Lars C. Pedersen

Biochemistry, Genetics and Molecular BiologyChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 56 papers. Top paper: “Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase γ”.

Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase γ

Nucleic Acids Research(2024)10.1093/nar/gkae670

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0.378DataRank · unranked

7 citations

Jonathan Bouvette, Lars C. Pedersen, Shruti Somai, Robert Dutcher, Mario J. Borgnia +2 more

The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00546

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0DataRank · unranked

15 citations

Scott A. Gabel, Lars C. Pedersen, Eugene F. DeRose, J.M. Krahn, Elizabeth E. Howell +2 more

DNA polymerase mu: An inflexible scaffold for substrate flexibility

DNA repair(2020)10.1016/j.dnarep.2020.102932

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0DataRank · unranked

5 citations

Katarzyna Bębenek, Lars C. Pedersen, Thomas A. Kunkel, Andrea M. Kaminski

Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break

Nature Communications(2020)10.1038/s41467-020-18506-5

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0DataRank · unranked

10 citations

John M. Pryor, Dale A. Ramsden, Thomas A. Kunkel, Lars C. Pedersen, Katarzyna Bębenek +1 more

Anticoagulant heparan sulfate: structural specificity and biosynthesis

UNC Libraries(2020)10.17615/8mrw-2525

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4 citations

Lars C. Pedersen, Jian Li

Molecular Mechanism of Substrate Specificity for Heparan Sulfate 2- O -Sulfotransferase

UNC Libraries(2020)10.17615/d9xr-e616

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0DataRank · unranked

1 citations

Lars C. Pedersen, Wenfang Dou, Juzheng Sheng, Po-Hung Hsieh, Chunhui Liu +4 more

Amino Acid Substitution in the Active Site of DNA Polymerase β Explains the Energy Barrier of the Nucleotidyl Transfer Reaction

UNC Libraries(2020)10.17615/94rm-rk43

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0DataRank · unranked

0 citations

V.K. Batra, William A. Beard, Samuel H. Wilson, Ping Lin, Lars C. Pedersen +3 more

Engineering sulfotransferases to modify heparan sulfate

UNC Libraries(2020)10.17615/rs67-bm97

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0DataRank · unranked

0 citations

A.F. Moon, Jian Liu, Lars C. Pedersen, Danyin Song, Ding Xu

Energy analysis of chemistry for correct insertion by DNA polymerase beta

UNC Libraries(2020)10.17615/z883-ea70

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0 citations

V. K. Batra, S. H. Wilson, L. G. Pedersen, W. A. Beard, P. Lin +1 more

Clinical and Molecular Characteristics of Post-Colonoscopy Colorectal Cancer: A Population-based Study

UNC Libraries(2020)10.17615/9drm-9v36

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0 citations

Elena M. Stoffel, Erika Koeppe, Henrik Toft Sørensen, Trine Frøslev, Lars C. Pedersen +5 more

Enzymatic Redesigning of Biologically Active Heparan Sulfate

UNC Libraries(2020)10.17615/c0yj-rz66

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0 citations

Lars C. Pedersen, Lynda M. McDowell, Jinghua Chen, Eva Muñoz, Robert J. Linhardt +4 more

Explicit Water Near the Catalytic I Helix Thr in the Predicted Solution Structure of CYP2A4

UNC Libraries(2020)10.17615/x4x7-bt80

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0DataRank · unranked

0 citations

Tom Darden, L. Perera, Lee G. Pedersen, Anna Gorokhov, Eric F. Johnson +2 more

Heparan Sulfate Biosynthesis: A Theoretical Study of the Initial Sulfation Step by N-Deacetylase/N-Sulfotransferase

UNC Libraries(2020)10.17615/rg60-9t15

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0 citations

L. Perera, Lars C. Pedersen, Lee G. Pedersen, Anna Gorokhov, Masahiko Negishi +1 more

Incorrect nucleotide insertion at the active site of a G:A mismatch catalyzed by DNA polymerase

UNC Libraries(2020)10.17615/0b5c-9t97

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0DataRank · unranked

0 citations

Lars C. Pedersen, L. G. Pedersen, W. A. Beard, P. Lin, V. K. Batra +1 more

Development and validation of a registry-based definition of eosinophilic esophagitis in Denmark

