Leslie A. Lange

University of Colorado Anschutz Medical Campus

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

11.6Author DataRank

Indexed papers

9in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 9 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Nature(2021)10.1038/s41586-021-03205-y

Top 3%

7.0DataRank

Top 3%2322 citations

Daniel Harris, Michael D. Kessler, Jedidiah Carlson, Zachary A. Szpiech, Raúl Torres +95 more

Papers

Driven by 123 papers — median percentile 33. Top paper: “Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations”.

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

Cell(2020)10.1016/j.cell.2020.06.045

N/A

8.3DataRank · unranked

739 citations

Laura M. Raffield, Abdou Mousas, Saori Sakaue, Jennifer E. Huffman, Arden Moscati +95 more

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Nature(2021)10.1038/s41586-021-03205-y

Top 3%

7.0DataRank

Top 3%2322 citations

Daniel Harris, Michael D. Kessler, Jedidiah Carlson, Zachary A. Szpiech, Raúl Torres +95 more

Enhanced Statistical Tests for GWAS in Admixed Populations: Assessment using African Americans from CARe and a Breast Cancer Consortium

PLoS Genetics(2011)10.1371/journal.pgen.1001371

N/A

5.4DataRank · unranked

140 citations

Noah Zaitlen, Guillaume Lettre, Gary K. Chen, Arti Tandon, W. H. Linda Kao +40 more

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Nature Communications(2018)10.1038/s41467-018-04668-w

N/A

3.7DataRank · unranked

109 citations

Sanni Ruotsalainen, Robert E. Handsaker, Maris Alver, Jonathan M. Bloom, Timothy Poterba +442 more

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Nature Communications(2021)10.1038/s41467-021-23556-4

N/A

2.7DataRank · unranked

110 citations

Moriel Singer‐Berk, Rachel G. Son, Abigail Sveden, Jordan C. Wood, Eleina England +95 more

The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits

Cell Metabolism(2023)10.1016/j.cmet.2023.03.001

Top 8%

2.7DataRank

Top 8%136 citations

Marcin von Grotthuss, Jeffrey Massung, Dongkeun Jang, Lizz Caulkins, Ryan Koesterer +82 more

Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations

Communications Biology(2022)10.1038/s42003-022-03812-z

N/A

2.3DataRank · unranked

108 citations

Genevieve Lyons, Santiago Romero‐Brufau, Nuzulul Kurniansyah, Jennifer A. Brody, Xiuqing Guo +17 more

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

Nature Communications(2022)10.1038/s41467-022-33510-7

N/A

1.6DataRank · unranked

75 citations

Xihao Li, Zilin Li, Akhil Pampana, David Zhang, Joseph Park +95 more

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

Diabetes(2020)10.2337/db20-0070

N/A

1.5DataRank · unranked

57 citations

Yiying Zhang, Cassandra N. Spracklen, Tugce Karaderi, Lam Opal Huang, Jonathan P. Bradfield +95 more

Whole-Genome Sequencing Association Analyses of Stroke and Its Subtypes in Ancestrally Diverse Populations From Trans-Omics for Precision Medicine Project

Stroke(2021)10.1161/strokeaha.120.031792

Top 16%

1.3DataRank

Top 16%38 citations

Jeffrey W. Haessler, Regina Manansala, Kerri L. Wiggins, Arden Moscati, Alexa Beiser +34 more

Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.11.021

N/A

1.3DataRank · unranked

70 citations

Peter Dornbos, Mark Chaffin, Dajiang J. Liu, Minxian Wang, Margaret Sunitha Selvaraj +95 more

Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies

Nature Genetics(2022)10.1038/s41588-022-01225-6

N/A

1.2DataRank · unranked

63 citations

Corbin Quick, Hufeng Zhou, Sheila M. Gaynor, Yaowu Liu, Han Chen +95 more

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

Nature Communications(2021)10.1038/s41467-021-22339-1

N/A

1.1DataRank · unranked

51 citations

Akhil Pampana, Sarah E. Graham, Sanni Ruotsalainen, James A. Perry, Paul S. de Vries +95 more

The trans-ancestral genomic architecture of glycemic traits

Nature Genetics(2021)10.1038/s41588-021-00852-9

N/A

1.0DataRank · unranked

907 citations

Cassandra N. Spracklen, Gaëlle Marenne, Arushi Varshney, Laura J. Corbin, Jian’an Luan +95 more

The Polygenic and Monogenic Basis of Blood Traits and Diseases

Cell(2020)10.1016/j.cell.2020.08.008

N/A

0.988DataRank · unranked

722 citations

Erik L. Bao, Parsa Akbari, Caleb A. Lareau, Abdou Mousas, Tao Jiang +95 more

Canonical correlation analysis for multi-omics: Application to cross-cohort analysis

