Peter Arvan

Also affiliated with Johnson City Medical Center

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 57 papers. Top paper: “Dominant‐Negative Behavior of Mammalian Vps35 in Yeast Requires a Conserved PRLYL Motif Involved in Retromer Assembly”.

Dominant‐Negative Behavior of Mammalian Vps35 in Yeast Requires a Conserved PRLYL Motif Involved in Retromer Assembly

Traffic(2007)10.1111/j.1600-0854.2007.00658.x

N/A

1.8DataRank · unranked

33 citations

Steven Nothwehr, Roberto Lara‐Lemus, Bao‐yan Zhang, Harald Peter, Peter Arvan +1 more

Competitive Inhibition of the Endoplasmic Reticulum Signal Peptidase by Non-cleavable Mutant Preprotein Cargos

Journal of Biological Chemistry(2015)10.1074/jbc.m115.692350

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1.3DataRank · unranked

31 citations

Wei Chen, Jinhong Sun, Huan Guo, Rachel Madley, Yi Xiong +7 more

Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity

Diabetes(2022)10.2337/db21-0989

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0.716DataRank · unranked

25 citations

Seán Connolly, Renelle J. Gee, TuKiet T. Lam, Jean Kanyo, Jian Peng +13 more

“Register-shift” insulin analogs uncover constraints of proteotoxicity in protein evolution

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.011389

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0.494DataRank · unranked

15 citations

Ming Liu, Balamurugan Dhayalan, Yen‐Shan Chen, Nicholas A. Smith, Leili Rahimi +11 more

The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum

Diabetes(2021)10.2337/db21-0638

N/A

0.485DataRank · unranked

14 citations

Yumeng Huang, Xin Li, Peter Arvan, Ming Liu, Xiaoxi Xu

Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes

Diabetes(2021)10.2337/db21-0422

N/A

0.464DataRank · unranked

13 citations

Anoop Arunagiri, Leena Haataja, Mauricio Torres, Dennis Larkin, John W. Kappler +3 more

Discovery of a Redox Thiol Switch: Implications for Cellular Energy Metabolism

Molecular & Cellular Proteomics(2020)10.1074/mcp.ra119.001910

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0DataRank · unranked

46 citations

Ling Li, Marc Parisien, Jing Wu, Ilya Bederman, Zhaofeng Gao +10 more

The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis

Molecular Metabolism(2020)10.1016/j.molmet.2020.101015

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0DataRank · unranked

32 citations

Elizabeth Haythorne, Alejandra Tomás, Leena Haataja, Andreas Müller, Peter Arvan +26 more

Role of Proinsulin Self-Association in Mutant INS Gene–Induced Diabetes of Youth

Diabetes(2020)10.2337/db19-1106

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0DataRank · unranked

31 citations

Yi Xiong, Xin Li, Leena Haataja, Wei Chen, Saiful A. Mir +14 more

Reticulon protects the integrity of the ER membrane during ER escape of large macromolecular protein complexes

The Journal of Cell Biology(2020)10.1083/jcb.201908182

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0DataRank · unranked

27 citations

Jeffrey M. Williams, Peter Arvan, Billy Tsai, Yujie Chen

Epitope-tagging of the endogenous murine BiP/GRP78/ Hspa5 locus allows direct analysis of the BiP interactome and protein misfolding in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.01.892539

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0DataRank · unranked

2 citations

Zhouji Chen, Insook Jang, Peter Arvan, Randal J. Kaufman, Yunqian Peng

The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.25.007286

N/A

0DataRank · unranked

0 citations

Elizabeth Haythorne, Alejandra Tomás, Leena Haataja, Andreas Müller, Peter Arvan +26 more

In vivo imaging of individual islets across the mouse pancreas reveals a heterogeneous insulin secretion response to glucose

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.22.111336

N/A

0DataRank · unranked

0 citations

Peter Arvan, Randy J. Seeley, Corentin Cras‐Méneur, Henriette Frikke‐Schmidt

Normal and defective pathways in biogenesis and maintenance of the insulin storage pool

