Frances H. Arnold

Also affiliated with Division of Chemistry

Earth and Planetary SciencesBiochemistry, Genetics and Molecular BiologyChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 44 papers. Top paper: “In vivo hypermutation and continuous evolution”.

In vivo hypermutation and continuous evolution

Nature Reviews Methods Primers(2022)10.1038/s43586-022-00130-w

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0.612DataRank · unranked

58 citations

Gordon Rix, Amanuella A. Mengiste, Beatriz Álvarez, Daeje Seo, Haiqi Chen +16 more

New-to-nature chemistry from old protein machinery: carbene and nitrene transferases

Current Opinion in Biotechnology(2020)10.1016/j.copbio.2020.12.005

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0DataRank · unranked

112 citations

Frances H. Arnold, Zhen Liu

Scalable, continuous evolution for the generation of diverse enzyme variants encompassing promiscuous activities

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.01.128165

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0DataRank · unranked

14 citations

Ella J. Watkins‐Dulaney, Patrick J. Almhjell, Christina Smith, Frances H. Arnold, Chang C. Liu +1 more

Selective Enzymatic Oxidation of Silanes to Silanols

ChemRxiv(2020)10.26434/chemrxiv.11996379.v1

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0DataRank · unranked

1 citations

Sabine Brinkmann‐Chen, Marc Garcia‐Borràs, John M. Roberts, Dimitris E. Katsoulis, K. N. Houk +2 more

Selective Enzymatic Oxidation of Silanes to Silanols

ChemRxiv(2020)10.26434/chemrxiv.11996379

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0DataRank · unranked

1 citations

Sabine Brinkmann‐Chen, Marc Garcia‐Borràs, John M. Roberts, Dimitris E. Katsoulis, K. N. Houk +2 more

A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo

UNC Libraries(2020)10.17615/4akg-nr71

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0DataRank · unranked

0 citations

Frances H. Arnold, Maraia E. Ener, Eric M. Brustad, Z Jane Wang, Stefanie A. Baril +2 more

Biocatalytic, Intermolecular C−H Bond Functionalization for the Synthesis of Enantioenriched Amides

Angewandte Chemie International Edition(2021)10.1002/anie.202110873

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0DataRank · unranked

67 citations

Shilong Gao, Zhen Liu, Sharath Chandra Mallojjala, Jennifer S. Hirschi, Frances H. Arnold +1 more

Biocatalytic One-Carbon Ring Expansion of Aziridines to Azetidines via a Highly Enantioselective [1,2]-Stevens Rearrangement

ChemRxiv(2021)10.26434/chemrxiv-2021-8fq9b

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0DataRank · unranked

4 citations

Ravi Lal, Luca Marchetti, Frances H. Arnold, David C. Miller

Origin and Control of Chemoselectivity in Cytochrome c-Catalyzed Carbene Transfer into Si–H and N–H bonds

ChemRxiv(2021)10.26434/chemrxiv.14102363.v1

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0DataRank · unranked

3 citations

S. B. Jennifer Kan, Russell D. Lewis, Allison Tang, Gonzalo Jiménez‐Osés, Frances H. Arnold +2 more

Biocatalytic One-Carbon Ring Expansion of Aziridines to Azetidines via a Highly Enantioselective [1,2]-Stevens Rearrangement

Figshare(2021)10.33774/chemrxiv-2021-8fq9b-v2

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0DataRank · unranked

0 citations

Ravi Lal, Luca Marchetti, Frances H. Arnold, David C. Miller

Biocatalytic One-Carbon Ring Expansion of Aziridines to Azetidines via a Highly Enantioselective [1,2]-Stevens Rearrangement

ChemRxiv(2021)10.26434/chemrxiv-2021-8fq9b-v2

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0DataRank · unranked

0 citations

Ravi Lal, Luca Marchetti, Frances H. Arnold, David C. Miller

Biocatalytic One-Carbon Ring Expansion of Aziridines to Azetidines via a Highly Enantioselective [1,2]-Stevens Rearrangement

(2021)10.33774/chemrxiv-2021-8fq9b

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0DataRank · unranked

0 citations

Ravi Lal, Luca Marchetti, Frances H. Arnold, David C. Miller

Origin and Control of Chemoselectivity in Cytochrome c-Catalyzed Carbene Transfer into Si–H and N–H bonds

ChemRxiv(2021)10.26434/chemrxiv.14102363

N/A

0DataRank · unranked

0 citations

S. B. Jennifer Kan, Russell D. Lewis, Allison Tang, Gonzalo Jiménez‐Osés, Frances H. Arnold +2 more

In vivo hypermutation and continuous evolution

Nature Reviews Methods Primers(2022)10.1038/s43586-022-00119-5

N/A

0DataRank · unranked

141 citations

Gordon Rix, Amanuella A. Mengiste, Beatriz Álvarez, Daeje Seo, Haiqi Chen +16 more