PLoS Genetics(2023)10.1371/journal.pgen.1010517

N/A

0.970DataRank · unranked

40 citations

François Aguet, Kristin G. Ardlie, Jiawen Chen, Elaine Cornell, Dan Cruz +22 more

Association of HLA-DRB1∗09:01 with tIgE levels among African-ancestry individuals with asthma

Journal of Allergy and Clinical Immunology(2020)10.1016/j.jaci.2020.01.011

N/A

0.853DataRank · unranked

21 citations

Sophie Limou, Michelle Daya, Wataru Morii, Nicholas Rafaels, Estelle Geffard +26 more

Association of clonal hematopoiesis with chronic obstructive pulmonary disease

Blood(2021)10.1182/blood.2021013531

N/A

0.818DataRank · unranked

232 citations

Dandi Qiao, Joselyn Rojas, Michael C. Honigberg, Adam S. Sperling, Christopher J. Gibson +39 more

The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes

Journal of Clinical Investigation(2023)10.1172/jci169608

N/A

0.788DataRank · unranked

24 citations

Nicole D. Armstrong, Michelle L. Stoller, Irina Portier, Emilia A Tugolukova, Rikki M. Tanner +17 more

Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol

Diabetes Care(2021)10.2337/dc21-1284

N/A

0.700DataRank · unranked

26 citations

Jee‐Young Moon, Iyas Daghlas, Franco Giulianini, Bianca Porneala, Fariba Ahmadizar +47 more

Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation

Human Genetics(2021)10.1007/s00439-021-02394-w

N/A

0.648DataRank · unranked

74 citations

Stephanie Yang, Christina A. Castellani, Wen Shi, Jon D. Lane, Megan L. Grove +47 more

Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke

Stroke(2020)10.1161/strokeaha.120.029123

N/A

0.637DataRank · unranked

69 citations

Hyacinth I. Hyacinth, Joshua C. Bis, Steven J. Kittner, Braxton D. Mitchell, Yu-Ching Cheng +43 more

Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci

Genome Medicine(2021)10.1186/s13073-021-00877-z

N/A

0.606DataRank · unranked

56 citations

Anna Batorsky, Mi Kyeong Lee, Mindy D Szeto, Xiaoguang Xu, Daniel L. McCartney +37 more

Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program

Communications Biology(2022)10.1038/s42003-022-03702-4

Top 34%

0.582DataRank

Top 34%16 citations

Sheila M. Gaynor, Emily M. Russell, Kenneth E. Westerman, Laura M. Raffield, Timothy D. Majarian +88 more

A large-scale multi-ethnic genome-wide association study of coronary artery disease

Research Square(2021)10.21203/rs.3.rs-275591/v1

N/A

0.561DataRank · unranked

11 citations

Catherine Tcheandjieu, Xiang Zhu, Austin T. Hilliard, Shoa L. Clarke, Valerio Napolioni +77 more

Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis

American Journal of Respiratory and Critical Care Medicine(2022)10.1164/rccm.202108-1907oc

N/A

0.546DataRank · unranked

37 citations

Tianxiao Huan, Daniel L. McCartney, Geetha Chittoor, Maaike de Vries, Lies Lahousse +57 more

Rare coding variants in 35 genes associate with circulating lipid levels – a multi-ancestry analysis of 170,000 exomes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.22.423783

N/A

0.534DataRank · unranked

11 citations

Peter Dornbos, Mark Chaffin, Dajiang J. Liu, Minxian X. Wang, Margaret Sunitha Selvaraj +95 more

Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium

EBioMedicine(2021)10.1016/j.ebiom.2020.103157

N/A

0.505DataRank · unranked

28 citations

Kelsey Grinde, Jennifer A. Brody, Charles E. Breeze, Laura M. Raffield, Josyf C. Mychaleckyj +68 more

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.08.007

N/A

0.494DataRank · unranked

26 citations

Caitlin McHugh, Linda M. Polfus, Laura M. Raffield, Meher Preethi Boorgula, Thomas W. Blackwell +88 more

Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas

Cell Genomics(2023)10.1016/j.xgen.2023.100468

N/A

0.457DataRank · unranked

20 citations

Amy R. Bentley, Charles E. Breeze, François Aguet, Xiaoguang Xu, Girish N. Nadkarni +69 more

Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data

Human Molecular Genetics(2022)10.1093/hmg/ddac117

N/A

0.455DataRank · unranked

6 citations

Julian Hecker, R. Graham Barr, Eric Boerwinkle, Brian E. Cade, Adolfo Correa +21 more

Interferon gamma-induced protein 10 (IP-10) and cardiovascular disease in African Americans

PLoS ONE(2020)10.1371/journal.pone.0231013

N/A

0.442DataRank · unranked

18 citations

Neil A. Zakai, Paul L. Auer, Mary Cushman, Ethan M. Lange, Emily B. Levitan +8 more

