Zhihua Chen

Second Affiliated Hospital of Zhejiang University

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Characterization of the human skin resistome and identification of two microbiota cutotypes

Microbiome(2021)10.1186/s40168-020-00995-7

Top 28%

0.719DataRank

Top 28%120 citations

Jingjing Xia, Liuyiqi Jiang, Yimei Tan, Yitai An, Xingyu Zhu +16 more

Papers

Driven by 21 papers — median percentile 0. Top paper: “Phase I Study of Taminadenant (PBF509/NIR178), an Adenosine 2A Receptor Antagonist, with or without Spartalizumab (PDR001), in Patients with Advanced Non–Small Cell Lung Cancer”.

Phase I Study of Taminadenant (PBF509/NIR178), an Adenosine 2A Receptor Antagonist, with or without Spartalizumab (PDR001), in Patients with Advanced Non–Small Cell Lung Cancer

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-21-2742

N/A

1.8DataRank · unranked

70 citations

Ben Creelan, Tawee Tanvetyanon, Jhanelle E. Gray, Eric B. Haura, Ram Thapa +13 more

Characterization of the human skin resistome and identification of two microbiota cutotypes

Microbiome(2021)10.1186/s40168-020-00995-7

Top 28%

0.719DataRank

Top 28%120 citations

Jingjing Xia, Liuyiqi Jiang, Yimei Tan, Yitai An, Xingyu Zhu +16 more

Targeted Therapy Given after Anti–PD-1 Leads to Prolonged Responses in Mouse Melanoma Models through Sustained Antitumor Immunity

Cancer Immunology Research(2021)10.1158/2326-6066.cir-20-0905

N/A

0DataRank · unranked

48 citations

Zhihua Chen, Jiannong Li, Eslam Mohamed, Michael A. Davies, Inna Smalley +15 more

Functional analysis of the 1p34.3 risk locus implicates GNL2 in high-grade serous ovarian cancer

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.11.020

N/A

0DataRank · unranked

18 citations

Brett M. Reid, Ann Chen, Zhihua Chen, Ellen L. Goode, Jennifer B. Permuth +10 more

The β8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development

Development(2022)10.1242/dev.200472

N/A

0DataRank · unranked

21 citations

John E. Morales, Zhihua Chen, S. Sebastian, Joseph H. McCarty, Arpan De

A preclinical model of patient-derived cerebrospinal fluid circulating tumor cells for experimental therapeutics in leptomeningeal disease from melanoma

Neuro-Oncology(2022)10.1093/neuonc/noac054

N/A

0DataRank · unranked

18 citations

Zhihua Chen, Francesca Vena, Inna Smalley, Robert Macaulay, Brittany Evernden +16 more

HAP40 is a conserved central regulator of Huntingtin and a potential modulator of Huntington’s disease pathogenesis

PLoS Genetics(2022)10.1371/journal.pgen.1010302

N/A

0DataRank · unranked

16 citations

Gang Li, Xin Ye, Dongsheng Chen, Zhihua Chen, Zhen Xu +13 more

HepaCAM Suppresses Glioblastoma Stem Cell Invasion in the Brain

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.24.504654

N/A

0DataRank · unranked

3 citations

John Lattier, John E. Morales, Jack R. Kelly, Xiaofeng Zheng, Zhihua Chen +5 more

Differential requirements for CD4+ T cells in the efficacy of the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain metastasis models

Journal for ImmunoTherapy of Cancer(2023)10.1136/jitc-2023-007239

N/A

0DataRank · unranked

15 citations

Jiannong Li, Zhihua Chen, Paulo C. Rodrı́guez, Jay K. Mandula, Lilit Karapetyan +4 more

Branched-chain keto acids promote an immune-suppressive and neurodegenerative microenvironment in leptomeningeal disease

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.18.572239

N/A

0DataRank · unranked

1 citations

Yuan Ren, Ronak Kundalia, Hasan Alhaddad, Zhihua Chen, Gerald Wallace +17 more

Data from Phase I Study of Taminadenant (PBF509/NIR178), an Adenosine 2A Receptor Antagonist, with or without Spartalizumab (PDR001), in Patients with Advanced Non–Small Cell Lung Cancer