UNC Libraries(2020)10.17615/012e-wp16

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0DataRank · unranked

0 citations

Rune Erichsen, Nicholas J. Shaheen, Lars C. Pedersen, Evan S. Dellon, Mogens Vyberg +2 more

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu

UNC Libraries(2020)10.17615/4kxm-4z54

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0DataRank · unranked

0 citations

A.F. Moon, Dale A. Ramsden, John M. Pryor, Lars C. Pedersen, Katarzyna Bębenek +1 more

Role of Deacetylase Activity of N -Deacetylase/ N -Sulfotransferase 1 in Forming N -Sulfated Domain in Heparan Sulfate

UNC Libraries(2020)10.17615/bf1y-e534

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0DataRank · unranked

0 citations

Wenfang Dou, Vijayakanth Pagadala, Lars C. Pedersen, Jian Liu, Yongmei Xu

Structural Analysis of the Sulfotransferase (3- O -Sulfotransferase Isoform 3) Involved in the Biosynthesis of an Entry Receptor for Herpes Simplex Virus 1

UNC Libraries(2020)10.17615/fnwt-g812

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0 citations

Suzanne C. Edavettal, Masahiko Negishi, A.F. Moon, Lars C. Pedersen, Robert J. Linhardt +3 more

A comparison of BRCT domains involved in nonhomologous end-joining: Introducing the solution structure of the BRCT domain of polymerase lambda

UNC Libraries(2020)10.17615/rz00-2s96

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0DataRank · unranked

0 citations

Dale A. Ramsden, Eugene F. DeRose, Jody M. Havener, Lars C. Pedersen, A.F. Moon +2 more

Sustained active site rigidity during synthesis by human DNA polymerase μ

UNC Libraries(2020)10.17615/p4p6-d872

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0DataRank · unranked

0 citations

Katarzyna Bębenek, A.F. Moon, Lars C. Pedersen, Thomas A. Kunkel, John M. Pryor +1 more

Inhibitors of Streptococcus pneumoniae Surface Endonuclease EndA Discovered by High-Throughput Screening Using a PicoGreen Fluorescence Assay

UNC Libraries(2020)10.17615/hqb8-rh27

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0DataRank · unranked

0 citations

Marika Midon, William P. Janzen, Scott F. Singleton, Alfred Pingoud, Lars C. Pedersen +3 more

Deciphering the substrate recognition mechanisms of the heparan sulfate 3- O -sulfotransferase-3

RSC Chemical Biology(2021)10.1039/d1cb00079a

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0DataRank · unranked

17 citations

Andrea M. Kaminski, Yongmei Xu, Vijayakanth Pagadala, J.M. Krahn, Truong Quang Pham +3 more

Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate

ACS Catalysis(2021)10.1021/acscatal.1c04520

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0DataRank · unranked

14 citations

Andrea M. Kaminski, Zhangjie Wang, Eduardo Stancanelli, Yongmei Xu, Vijayakanth Pagadala +6 more

The mosquito protein AEG12 displays both cytolytic and antiviral properties via a common lipid transfer mechanism

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2019251118

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18 citations

Peter M. Thompson, Shih‐Heng Chen, Ramesh Jadi, Brianna Lupo, Eugene F. DeRose +8 more

Structural Insights into the Specificity of 8-Oxo-7,8-dihydro-2′-deoxyguanosine Bypass by Family X DNA Polymerases

Genes(2021)10.3390/genes13010015

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0DataRank · unranked

4 citations

Thomas A. Kunkel, Lars C. Pedersen, Katarzyna Bębenek, Andrea M. Kaminski

Understanding the substrate specificity of the heparan sulfate sulfotransferases by an integrated biosynthetic and crystallographic approach

UNC Libraries(2021)10.17615/v0ht-3f28

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0DataRank · unranked

1 citations

Lars C. Pedersen, Andrea Moon, Juzheng Sheng, Jian Liu

Crystal Structure and Mutational Analysis of Heparan Sulfate 3- O -Sulfotransferase Isoform 1

UNC Libraries(2021)10.17615/8bv4-dh41

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0DataRank · unranked

0 citations

Masahiko Negishi, Karen A. Lee, Jian Liu, Lars C. Pedersen, Suzanne C. Edavettal +1 more

Mutational Study of Heparan Sulfate 2- O -Sulfotransferase and Chondroitin Sulfate 2- O -Sulfotransferase