Investigating Gene–Diet Interactions Impacting the Association Between Macronutrient Intake and Glycemic Traits

Diabetes(2023)10.2337/db22-0851

N/A

0.425DataRank · unranked

16 citations

Maura E. Walker, Sheila M. Gaynor, Jennifer Wessel, Daniel DiCorpo, Jiantao Ma +66 more

Whole-exome sequencing study identifies four novel gene loci associated with diabetic kidney disease

Human Molecular Genetics(2022)10.1093/hmg/ddac290

N/A

0.416DataRank · unranked

15 citations

Xiao Sun, Xuenan Mi, Zhijie Huang, Y.Y. Hsu, James E. Hixson +47 more

Multiethnic Genome-Wide Association Study of Subclinical Atherosclerosis in Individuals With Type 2 Diabetes

Circulation Genomic and Precision Medicine(2021)10.1161/circgen.120.003258

N/A

0.360DataRank · unranked

10 citations

Latchezar Dimitrov, Shyh‐Huei Chen, Lawrence F. Bielak, Joshua C. Bis, Mary F. Feitosa +37 more

Whole genome sequencing association analysis of quantitative red blood cell phenotypes: the NHLBI TOPMed program

medRxiv(2020)10.1101/2020.12.09.20246736

N/A

0.360DataRank · unranked

10 citations

Adrienne M. Stilp, Caitlin McHugh, Shuquan Rao, Deepti Jain, Xiuwen Zheng +74 more

Polygenic Risk Prediction using Gradient Boosted Trees Captures Non-Linear Genetic Effects and Allele Interactions in Complex Phenotypes

medRxiv(2021)10.1101/2021.07.09.21260288

N/A

0.315DataRank · unranked

3 citations

Genevieve Lyons, Santiago Romero‐Brufau, Nuzulul Kurniansyah, Jennifer A. Brody, Xiuqing Guo +17 more

Identification of proteins associated with type 2 diabetes risk in diverse racial and ethnic populations

Diabetologia(2024)10.1007/s00125-024-06277-3

N/A

0.292DataRank · unranked

6 citations

Jingjing Zhu, Hua Zhong, Chong Wu, Haoran Xue, Burcu F. Darst +43 more

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.11.463514

N/A

0.277DataRank · unranked

3 citations

Xihao Li, Zilin Li, Akhil Pampana, David Y Zhang, Joseph Park +80 more

Alpha globin gene copy number and hypertension risk among Black Americans

PLoS ONE(2022)10.1371/journal.pone.0271031

N/A

0.257DataRank · unranked

4 citations

Neal Jeffries, Yang Yu, Orlando M. Gutiérrez, Paul Muntner, Rakhi P. Naik +10 more

Genetic underpinnings of the heterogeneous impact of obesity on lipid levels and cardiovascular disease

Genome Medicine(2025)10.1186/s13073-025-01522-9

N/A

0.241DataRank · unranked

4 citations

Heather M. Highland, Roelof A. J. Smit, Micah R. Hysong, Victoria L. Buchanan, Kristin L. Young +27 more

Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries

The Lancet Diabetes & Endocrinology(2026)10.1016/s2213-8587(25)00405-x

N/A

0.208DataRank · unranked

3 citations

Joohyun Kim, Ravi Mandla, Yingchang Lu, Ken Suzuki, Lauren E Petty +255 more

Genetic underpinnings of regional adiposity distribution in African Americans: Assessments from the Jackson Heart Study

PLoS ONE(2021)10.1371/journal.pone.0255609

N/A

0.208DataRank · unranked

3 citations

Laura M. Raffield, Leslie A. Lange, Adolfo Correa, Kira C. Taylor, Mohammad Yaser Anwar

Investigating gene-diet interactions impacting the association between macronutrient intake and glycemic traits

medRxiv(2022)10.1101/2022.07.26.22278077

N/A

0.182DataRank · unranked

1 citations

Maura E. Walker, Sheila M. Gaynor, Jennifer Wessel, Daniel DiCorpo, Jiantao Ma +66 more

Ancestry Calibration of Polygenic Risk Scores Improves Risk Stratification and Effect Estimation in African American Adults

medRxiv(2025)10.1101/2025.06.18.25329573

N/A

0.123DataRank · unranked

1 citations

Mariah Meyer, Iain R. Konigsberg, Aastha Kakar, Patrick M. Carry, Yun Li +14 more

Genome-wide Association Study of Lipid Traits in Youth With Type 2 Diabetes

Journal of the Endocrine Society(2021)10.1210/jendso/bvab139

N/A

0DataRank · unranked

3 citations

Ling Chen, Jennifer N. Todd, Jasmin Divers, Amy S. Shah, Samuel S. Gidding +9 more

