David Ayares

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 31 papers. Top paper: “Integrative multi-omics profiling in human decedents receiving pig heart xenografts”.

Integrative multi-omics profiling in human decedents receiving pig heart xenografts

Nature Medicine(2024)10.1038/s41591-024-02972-1

N/A

2.1DataRank · unranked

56 citations

Brian D. Piening, Maedeh Mohebnasab, Bo Xia, Chenchen Zhu, Jeffrey Stern +54 more

Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months

Xenotransplantation(2022)10.1111/xen.12744

N/A

0.737DataRank · unranked

135 citations

Corbin E. Goerlich, Avneesh K. Singh, Tianshu Zhang, Ivan Tatarov, Billeta Lewis +20 more

Old World Monkeys are less than ideal transplantation models for testing pig organs lacking three carbohydrate antigens (Triple-Knockout)

Scientific Reports(2020)10.1038/s41598-020-66311-3

N/A

0.717DataRank · unranked

118 citations

Hayato Iwase, Diyan Patel, Abhijit Jagdale, David Ayares, Douglas J. Anderson +4 more

Transplantation of a genetically modified porcine heart into a live human

Nature Medicine(2025)10.1038/s41591-024-03429-1

N/A

0.681DataRank · unranked

93 citations

Alison Grazioli, Avneesh K. Singh, Andy Tully, Javier Galindo, Kapil Saharia +32 more

Initial evidence that blockade of the CD40/CD154 costimulation pathway alone is sufficient as maintenance therapy in xenotransplantation

Xenotransplantation(2021)10.1111/xen.12721

N/A

0.625DataRank · unranked

20 citations

Jeremy B. Foote, Mariyam Javed, Huy Nguyen, Mohamed H. Bikhet, Christophe Hansen‐Estruch +3 more

Novel factors potentially initiating acute antibody‐mediated rejection in pig kidney xenografts despite an efficient immunosuppressive regimen

Xenotransplantation(2024)10.1111/xen.12859

N/A

0.449DataRank · unranked

19 citations

Akihiro Maenaka, Ivy A. Rosales, Ahmad Karadagi, Toshihide Tomosugi, David Ayares +7 more

Multi-omics analysis of a pig-to-human decedent kidney xenotransplant

Nature(2025)10.1038/s41586-025-09846-7

N/A

0.437DataRank · unranked

16 citations

Brian D. Piening, Alexa K. Dowdell, Maedeh Mohebnasab, Simon H. Williams, Alexey Stukalov +71 more

Cardiac and Pulmonary Histopathology in Baboons Following Genetically-Engineered Pig Orthotopic Heart Transplantation

Annals of Transplantation(2022)10.12659/aot.935338

N/A

0.385DataRank · unranked

12 citations

Jeremy B. Foote, Abhijit Jagdale, Gregory P. Walcott, Hayato Iwase, Mohamed H. Bikhet +14 more

Expression of human thrombomodulin by GalTKO.hCD46 pigs modulates coagulation cascade activation by endothelial cells and during ex vivo lung perfusion with human blood

Xenotransplantation(2023)10.1111/xen.12828

N/A

0.373DataRank · unranked

11 citations

Zhuo Gao, Andrea N. Riner, Evelyn Sievert, Donald G. Harris, Kasinath Kuravi +14 more

Knock‐out of N‐glycolylneuraminic acid attenuates antibody‐mediated rejection in xenogenically perfused porcine lungs

Xenotransplantation(2022)10.1111/xen.12784

N/A

0.330DataRank · unranked

8 citations

Zahra Habibabady, Wessam Hassanein, Margaret R. Connolly, Lars Burdorf, Emily Redding +13 more

Integrative Multi-omic Profiling of Two Human Decedents Receiving Pig Heart Xenografts Reveals Strong Perturbations in Early Immune-Cell and Cellular Metabolism Responses

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.05.543406

N/A

0.208DataRank · unranked

3 citations

Brian D. Piening, Bo Xia, Chenchen Zhu, Jeffrey Stern, Weimin Zhang +45 more

The Renin‐Angiotensin System after Pig Kidney Transplantation in Baboons

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.l7769

N/A

0DataRank · unranked

2 citations

Christophe Hansen‐Estruch, Mohamed H. Bikhet, Mariyam Javed, Akemi Katsurada, Ryousuke Satou +5 more

Observations on hydronephrosis after pig kidney transplantation in baboons

Xenotransplantation(2022)10.1111/xen.12779

N/A

0DataRank · unranked

1 citations

Mohamed H. Bikhet, Christophe Hansen‐Estruch, Mariyam Javed, David Ayares, Hidetaka Hara +4 more

Renin-angiotensin-aldosterone system function in the pig-to-baboon kidney xenotransplantation model

American Journal of Transplantation(2023)10.1016/j.ajt.2022.11.022

N/A

0DataRank · unranked

29 citations

Mohamed H. Bikhet, Mariyam Javed, Akemi Katsurada, Ryousuke Satou, Weijian Shao +6 more

Assessment of glomerular filtration and tubular secretion in baboons with life‐supporting pig kidney grafts

Xenotransplantation(2023)10.1111/xen.12795

N/A

0DataRank · unranked

15 citations

Mohamed H. Bikhet, Imam H. Shaik, Vignesh Vasudevan, Wenchen Zhao, Mariyam Javed +6 more

De novo membranous nephropathy in a pig-to-baboon kidney xenograft: A new xenograft glomerulopathy