Journal of Clinical Investigation(2021)10.1172/jci142240

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0DataRank · unranked

68 citations

Yumeng Huang, Xiaoxi Xu, Xin Li, Maroof Alam, Anoop Arunagiri +9 more

PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones

Nature Communications(2021)10.1038/s41467-021-26225-8

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0DataRank · unranked

51 citations

Jeffrey Knupp, Anoop Arunagiri, Leena Haataja, Peter Arvan, Billy Tsai +1 more

Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft size

JCI Insight(2021)10.1172/jci.insight.141553

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0DataRank · unranked

43 citations

Yurong Xin, Qian Du, Daniela Georgieva, Giacomo Diedenhofen, Leena Haataja +15 more

Distinct states of proinsulin misfolding in MIDY

Cellular and Molecular Life Sciences(2021)10.1007/s00018-021-03871-1

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0DataRank · unranked

34 citations

Anoop Arunagiri, Anis Hassan, Kaitlin Regan, Billy Tsai, Balamurugan Dhayalan +4 more

The structure of natively iodinated bovine thyroglobulin

Acta Crystallographica Section D Structural Biology(2021)10.1107/s2059798321010056

N/A

0DataRank · unranked

25 citations

Mykhailo Kopylov, Daija Bobe, Kotaro Kelley, Edward T. Eng, Peter Arvan +2 more

Deficient endoplasmic reticulum translocon‐associated protein complex limits the biosynthesis of proinsulin and insulin

The FASEB Journal(2021)10.1096/fj.202002774r

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0DataRank · unranked

24 citations

Xiaoxi Xu, Peter Arvan, Ming Liu, Yumeng Huang

Thyroid hormone synthesis continues despite biallelic thyroglobulin mutation with cell death

JCI Insight(2021)10.1172/jci.insight.148496

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0DataRank · unranked

18 citations

Aaron P. Kellogg, Cintia E. Citterio, Hao Zhang, Dennis Larkin, Yoshiaki Morishita +4 more

Cell death–associated lipid droplet protein CIDE-A is a noncanonical marker of endoplasmic reticulum stress

JCI Insight(2021)10.1172/jci.insight.143980

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0DataRank · unranked

10 citations

Aaron P. Kellogg, Dennis Larkin, Wei Chen, Suryakiran Vadrevu, Leslie S. Satin +3 more

Improved in vivo imaging method for individual islets across the mouse pancreas reveals a heterogeneous insulin secretion response to glucose

Scientific Reports(2021)10.1038/s41598-020-79727-8

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0DataRank · unranked

9 citations

Peter Arvan, Randy J. Seeley, Corentin Cras‐Méneur, Henriette Frikke‐Schmidt

The ER transmembrane protein PGRMC1 recruits misfolded proteins for reticulophagic clearance

Autophagy(2021)10.1080/15548627.2021.1997062

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0DataRank · unranked

8 citations

Yu-Jie Chen, Anoop Arunagiri, Leena Haataja, Peter Arvan, Billy Tsai +1 more

Distinct states of proinsulin misfolding in MIDY

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.10.442447

N/A

0DataRank · unranked

0 citations

Anoop Arunagiri, Anis Hassan, Kaitlin Regan, Billy Tsai, Balamurugan Dhayalan +4 more

Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.01.446633

N/A

0DataRank · unranked

0 citations

Anoop Arunagiri, Leena Haataja, Mauricio Torres, Dennis Larkin, John W. Kappler +3 more

Integration of ER protein quality control mechanisms defines β cell function and ER architecture

Journal of Clinical Investigation(2022)10.1172/jci163584

N/A

0DataRank · unranked

49 citations

Mauricio Torres, Jason Zhang, You Lu, Leena Haataja, Rachel B. Reinert +8 more

IER3IP1 is critical for maintaining glucose homeostasis through regulating the endoplasmic reticulum function and survival of β cells

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2204443119

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0DataRank · unranked

20 citations

Jinyang Zhen, Wenli Feng, Zhenqian Fan, Li Ding, Xiaoyun Yang +14 more

Inflammatory Cytokines Rewire the Proinsulin Interaction Network in Human Islets

The Journal of Clinical Endocrinology & Metabolism(2022)10.1210/clinem/dgac493

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0DataRank · unranked

16 citations

Anita Pottekat, Kouta Lee, Megha Raghunathan, Salvatore Loguercio, Saiful A. Mir +6 more