Screen time behaviours may interact with obesity genes, independent of physical activity, to influence adolescent BMI in an ethnically diverse cohort

UNC Libraries(2021)10.17615/d26b-5j88

N/A

0DataRank · unranked

2 citations

M. Graff, P. Gordon-Larsen, K.M. Harris, Karen L. Mohlke, Leslie A. Lange +4 more

Evidence for Association between SH2B1 Gene Variants and Glycated Hemoglobin in Nondiabetic European American Young Adults: The Add Health Study

UNC Libraries(2021)10.17615/s0gj-1r65

N/A

0DataRank · unranked

1 citations

A.S. Richardson, Leslie A. Lange, K.E. North, K.M. Harris, Kristin L. Young +4 more

Genetic analysis of mitochondrial DNA copy number and associated traits identifies loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation, and reveals a causal association of mitochondrial function with mortality

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.25.428086

N/A

0DataRank · unranked

8 citations

Stephanie Yang, Christina A. Castellani, Wen Shi, John Lane, ML Grove +47 more

Protein prediction for trait mapping in diverse populations

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.11.455912

N/A

0DataRank · unranked

3 citations

Elyse Geoffroy, Isabelle Gregga, Ashley J. Mulford, François Aguet, Kristin G. Ardlie +27 more

HBA Copy Number and Kidney Disease Risk among Black Americans: a Longitudinal Cohort Study

medRxiv(2021)10.1101/2021.04.01.21254397

N/A

0DataRank · unranked

1 citations

Neal Jeffries, Yang Yu, Rakhi P. Naik, Amit Patki, Lydia H. Pecker +10 more

Genetic Interactions with Intrauterine Diabetes Exposure in Relation to Obesity: The EPOCH and Project Viva Studies

Pediatric Reports(2021)10.3390/pediatric13020036

N/A

0DataRank · unranked

0 citations

Elizabeth Litkowski, Ruby Fore, Sheryl L. Rifas‐Shiman, Emily Oken, Marie‐France Hivert +5 more

Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol

UNC Libraries(2021)10.17615/shbq-nv48

N/A

0DataRank · unranked

0 citations

Douglas M. Ruderfer, Goo Jun, Ji Zhang, Yun Li, Leslie A. Lange +27 more

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies

Nature Methods(2022)10.1038/s41592-022-01640-x

N/A

0DataRank · unranked

109 citations

Xihao Li, Hufeng Zhou, Sheila M. Gaynor, Margaret Sunitha Selvaraj, Theodore Arapoglou +95 more

Lung function impairment and risk of incident heart failure: the NHLBI Pooled Cohorts Study

European Heart Journal(2022)10.1093/eurheartj/ehac205

N/A

0DataRank · unranked

37 citations

Pallavi Balte, Robert Barr, Alain G. Bertoni, Surya P. Bhatt, Michael J. Cuttica +20 more

Protein prediction for trait mapping in diverse populations

PLoS ONE(2022)10.1371/journal.pone.0264341

N/A

0DataRank · unranked

30 citations

Elyse Geoffroy, Isabelle Gregga, Ashley Mulford, François Aguet, Kristin G. Ardlie +26 more

Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program

The American Journal of Human Genetics(2022)10.1016/j.ajhg.2022.03.007

N/A

0DataRank · unranked

25 citations

Dandi Qiao, Wonji Kim, Matthew Moll, Pallavi Balte, Leslie A. Lange +46 more

Significant Subgraph Detection in Multi-omics Networks for Disease Pathway Identification

Frontiers in Big Data(2022)10.3389/fdata.2022.894632

N/A

0DataRank · unranked

4 citations

Mesbah Najafi, Shahab Helmi, Katherine Pratte, Yonghua Zhuang, Weixuan Liu +5 more

Causal effects on complex traits are similar across segments of different continental ancestries within admixed individuals

Research Square(2022)10.21203/rs.3.rs-1950966/v1

N/A

0DataRank · unranked

2 citations

Yi Ding, Ziqi Xu, Yue Wu, Arjun Bhattacharya, Rachel Mester +23 more

Novel Privacy Considerations for Large Scale Proteomics

medRxiv(2022)10.1101/2022.04.06.22269907

N/A

0DataRank · unranked

0 citations

Elizabeth Litkowski, Ani Manichaikul, Leslie A. Lange, Katherine Pratte, Katerina Kechris +18 more

Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals

Nature Genetics(2023)10.1038/s41588-023-01338-6

N/A

0DataRank · unranked

126 citations

Yi Ding, Ziqi Xu, Yue Wu, Arjun Bhattacharya, Rachel Mester +24 more

Plasma neurofilament light chain concentrations are elevated in youth‐onset type 2 diabetes and associated with neuropathy