American Journal of Transplantation(2023)10.1016/j.ajt.2023.08.016

N/A

0DataRank · unranked

9 citations

Kohei Kinoshita, Akihiro Maenaka, Ira Doressa Anne L. How, Martin K. Selig, Christina M. Laguerre +5 more

In vitro and in vivo immune assessments of genetically‐engineered pig skin grafts in New World (squirrel) monkeys

Xenotransplantation(2023)10.1111/xen.12832

N/A

0DataRank · unranked

3 citations

Jeremy B. Foote, Christophe Hansen‐Estruch, Mohamed H. Bikhet, Huy Nguyen, Mariyam Javed +7 more

Extended survival of 9- and 10-gene-edited pig heart xenografts with ischemia minimization and CD154 costimulation blockade-based immunosuppression

The Journal of Heart and Lung Transplantation(2024)10.1016/j.healun.2024.07.022

N/A

0DataRank · unranked

13 citations

Ikechukwu Ileka, Gannon McGrath, Kohei Kinoshita, Zahra Habibabady, Madelyn Ma +21 more

Pigs in Transplantation Research and Their Potential as Sources of Organs in Clinical Xenotransplantation

Comparative Medicine(2024)10.30802/aalas-cm-23-000030

N/A

0DataRank · unranked

7 citations

Hidetaka Hara, W.H. Eyestone, David Ayares, David C. Cleveland, David K.C. Cooper +1 more

Genetically engineered pig heart transplantation in non-human primates

Communications Medicine(2025)10.1038/s43856-025-00731-y

N/A

0DataRank · unranked

19 citations

Corbin E. Goerlich, Tianshu Zhang, Billeta Lewis, Alena Hershfeld, Gheorghe Braileanu +14 more

Coordinated circulating and tissue-based T cell responses precede xenograft rejection

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.07.687259

N/A

0DataRank · unranked

0 citations

Elizabeth Severa, Han Chen, Elizabeth Doepke, Fiorella Chacon, Farshid Fathi +24 more

Antibody reactivity with new antigens revealed in multi‐transgenic triple knockout pigs may cause early loss of pig kidneys in baboons

Xenotransplantation(2020)10.1111/xen.12642

N/A

0DataRank · unranked

27 citations

Kazuhiro Takeuchi, Thomas Pomposelli, Dilrukshi Ekanayake‐Alper, Akira Shimizu, Lennan Boyd +10 more

Effect of intravenous immunoglobulin (IVIg) on primate complement-dependent cytotoxicity of genetically engineered pig cells: relevance to clinical xenotransplantation

Scientific Reports(2020)10.1038/s41598-020-68505-1

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0DataRank · unranked

26 citations

Yehua Cui, Diyan Patel, Abhijit Jagdale, Hayato Iwase, David Ayares +3 more

Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models

Xenotransplantation(2021)10.1111/xen.12712

N/A

0DataRank · unranked

38 citations

Kasinath Kuravi, Lars Burdorf, Lori Sorrells, Benson Morrill, Arielle Cimeno +13 more

Blood Cardioplegia Induction, Perfusion Storage and Graft Dysfunction in Cardiac Xenotransplantation

Frontiers in Immunology(2021)10.3389/fimmu.2021.667093

N/A

0DataRank · unranked

38 citations

Bartley P. Griffith, Avneesh K. Singh, Mohamed Abdullah, Shreya Singireddy, Irina Kolesnik +14 more

Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons

Xenotransplantation(2021)10.1111/xen.12715

N/A

0DataRank · unranked

20 citations

Abhijit Jagdale, Takayuki Yamamoto, Hidetaka Hara, Mohamed H. Bikhet, Henk‐Jan Schuurman +9 more

Evidence that sensitization to triple‐knockout pig cells will not be detrimental to subsequent allotransplantation

Xenotransplantation(2021)10.1111/xen.12701

N/A

0DataRank · unranked

15 citations

Huy Nguyen, Zheng‐Yu Wang, Abhijit Jagdale, Mohamed H. Bikhet, Takayuki Yamamoto +4 more

Stable expression of the human thrombomodulin transgene in pig endothelial cells is associated with a reduction in the inflammatory response

Cytokine(2021)10.1016/j.cyto.2021.155580

N/A

0DataRank · unranked

11 citations

Hayato Iwase, Huy Nguyen, Yuko Miyagawa, Kasinath Kuravi, Jeremy B. Foote +5 more

The Role of Interleukin-6 (IL-6) in the Systemic Inflammatory Response in Xenograft Recipients and in Pig Kidney Xenograft Failure

Frontiers in Immunology(2021)10.3389/fimmu.2021.788949

N/A

0DataRank · unranked

15 citations

Hayato Iwase, Qi Li, Takayuki Yamamoto, Abhijit Jagdale, Mohamed Ezzelarab +5 more

Genetically Modified Porcine-to-Human Cardiac Xenotransplantation

New England Journal of Medicine(2022)10.1056/nejmoa2201422

N/A

0DataRank · unranked

687 citations

Corbin E. Goerlich, Avneesh K. Singh, Martine Rothblatt, Christine L. Lau, Aakash Shah +8 more

T and B lymphocyte dynamics after genetically-modified pig-to-baboon kidney xenotransplantation with an anti-CD40mAb-based immunosuppressive regimen

Transplant Immunology(2022)10.1016/j.trim.2022.101545

N/A

0DataRank · unranked

11 citations

Huy Nguyen, Hayato Iwase, Jeremy B. Foote, Takayuki Yamamoto, Mariyam Javed +6 more