UNC Libraries(2021)10.17615/v6be-aw53

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0DataRank · unranked

0 citations

Jian Liu, Ding Xu, Lars C. Pedersen, Danyin Song

From Steroid and Drug Metabolism to Glycobiology, Using Sulfotransferase Structures to Understand and Tailor Function

Drug Metabolism and Disposition(2022)10.1124/dmd.121.000478

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0DataRank · unranked

23 citations

MyeongJin Yi, Lee G. Pedersen, Andrea M. Kaminski, Lars C. Pedersen

Emerging chemical and biochemical tools for studying 3-O-sulfated heparan sulfate

American Journal of Physiology-Cell Physiology(2022)10.1152/ajpcell.00110.2022

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0DataRank · unranked

19 citations

Lars C. Pedersen, Jian Liu

Analysis of diverse double-strand break synapsis with Polλ reveals basis for unique substrate specificity in nonhomologous end-joining

Nature Communications(2022)10.1038/s41467-022-31278-4

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0DataRank · unranked

12 citations

Kishore K. Chiruvella, Dale A. Ramsden, Katarzyna Bębenek, Thomas A. Kunkel, Lars C. Pedersen +1 more

A genome-wide CRISPR-Cas9 knockout screen reveals FSP1 as warfarin-resistant vitamin K reductase

Research Square(2022)10.21203/rs.3.rs-2039668/v1

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0DataRank · unranked

2 citations

Xuejie Chen, Yizhou Liu, Craig M. Williams, Lars C. Pedersen, Darrel W. Stafford +2 more

A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase

Nature Communications(2023)10.1038/s41467-023-36446-8

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0DataRank · unranked

71 citations

Xuejie Chen, Yizhou Liu, Craig M. Williams, Lars C. Pedersen, Darrel W. Stafford +2 more

Immunotherapy-induced neutralizing antibodies disrupt allergen binding and sustain allergen tolerance in peanut allergy

Journal of Clinical Investigation(2023)10.1172/jci164501

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0DataRank · unranked

50 citations

Jungki Min, Tarun Keswani, Crystal Richardson, Kwasi Amoako, Jingjia Zhou +10 more

Increased 3- O -sulfated heparan sulfate in Alzheimer’s disease brain is associated with genetic risk gene HS3ST1

Science Advances(2023)10.1126/sciadv.adf6232

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0DataRank · unranked

39 citations

Vaishali Patel, Xuehong Song, Yongmei Xu, Andrea M. Kaminski, Vivien Uyen Doan +12 more

Targeting heparan sulfate-protein interactions with oligosaccharides and monoclonal antibodies

Frontiers in Molecular Biosciences(2023)10.3389/fmolb.2023.1194293

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12 citations

Lars C. Pedersen, Ding Xu, Miaomiao Li

Design of an Ara h 2 hypoallergen from conformational epitopes

Clinical & Experimental Allergy(2024)10.1111/cea.14433

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22 citations

Tarun Keswani, Nicole A. LaHood, Isabelle R. Lytle, Orlee Marini‐Rapoport, Léna Andrieux +9 more

Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7

Frontiers in Allergy(2023)10.3389/falgy.2023.1133412

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0DataRank · unranked

8 citations

Alexander C. Y. Foo, Scott A. Gabel, L. Perera, Eugene F. DeRose, Anna Pomés +3 more

Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

eLife(2023)10.7554/elife.90192

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0DataRank · unranked

3 citations

Huanmeng Hao, Zhangjie Wang, Chih Yean Ong, Robert Dutcher, Yongmei Xu +4 more

Targeting the Structural Maturation Pathway of HIV-1 Reverse Transcriptase

Biomolecules(2023)10.3390/biom13111603

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0DataRank · unranked

2 citations

Scott A. Gabel, Eugene F. DeRose, L. Perera, J.M. Krahn, Lars C. Pedersen +2 more

Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.26.550758

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0DataRank · unranked

0 citations

Huanmeng Hao, Zhangjie Wang, Chihyean Ong, Robert Dutcher, Yongmei Xu +4 more

Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

(2023)10.7554/elife.90192.1

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0DataRank · unranked

0 citations

Huanmeng Hao, Zhangjie Wang, Chihyean Ong, Robert Dutcher, Yongmei Xu +4 more

Reviewer #1 (Public Review): Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

