Paul A. James

Also affiliated with Peter MacCallum Cancer Centre

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

2.3Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly

Nature Communications(2020)10.1038/s41467-019-14079-0

Top 9%

2.3DataRank

Top 9%76 citations

Paul Lacaze, Emma M. Rath, Andrew Stone, Marie‐Jo Brion, Adam Ameur +33 more

Papers

Driven by 32 papers — median percentile 91. Top paper: “A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study”.

A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study

The Lancet Oncology(2021)10.1016/s1470-2045(21)00522-2

N/A

3.0DataRank · unranked

96 citations

Elizabeth Page, Mark N. Brook, Sarah Thomas, Natalie Taylor, Jennifer Pope +95 more

The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly

Nature Communications(2020)10.1038/s41467-019-14079-0

Top 9%

2.3DataRank

Top 9%76 citations

Paul Lacaze, Emma M. Rath, Andrew Stone, Marie‐Jo Brion, Adam Ameur +33 more

Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers

Communications Biology(2022)10.1038/s42003-022-03978-6

N/A

0.607DataRank · unranked

15 citations

John F. Pearson, Louise Marquart, Joe Dennis, George A. R. Wiggins, Daniel R. Barnes +95 more

Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-22-1206

N/A

0.464DataRank · unranked

21 citations

Kylie L. Gorringe, Matthew J. Wakefield, Adelyn Bolithon, Chi Nam Ignatius Pang, Derek S. Chiu +95 more

Common Susceptibility Loci for Male Breast Cancer

JNCI Journal of the National Cancer Institute(2020)10.1093/jnci/djaa101

N/A

0.457DataRank · unranked

20 citations

Eleni Perraki, Katarzyna Tomczyk, Michael E. Jones, Olivia Fletcher, Matthew Pugh +38 more

Specifications of the ACMG/AMP variant interpretation guidelines for germline TP53 variants

medRxiv(2020)10.1101/2020.04.25.20078931

N/A

0DataRank · unranked

5 citations

Kristy Lee, Magali Olivier, Tina Pesaran, Phuong L. Mai, Kelvin C. de Andrade +18 more

The genetic analysis of a founder Northern American population of European descent identifies FANCI as a candidate familial ovarian cancer risk gene

medRxiv(2020)10.1101/2020.05.04.20090407

N/A

0DataRank · unranked

2 citations

Laure Guitton-Sert, Wejdan M. Alenezi, Timothée Revil, Kathleen Klein Oros, Karine Bédard +21 more

Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study

The Lancet Oncology(2021)10.1016/s1470-2045(21)00189-3

N/A

0DataRank · unranked

121 citations

James G. Dowty, Jeanette C. Reece, Grant Lee, Allyson Templeton, John‐Paul Plazzer +95 more

Breast and Prostate Cancer Risks for MaleBRCA1andBRCA2Pathogenic Variant Carriers Using Polygenic Risk Scores

JNCI Journal of the National Cancer Institute(2021)10.1093/jnci/djab147

N/A

0DataRank · unranked

44 citations

Valentina Silvestri, Goska Leslie, Lesley McGuffog, Joe Dennis, Xin Yang +95 more

Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants

Genetics in Medicine(2021)10.1016/j.gim.2021.08.016

N/A

0DataRank · unranked

30 citations

Christoph Engel, Miguel de la Hoya, Paolo Peterlongo, Drakoulis Yannoukakos, Luca Livraghi +56 more

Polygenic score modifies risk for Alzheimer's disease in APOE ε4 homozygotes at phenotypic extremes

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2021)10.1002/dad2.12226

N/A

0DataRank · unranked

18 citations

Brian Fulton‐Howard, Moeen Riaz, Simon M. Laws, Robert Sebra, Joanne Ryan +11 more

A functionally impaired missense variant identified in French Canadian families implicates FANCI as a candidate ovarian cancer-predisposing gene

Genome Medicine(2021)10.1186/s13073-021-00998-5

N/A

0DataRank · unranked

22 citations

Laure Guitton-Sert, Wejdan M. Alenezi, Timothée Revil, Kathleen Klein Oros, Yuandi Gao +25 more

Genetic variants associated with inherited cardiovascular disorders among 13,131 asymptomatic older adults of European descent

npj Genomic Medicine(2021)10.1038/s41525-021-00211-x

N/A

0DataRank · unranked

20 citations

Robert Sebra, Moeen Riaz, Jodie Ingles, Jane Tiller, Bryony A. Thompson +9 more

Genomic Risk Prediction for Breast Cancer in Older Women

Cancers(2021)10.3390/cancers13143533

N/A

0DataRank · unranked

10 citations

Andrew Bakshi, Moeen Riaz, Suzanne G. Orchard, Jane Tiller, Franz–Josef Neumann +24 more

Genomic risk prediction for breast cancer in older women

medRxiv(2021)10.1101/2021.05.03.21256567

N/A

0DataRank · unranked

0 citations

Andrew Bakshi, Moeen Riaz, Suzanne G. Orchard, Jane Tiller, Franz–Josef Neumann +24 more

PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants

Research Square(2022)10.21203/rs.3.rs-2269143/v1

N/A

0DataRank · unranked

0 citations

Anna Morra, Sofia Khan, Daniel R. Barnes, Manjeet K. Bolla, Joe Dennis +64 more

Management of individuals with germline pathogenic/likely pathogenic variants in CHEK2: A clinical practice resource of the American College of Medical Genetics and Genomics (ACMG)

