William L. Jorgensen

Arts and HumanitiesPhysics and AstronomyBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 23 papers. Top paper: “Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations”.

Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations

ACS Central Science(2021)10.1021/acscentsci.1c00039

N/A

0.834DataRank · unranked

259 citations

Elizabeth A. Stone, M.G. Deshmukh, Joseph A. Ippolito, Mohammad Mehdi Ghahremanpour, Julian Tirado‐Rives +11 more

A High-Throughput, High-Containment Human Primary Epithelial Airway Organ-on-Chip Platform for SARS-CoV-2 Therapeutic Screening

Cells(2023)10.3390/cells12222639

N/A

0.470DataRank · unranked

22 citations

Felix Mba Medie, Rebeccah J. Luu, Robert B. Gaibler, Thomas J. Mulhern, Caitlin R. Miller +14 more

Proof-of-concept studies with a computationally designed M pro inhibitor as a synergistic combination regimen alternative to Paxlovid

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2320713121

N/A

0.425DataRank · unranked

16 citations

Irfan Ullah, Amalendu P. Ranjan, Shuo Zhang, Qihao Wu, Krasimir A. Spasov +9 more

Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa: Virtual screening identifies novel TS allosteric inhibitors

Bioorganic & Medicinal Chemistry Letters(2020)10.1016/j.bmcl.2020.127292

N/A

0DataRank · unranked

3 citations

Daniel J. Czyzyk, Vidya P. Kumar, William L. Jorgensen, Karen S. Anderson, Victor G. Ruiz

Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.28.271957

N/A

0DataRank · unranked

29 citations

Julian Tirado‐Rives, M.G. Deshmukh, Joseph A. Ippolito, Chunhui Zhang, Israel Cabeza de Vaca +4 more

Structure-guided design of a perampanel-derived pharmacophore targeting the SARS-CoV-2 main protease

Structure(2021)10.1016/j.str.2021.06.002

N/A

0DataRank · unranked

63 citations

Joseph A. Ippolito, Chunhui Zhang, Elizabeth A. Stone, R. Reilly, Scott J. Miller +3 more

Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency

ACS Medicinal Chemistry Letters(2021)10.1021/acsmedchemlett.1c00326

N/A

0DataRank · unranked

57 citations

Krasimir A. Spasov, R. Reilly, Klarissa Hollander, Elizabeth A. Stone, Joseph A. Ippolito +11 more

Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead

ACS Medicinal Chemistry Letters(2021)10.1021/acsmedchemlett.0c00612

N/A

0DataRank · unranked

28 citations

Haichan Niu, Nicole Bertoletti, Zachary J. Carter, Shengyan Jin, Krasimir A. Spasov +6 more

Indoloxytriazines as binding molecules for the JAK2 JH2 pseudokinase domain and its V617F variant

Tetrahedron Letters(2021)10.1016/j.tetlet.2021.153248

N/A

0DataRank · unranked

12 citations

Maria-Elena Liosi, Sean P. Henry, Luca Deiana, John C. Faver, S.G. Krimmer +4 more

Insights on JAK2 Modulation by Potent, Selective, and Cell-Permeable Pseudokinase-Domain Ligands

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00283

N/A

0DataRank · unranked

22 citations

Joseph A. Ippolito, Sean P. Henry, S.G. Krimmer, Ana S. Newton, Kara J. Cutrona +5 more

Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase

Frontiers in Molecular Biosciences(2022)10.3389/fmolb.2022.805187

N/A

0DataRank · unranked

11 citations

Nicole Bertoletti, Albert H. Chan, Joseph A. Ippolito, Mariela Bollini, Krasimir A. Spasov +3 more

Covalent and noncovalent strategies for targeting Lys102 in HIV-1 reverse transcriptase

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115894

N/A

0DataRank · unranked

9 citations

Sean Henry, Klarissa Hollander, Zachary J. Carter, Krasimir A. Spasov, William L. Jorgensen +2 more

Design, synthesis, and biological testing of biphenylmethyloxazole inhibitors targeting HIV-1 reverse transcriptase

Bioorganic & Medicinal Chemistry Letters(2023)10.1016/j.bmcl.2023.129216

N/A

0DataRank · unranked

6 citations

Klarissa Hollander, Krasimir A. Spasov, Karen S. Anderson, William L. Jorgensen, Zachary J. Carter

Exploring novel HIV‐1 reverse transcriptase inhibitors with drug‐resistant mutants: A double mutant surprise

Protein Science(2023)10.1002/pro.4814

N/A

0DataRank · unranked

6 citations

Albert H. Chan, Kathleen M. Frey, Olivia Hunker, Joseph A. Ippolito, Krasimir A. Spasov +5 more

Monte Carlo simulations for free energies of hydration: Past to present

The Journal of Chemical Physics(2024)10.1063/5.0222659

N/A

0DataRank · unranked

11 citations

William L. Jorgensen

Enthalpies and entropies of hydration from Monte Carlo simulations

Physical Chemistry Chemical Physics(2024)10.1039/d4cp00297k

N/A

0DataRank · unranked

4 citations

William L. Jorgensen

Prodrug nanotherapy demonstrates in vivo anticryptosporidial efficacy in a mouse model of chronic Cryptosporidium infection

RSC Pharmaceutics(2024)10.1039/d4pm00093e

N/A

0DataRank · unranked

1 citations

Daniel J. Czyzyk, Griselle Martinez-Traverso, Aygül Sadıqova, Margarita Valhondo, Deborah A. Schaefer +7 more

Exploring Possible Drug-Resistant Variants of SARS-CoV-2 Main Protease (Mpro) with Noncovalent Preclinical Candidate, Mpro61

ACS Bio & Med Chem Au(2025)10.1021/acsbiomedchemau.4c00109

N/A

0DataRank · unranked

1 citations

Christina Papini, Su Tang, Kathy Huynh, Chunhui Zhang, William L. Jorgensen +2 more

Free Energies of Solvation in Benzene and Hexafluorobenzene: Is Explicit Polarization Needed?

The Journal of Physical Chemistry B(2025)10.1021/acs.jpcb.5c02405

N/A

0DataRank · unranked

1 citations

Julian Tirado‐Rives, William L. Jorgensen

Structure-Guided Identification of DNMT3B Inhibitors

ACS Medicinal Chemistry Letters(2020)10.1021/acsmedchemlett.0c00011

N/A

0DataRank · unranked

20 citations

John C. Faver, Goran Micevic, Viswanathan Muthusamy, Shalley N. Kudalkar, Nicole Bertoletti +4 more

Mechanistic basis for a novel dual-function Gag-Pol dimerizer potentiating CARD8 inflammasome activation and clearance of HIV-infected cells

npj Drug Discovery.(2025)10.1038/s44386-025-00025-2

N/A

0DataRank · unranked

0 citations

Swapnil C. Devarkar, Su Tang, Ritudhwaj Tiwari, Shumeng Ma, Won‐Gil Lee +10 more

Structural investigation of 2‐naphthyl phenyl ether inhibitors bound to WT and Y181C reverse transcriptase highlights key features of the NNRTI binding site

Protein Science(2020)10.1002/pro.3910

N/A

0DataRank · unranked

12 citations

Joseph A. Ippolito, Albert H. Chan, Won‐Gil Lee, Krasimir A. Spasov, William L. Jorgensen +2 more

Selective Janus Kinase 2 (JAK2) Pseudokinase Ligands with a Diaminotriazole Core

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00192

N/A

0DataRank · unranked

26 citations

S.G. Krimmer, Ana S. Newton, Thomas K. Dawson, D.E. Puleo, Kara J. Cutrona +4 more