(2023)10.7554/elife.90192.2.sa1

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0 citations

Huanmeng Hao, Zhangjie Wang, Chihyean Ong, Robert Dutcher, Yongmei Xu +4 more

Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

(2023)10.7554/elife.90192.2

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0DataRank · unranked

0 citations

Huanmeng Hao, Zhangjie Wang, Chihyean Ong, Robert Dutcher, Yongmei Xu +4 more

Neutralizing IgG4 antibodies are a biomarker of sustained efficacy after peanut oral immunotherapy

Journal of Allergy and Clinical Immunology(2024)10.1016/j.jaci.2024.02.017

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0DataRank · unranked

28 citations

Nicole A. LaHood, Orlee Marini‐Rapoport, Bijoya Karmakar, Léna Andrieux, Brian B. Reese +5 more

Defining the cross-reactivity between peanut allergens Ara h 2 and Ara h 6 using monoclonal antibodies

Clinical & Experimental Immunology(2024)10.1093/cei/uxae005

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14 citations

Monica L. Fernández‐Quintero, Tarun Keswani, Guangning Zong, Jane Shim, Lars C. Pedersen +3 more

Heparan sulfate selectively inhibits the collagenase activity of cathepsin K

Matrix Biology(2024)10.1016/j.matbio.2024.03.005

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0DataRank · unranked

13 citations

Yin Luo, Huanmeng Hao, J.M. Krahn, Guowei Su, Robert Dutcher +5 more

Structural and Functional Analysis of Heparosan Synthase 2 from Pasteurella multocida to Improve the Synthesis of Heparin

ACS Catalysis(2024)10.1021/acscatal.4c00677

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0DataRank · unranked

7 citations

Juno A. Krahn, Elizabeth Viverette, Robert Dutcher, Vijayakanth Pagadala, Mario J. Borgnia +3 more

DNA polymerase λ Loop1 variant yields unexpected gain-of-function capabilities in nonhomologous end-joining

DNA repair(2024)10.1016/j.dnarep.2024.103645

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2 citations

Kishore K. Chiruvella, Dale A. Ramsden, Katarzyna Bębenek, Thomas A. Kunkel, Lars C. Pedersen +1 more

Heparan sulfate selectively inhibits the collagenase activity of cathepsin K

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.05.574350

N/A

0DataRank · unranked

1 citations

Yin Luo, Huanmeng Hao, J.M. Krahn, Guowei Su, Robert Dutcher +5 more

Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

UNC Libraries(2024)10.17615/5heh-tr09

N/A

0DataRank · unranked

0 citations

Zhangjie Wang, Chih Yean Ong, Ding Xu, Jian Liu, Lars C. Pedersen +4 more

Germline-encoded recognition of peanut underlies development of convergent antibodies in humans

Science Translational Medicine(2025)10.1126/scitranslmed.adw4148

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4 citations

Léna Andrieux, Tarun Keswani, Guangning Zong, Dylan Duchen, Gur Yaari +20 more

Molecular basis for RNA discrimination by human DNA ligase 1

Nucleic Acids Research(2025)10.1093/nar/gkaf299

N/A

0DataRank · unranked

1 citations

Thomas J. Jurkiw, J.M. Krahn, Neha V Bokil, Suzanne J. Admiraal, Lars C. Pedersen +5 more

Nonhomologous end-joining uses distinct mechanisms to repair each strand of a double strand break

Nature Communications(2025)10.1038/s41467-025-66528-8

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0DataRank · unranked

1 citations

Kishore K. Chiruvella, Andrea M. Kaminski, Thomas A. Kunkel, Lars C. Pedersen, Dale A. Ramsden +1 more

Using engineered 6- O -sulfotransferase to improve the synthesis of anticoagulant heparin

Organic & Biomolecular Chemistry(2020)10.1039/d0ob01736a

N/A

0DataRank · unranked

16 citations

Yongmei Xu, Andrea M. Kaminski, Xiaobing Chang, Vijayakanth Pagadala, Maurice Horton +8 more

End Processing in NHEJ by Polymerase λ and PNKP is coordinated during short-range synapsis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.25.656038

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0DataRank · unranked

3 citations

Andrea M. Kaminski, Lars C. Pedersen, Tasmin Naila, Alan E. Tomkinson, Susan P. Lees‐Miller +3 more