Journal of the Peripheral Nervous System(2023)10.1111/jns.12575

N/A

0DataRank · unranked

12 citations

Stefan Sillau, Alanna Ritchie, Jacob Bockhorst, Christina Coughlan, Paula Araya +9 more

Large scale proteomic studies create novel privacy considerations

Scientific Reports(2023)10.1038/s41598-023-34866-6

N/A

0DataRank · unranked

6 citations

Claire Guo, Elizabeth Litkowski, Ani Manichaikul, Bing Yu, Iain R. Konigsberg +25 more

Canonical correlation analysis for multi-omics: Application to cross-cohort analysis

UNC Libraries(2023)10.17615/hthq-e624

N/A

0DataRank · unranked

0 citations

David J. Vandenberg, J. Gustav Smith, Tamar Sofer, Yongmei Liu, Peter Durda +23 more

Lac-Phe mediates the effects of metformin on food intake and body weight

Nature Metabolism(2024)10.1038/s42255-024-00999-9

N/A

0DataRank · unranked

78 citations

Veronica L. Li, Xuchao Lyu, Xudong Chen, Wei Wei, Fahim Abbasi +22 more

A methylation risk score for chronic kidney disease: a HyperGEN study

Scientific Reports(2024)10.1038/s41598-024-68470-z

N/A

0DataRank · unranked

11 citations

Amit Patki, Vinodh Srinivasasainagendra, Bertha Hidalgo, Hemant K. Tiwari, Nita A. Limdi +29 more

Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program

UNC Libraries(2024)10.17615/75fz-j027

Top 100%

0DataRank

Top 100%0 citations

J.E. Curran, S.L.R. Kardia, Márcio Rodrigues de Almeida, J.B. Meigs, M.R. Irvin +88 more

Lung function impairment and risk of incident heart failure: the NHLBI Pooled Cohorts Study

UNC Libraries(2024)10.17615/04sy-k027

N/A

0DataRank · unranked

0 citations

DAVID R. JACOBS, Wendy White, David Couper, Joseph E. Schwartz, George O'connor +20 more

Harmonization of Respiratory Data from 9 US Population-Based Cohorts

UNC Libraries(2024)10.17615/a0zy-yy16

Top 100%

0DataRank

Top 100%0 citations

Stephanie J. London, Yunlong Zhang, R. Graham Barr, Richard F. Kaplan, P. Balte +21 more

Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease

UNC Libraries(2024)10.17615/6n4z-q211

N/A

0DataRank · unranked

0 citations

Jacob C. Ulirsch, Alex P. Reiner, Gonçalo R. Abecasis, Joshua D. Smith, Ethan M. Lange +20 more

A methylation risk score for chronic kidney disease: a HyperGEN study

UNC Libraries(2024)10.17615/54px-be07

N/A

0DataRank · unranked

0 citations

Clarissa J. Diamantidis, Leslie A. Lange, Charles P. Mouton, Bertha Hidalgo, Nora Franceschini +29 more

Alterations in DNA Methylation, Proteomic, and Metabolomic Profiles in African Ancestry Populations with APOL1 Risk Alleles

Journal of the American Society of Nephrology(2025)10.1681/asn.0000000688

N/A

0DataRank · unranked

2 citations

Ashley W. Scadden, Amarnath Marthi, Victoria L. Buchanan, Yishu Qu, Kendra Ferrier +33 more

Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals

Genome biology(2025)10.1186/s13059-025-03698-0

N/A

0DataRank · unranked

2 citations

Xihao Li, Zilin Li, Eric Van Buren, Sara Haidermota, Darina Postupaka +95 more

GLP-1R Polymorphisms Modify the Relationship Between Exposure to Gestational Diabetes Mellitus and Offspring BMI Growth: The EPOCH Study

Diabetes Care(2025)10.2337/dc25-0194

N/A

0DataRank · unranked

2 citations

Deborah H. Glueck, Leslie A. Lange, Elizabeth Litkowski, Lauren A. Vanderlinden, Iain R. Konigsberg +4 more

Quantifying Social Determinants of Health for Disease Prediction: A Multi-Level Approach Using Healthy People 2030 and All of Us Data

medRxiv(2025)10.1101/2025.09.02.25334565

N/A

0DataRank · unranked

1 citations

Alisa K. Manning, Michael D. Green, Iain R. Konigsberg, Luciana B. Vargas, Jayati Sharma +8 more

Multi-Trait Polygenic Scores for COPD and COPD Exacerbations Implicate Druggable Proteins

medRxiv(2025)10.1101/2025.08.22.25334001

N/A

0DataRank · unranked

0 citations

Iain R. Konigsberg, Yixuan He, Jingzhou Zhang, Tinashe Chikowore, William B. Feldman +22 more

Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas

UNC Libraries(2025)10.17615/yvmq-kt94

N/A

0DataRank · unranked

0 citations

Xiaoguang Xu, Jason G. Umans, Thomas Gilliland, Charles Kooperberg, Mariah Meyer +69 more