Genetics in Medicine(2023)10.1016/j.gim.2023.100870

N/A

0DataRank · unranked

83 citations

Esteban Astiazarán-Symonds, Laura M. Amendola, Judith Balmañà, William D. Foulkes, Paul A. James +9 more

The clinical and genomic landscape of patients with DDX41 variants identified during diagnostic sequencing

Blood Advances(2023)10.1182/bloodadvances.2023011389

N/A

0DataRank · unranked

28 citations

Nikita Mehta, Ryan A. Chisholm, Stephan Hütter, Constance Baer, Niroshan Nadarajah +9 more

Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2

British Journal of Cancer(2023)10.1038/s41416-023-02263-5

N/A

0DataRank · unranked

19 citations

Susan J. Ramus, Melissa C. Southey, Nicola S. Meagher, Andreas Hadjisavvas, Esther M. John +87 more

PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants

npj Breast Cancer(2023)10.1038/s41523-023-00546-x

N/A

0DataRank · unranked

7 citations

Anna Morra, Sofia Khan, Daniel R. Barnes, Manjeet K. Bolla, Joe Dennis +65 more

A Likelihood Ratio Approach for Utilizing Case-Control Data in the Clinical Classification of Rare Sequence Variants: Application to BRCA1 and BRCA2

Human Mutation(2023)10.1155/2023/9961341

N/A

0DataRank · unranked

7 citations

Denise G O'Mahony, Michael T. Parsons, Hongyan Li, Joe Dennis, Kristiina Aittomäkkiki +95 more

Challenges and approaches to calibrating patient phenotype as evidence for cancer gene variant classification under ACMG/AMP guidelines

Human Molecular Genetics(2024)10.1093/hmg/ddae009

N/A

0DataRank · unranked

7 citations

Kyriaki Michailidou, Michael T. Parsons, Jill S. Dolinsky, Tina Pesaran, Amal Yussuf +11 more

Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk

medRxiv(2024)10.1101/2024.02.29.24303243

N/A

0DataRank · unranked

3 citations

Jonathan P. Tyrer, Joe Dennis, Goska Leslie, Manjeet K. Bolla, Michael Lush +95 more

Titin-related familial dilated cardiomyopathy: factors associated with disease onset

European Heart Journal(2025)10.1093/eurheartj/ehaf380

N/A

0DataRank · unranked

9 citations

Robert A. Fletcher, Stacey Peters, Monique Ohanian, Magdalena Soka, Andrei Smolnikov +95 more

Management of individuals with heterozygous germline pathogenic variants in RAD51C, RAD51D, and BRIP1: A clinical practice resource of the American College of Medical Genetics and Genomics (ACMG)

Genetics in Medicine(2025)10.1016/j.gim.2025.101557

N/A

0DataRank · unranked

5 citations

Jianbang Chiang, Esteban Astiazarán-Symonds, Judith Balmañà, Ilana Cass, F. Kommoss +13 more

A quantitative, Bayesian-informed approach to gene-specific variant classification: Updated Expert Panel recommendations improve classification of TP53 germline variants for Li-Fraumeni syndrome

Genome Medicine(2025)10.1186/s13073-025-01536-3

N/A

0DataRank · unranked

5 citations

Megan N. Frone, Jessica L. Mester, Miguel de la Hoya, Phuong L. Mai, Tina Pesaran +32 more

Specifications of the ACMG/AMP variant interpretation guidelines for germline TP53 variants

Human Mutation(2020)10.1002/humu.24152

N/A

0DataRank · unranked

166 citations

Kristy Lee, Magali Olivier, Tina Pesaran, Phuong L. Mai, Kelvin C. de Andrade +19 more

Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer

npj Genomic Medicine(2025)10.1038/s41525-025-00529-w

N/A

0DataRank · unranked

0 citations

Jonathan P. Tyrer, Joe Dennis, Goska Leslie, Manjeet K. Bolla, Michael Lush +95 more

Characterization of the Cancer Spectrum in Men With GermlineBRCA1andBRCA2Pathogenic Variants

JAMA Oncology(2020)10.1001/jamaoncol.2020.2134

N/A

0DataRank · unranked

67 citations

Goska Leslie, Daniel R. Barnes, and the CIMBA Group, Bjarni A. Agnarsson, Kristiina Aittomäki +95 more

Expanding the clinical and genetic spectrum of ALPK3 variants: Phenotypes identified in pediatric cardiomyopathy patients and adults with heterozygous variants

American Heart Journal(2020)10.1016/j.ahj.2020.03.023

N/A

0DataRank · unranked

50 citations

Judith M.A. Verhagen, Raquel Yotti, Alireza Haghighi, Dean Phelan, Paul A. James +27 more

Suggested application of HER2+ breast tumor phenotype for germline TP53 variant classification within ACMG/AMP guidelines

Human Mutation(2020)10.1002/humu.24060

N/A

0DataRank · unranked

23 citations

Jessica L. Mester, Tina Pesaran, Jeffrey N. Weitzel, Jill S. Dolinsky, Amal Yussuf +13 more

Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer

npj Breast Cancer(2020)10.1038/s41523-020-00185-6

N/A

0DataRank · unranked

10 citations

Sofia Khan, Rainer Fagerholm, Kristiina Aittomäki, Julie M. Cunningham, Joe Dennis +39 more

Paul A. James

Indexed papers

Top data-sharing exemplar

Papers