(2023)10.1158/1078-0432.c.6531020

N/A

0DataRank · unranked

0 citations

Ben Creelan, Tawee Tanvetyanon, Jhanelle E. Gray, Eric B. Haura, R. K. Thapa +13 more

Data from Phase I Study of Taminadenant (PBF509/NIR178), an Adenosine 2A Receptor Antagonist, with or without Spartalizumab (PDR001), in Patients with Advanced Non–Small Cell Lung Cancer

(2023)10.1158/1078-0432.c.6531020.v1

N/A

0DataRank · unranked

0 citations

Ben Creelan, Tawee Tanvetyanon, Jhanelle E. Gray, Eric B. Haura, R. K. Thapa +13 more

Data from Single-Cell Characterization of the Immune Microenvironment of Melanoma Brain and Leptomeningeal Metastases

(2023)10.1158/1078-0432.c.6530586.v1

Top 100%

0DataRank

Top 100%0 citations

Zhihua Chen, Manali Phadke, Jiannong Li, Xiaoqing Yu, Clayton Wyatt +15 more

Supplementary Table 5 from Single-Cell Characterization of the Immune Microenvironment of Melanoma Brain and Leptomeningeal Metastases

(2023)10.1158/1078-0432.22480995

Top 100%

0DataRank

Top 100%0 citations

Zhihua Chen, Manali Phadke, Jiannong Li, Xiaoqing Yu, Clayton Wyatt +15 more

Data from Targeted Therapy Given after Anti–PD-1 Leads to Prolonged Responses in Mouse Melanoma Models through Sustained Antitumor Immunity

(2023)10.1158/2326-6066.c.6550279.v1

N/A

0DataRank · unranked

0 citations

Zhihua Chen, Jiannong Li, Eslam Mohamed, Michael A. Davies, Inna Smalley +15 more

Defining the mechanisms of action and resistance to the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain models

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.14.536907

N/A

0DataRank · unranked

0 citations

Jiannong Li, Zhihua Chen, Paulo C. Rodrı́guez, Jay K. Mandula, Lilit Karapetyan +4 more

Integrative single cell RNA and spatial profiling identify mechanisms of neonatal brain hemorrhage pathophysiology and repair

Angiogenesis(2025)10.1007/s10456-025-10019-3

N/A

0DataRank · unranked

2 citations

Zhihua Chen, Ali Pirani, Arpan De, Zachary Wise, Xiaofeng Zheng +3 more

1695eP Systematic evaluation of polygenic risk scores (PRS) for autoimmune thyroid disease and the risk of thyroiditis following checkpoint immunotherapy (ICI) of melanoma in a North American patient (pt) population

Annals of Oncology(2025)10.1016/j.annonc.2025.08.2322

N/A

0DataRank · unranked

0 citations

Zhihua Chen, Seok-Joo Lee, F.S. Hodi, Yuying Li, Howard Streicher +5 more

HAP40 is a conserved central regulator of Huntingtin and a specific modulator of mutant Huntingtin toxicity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.27.119552

N/A

0DataRank · unranked

4 citations

Gang� Li, Xin Ye, Dongsheng Chen, Zhihua Chen, Zhen Xu +5 more

Cmss1 limits FMDV infection by enhancing antigen presentation and CD8 + T cell responses

Journal of Virology(2025)10.1128/jvi.01249-25

N/A

0DataRank · unranked

0 citations

Lihong Zhang, Jieru Deng, Linlin Zheng, Zhihua Chen, Zhao Zhang +4 more

Single-Cell Characterization of the Immune Microenvironment of Melanoma Brain and Leptomeningeal Metastases

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-21-1694

N/A

0DataRank · unranked

166 citations

Zhihua Chen, Manali Phadke, Jiannong Li, Xiaoqing Yu, Clayton Wyatt +15 more

Zhihua Chen

Indexed papers

Top data-sharing exemplar

Papers