Relationships among host genetics, gut microbiota, and asthma in US Hispanic/Latino adults

Nature Communications(2025)10.1038/s41467-025-65028-z

N/A

0DataRank · unranked

0 citations

Elizabeth Litkowski, Christopher H. Arehart, Kai Luo, Niles Gilmore, Leslie A. Lange +9 more

Evaluation of height as a disease risk factor through a phenome-wide association study of genetically-predicted height

medRxiv(2021)10.1101/2021.08.29.21262793

N/A

0DataRank · unranked

2 citations

Jie Huang, Catherine Tcheandjieu, Jennifer E. Huffman, Elizabeth Litkowski, Yuk‐Lam Ho +19 more

Genetic Architecture of N-Terminal Pro-B-Type Natriuretic Peptide in a Multiancestry Study Population

Circulation: Genomic and Precision Medicine(2026)10.1161/circgen.124.005130

N/A

0DataRank · unranked

0 citations

Akhil Pampana, Mokshad Gaonkar, Amrita Nayak, Harshvir S. Bal, Nirav Patel +23 more

Genetic Risk for Hepatic Fat among an Ethnically Diverse Cohort of Youth: The Exploring Perinatal Outcomes among Children Study

The Journal of Pediatrics(2020)10.1016/j.jpeds.2020.01.031

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18 citations

Jessica R. Shaw, Elizabeth Litkowski, Ethan M. Lange, Wei Perng, Dana Dabelea +2 more

Novel genetic risk factors influence progression of islet autoimmunity to type 1 diabetes

Scientific Reports(2020)10.1038/s41598-020-75690-6

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12 citations

Umadevi Paila, Wei‐Min Chen, Aakrosh Ratan, Zhennan Zhu, Andrea K. Steck +8 more

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

Digital Commons@Becker (Washington University School of Medicine)(2020)10.17615/5y99-4w88

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0DataRank · unranked

5 citations

Terho Lehtimäki, P. Eline Slagboom, Albert V. Smith, Dennis O. Mook‐Kanamori, Paul Elliott +93 more

Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1–ADIPOQ

UNC Libraries(2020)10.17615/0pps-1042

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6 citations

Ghenadie Curocichin, Leslie A. Lange, Linda S. Adair, Thomas W. McDade, Damien C. Croteau‐Chonka +7 more

Regulatory Polymorphisms in Human DBH Affect Peripheral Gene Expression and Sympathetic Activity

UNC Libraries(2020)10.17615/sfcz-sw07

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0DataRank · unranked

3 citations

David Weinshenker, James G. Wilson, Murray H. Brilliant, Glenn S. Gerhard, Helena Kuivaniemi +12 more

Association of exome sequences with plasma C-reactive protein levels in >9000 participants

UNC Libraries(2020)10.17615/003k-2b61

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0DataRank · unranked

2 citations

Cristen J. Willer, Jennifer A. Brody, Eric Boerwinkle, Joshua C. Bis, Jeffery Haessler +27 more

Genome-wide Association with C-Reactive Protein Levels in CLHNS: Evidence for the CRP and HNF1A Loci and their Interaction with Exposure to a Pathogenic Environment

UNC Libraries(2020)10.17615/2gye-7151

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0DataRank · unranked

2 citations

Linda S. Adair, Thomas W. McDade, Ying Wu, Yun Li, Karen L. Mohlke +3 more

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

medRxiv(2020)10.1101/2020.09.22.20195529

N/A

0DataRank · unranked

11 citations

Moriel Singer‐Berk, Rachel G. Son, Abigail Sveden, Jordan C. Wood, Eleina England +95 more

Presence and Transmission of Mitochondrial Heteroplasmic Mutations in Human Populations of European and African Ancestry

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.13.337071

N/A

0DataRank · unranked

2 citations

Jessica L. Fetterman, Yong Qian, Xianbang Sun, Kaiyu Yan, Thomas W. Blackwell +15 more

Replication of LIN28B SNP association with age of menarche in young Filipino women: LIN28Bassociation with age of menarche

UNC Libraries(2020)10.17615/fj4d-fb90

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0DataRank · unranked

0 citations

D. C. Croteau‐Chonka, Karen L. Mohlke, Leslie A. Lange, L. S. Adair, N. R. Lee

find-tfbs: a tool to identify functional non-coding variants associated with complex human traits using open chromatin maps and phased whole-genome sequences

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.23.394296

N/A

0DataRank · unranked

0 citations

Florian Thibord, Paul L. Auer, John Blangero, Zeynep Coban‐Akdemir, James S. Floyd +11 more

Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity

(2020)10.2337/figshare.12933737.v1

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0DataRank · unranked

0 citations

Hanieh Yaghootkar, Yiying Zhang, Cassandra N. Spracklen, Tugce Karaderi, Lam Opal Huang +95 more

Genetic polymorphisms inCYP17,CYP3A4,CYP19A1,SRD5A2,IGF-1, andIGFBP-3 and prostate cancer risk in African-American men: The Flint Men's Health Study

UNC Libraries(2020)10.17615/r1jz-3p88

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0DataRank · unranked

0 citations

Yunfei Wang, Leslie A. Lange, Rodney L. Dunn, Anna M. Ray, Kathleen A. Cooney +2 more

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

UNC Libraries(2020)10.17615/vn1s-8a35

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0DataRank · unranked

0 citations

Frank J.A. van Rooij, Raha Pazoki, Albert Hofman, Nathan Pankratz, Richard A. Gibbs +51 more

Imputation of Exome Sequence Variants into Population- Based Samples and Blood-Cell-Trait-Associated Loci in African Americans: NHLBI GO Exome Sequencing Project

UNC Libraries(2020)10.17615/gafw-pc57

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Santhi K. Ganesh, Ethan M. Lange, Keolu Fox, Nora Franceschini, Robert B. Wallace +17 more

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

UNC Libraries(2020)10.17615/a384-d483

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0DataRank · unranked

0 citations

Jerome I. Rotter, Alex P. Reiner, André G. Uitterlinden, Gonçalo R. Abecasis, Digna R. Velez Edwards +95 more

A Meta-Analysis and Genome-Wide Association Study of Platelet Count and Mean Platelet Volume in African Americans

UNC Libraries(2020)10.17615/04pm-t231

N/A

0DataRank · unranked

0 citations

Elad Ziv, Michael A. Nalls, Rehan Qayyum, Andrew B. Singleton, Benjamin A. Logsdon +18 more

Association Studies with Imputed Variants Using Expectation-Maximization Likelihood-Ratio Tests

UNC Libraries(2020)10.17615/takt-vv35

N/A

0DataRank · unranked

0 citations

Karen L. Mohlke, Wei Sun, Mengjie Chen, Leslie A. Lange, Yun Li +2 more

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

UNC Libraries(2020)10.17615/ebqa-yt43

N/A

0DataRank · unranked

0 citations

Elisabeth Widén, Nicole M. Warrington, Paul Elliott, Nabila Bouatia‐Naji, Philippe Froguel +27 more

Association of Exome Sequences With Cardiovascular Traits among Blacks in the Jackson Heart Study

UNC Libraries(2020)10.17615/a9gj-5z87

N/A

0DataRank · unranked

0 citations

Alex P. Reiner, Mark J. Daly, James G. Wilson, Hao Mei, Joshua D. Smith +14 more

Polymorphisms of the HNF1A Gene Encoding Hepatocyte Nuclear Factor-1α are Associated with C-Reactive Protein

UNC Libraries(2020)10.17615/w18n-ks35

N/A

0DataRank · unranked

0 citations

Matthew Stephens, Yongtao Guan, Gregory M. Cooper, J. Peter Durda, Joshua D. Smith +13 more

Single-nucleotide polymorphisms at five loci are associated with C-reactive protein levels in a cohort of Filipino young adults

UNC Libraries(2020)10.17615/72ee-y271

N/A

0DataRank · unranked

0 citations

Karen L. Mohlke, Qin Li, Thomas W. McDade, Leslie A. Lange, Ghenadie Curocichin +5 more

Plasma Levels of Soluble Interleukin-2 Receptor αSignificance: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan

UNC Libraries(2020)10.17615/b656-qf11

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0DataRank · unranked

0 citations

Russell P. Tracy, Tamara B. Harris, Ethan M. Lange, Mike A. Nalls, Nancy S. Jenny +11 more

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

UNC Libraries(2020)10.17615/m864-xv86

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0DataRank · unranked

0 citations

Lisa R. Yanek, Kjell Nikus, Salman M. Tajuddin, Jussi Hernesniemi, Dawn Waterworth +95 more

Population-specific coding variant underlies genome-wide association with adiponectin level

UNC Libraries(2020)10.17615/yty3-p481

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0 citations

Leslie A. Lange, Ying Wu, Terry P. Combs, Damien C. Croteau‐Chonka, Marie P. Fogarty +9 more

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

UNC Libraries(2020)10.17615/s8sd-h432

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Todd L. Edwards, Jin Li, John M. Starr, Eric Boerwinkle, Yingchang Lu +92 more

Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration

UNC Libraries(2020)10.17615/wr3c-2b58

N/A

0DataRank · unranked

0 citations

Brendan J. Keating, Fotios Drenos, Vinicius Tragante, Folkert W. Asselbergs, Matthew B. Lanktree +12 more

Imputation of coding variants in African Americans: better performance using data from the exome sequencing project

