster, Rana Kadry, Shaurav Bhattarai, Yaman Lu +9 more

Recommendations for Studying In Situ Extracellular Vesicles From Solid Tissue

Journal of Extracellular Vesicles(2025)10.1002/jev2.70185

N/A

0DataRank · unranked

7 citations

Yiyao Huang, An Hendrix, Andrew F. Hill, Stephanie N. Hurwitz, Tsuneya Ikezu +5 more

Development and characterization of in vitro inducible immortalization of a murine microglia cell line for high throughput studies

Scientific Reports(2025)10.1038/s41598-025-87543-1

N/A

0DataRank · unranked

2 citations

Matthew A. de Cruz, Yang You, Seiko Ikezu, Tsuneya Ikezu, Hana Yeh

Rapid and high-yield recovery of plasma-derived extracellular vesicles using modified chromatography with soluble protein depletion for biomarker discovery

Cell Communication and Signaling(2025)10.1186/s12964-025-02263-3

N/A

0DataRank · unranked

1 citations

Zhengrong Zhang, Samuel Cortes, Son Nguyen, Prakruthi Vadakattu, Bridgette Melvin +8 more

P2RX7 regulates tauopathy progression via tau and mitochondria loading in extracellular vesicles

Research Square(2025)10.21203/rs.3.rs-6771517/v1

N/A

0DataRank · unranked

2 citations

Victor Bodart‐Santos, Arun Reddy Ravula, Yang You, M. F. L. Abdullah, Zhi Ruan +15 more

Proteomic characterization of neuronal extracellular vesicle interactomes in Alzheimer’s disease mouse model through TurboID-based proximity labeling

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.22.684016

N/A

0DataRank · unranked

0 citations

Yunfei Chen, M. F. L. Abdullah, S. Nguyen, James McQuaker-Kajiwara, Bridgette Melvin +6 more

Proteomic Profiling of Extracellular Vesicles Derived from Cerebrospinal Fluid of Alzheimer’s Disease Patients: A Pilot Study

Cells(2020)10.3390/cells9091959

N/A

0DataRank · unranked

191 citations

Mark P. Jedrychowski, Kiran Yanamandra, Seiko Ikezu, Steven P. Gygi, Tsuneya Ikezu +1 more

P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice

Molecular Neurodegeneration(2020)10.1186/s13024-020-00396-2

N/A

0DataRank · unranked

156 citations

Jean-Christophe Delpech, Srinidhi Venkatesan Kalavai, Alicia A. Van Enoo, Jianqiao Hu, Seiko Ikezu +2 more

Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons

Brain(2020)10.1093/brain/awaa376

N/A

0DataRank · unranked

281 citations

Dhruba Pathak, Srinidhi Venkatesan Kalavai, Asuka Yoshii-Kitahara, Satoshi Muraoka, Nemil Bhatt +12 more

Tsuneya Ikezu

Indexed papers

Top data-sharing exemplar

Papers