Enzymatic Nitrogen Insertion into Unactivated C–H Bonds

Journal of the American Chemical Society(2022)10.1021/jacs.2c08285

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0DataRank · unranked

89 citations

Shilong Gao, Anuvab Das, Sharath Chandra Mallojjala, Edwin Alfonzo, Yueming Long +3 more

Biocatalytic One-Carbon Ring Expansion of Aziridines to Azetidines via a Highly Enantioselective [1,2]-Stevens Rearrangement

Journal of the American Chemical Society(2022)10.1021/jacs.2c00251

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0DataRank · unranked

82 citations

Ravi Lal, Luca Marchetti, Frances H. Arnold, David C. Miller

Biocatalytic Carbene Transfer Using Diazirines

Journal of the American Chemical Society(2022)10.1021/jacs.2c02723

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0DataRank · unranked

72 citations

Emma Danelius, Tamir Gonen, Frances H. Arnold, Nicholas J. Porter

Protoglobin‐Catalyzed Formation of cis‐Trifluoromethyl‐Substituted Cyclopropanes by Carbene Transfer

Angewandte Chemie International Edition(2022)10.1002/anie.202208936

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0DataRank · unranked

51 citations

Anuvab Das, Anders M. Knight, Gonzalo Jiménez‐Osés, K. N. Houk, Marc Garcia‐Borràs +3 more

New additions to the arsenal of biocatalysts for noncanonical amino acid synthesis

Current Opinion in Green and Sustainable Chemistry(2022)10.1016/j.cogsc.2022.100701

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0DataRank · unranked

38 citations

Anuvab Das, Frances H. Arnold, Edwin Alfonzo

Protoglobin‐Catalyzed Formation of cis‐Trifluoromethyl‐Substituted Cyclopropanes by Carbene Transfer

Angewandte Chemie(2022)10.1002/ange.202208936

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0DataRank · unranked

6 citations

Anuvab Das, Anders M. Knight, Gonzalo Jiménez‐Osés, K. N. Houk, Marc Garcia‐Borràs +3 more

Enzymatic Nitrogen Insertion into Unactivated C–H Bonds

ChemRxiv(2022)10.26434/chemrxiv-2022-w8sg3

N/A

0DataRank · unranked

5 citations

Shilong Gao, Anuvab Das, Sharath Chandra Mallojjala, Edwin Alfonzo, Yueming Long +3 more

MicroED structure of a protoglobin reactive carbene intermediate

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.18.512604

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0DataRank · unranked

4 citations

Nicholas J. Porter, Johan Unge, Frances H. Arnold, Tamir Gonen, Emma Danelius

Chemodivergent C(sp3)–H and C(sp2)–H Cyanomethylation Using Engineered Carbene Transferases

ChemRxiv(2022)10.26434/chemrxiv-2022-z6pkw

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0DataRank · unranked

1 citations

Ailiena O. Maggiolo, Edwin Alfonzo, Runze Mao, Nicholas J. Porter, Nayla M. Abney +2 more

Biocatalytic Carbene Transfer Using Diazirines

ChemRxiv(2022)10.26434/chemrxiv-2022-9v4j1

N/A

0DataRank · unranked

0 citations

Emma Danelius, Tamir Gonen, Frances H. Arnold, Nicholas J. Porter

Biocatalytic One-Carbon Ring Expansion of Aziridines to Azetidines via a Highly Enantioselective [1,2]-Stevens Rearrangement

ChemRxiv(2022)10.26434/chemrxiv-2021-8fq9b-v3

N/A

0DataRank · unranked

0 citations

Ravi Lal, Luca Marchetti, Frances H. Arnold, David C. Miller

Biocatalytic One-Carbon Ring Expansion of Aziridines to Azetidines via a Highly Enantioselective [1,2]-Stevens Rearrangement

(2022)10.33774/chemrxiv-2021-8fq9b-v3

N/A

0DataRank · unranked

0 citations

Ravi Lal, Luca Marchetti, Frances H. Arnold, David C. Miller

Enzymatic Nitrogen Incorporation Using Hydroxylamine

Journal of the American Chemical Society(2023)10.1021/jacs.3c08053

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0DataRank · unranked

54 citations

Anuvab Das, Edwin Alfonzo, Kathleen M. Sicinski, D. L. RIEGER, Frances H. Arnold +1 more

Chemodivergent C(sp3)–H and C(sp2)–H cyanomethylation using engineered carbene transferases

Nature Catalysis(2023)10.1038/s41929-022-00908-x

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0DataRank · unranked

40 citations

Ailiena O. Maggiolo, Edwin Alfonzo, Runze Mao, Nicholas J. Porter, Nayla M. Abney +2 more

MicroED Structure of a Protoglobin Reactive Carbene Intermediate

Journal of the American Chemical Society(2023)10.1021/jacs.2c12004

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0DataRank · unranked

30 citations

Nicholas J. Porter, Johan Unge, Frances H. Arnold, Tamir Gonen, Emma Danelius

Enantio- and Diastereoenriched Enzymatic Synthesis of 1,2,3-Polysubstituted Cyclopropanes from (Z/E)-Trisubstituted Enol Acetates