UNC Libraries(2020)10.17615/8p33-rs54

N/A

0DataRank · unranked

0 citations

Alex P. Reiner, Lisa Warsinger Martin, Loı̈c Le Marchand, Steven Buyske, Gonçalo R. Abecasis +30 more

A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome

UNC Libraries(2020)10.17615/svad-an83

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0DataRank · unranked

0 citations

Albert M. Levin, James Graham Wilson, Tina V. Hartert, Christopher O. Olopade, H. Richard Johnston +57 more

Enhanced Statistical Tests for GWAS in Admixed Populations: Assessment using African Americans from CARe and a Breast Cancer Consortium

UNC Libraries(2020)10.17615/3jdw-6426

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0DataRank · unranked

0 citations

Leslie A. Lange, Michael F. Press, Elisa V. Bandera, L. Adrienne Cupples, Solomon K. Musani +27 more

Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium

UNC Libraries(2020)10.17615/xrs5-6v14

N/A

0DataRank · unranked

0 citations

James Wilson, Bouwe P. Krijthe, Nicholas L. Smith, Susan R. Heckbert, Kerri L. Wiggins +27 more

Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation

UNC Libraries(2020)10.17615/frhz-yk87

N/A

0DataRank · unranked

0 citations

Juan M. Peralta, Olivia Weeks, Gudnason, Vilmunder, Kurt Lohman, Andrew D. Johnson +63 more

Testing Genetic Association With Rare Variants in Admixed Populations: Rare Variant Analysis in Admixed Populations

UNC Libraries(2020)10.17615/7yv1-m916

N/A

0DataRank · unranked

0 citations

Yun Li, Xianyun Mao, Mingyao Li, Leslie A. Lange

Genome-Wide Association Study of White Blood Cell Count in 16,388 African Americans: the Continental Origins and Genetic Epidemiology Network (COGENT)

UNC Libraries(2020)10.17615/wn5h-av49

N/A

0DataRank · unranked

0 citations

David Couper, Struan F.A. Grant, Tamara B. Harris, Santhi K. Ganesh, Sampath Arepalli +27 more

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

UNC Libraries(2020)10.17615/pc2a-ev84

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0 citations

Jeanette Erdmann, Paul L. Auer, Robert Roberts, John Danesh, Deborah Farlow +27 more

Genome-wide Comparison of African-Ancestry Populations from CARe and Other Cohorts Reveals Signals of Natural Selection

UNC Libraries(2020)10.17615/hjj0-4367

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0 citations

Pardis C. Sabeti, Leslie A. Lange, Josyf C. Mychaleckyj, George Papanicolaou, Noah Zaitlen +27 more

Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults

UNC Libraries(2020)10.17615/73za-5242

N/A

0DataRank · unranked

0 citations

Amanda F. Marvelle, Thomas W. McDade, Yunfei Wang, Damien C. Croteau‐Chonka, Judith B. Borja +9 more

Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults

UNC Libraries(2020)10.17615/aycf-t384

N/A

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0 citations

Andrea Z. LaCroix, Pui–Yan Kwok, Amy M. Matteini, Nir Barzilai, Gil Atzmon +11 more

Multi-omics subtyping pipeline for chronic obstructive pulmonary disease

PLoS ONE(2021)10.1371/journal.pone.0255337

N/A

0DataRank · unranked

50 citations

Shahab Helmi, Evan Stene, Katherine Pratte, Yonghua Zhuang, Ronald P. Schuyler +7 more

Presence and transmission of mitochondrial heteroplasmic mutations in human populations of European and African ancestry

Mitochondrion(2021)10.1016/j.mito.2021.07.004

N/A

0DataRank · unranked

23 citations

Jessica L. Fetterman, Yong Qian, Xianbang Sun, Thomas W. Blackwell, Achilleas Pitsillides +14 more

Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche

Human Reproduction(2021)10.1093/humrep/deab086

N/A

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15 citations

Diana L. Cousminer, Nora Franceschini, Laura M. Raffield, Guochong Jia, Lindsay Fernández‐Rhodes +20 more

Moderate to vigorous physical activity interactions with genetic variants and body mass index in a large US ethnically diverse cohort

UNC Libraries(2021)10.17615/5hgj-vr53

N/A

0DataRank · unranked

5 citations

P. Gordon-Larsen, E.M. Lange, K.M. Harris, A.S. Richardson, Karen L. Mohlke +4 more

Peripheral Blood Cytopenia and Risk of Cardiovascular Disease and Mortality

Journal of the American Heart Association(2021)10.1161/jaha.121.020809

N/A

0DataRank · unranked

4 citations

Insu Koh, Marguerite R. Irvin, Leslie A. Lange, Damon E. Houghton, Diego Adrianzen Herrera +5 more

Leslie A. Lange

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