Maintaining the thyroid gland in mutant thyroglobulin–induced hypothyroidism requires thyroid cell proliferation that must continue in adulthood

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102066

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0DataRank · unranked

9 citations

Bhoomanyu Malik, Crystal Young, Hao Zhang, Dennis Larkin, Xiao-Hui Liao +4 more

Thyroidal Transcriptomic Profiles of Pathoadaptive Responses to Congenital Hypothyroidism in XB130 Knockout Mice

Cells(2022)10.3390/cells11060975

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0DataRank · unranked

8 citations

Aaron Wong, Hiroki Shimizu, Jinbo Zhao, Hae-Ra Cho, Yingchun Wang +4 more

Transgenic overexpression of microRNA-30d in pancreatic beta-cells progressively regulates beta-cell function and identity

Scientific Reports(2022)10.1038/s41598-022-16174-7

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0DataRank · unranked

8 citations

Jacob Schoenborn, Zhihong Wang, Xinqian Chen, Katy Matson, Ramkumar Mohan +6 more

Proteasomal degradation of WT proinsulin in pancreatic beta cells

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102406

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0DataRank · unranked

7 citations

Anoop Arunagiri, Leena Haataja, Maroof Alam, Shuhui Ji, Ling Qi +4 more

Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.02.502357

N/A

0DataRank · unranked

4 citations

Emily M. Walker, Nathan Lawlor, Anne Lietzke, Vaibhav Sidarala, Jie Zhu +24 more

Inflammatory cytokines rewire the proinsulin interaction network in human islets

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.07.487532

N/A

0DataRank · unranked

0 citations

Anita Pottekat, Kouta Lee, Megha Raghunathan, Salvatore Loguercio, Saiful A. Mir +6 more

Differential roles of beta-cell IP3R and RyR ER Ca 2+ channels in ER stress-induced alterations of beta-cell Ca 2+ homeostasis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.11.511769

N/A

0DataRank · unranked

0 citations

Andrea Hermann, Juan Leon, Anoop Arunagiri, Peter Arvan, Leslie S. Satin +1 more

ER stress increases expression of intracellular calcium channel RyR1 to modify Ca2+ homeostasis in pancreatic beta cells

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105065

N/A

0DataRank · unranked

26 citations

Andrea Herrmann, Juan Leon, Sivakumar Jeyarajan, Anoop Arunagiri, Peter Arvan +3 more

Autophagy of the ER: the secretome finds the lysosome

FEBS Journal(2023)10.1111/febs.16986

N/A

0DataRank · unranked

21 citations

Madison Pletan, Peter Arvan, Billy Tsai, Jeffrey Knupp

Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction

Nature Communications(2023)10.1038/s41467-023-39978-1

N/A

0DataRank · unranked

16 citations

Chandan Sona, Xin Yan, Yunxiao Li, Adrija Pathak, Mark I. McDermott +17 more

Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland

JCI Insight(2023)10.1172/jci.insight.169937

N/A

0DataRank · unranked

11 citations

Crystal Young, Xiao-Hui Liao, Samuel Refetoff, Mauricio Torres, Yaron Tomer +7 more

Nutrient-dependent regulation of β-cell proinsulin content

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104836

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0DataRank · unranked

6 citations

Anoop Arunagiri, Maroof Alam, Leena Haataja, Charles R. Evans, Ivy Yan Zhao +8 more

Permanent Neonatal diabetes-causing Insulin mutations have dominant negative effects on beta cell identity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.01.555839

N/A

0DataRank · unranked

1 citations

Lina Sui, Qian Du, Leena Haataja, Yishu Yin, Ryan Viola +7 more

Sigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy

Cell Reports(2024)10.1016/j.celrep.2024.114619

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0DataRank · unranked

13 citations

Yujie Chen, Emily Wang, Peter Arvan, Billy Tsai, Jeffrey Knupp

Permanent neonatal diabetes-causing insulin mutations have dominant negative effects on beta cell identity