Journal of the American Chemical Society(2023)10.1021/jacs.3c04870

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0DataRank · unranked

28 citations

Daniel J. Wackelin, Cooper S. Jamieson, Torben Rogge, Shilong Gao, Anuvab Das +4 more

Biocatalytic Construction of Chiral Pyrrolidines and Indolines via Intramolecular C(sp3)–H Amination

ACS Central Science(2023)10.1021/acscentsci.3c00516

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0DataRank · unranked

27 citations

Shilong Gao, Yike Zou, Zhen Liu, James B. Wang, K. N. Houk +2 more

Biocatalytic, stereoconvergent alkylation of (Z/E)-trisubstituted silyl enol ethers

Nature Synthesis(2023)10.1038/s44160-023-00431-2

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0DataRank · unranked

16 citations

Doris Mia Taylor, Daniel J. Wackelin, Torben Rogge, Sophia J. Wu, Kathleen M. Sicinski +3 more

Directed evolution of P411 enzymes for amination of inert C–H bonds

Methods in enzymology on CD-ROM/Methods in enzymology(2023)10.1016/bs.mie.2023.09.009

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0DataRank · unranked

3 citations

Shilong Gao, Soumitra V. Athavale, Edwin Alfonzo, Yueming Long, Frances H. Arnold +1 more

Biocatalytic, Enantioenriched Primary Amination of Tertiary C–H Bonds

ChemRxiv(2023)10.26434/chemrxiv-2023-8d2tc

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0DataRank · unranked

1 citations

Shilong Gao, Ziyang Qin, Torben Rogge, Sophia P. Wu, Zi‐Qi Li +4 more

Enantio- and Diastereoenriched Enzymatic Synthesis of 1,2,3-Polysubstituted Cyclopropanes from (Z/E)-Trisubstituted Enol Acetates

Research Square(2023)10.21203/rs.3.rs-2802333/v1

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0DataRank · unranked

0 citations

Daniel J. Wackelin, Cooper S. Jamieson, Torben Rogge, Shilong Gao, Anuvab Das +4 more

PCAST: Report to the President and to Congress on the Seventh Assessment of the National Nanotechnology Initiative

OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)(2023)10.2172/2482287

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0DataRank · unranked

0 citations

Frances H. Arnold, White House Office of Science and Technology Policy (OSTP), Washington, DC (United States), Arati Prabhakar, Maria Zuber, Dan Arvizu +27 more

Catalyzing the future: recent advances in chemical synthesis using enzymes

Current Opinion in Chemical Biology(2024)10.1016/j.cbpa.2024.102536

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0DataRank · unranked

76 citations

Kathleen M. Sicinski, Frances H. Arnold, Julia C. Reisenbauer

Biocatalytic, enantioenriched primary amination of tertiary C–H bonds

Nature Catalysis(2024)10.1038/s41929-024-01149-w

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0DataRank · unranked

42 citations

Shilong Gao, Ziyang Qin, Torben Rogge, Sophia J. Wu, Zi‐Qi Li +4 more

The β-subunit of tryptophan synthase is a latent tyrosine synthase

Nature Chemical Biology(2024)10.1038/s41589-024-01619-z

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0DataRank · unranked

35 citations

Kadina E. Johnston, Nicholas J. Porter, Jennifer L. Kennemur, Vignesh C. Bhethanabotla, Julie Ducharme +2 more

Biocatalytic Synthesis of α-Amino Esters via Nitrene C–H Insertion

Journal of the American Chemical Society(2024)10.1021/jacs.4c09989

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0DataRank · unranked

28 citations

Deirdre Hanley, Zi‐Qi Li, Kathleen M. Sicinski, Shilong Gao, Frances H. Arnold +1 more

Enzymatic Assembly of Diverse Lactone Structures: An Intramolecular C–H Functionalization Strategy

Journal of the American Chemical Society(2024)10.1021/jacs.3c11722

N/A

0DataRank · unranked

30 citations

Runze Mao, Kathleen M. Sicinski, Yutao Zhao, Anuvab Das, Kai Chen +2 more

PCAST: Letter to the President on Expanding STEM Talent in the Federal Workforce

OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)(2024)10.2172/2481680

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0DataRank · unranked

1 citations

Frances H. Arnold, White House Office of Science and Technology Policy (OSTP), Washington, DC (United States), Arati Prabhakar, Maria Zuber, Dan Arvizu +24 more

Scalable continuous evolution for the generation of diverse enzyme variants encompassing promiscuous activities

Nature Communications(2020)10.1038/s41467-020-19539-6

N/A

0DataRank · unranked

117 citations

Ella J. Watkins‐Dulaney, Patrick J. Almhjell, Christina Smith, Frances H. Arnold, Chang C. Liu +1 more

Enzymatic Stereodivergent Synthesis of Azaspiro[2.y]alkanes

Journal of the American Chemical Society(2025)10.1021/jacs.5c07015

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0DataRank · unranked

7 citations

Yueming Long, Changhong Ko, Anuvab Das, Frances H. Arnold, Jennifer L. Kennemur