Molecular Metabolism(2024)10.1016/j.molmet.2024.101879

N/A

0DataRank · unranked

14 citations

Lina Sui, Qian Du, Leena Haataja, Yishu Yin, Ryan Viola +7 more

Role of Sec61α2 Translocon in Insulin Biosynthesis

Diabetes(2024)10.2337/db24-0115

N/A

0DataRank · unranked

6 citations

Thomas W. Bell, Truc Le, Ivy Yan Zhao, Emily M. Walker, Yiqin Wang +8 more

Untangling the genetics of beta cell dysfunction and death in type 1 diabetes

Molecular Metabolism(2024)10.1016/j.molmet.2024.101973

N/A

0DataRank · unranked

5 citations

Ruth M. Elgamal, Belle A. Henry-Kanarek, Peter Arvan, Shuibing Chen, Sangeeta Dhawan +7 more

SIGMAR1/Sigma-1 receptor: a key regulator in stabilizing and translating LC3B mRNA for autophagosome formation

Autophagy(2024)10.1080/15548627.2024.2413313

N/A

0DataRank · unranked

3 citations

Jeffrey Knupp, Emily Wang, Peter Arvan, Billy Tsai, Yu-Jie Chen

Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues

Science(2025)10.1126/science.adf2034

N/A

0DataRank · unranked

61 citations

Gemma L. Pearson, Nathan Lawlor, Ava M. Stendahl, Anne Lietzke, Vaibhav Sidarala +25 more

Small-Molecule FICD Inhibitors Suppress Endogenous and Pathologic FICD-Mediated Protein AMPylation

ACS Chemical Biology(2025)10.1021/acschembio.4c00847

N/A

0DataRank · unranked

5 citations

Muhammad Mansoor Alam, Arghya Chakravorty, Shannon M. Lacy, William Giblin, Jason C. Rech +4 more

An Essential Role of IER3IP1 in β-Cell Development and Proinsulin Trafficking

Diabetes(2025)10.2337/dbi24-0045

N/A

0DataRank · unranked

1 citations

Peter Arvan, Ming Liu, Wenli Feng

A Genetically-Engineered Thyroid Gland Built for Selective Triiodothyronine Secretion

International Journal of Molecular Sciences(2025)10.3390/ijms26157166

N/A

0DataRank · unranked

1 citations

Berenice Morales-Rodriguez, Xiao-Hui Liao, Catherine N. Vu, Rachel Nguyen, Jessie Tsai +7 more

A new form of diabetes caused by INS mutations defined by zygosity, stem cell and population data

EMBO Molecular Medicine(2026)10.1038/s44321-025-00362-9

N/A

0DataRank · unranked

0 citations

Marianne Becker, Ulrike Schierloh, Flávia Natividade da Silva, Leena Haataja, Ying Cai +27 more

Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis

Journal of Clinical Investigation(2025)10.1172/jci187341

N/A

0DataRank · unranked

0 citations

Leena Haataja, Maroof Alam, Noah Gleason, Emma Mastroianni, Chen Cheng +10 more

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

Nature Communications(2020)10.1038/s41467-020-17718-z

N/A

0DataRank · unranked

141 citations

Ben Brumpton, Ömer Kabil, Jūlı́us Guðmundsson, Guðmar Þorleifsson, Joshua S. Weinstock +51 more

Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling

Journal of Clinical Investigation(2020)10.1172/jci134874

N/A

0DataRank · unranked

89 citations

Tongyu Liu, Yewei Ji, Rachel B. Reinert, Mauricio Torres, Xin Li +11 more

Evolution of insulin at the edge of foldability and its medical implications

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2010908117

N/A

0DataRank · unranked

39 citations

Ming Liu, Yanwu Yang, Balamurugan Dhayalan, Nalinda P. Wickramasinghe, Yen‐Shan Chen +9 more

Biological behaviors of mutant proinsulin contribute to the phenotypic spectrum of diabetes associated with insulin gene mutations

Molecular and Cellular Endocrinology(2020)10.1016/j.mce.2020.111025

N/A

0DataRank · unranked

18 citations

Cécile Saint‐Martin, Jialu Xu, Li Ding, Ruodan Wang, Wenli Feng +9 more

p.L571P in the linker domain of rat thyroglobulin causes intracellular retention

Molecular and Cellular Endocrinology(2020)10.1016/j.mce.2020.110719

N/A

0DataRank · unranked

8 citations

Sofía Siffo, Christian M. Moya, Mauricio Gomes Pio, Maricel F. Molina, Karen G. Scheps +5 more